@article{Sunagawa.2013.24141494,
  author = {Sunagawa, S and Mende, DR and Zeller, G and Izquierdo-Carrasco, F and Berger, SA and Kultima, JR and Coelho, LP and Arumugam, M and Tap, J and Nielsen, HB and Rasmussen, S and Brunak, S and Pedersen, O and Guarner, F and de Vos, WM and Wang, J and Li, J and Doré, J and Ehrlich, SD and Stamatakis, A and Bork, P},
  title = {{Metagenomic species profiling using universal phylogenetic marker genes}},
  journal = {Nature methods},
  pages = {},
  year = {2013},
  url = {http://www.ncbi.nlm.nih.gov/pubmed/24141494},
  abstract = {{To quantify known and unknown microorganisms at species-level resolution using shotgun sequencing data, we developed a method that establishes metagenomic operational taxonomic units (mOTUs) based on single-copy phylogenetic marker genes. Applied to 252 human fecal samples, the method revealed that on average 43% of the species abundance and 58% of the richness cannot be captured by current reference genome-based methods. An implementation of the method is available at http://www.bork.embl.de/software/mOTU/.}}
}