| Gene | Molecular function | Biological process | Cellular component |
FOL1
|
- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity (GO:0003848)
- dihydroneopterin aldolase activity (GO:0004150)
- dihydropteroate synthase activity (GO:0004156)
|
- folic acid and derivative biosynthesis (GO:0009396)
|
- cytoplasm (GO:0005737)
- mitochondrion (GO:0005739)
- mitochondrial membrane (GO:0005740)
|
ADE3
|
- formate-tetrahydrofolate ligase activity (GO:0004329)
- methenyltetrahydrofolate cyclohydrolase activity (GO:0004477)
- methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488)
|
- folic acid and derivative metabolism (GO:0006760)
- purine base biosynthesis (GO:0009113)
|
- nucleus (GO:0005634)
- cytoplasm (GO:0005737)
|
FAU1
|
- 5-formyltetrahydrofolate cyclo-ligase activity (GO:0030272)
|
- folic acid and derivative biosynthesis (GO:0009396)
|
- mitochondrion (GO:0005739)
|
GCV1
|
|
- glycine metabolism (GO:0006544)
- glycine catabolism (GO:0006546)
- one-carbon compound metabolism (GO:0006730)
|
- mitochondrion (GO:0005739)
- glycine cleavage complex (GO:0005960)
|
MIS1
|
- formate-tetrahydrofolate ligase activity (GO:0004329)
- methenyltetrahydrofolate cyclohydrolase activity (GO:0004477)
- methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488)
|
- conversion of met-tRNAf to fmet-tRNA (GO:0001718)
- nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0006139)
- acetate biosynthesis from carbon monoxide (GO:0019415)
- purine fermentation (GO:0019653)
- folic acid biosynthesis (GO:0046656)
|
- mitochondrion (GO:0005739)
|
SHM1
|
- glycine hydroxymethyltransferase activity (GO:0004372)
|
- one-carbon compound metabolism (GO:0006730)
|
- mitochondrion (GO:0005739)
|
MET12
|
- methylenetetrahydrofolate reductase (NADPH) activity (GO:0004489)
|
- methionine metabolism (GO:0006555)
|
|
GCV2
|
|
- glycine catabolism (GO:0006546)
- one-carbon compound metabolism (GO:0006730)
|
- mitochondrion (GO:0005739)
- glycine cleavage complex (GO:0005960)
|
GCV3
|
|
- glycine catabolism (GO:0006546)
- one-carbon compound metabolism (GO:0006730)
|
- mitochondrion (GO:0005739)
- glycine cleavage complex (GO:0005960)
|
MET13
|
- structural constituent of ribosome (GO:0003735)
- methylenetetrahydrofolate reductase (NADPH) activity (GO:0004489)
|
- sulfur amino acid biosynthesis (GO:0000097)
- methionine metabolism (GO:0006555)
|
- cytoplasm (GO:0005737)
- mitochondrion (GO:0005739)
|