Clusters

 


Explanation of Gene ontology symbols
cluster_1 (n = 14)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial electron transport, cytochrome c to oxygenGO:00061231071.43%0.15%2.91E-29(4.7E-26)
electron transportGO:00061181178.57%0.48%1.51E-24(2.45E-21)
ATP synthesis coupled electron transportGO:00427731071.43%0.39%9.43E-23(1.52E-19)
ATP synthesis coupled electron transport (sensu Eukaryota)GO:00427751071.43%0.39%9.43E-23(1.52E-19)
oxidative phosphorylationGO:00061191071.43%0.71%1.16E-19(1.88E-16)
cellular respirationGO:00453331178.57%1.35%4.89E-19(7.9E-16)
aerobic respirationGO:00090601071.43%1.27%5.97E-17(9.65E-14)
generation of precursor metabolites and energyGO:00060911285.71%3.5%2.17E-16(3.51E-13)
energy derivation by oxidation of organic compoundsGO:00159801178.57%3.04%5.14E-15(8.31E-12)
phosphorylationGO:00163101071.43%2.21%1.93E-14(3.11E-11)
phosphate metabolismGO:00067961071.43%2.91%3.13E-13(5.06E-10)
phosphorus metabolismGO:00067931071.43%2.91%3.13E-13(5.06E-10)
transportGO:00068101178.57%14.27%1.14E-7(1.84E-4)
establishment of localizationGO:00512341178.57%14.39%1.25E-7(2.01E-4)
localizationGO:00511791178.57%14.82%1.71E-7(2.76E-4)
cellular metabolismGO:00442371392.86%52.12%1.5E-3(n.s)
metabolismGO:00081521392.86%52.93%1.8E-3(n.s)
anaerobic respirationGO:000906117.14%0.05%6.49E-3(n.s)
physiological processGO:000758214100%73.68%0.01(n.s)
cytochrome c oxidase complex assemblyGO:000853517.14%0.14%0.02(n.s)
cellular physiological processGO:00508751392.86%71.65%0.06(n.s)
cellular processGO:00099871392.86%72.29%0.07(n.s)
protein complex assemblyGO:000646117.14%2.26%0.27(n.s)
response to stressGO:000695017.14%6.09%0.59(n.s)
response to stimulusGO:005089617.14%8.41%0.71(n.s)
cellular protein metabolismGO:004426717.14%21.7%0.97(n.s)
protein metabolismGO:001953817.14%22.06%0.97(n.s)
cellular macromolecule metabolismGO:004426017.14%24.52%0.98(n.s)
macromolecule metabolismGO:004317017.14%26.04%0.99(n.s)
biological_processGO:000815014100%99.98%1(n.s)
primary metabolismGO:004423817.14%48.71%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
heme-copper terminal oxidase activityGO:00150021285.71%0.19%8.4E-36(1.36E-32)
oxidoreductase activity, acting on heme group of donorsGO:00166751285.71%0.19%8.4E-36(1.36E-32)
oxidoreductase activity, acting on heme group of donors, oxygen as acceptorGO:00166761285.71%0.19%8.4E-36(1.36E-32)
cytochrome-c oxidase activityGO:00041291285.71%0.19%8.4E-36(1.36E-32)
primary active transporter activityGO:00153991285.71%0.77%1.01E-24(1.63E-21)
hydrogen ion transporter activityGO:00150781285.71%0.84%2.85E-24(4.6E-21)
monovalent inorganic cation transporter activityGO:00150771285.71%0.88%5.86E-24(9.48E-21)
carrier activityGO:00053861392.86%1.64%4.09E-23(6.61E-20)
cation transporter activityGO:00083241285.71%1.89%1.06E-19(1.71E-16)
ion transporter activityGO:00150751285.71%2.21%7.68E-19(1.24E-15)
oxidoreductase activityGO:00164911392.86%3.73%2.69E-18(4.35E-15)
transporter activityGO:00052151392.86%6.64%5.46E-15(8.82E-12)
catalytic activityGO:00038241392.86%29.21%1.12E-6(1.81E-3)
oxidoreductase activity, acting on other nitrogenous compounds as donorsGO:001666117.14%0.02%**
nitric oxide reductase activityGO:001696617.14%0.02%**
electron carrier activityGO:000905517.14%0.08%0.01(n.s)
electron transporter activityGO:000548917.14%0.34%0.05(n.s)
enzyme regulator activityGO:003023417.14%2.54%0.3(n.s)
molecular_functionGO:000367414100%99.44%0.92(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
respiratory chain complex IVGO:00452771285.71%0.19%8.4E-36(1.36E-32)
respiratory chain complex IV (sensu Eukaryota)GO:00057511285.71%0.19%8.4E-36(1.36E-32)
mitochondrial electron transport chainGO:00057461285.71%0.4%8.08E-29(1.31E-25)
mitochondrial inner membraneGO:00057431285.71%2.43%2.45E-18(3.96E-15)
inner membraneGO:00198661285.71%2.43%2.45E-18(3.96E-15)
mitochondrial membraneGO:00057401285.71%3.16%6.19E-17(1E-13)
mitochondrionGO:000573914100%15.78%5.52E-12(8.92E-9)
organelle membraneGO:00310901285.71%8.58%1.11E-11(1.79E-8)
membraneGO:00160201285.71%15.38%1.11E-8(1.8E-5)
protein complexGO:00432341285.71%21.07%4.36E-7(7.04E-4)
cytoplasmGO:000573714100%55.64%2.69E-4(0.44)
intracellular membrane-bound organelleGO:004323114100%55.65%2.7E-4(0.44)
membrane-bound organelleGO:004322714100%55.65%2.7E-4(0.44)
organelleGO:004322614100%60.56%8.85E-4(n.s)
intracellular organelleGO:004322914100%60.56%8.85E-4(n.s)
intracellularGO:000562214100%77.03%0.03(n.s)
mitochondrial intermembrane spaceGO:000575817.14%0.39%0.05(n.s)
cellGO:000562314100%83.5%0.08(n.s)
mitochondrial matrixGO:000575917.14%2.52%0.3(n.s)
cytosolGO:000582917.14%10.08%0.77(n.s)
cellular_componentGO:000557514100%99.61%0.95(n.s)

 

 

cluster_132 (n = 13)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein biosynthesisGO:000641213100%12.16%1.16E-12(1.88E-9)
macromolecule biosynthesisGO:000905913100%13.04%2.91E-12(4.71E-9)
cellular biosynthesisGO:004424913100%17.05%9.73E-11(1.57E-7)
biosynthesisGO:000905813100%18.28%2.41E-10(3.89E-7)
cellular protein metabolismGO:004426713100%21.7%2.27E-9(3.66E-6)
protein metabolismGO:001953813100%22.06%2.8E-9(4.53E-6)
cellular macromolecule metabolismGO:004426013100%24.52%1.12E-8(1.8E-5)
macromolecule metabolismGO:004317013100%26.04%2.44E-8(3.95E-5)
ribosomal small subunit assembly and maintenanceGO:0000028323.08%0.2%1.8E-6(2.91E-3)
primary metabolismGO:004423813100%48.71%8.59E-5(0.14)
ribosomal subunit assemblyGO:0042257323.08%0.81%1.33E-4(0.22)
cellular metabolismGO:004423713100%52.12%2.07E-4(0.33)
ribosome assemblyGO:0042255323.08%0.99%2.48E-4(0.4)
metabolismGO:000815213100%52.93%2.53E-4(0.41)
cytoplasm organization and biogenesisGO:0007028430.77%3.9%1.23E-3(n.s)
ribosome biogenesis and assemblyGO:0042254430.77%3.9%1.23E-3(n.s)
ribosomal small subunit-nucleus exportGO:000005617.69%0.02%**
protein complex assemblyGO:0006461323.08%2.26%2.74E-3(n.s)
processing of 20S pre-rRNAGO:0030490215.38%0.71%3.69E-3(n.s)
ribosome biogenesisGO:0007046323.08%3.3%7.93E-3(n.s)
cellular physiological processGO:005087513100%71.65%0.01(n.s)
cellular processGO:000998713100%72.29%0.01(n.s)
physiological processGO:000758213100%73.68%0.02(n.s)
ribosome-nucleus exportGO:000005417.69%0.25%0.03(n.s)
rRNA processingGO:0006364215.38%2.71%0.05(n.s)
protein-nucleus exportGO:000661117.69%0.68%0.09(n.s)
rRNA metabolismGO:0016072215.38%3.92%0.09(n.s)
organelle organization and biogenesisGO:0006996430.77%15.69%0.13(n.s)
RNA processingGO:0006396215.38%5.33%0.15(n.s)
nuclear exportGO:005116817.69%1.29%0.15(n.s)
nuclear transportGO:005116917.69%1.53%0.18(n.s)
nucleocytoplasmic transportGO:000691317.69%1.63%0.19(n.s)
cell organization and biogenesisGO:0016043430.77%17.98%0.19(n.s)
RNA metabolismGO:0016070215.38%8.32%0.3(n.s)
protein targetingGO:000660517.69%3.42%0.36(n.s)
intracellular protein transportGO:000688617.69%3.7%0.39(n.s)
protein transportGO:001503117.69%3.79%0.4(n.s)
establishment of protein localizationGO:004518417.69%3.95%0.41(n.s)
protein localizationGO:000810417.69%4.37%0.44(n.s)
intracellular transportGO:004690717.69%7.53%0.64(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139215.38%23.17%0.84(n.s)
transportGO:000681017.69%14.27%0.87(n.s)
establishment of localizationGO:005123417.69%14.39%0.87(n.s)
biopolymer metabolismGO:0043283215.38%25.06%0.87(n.s)
localizationGO:005117917.69%14.82%0.88(n.s)
biological_processGO:000815013100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
structural constituent of ribosomeGO:000373513100%3.58%1.13E-19(1.83E-16)
structural molecule activityGO:000519813100%5.51%3.53E-17(5.71E-14)
RNA bindingGO:0003723323.08%5.96%0.04(n.s)
nucleic acid bindingGO:0003676323.08%9.87%0.13(n.s)
bindingGO:0005488323.08%17.35%0.4(n.s)
molecular_functionGO:000367413100%99.44%0.93(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytosolic ribosome (sensu Eukaryota)GO:000583013100%2.65%2E-21(3.24E-18)
ribosomeGO:000584013100%4.4%1.77E-18(2.86E-15)
ribonucleoprotein complexGO:003052913100%7.19%1.17E-15(1.88E-12)
cytosolGO:000582913100%10.08%1E-13(1.62E-10)
intracellular non-membrane-bound organelleGO:004323213100%14.3%9.69E-12(1.57E-8)
non-membrane-bound organelleGO:004322813100%14.3%9.69E-12(1.57E-8)
cytosolic small ribosomal subunit (sensu Eukaryota)GO:0005843753.85%0.98%9.81E-12(1.59E-8)
eukaryotic 48S initiation complexGO:0016283753.85%0.98%9.81E-12(1.59E-8)
eukaryotic 43S preinitiation complexGO:0016282753.85%1.13%2.87E-11(4.63E-8)
small ribosomal subunitGO:0015935753.85%1.52%2.38E-10(3.85E-7)
protein complexGO:004323413100%21.07%1.54E-9(2.48E-6)
cytosolic large ribosomal subunit (sensu Eukaryota)GO:0005842646.15%1.44%1.2E-8(1.94E-5)
large ribosomal subunitGO:0015934646.15%2.12%1.24E-7(2.01E-4)
cytoplasmGO:000573713100%55.64%4.85E-4(0.78)
organelleGO:004322613100%60.56%1.46E-3(n.s)
intracellular organelleGO:004322913100%60.56%1.46E-3(n.s)
small nucleolar ribonucleoprotein complexGO:0005732215.38%0.88%5.61E-3(n.s)
intracellularGO:000562213100%77.03%0.03(n.s)
cellGO:000562313100%83.5%0.1(n.s)
nucleolusGO:0005730215.38%4.58%0.12(n.s)
mitochondrionGO:0005739215.38%15.78%0.63(n.s)
nucleusGO:0005634323.08%31.01%0.82(n.s)
intracellular membrane-bound organelleGO:0043231538.46%55.65%0.94(n.s)
membrane-bound organelleGO:0043227538.46%55.65%0.94(n.s)
cellular_componentGO:000557513100%99.61%0.95(n.s)

 

 

cluster_24 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glutamine family amino acid metabolismGO:0009064360%0.67%2.73E-6(4.41E-3)
arginine biosynthesisGO:0006526240%0.15%2.15E-5(0.03)
pyrimidine base biosynthesisGO:0019856240%0.23%5.02E-5(0.08)
arginine metabolismGO:0006525240%0.23%5.02E-5(0.08)
urea cycle intermediate metabolismGO:0000051240%0.23%5.02E-5(0.08)
pyrimidine base metabolismGO:0006206240%0.26%6.5E-5(0.1)
nucleobase biosynthesisGO:0046112240%0.33%1E-4(0.16)
glutamine family amino acid biosynthesisGO:0009084240%0.37%1.32E-4(0.21)
amino acid metabolismGO:0006520360%2.82%2.11E-4(0.34)
nucleobase metabolismGO:0009112240%0.51%2.51E-4(0.41)
amino acid and derivative metabolismGO:0006519360%3.05%2.67E-4(0.43)
amine metabolismGO:0009308360%3.38%3.61E-4(0.58)
nitrogen compound metabolismGO:0006807360%3.66%4.57E-4(0.74)
aromatic compound metabolismGO:0006725240%0.88%7.53E-4(n.s)
citrate transportGO:0015746120%0.02%**
pyrimidine ribonucleoside triphosphate metabolismGO:0009208120%0.02%**
pyrimidine ribonucleotide biosynthesisGO:0009220120%0.02%**
CTP metabolismGO:0046036120%0.02%**
mitochondrial citrate transportGO:0006843120%0.02%**
pyrimidine ribonucleotide metabolismGO:0009218120%0.02%**
pyrimidine ribonucleoside triphosphate biosynthesisGO:0009209120%0.02%**
CTP biosynthesisGO:0006241120%0.02%**
organic acid metabolismGO:0006082360%4.6%9E-4(n.s)
carboxylic acid metabolismGO:0019752360%4.6%9E-4(n.s)
heterocycle metabolismGO:0046483240%1.1%1.17E-3(n.s)
tricarboxylic acid transportGO:0006842120%0.03%1.55E-3(n.s)
glutamine metabolismGO:0006541120%0.03%1.55E-3(n.s)
amino acid biosynthesisGO:0008652240%1.53%2.26E-3(n.s)
pyrimidine nucleoside triphosphate metabolismGO:0009147120%0.05%2.32E-3(n.s)
amine biosynthesisGO:0009309240%1.67%2.68E-3(n.s)
nitrogen compound biosynthesisGO:0044271240%1.67%2.68E-3(n.s)
pyrimidine nucleotide biosynthesisGO:0006221120%0.06%3.1E-3(n.s)
cellular biosynthesisGO:0044249480%17.05%3.64E-3(n.s)
pyrimidine nucleotide metabolismGO:0006220120%0.09%4.64E-3(n.s)
biosynthesisGO:0009058480%18.28%4.75E-3(n.s)
mitochondrial transportGO:0006839120%0.17%8.49E-3(n.s)
'de novo' pyrimidine base biosynthesisGO:0006207120%0.19%9.26E-3(n.s)
ribonucleoside triphosphate biosynthesisGO:0009201120%0.36%0.02(n.s)
ribonucleoside triphosphate metabolismGO:0009199120%0.36%0.02(n.s)
nucleoside triphosphate biosynthesisGO:0009142120%0.37%0.02(n.s)
nucleoside triphosphate metabolismGO:0009141120%0.39%0.02(n.s)
ribonucleotide biosynthesisGO:0009260120%0.59%0.03(n.s)
ribonucleotide metabolismGO:0009259120%0.62%0.03(n.s)
carboxylic acid transportGO:0046942120%0.77%0.04(n.s)
organic acid transportGO:0015849120%0.79%0.04(n.s)
phospholipid biosynthesisGO:0008654120%0.81%0.04(n.s)
nucleotide biosynthesisGO:0009165120%0.84%0.04(n.s)
membrane lipid biosynthesisGO:0046467120%1.1%0.05(n.s)
phospholipid metabolismGO:0006644120%1.19%0.06(n.s)
nucleotide metabolismGO:0009117120%1.38%0.07(n.s)
membrane lipid metabolismGO:0006643120%1.61%0.08(n.s)
lipid biosynthesisGO:0008610120%1.92%0.09(n.s)
cellular lipid metabolismGO:0044255120%3.16%0.15(n.s)
lipid metabolismGO:0006629120%3.38%0.16(n.s)
primary metabolismGO:0044238480%48.71%0.17(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
cellular metabolismGO:0044237480%52.12%0.22(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
metabolismGO:0008152480%52.93%0.23(n.s)
intracellular transportGO:0046907120%7.53%0.32(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139240%23.17%0.33(n.s)
transportGO:0006810120%14.27%0.54(n.s)
establishment of localizationGO:0051234120%14.39%0.54(n.s)
localizationGO:0051179120%14.82%0.55(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activityGO:0004088240%0.03%4.8E-7(7.76E-4)
carbamoyl-phosphate synthase activityGO:0004086240%0.03%4.8E-7(7.76E-4)
ligase activity, forming carbon-nitrogen bondsGO:0016879360%1.07%1.15E-5(0.02)
carbon-nitrogen ligase activity, with glutamine as amido-N-donorGO:0016884240%0.12%1.34E-5(0.02)
ligase activityGO:0016874360%1.89%6.41E-5(0.1)
aspartate carbamoyltransferase activityGO:0004070120%0.02%**
CTP synthase activityGO:0003883120%0.03%1.55E-3(n.s)
tricarboxylate carrier activityGO:0005371120%0.03%1.55E-3(n.s)
carboxyl- and carbamoyltransferase activityGO:0016743120%0.03%1.55E-3(n.s)
catalytic activityGO:0003824480%29.21%0.03(n.s)
porter activityGO:0015291120%0.59%0.03(n.s)
electrochemical potential-driven transporter activityGO:0015290120%0.59%0.03(n.s)
transferase activity, transferring one-carbon groupsGO:0016741120%1.13%0.06(n.s)
carrier activityGO:0005386120%1.64%0.08(n.s)
transporter activityGO:0005215120%6.64%0.29(n.s)
transferase activityGO:0016740120%10.13%0.41(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
carbamoyl-phosphate synthase complexGO:0005951240%0.03%4.8E-7(7.76E-4)
unlocalized protein complexGO:0005941240%0.57%3.16E-4(0.51)
mitochondrial inner membraneGO:0005743120%2.43%0.12(n.s)
inner membraneGO:0019866120%2.43%0.12(n.s)
mitochondrial membraneGO:0005740120%3.16%0.15(n.s)
mitochondrionGO:0005739240%15.78%0.18(n.s)
protein complexGO:0043234240%21.07%0.28(n.s)
organelle membraneGO:0031090120%8.58%0.36(n.s)
cytosolGO:0005829120%10.08%0.41(n.s)
membraneGO:0016020120%15.38%0.57(n.s)
cytoplasmGO:0005737360%55.64%0.6(n.s)
intracellular membrane-bound organelleGO:0043231240%55.65%0.88(n.s)
membrane-bound organelleGO:0043227240%55.65%0.88(n.s)
intracellularGO:0005622360%77.03%0.92(n.s)
organelleGO:0043226240%60.56%0.92(n.s)
intracellular organelleGO:0043229240%60.56%0.92(n.s)
cellGO:0005623360%83.5%0.97(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_27 (n = 6)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
double-strand break repair via nonhomologous end-joiningGO:0006303116.67%0.29%0.02(n.s)
non-recombinational repairGO:0000726116.67%0.43%0.03(n.s)
double-strand break repairGO:0006302116.67%0.64%0.04(n.s)
biological process unknownGO:0000004466.67%25.64%0.04(n.s)
aerobic respirationGO:0009060116.67%1.27%0.07(n.s)
cellular respirationGO:0045333116.67%1.35%0.08(n.s)
protein complex assemblyGO:0006461116.67%2.26%0.13(n.s)
DNA repairGO:0006281116.67%2.32%0.13(n.s)
response to DNA damage stimulusGO:0006974116.67%2.73%0.15(n.s)
response to endogenous stimulusGO:0009719116.67%2.82%0.16(n.s)
energy derivation by oxidation of organic compoundsGO:0015980116.67%3.04%0.17(n.s)
generation of precursor metabolites and energyGO:0006091116.67%3.5%0.19(n.s)
response to stressGO:0006950116.67%6.09%0.31(n.s)
response to stimulusGO:0050896116.67%8.41%0.41(n.s)
DNA metabolismGO:0006259116.67%8.58%0.42(n.s)
cellular protein metabolismGO:0044267116.67%21.7%0.77(n.s)
protein metabolismGO:0019538116.67%22.06%0.78(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139116.67%23.17%0.79(n.s)
cellular macromolecule metabolismGO:0044260116.67%24.52%0.82(n.s)
biopolymer metabolismGO:0043283116.67%25.06%0.82(n.s)
macromolecule metabolismGO:0043170116.67%26.04%0.84(n.s)
primary metabolismGO:0044238233.33%48.71%0.88(n.s)
cellular metabolismGO:0044237233.33%52.12%0.91(n.s)
metabolismGO:0008152233.33%52.93%0.92(n.s)
cellular physiological processGO:0050875233.33%71.65%0.99(n.s)
cellular processGO:0009987233.33%72.29%0.99(n.s)
physiological processGO:0007582233.33%73.68%0.99(n.s)
biological_processGO:00081506100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055546100%35.75%2.08E-3(n.s)
molecular_functionGO:00036746100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739583.33%15.78%5.07E-4(0.82)
intracellular membrane-bound organelleGO:00432316100%55.65%0.03(n.s)
membrane-bound organelleGO:00432276100%55.65%0.03(n.s)
organelleGO:00432266100%60.56%0.05(n.s)
intracellular organelleGO:00432296100%60.56%0.05(n.s)
mitochondrial inner membraneGO:0005743116.67%2.43%0.14(n.s)
inner membraneGO:0019866116.67%2.43%0.14(n.s)
cytoplasmGO:0005737583.33%55.64%0.17(n.s)
mitochondrial membraneGO:0005740116.67%3.16%0.18(n.s)
intracellularGO:00056226100%77.03%0.21(n.s)
cellGO:00056236100%83.5%0.34(n.s)
organelle membraneGO:0031090116.67%8.58%0.42(n.s)
membraneGO:0016020116.67%15.38%0.63(n.s)
nucleusGO:0005634116.67%31.01%0.89(n.s)
cellular_componentGO:00055756100%99.61%0.98(n.s)

 

 

cluster_20 (n = 13)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
metallo-sulfur cluster assemblyGO:0031163646.15%0.14%1.43E-15(2.32E-12)
iron-sulfur cluster assemblyGO:0016226646.15%0.14%1.43E-15(2.32E-12)
iron ion homeostasisGO:0006879753.85%0.45%2.85E-14(4.6E-11)
cofactor metabolismGO:0051186969.23%2.26%8.01E-13(1.29E-9)
transition metal ion homeostasisGO:0046916753.85%0.73%1.13E-12(1.83E-9)
di-, tri-valent inorganic cation homeostasisGO:0030005753.85%0.81%2.39E-12(3.87E-9)
metal ion homeostasisGO:0006875753.85%0.91%6.07E-12(9.81E-9)
cation homeostasisGO:0030003753.85%1.35%1.02E-10(1.64E-7)
cell ion homeostasisGO:0006873753.85%1.49%2.06E-10(3.32E-7)
ion homeostasisGO:0050801753.85%1.55%2.75E-10(4.45E-7)
cell homeostasisGO:0019725753.85%1.64%4.17E-10(6.74E-7)
homeostasisGO:0042592753.85%1.73%6.17E-10(9.97E-7)
heme a metabolismGO:0046160323.08%0.06%2.55E-8(4.12E-5)
heme a biosynthesisGO:0006784323.08%0.06%2.55E-8(4.12E-5)
pigment biosynthesisGO:0046148323.08%0.22%2.29E-6(3.71E-3)
porphyrin biosynthesisGO:0006779323.08%0.22%2.29E-6(3.71E-3)
heme biosynthesisGO:0006783323.08%0.22%2.29E-6(3.71E-3)
heme metabolismGO:0042168323.08%0.23%2.86E-6(4.63E-3)
porphyrin metabolismGO:0006778323.08%0.23%2.86E-6(4.63E-3)
pigment metabolismGO:0042440323.08%0.23%2.86E-6(4.63E-3)
secondary metabolismGO:0019748323.08%0.28%5.12E-6(8.27E-3)
cofactor biosynthesisGO:0051188323.08%1.08%3.23E-4(0.52)
heterocycle metabolismGO:0046483323.08%1.1%3.37E-4(0.54)
iron ion transportGO:0006826215.38%0.29%6.28E-4(n.s)
metal incorporation into metallo-sulfur clusterGO:001828217.69%0.02%**
iron incorporation into metallo-sulfur clusterGO:001828317.69%0.02%**
transition metal ion transportGO:0000041215.38%0.67%3.23E-3(n.s)
intracellular sequestering of iron ionGO:000688017.69%0.03%4.02E-3(n.s)
sequestering of metal ionGO:005123817.69%0.03%4.02E-3(n.s)
di-, tri-valent inorganic cation transportGO:0015674215.38%0.79%4.51E-3(n.s)
oxygen and reactive oxygen species metabolismGO:0006800215.38%0.82%4.87E-3(n.s)
metal ion transportGO:0030001215.38%0.87%5.42E-3(n.s)
cation transportGO:0006812215.38%1.36%0.01(n.s)
cellular physiological processGO:005087513100%71.65%0.01(n.s)
cellular processGO:000998713100%72.29%0.01(n.s)
cytochrome c oxidase complex assemblyGO:000853517.69%0.14%0.02(n.s)
ion transportGO:0006811215.38%1.64%0.02(n.s)
physiological processGO:000758213100%73.68%0.02(n.s)
maintenance of localizationGO:005123517.69%0.45%0.06(n.s)
cellular metabolismGO:00442371076.92%52.12%0.06(n.s)
metabolismGO:00081521076.92%52.93%0.07(n.s)
response to oxidative stressGO:000697917.69%0.79%0.1(n.s)
response to osmotic stressGO:000697017.69%0.91%0.11(n.s)
response to biotic stimulusGO:000960717.69%1.08%0.13(n.s)
DNA-dependent DNA replicationGO:000626117.69%1.24%0.15(n.s)
aerobic respirationGO:000906017.69%1.27%0.15(n.s)
cellular respirationGO:004533317.69%1.35%0.16(n.s)
DNA replicationGO:000626017.69%1.6%0.19(n.s)
protein complex assemblyGO:000646117.69%2.26%0.26(n.s)
localizationGO:0051179323.08%14.82%0.3(n.s)
energy derivation by oxidation of organic compoundsGO:001598017.69%3.04%0.33(n.s)
generation of precursor metabolites and energyGO:000609117.69%3.5%0.37(n.s)
response to abiotic stimulusGO:000962817.69%3.52%0.37(n.s)
cellular biosynthesisGO:0044249323.08%17.05%0.39(n.s)
response to external stimulusGO:000960517.69%3.87%0.4(n.s)
biosynthesisGO:0009058323.08%18.28%0.43(n.s)
response to stressGO:000695017.69%6.09%0.56(n.s)
transportGO:0006810215.38%14.27%0.57(n.s)
establishment of localizationGO:0051234215.38%14.39%0.58(n.s)
protein modificationGO:000646417.69%6.68%0.59(n.s)
response to stimulusGO:005089617.69%8.41%0.68(n.s)
DNA metabolismGO:000625917.69%8.58%0.69(n.s)
biopolymer modificationGO:004341217.69%9.25%0.72(n.s)
cellular protein metabolismGO:0044267215.38%21.7%0.81(n.s)
protein metabolismGO:0019538215.38%22.06%0.82(n.s)
cellular macromolecule metabolismGO:0044260215.38%24.52%0.87(n.s)
biopolymer metabolismGO:0043283215.38%25.06%0.87(n.s)
macromolecule metabolismGO:0043170215.38%26.04%0.89(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613917.69%23.17%0.97(n.s)
primary metabolismGO:0044238323.08%48.71%0.99(n.s)
biological_processGO:000815013100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
electron transporter activityGO:0005489215.38%0.34%8.45E-4(n.s)
oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptorGO:001673117.69%0.02%**
ferredoxin reductase activityGO:000893717.69%0.02%**
oxidoreductase activity, acting on iron-sulfur proteins as donorsGO:001673017.69%0.02%**
NADPH-adrenodoxin reductase activityGO:001503917.69%0.02%**
cystathionine gamma-lyase activityGO:000412317.69%0.03%4.02E-3(n.s)
electron carrier activityGO:000905517.69%0.08%0.01(n.s)
thiol-disulfide exchange intermediate activityGO:003050817.69%0.12%0.02(n.s)
disulfide oxidoreductase activityGO:001503617.69%0.14%0.02(n.s)
carbon-sulfur lyase activityGO:001684617.69%0.14%0.02(n.s)
chaperone bindingGO:005108717.69%0.17%0.02(n.s)
protein bindingGO:0005515323.08%7.39%0.07(n.s)
oxidoreductase activityGO:0016491215.38%3.73%0.08(n.s)
unfolded protein bindingGO:005108217.69%0.9%0.11(n.s)
lyase activityGO:001682917.69%1.27%0.15(n.s)
carrier activityGO:000538617.69%1.64%0.19(n.s)
transporter activityGO:0005215215.38%6.64%0.21(n.s)
enzyme regulator activityGO:003023417.69%2.54%0.28(n.s)
bindingGO:0005488323.08%17.35%0.4(n.s)
molecular function unknownGO:0005554430.77%35.75%0.74(n.s)
catalytic activityGO:0003824323.08%29.21%0.78(n.s)
molecular_functionGO:00036741292.31%99.44%1(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:000573913100%15.78%3.54E-11(5.72E-8)
mitochondrial matrixGO:0005759861.54%2.52%1.61E-10(2.6E-7)
cytoplasmGO:000573713100%55.64%4.85E-4(0.78)
intracellular membrane-bound organelleGO:004323113100%55.65%4.87E-4(0.79)
membrane-bound organelleGO:004322713100%55.65%4.87E-4(0.79)
organelleGO:004322613100%60.56%1.46E-3(n.s)
intracellular organelleGO:004322913100%60.56%1.46E-3(n.s)
intracellularGO:000562213100%77.03%0.03(n.s)
mitochondrial inner membraneGO:0005743215.38%2.43%0.04(n.s)
inner membraneGO:0019866215.38%2.43%0.04(n.s)
mitochondrial intermembrane spaceGO:000575817.69%0.39%0.05(n.s)
mitochondrial membraneGO:0005740215.38%3.16%0.06(n.s)
cellGO:000562313100%83.5%0.1(n.s)
organelle membraneGO:0031090215.38%8.58%0.31(n.s)
membraneGO:0016020215.38%15.38%0.62(n.s)
cellular_componentGO:000557513100%99.61%0.95(n.s)

 

 

cluster_22 (n = 8)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
posttranslational protein-membrane targetingGO:0006620450%0.12%6.76E-11(1.09E-7)
protein-ER targetingGO:0045047450%0.43%1.96E-8(3.16E-5)
protein-membrane targetingGO:0006612450%0.48%3.01E-8(4.86E-5)
SRP-dependent cotranslational protein-membrane targetingGO:0006614337.5%0.29%1.2E-6(1.94E-3)
secretory pathwayGO:0045045562.5%3.13%1.48E-6(2.39E-3)
secretionGO:0046903562.5%3.24%1.75E-6(2.83E-3)
cotranslational protein-membrane targetingGO:0006613337.5%0.34%1.9E-6(3.07E-3)
posttranslational protein membrane targeting, translocationGO:0031204225%0.06%8.05E-6(0.01)
SRP-dependent cotranslational protein-membrane targeting, translocationGO:0006616225%0.14%4.82E-5(0.08)
protein targetingGO:0006605450%3.42%8.4E-5(0.14)
intracellular transportGO:0046907562.5%7.53%1.1E-4(0.18)
intracellular protein transportGO:0006886450%3.7%1.14E-4(0.18)
protein transportGO:0015031450%3.79%1.26E-4(0.2)
establishment of protein localizationGO:0045184450%3.95%1.47E-4(0.24)
protein localizationGO:0008104450%4.37%2.17E-4(0.35)
asparaginyl-tRNA aminoacylationGO:0006421112.5%0.02%**
transportGO:0006810562.5%14.27%2.25E-3(n.s)
establishment of localizationGO:0051234562.5%14.39%2.34E-3(n.s)
localizationGO:0051179562.5%14.82%2.68E-3(n.s)
DNA replication checkpointGO:0000076112.5%0.08%6.18E-3(n.s)
protein secretionGO:0009306112.5%0.14%0.01(n.s)
karyogamy during conjugation with cellular fusionGO:0000742112.5%0.15%0.01(n.s)
response to unfolded proteinGO:0006986112.5%0.19%0.01(n.s)
karyogamyGO:0000741112.5%0.19%0.01(n.s)
organelle fusionGO:0048284112.5%0.26%0.02(n.s)
intra-Golgi transportGO:0006891112.5%0.33%0.03(n.s)
chromatin silencing at silent mating-type cassetteGO:0030466112.5%0.33%0.03(n.s)
GPI anchor biosynthesisGO:0006506112.5%0.36%0.03(n.s)
GPI anchor metabolismGO:0006505112.5%0.37%0.03(n.s)
phosphoinositide biosynthesisGO:0046489112.5%0.37%0.03(n.s)
tRNA aminoacylationGO:0043039112.5%0.46%0.04(n.s)
amino acid activationGO:0043038112.5%0.46%0.04(n.s)
tRNA aminoacylation for protein translationGO:0006418112.5%0.46%0.04(n.s)
phosphoinositide metabolismGO:0030384112.5%0.48%0.04(n.s)
glycerophospholipid biosynthesisGO:0046474112.5%0.53%0.04(n.s)
lipoprotein metabolismGO:0042157112.5%0.56%0.04(n.s)
lipoprotein biosynthesisGO:0042158112.5%0.56%0.04(n.s)
protein lipidationGO:0006497112.5%0.56%0.04(n.s)
telomeric heterochromatin formationGO:0031509112.5%0.67%0.05(n.s)
chromatin silencing at telomereGO:0006348112.5%0.67%0.05(n.s)
glycerophospholipid metabolismGO:0006650112.5%0.68%0.05(n.s)
cell cycle checkpointGO:0000075112.5%0.73%0.06(n.s)
phospholipid biosynthesisGO:0008654112.5%0.81%0.06(n.s)
cellular physiological processGO:00508758100%71.65%0.07(n.s)
cellular processGO:00099878100%72.29%0.07(n.s)
nuclear organization and biogenesisGO:0006997112.5%1.01%0.08(n.s)
tRNA modificationGO:0006400112.5%1.02%0.08(n.s)
response to biotic stimulusGO:0009607112.5%1.08%0.08(n.s)
membrane lipid biosynthesisGO:0046467112.5%1.1%0.08(n.s)
physiological processGO:00075828100%73.68%0.09(n.s)
ER to Golgi transportGO:0006888112.5%1.18%0.09(n.s)
phospholipid metabolismGO:0006644112.5%1.19%0.09(n.s)
negative regulation of gene expression, epigeneticGO:0045814112.5%1.19%0.09(n.s)
chromatin silencingGO:0006342112.5%1.19%0.09(n.s)
gene silencingGO:0016458112.5%1.19%0.09(n.s)
heterochromatin formationGO:0031507112.5%1.19%0.09(n.s)
regulation of gene expression, epigeneticGO:0040029112.5%1.27%0.1(n.s)
chromatin assemblyGO:0031497112.5%1.27%0.1(n.s)
chromatin assembly or disassemblyGO:0006333112.5%1.52%0.12(n.s)
tRNA metabolismGO:0006399112.5%1.6%0.12(n.s)
membrane lipid metabolismGO:0006643112.5%1.61%0.12(n.s)
sexual reproductionGO:0019953112.5%1.63%0.12(n.s)
conjugationGO:0000746112.5%1.63%0.12(n.s)
conjugation with cellular fusionGO:0000747112.5%1.63%0.12(n.s)
negative regulation of transcription, DNA-dependentGO:0045892112.5%1.89%0.14(n.s)
lipid biosynthesisGO:0008610112.5%1.92%0.14(n.s)
negative regulation of transcriptionGO:0016481112.5%1.95%0.15(n.s)
chromatin remodelingGO:0006338112.5%2.01%0.15(n.s)
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045934112.5%2.11%0.16(n.s)
regulation of progression through cell cycleGO:0000074112.5%2.14%0.16(n.s)
Golgi vesicle transportGO:0048193112.5%2.18%0.16(n.s)
biopolymer modificationGO:0043412225%9.25%0.16(n.s)
negative regulation of cellular metabolismGO:0031324112.5%2.29%0.17(n.s)
negative regulation of metabolismGO:0009892112.5%2.4%0.18(n.s)
RNA modificationGO:0009451112.5%2.42%0.18(n.s)
negative regulation of cellular physiological processGO:0051243112.5%2.59%0.19(n.s)
negative regulation of cellular processGO:0048523112.5%2.59%0.19(n.s)
negative regulation of physiological processGO:0043118112.5%2.62%0.19(n.s)
negative regulation of biological processGO:0048519112.5%2.71%0.2(n.s)
chromatin modificationGO:0016568112.5%2.77%0.2(n.s)
amino acid metabolismGO:0006520112.5%2.82%0.2(n.s)
reproductive cellular physiological processGO:0048610112.5%2.93%0.21(n.s)
reproductive physiological processGO:0050876112.5%2.93%0.21(n.s)
amino acid and derivative metabolismGO:0006519112.5%3.05%0.22(n.s)
DNA packagingGO:0006323112.5%3.14%0.23(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325112.5%3.14%0.23(n.s)
cellular lipid metabolismGO:0044255112.5%3.16%0.23(n.s)
lipid metabolismGO:0006629112.5%3.38%0.24(n.s)
amine metabolismGO:0009308112.5%3.38%0.24(n.s)
protein biosynthesisGO:0006412225%12.16%0.25(n.s)
nitrogen compound metabolismGO:0006807112.5%3.66%0.26(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001112.5%3.72%0.26(n.s)
chromosome organization and biogenesisGO:0051276112.5%3.9%0.27(n.s)
reproductionGO:0000003112.5%3.92%0.27(n.s)
macromolecule biosynthesisGO:0009059225%13.04%0.28(n.s)
vesicle-mediated transportGO:0016192112.5%4.34%0.3(n.s)
organic acid metabolismGO:0006082112.5%4.6%0.31(n.s)
carboxylic acid metabolismGO:0019752112.5%4.6%0.31(n.s)
regulation of transcription, DNA-dependentGO:0006355112.5%4.68%0.32(n.s)
biopolymer metabolismGO:0043283337.5%25.06%0.32(n.s)
regulation of transcriptionGO:0045449112.5%4.96%0.33(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219112.5%5.24%0.35(n.s)
organelle organization and biogenesisGO:0006996225%15.69%0.36(n.s)
developmentGO:0007275112.5%5.73%0.38(n.s)
regulation of cellular metabolismGO:0031323112.5%5.98%0.39(n.s)
response to stressGO:0006950112.5%6.09%0.4(n.s)
cell cycleGO:0007049112.5%6.12%0.4(n.s)
cellular biosynthesisGO:0044249225%17.05%0.41(n.s)
regulation of metabolismGO:0019222112.5%6.37%0.41(n.s)
translationGO:0043037112.5%6.47%0.41(n.s)
protein modificationGO:0006464112.5%6.68%0.42(n.s)
transcription, DNA-dependentGO:0006351112.5%6.78%0.43(n.s)
cell organization and biogenesisGO:0016043225%17.98%0.44(n.s)
biosynthesisGO:0009058225%18.28%0.45(n.s)
transcriptionGO:0006350112.5%7.43%0.46(n.s)
RNA metabolismGO:0016070112.5%8.32%0.5(n.s)
response to stimulusGO:0050896112.5%8.41%0.51(n.s)
regulation of cellular physiological processGO:0051244112.5%8.49%0.51(n.s)
regulation of cellular processGO:0050794112.5%8.52%0.51(n.s)
DNA metabolismGO:0006259112.5%8.58%0.51(n.s)
regulation of physiological processGO:0050791112.5%8.77%0.52(n.s)
regulation of biological processGO:0050789112.5%8.97%0.53(n.s)
cellular protein metabolismGO:0044267225%21.7%0.55(n.s)
protein metabolismGO:0019538225%22.06%0.56(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139225%23.17%0.59(n.s)
cellular macromolecule metabolismGO:0044260225%24.52%0.62(n.s)
macromolecule metabolismGO:0043170225%26.04%0.66(n.s)
primary metabolismGO:0044238337.5%48.71%0.84(n.s)
cellular metabolismGO:0044237337.5%52.12%0.88(n.s)
metabolismGO:0008152337.5%52.93%0.89(n.s)
biological_processGO:00081508100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein transporter activityGO:0008565337.5%0.77%2.38E-5(0.04)
asparagine-tRNA ligase activityGO:0004816112.5%0.03%2.48E-3(n.s)
ARF guanyl-nucleotide exchange factor activityGO:0005086112.5%0.09%7.41E-3(n.s)
transporter activityGO:0005215337.5%6.64%0.01(n.s)
ATP bindingGO:0005524112.5%0.22%0.02(n.s)
adenyl nucleotide bindingGO:0030554112.5%0.26%0.02(n.s)
guanyl-nucleotide exchange factor activityGO:0005085112.5%0.4%0.03(n.s)
purine nucleotide bindingGO:0017076112.5%0.5%0.04(n.s)
nucleotide bindingGO:0000166112.5%0.51%0.04(n.s)
ligase activity, forming carbon-oxygen bondsGO:0016875112.5%0.56%0.04(n.s)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876112.5%0.56%0.04(n.s)
tRNA ligase activityGO:0004812112.5%0.56%0.04(n.s)
RNA ligase activityGO:0008452112.5%0.57%0.04(n.s)
ligase activity, forming phosphoric ester bondsGO:0016886112.5%0.62%0.05(n.s)
small GTPase regulator activityGO:0005083112.5%0.88%0.07(n.s)
unfolded protein bindingGO:0051082112.5%0.9%0.07(n.s)
GTPase regulator activityGO:0030695112.5%1.04%0.08(n.s)
protein bindingGO:0005515225%7.39%0.11(n.s)
ligase activityGO:0016874112.5%1.89%0.14(n.s)
bindingGO:0005488337.5%17.35%0.15(n.s)
ATPase activityGO:0016887112.5%2.52%0.19(n.s)
enzyme regulator activityGO:0030234112.5%2.54%0.19(n.s)
nucleoside-triphosphatase activityGO:0017111112.5%3.42%0.24(n.s)
pyrophosphatase activityGO:0016462112.5%3.67%0.26(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817112.5%3.69%0.26(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818112.5%3.69%0.26(n.s)
hydrolase activityGO:0016787112.5%11.45%0.62(n.s)
catalytic activityGO:0003824225%29.21%0.73(n.s)
molecular function unknownGO:0005554225%35.75%0.84(n.s)
molecular_functionGO:00036748100%99.44%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
Sec complex (sensu Eukaryota)GO:0031205337.5%0.11%4.36E-8(7.05E-5)
rough endoplasmic reticulum membraneGO:0030867337.5%0.17%2.05E-7(3.32E-4)
rough endoplasmic reticulumGO:0005791337.5%0.17%2.05E-7(3.32E-4)
Sec62/Sec63 complexGO:0031207225%0.06%8.05E-6(0.01)
nuclear envelope-endoplasmic reticulum networkGO:0042175450%1.95%9.12E-6(0.01)
endomembrane systemGO:0012505450%3.7%1.14E-4(0.18)
endoplasmic reticulum membraneGO:0005789337.5%1.78%2.89E-4(0.47)
endoplasmic reticulumGO:0005783450%5.84%6.64E-4(n.s)
Sec complex-associated translocon complexGO:0031206112.5%0.05%3.71E-3(n.s)
translocon complexGO:0005784112.5%0.08%6.18E-3(n.s)
endoplasmic reticulum lumenGO:0005788112.5%0.09%7.41E-3(n.s)
organelle lumenGO:0043233112.5%0.17%0.01(n.s)
late endosomeGO:0005770112.5%0.2%0.02(n.s)
Golgi vesicleGO:0005798112.5%0.26%0.02(n.s)
membraneGO:0016020450%15.38%0.02(n.s)
organelle membraneGO:0031090337.5%8.58%0.03(n.s)
replication forkGO:0005657112.5%0.6%0.05(n.s)
endosomeGO:0005768112.5%1.07%0.08(n.s)
cytoplasmic vesicleGO:0031410112.5%1.16%0.09(n.s)
cytoplasmic membrane-bound vesicleGO:0016023112.5%1.16%0.09(n.s)
Golgi apparatusGO:0005794112.5%2.01%0.15(n.s)
nuclear chromosomeGO:0000228112.5%2.31%0.17(n.s)
chromosomeGO:0005694112.5%3.16%0.23(n.s)
protein complexGO:0043234337.5%21.07%0.23(n.s)
cytoplasmGO:0005737675%55.64%0.23(n.s)
intracellular membrane-bound organelleGO:0043231675%55.65%0.23(n.s)
membrane-bound organelleGO:0043227675%55.65%0.23(n.s)
cellGO:00056238100%83.5%0.24(n.s)
organelleGO:0043226675%60.56%0.33(n.s)
intracellular organelleGO:0043229675%60.56%0.33(n.s)
intracellularGO:0005622787.5%77.03%0.42(n.s)
cytosolGO:0005829112.5%10.08%0.57(n.s)
intracellular non-membrane-bound organelleGO:0043232112.5%14.3%0.71(n.s)
non-membrane-bound organelleGO:0043228112.5%14.3%0.71(n.s)
mitochondrionGO:0005739112.5%15.78%0.75(n.s)
nucleusGO:0005634112.5%31.01%0.95(n.s)
cellular_componentGO:00055758100%99.61%0.97(n.s)

 

 

cluster_28 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
potassium ion homeostasisGO:0030007120%0.06%3.1E-3(n.s)
monovalent inorganic cation homeostasisGO:0030004120%0.48%0.02(n.s)
metal ion homeostasisGO:0006875120%0.91%0.04(n.s)
aerobic respirationGO:0009060120%1.27%0.06(n.s)
cation homeostasisGO:0030003120%1.35%0.07(n.s)
cellular respirationGO:0045333120%1.35%0.07(n.s)
mitochondrion organization and biogenesisGO:0007005120%1.47%0.07(n.s)
cell ion homeostasisGO:0006873120%1.49%0.07(n.s)
ion homeostasisGO:0050801120%1.55%0.08(n.s)
cell homeostasisGO:0019725120%1.64%0.08(n.s)
homeostasisGO:0042592120%1.73%0.08(n.s)
protein complex assemblyGO:0006461120%2.26%0.11(n.s)
energy derivation by oxidation of organic compoundsGO:0015980120%3.04%0.14(n.s)
generation of precursor metabolites and energyGO:0006091120%3.5%0.16(n.s)
cellular protein metabolismGO:0044267240%21.7%0.3(n.s)
protein metabolismGO:0019538240%22.06%0.31(n.s)
cellular macromolecule metabolismGO:0044260240%24.52%0.36(n.s)
macromolecule metabolismGO:0043170240%26.04%0.39(n.s)
protein biosynthesisGO:0006412120%12.16%0.48(n.s)
macromolecule biosynthesisGO:0009059120%13.04%0.5(n.s)
transportGO:0006810120%14.27%0.54(n.s)
establishment of localizationGO:0051234120%14.39%0.54(n.s)
localizationGO:0051179120%14.82%0.55(n.s)
cellular physiological processGO:0050875480%71.65%0.56(n.s)
organelle organization and biogenesisGO:0006996120%15.69%0.57(n.s)
cellular processGO:0009987480%72.29%0.58(n.s)
physiological processGO:0007582480%73.68%0.61(n.s)
cellular biosynthesisGO:0044249120%17.05%0.61(n.s)
cell organization and biogenesisGO:0016043120%17.98%0.63(n.s)
biosynthesisGO:0009058120%18.28%0.64(n.s)
biological process unknownGO:0000004120%25.64%0.77(n.s)
primary metabolismGO:0044238240%48.71%0.8(n.s)
cellular metabolismGO:0044237240%52.12%0.84(n.s)
metabolismGO:0008152240%52.93%0.85(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
chaperone bindingGO:0051087120%0.17%8.49E-3(n.s)
molecular function unknownGO:0005554360%35.75%0.25(n.s)
transporter activityGO:0005215120%6.64%0.29(n.s)
protein bindingGO:0005515120%7.39%0.32(n.s)
bindingGO:0005488120%17.35%0.61(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial membraneGO:0005740480%3.16%4.72E-6(7.63E-3)
mitochondrionGO:00057395100%15.78%9.72E-5(0.16)
mitochondrial inner membraneGO:0005743360%2.43%1.36E-4(0.22)
inner membraneGO:0019866360%2.43%1.36E-4(0.22)
organelle membraneGO:0031090480%8.58%2.5E-4(0.4)
membraneGO:0016020480%15.38%2.44E-3(n.s)
nucleoidGO:0009295120%0.36%0.02(n.s)
mitochondrial nucleoidGO:0042645120%0.36%0.02(n.s)
cytoplasmGO:00057375100%55.64%0.05(n.s)
intracellular membrane-bound organelleGO:00432315100%55.65%0.05(n.s)
membrane-bound organelleGO:00432275100%55.65%0.05(n.s)
organelleGO:00432265100%60.56%0.08(n.s)
intracellular organelleGO:00432295100%60.56%0.08(n.s)
mitochondrial matrixGO:0005759120%2.52%0.12(n.s)
integral to membraneGO:0016021120%3.55%0.17(n.s)
intrinsic to membraneGO:0031224120%3.61%0.17(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
cellGO:00056235100%83.5%0.41(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_4 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
regulation of cell growthGO:0001558240%0.03%4.8E-7(7.76E-4)
regulation of growthGO:0040008240%0.06%2.88E-6(4.65E-3)
cell growthGO:0016049240%0.06%2.88E-6(4.65E-3)
regulation of developmentGO:0050793240%0.09%7.19E-6(0.01)
regulation of cell sizeGO:0008361240%0.19%3.16E-5(0.05)
regulation of cellular physiological processGO:0051244480%8.49%2.4E-4(0.39)
regulation of cellular processGO:0050794480%8.52%2.43E-4(0.39)
regulation of physiological processGO:0050791480%8.77%2.72E-4(0.44)
regulation of biological processGO:0050789480%8.97%2.98E-4(0.48)
regulation of mitotic recombinationGO:0000019120%0.03%1.55E-3(n.s)
growthGO:0040007240%1.72%2.83E-3(n.s)
actin filament reorganization during cell cycleGO:0030037120%0.06%3.1E-3(n.s)
actin cytoskeleton reorganizationGO:0031532120%0.06%3.1E-3(n.s)
DNA topological changeGO:0006265120%0.08%3.87E-3(n.s)
cell organization and biogenesisGO:0016043480%17.98%4.46E-3(n.s)
cellular morphogenesisGO:0000902240%2.23%4.73E-3(n.s)
morphogenesisGO:0009653240%2.23%4.73E-3(n.s)
signal transductionGO:0007165240%2.59%6.32E-3(n.s)
cell communicationGO:0007154240%3.08%8.89E-3(n.s)
regulation of DNA recombinationGO:0000018120%0.19%9.26E-3(n.s)
Rho protein signal transductionGO:0007266120%0.26%0.01(n.s)
regulation of DNA metabolismGO:0051052120%0.31%0.02(n.s)
G1 phase of mitotic cell cycleGO:0000080120%0.33%0.02(n.s)
G1 phaseGO:0051318120%0.33%0.02(n.s)
mitotic recombinationGO:0006312120%0.39%0.02(n.s)
DNA strand elongationGO:0006271120%0.46%0.02(n.s)
developmentGO:0007275240%5.73%0.03(n.s)
meiotic recombinationGO:0007131120%0.6%0.03(n.s)
cell cycleGO:0007049240%6.12%0.03(n.s)
small GTPase mediated signal transductionGO:0007264120%0.85%0.04(n.s)
meiosis IGO:0007127120%0.85%0.04(n.s)
actin filament organizationGO:0007015120%0.98%0.05(n.s)
endocytosisGO:0006897120%1.07%0.05(n.s)
DNA-dependent DNA replicationGO:0006261120%1.24%0.06(n.s)
interphaseGO:0051325120%1.35%0.07(n.s)
interphase of mitotic cell cycleGO:0051329120%1.35%0.07(n.s)
chromatin assembly or disassemblyGO:0006333120%1.52%0.07(n.s)
actin cytoskeleton organization and biogenesisGO:0030036120%1.55%0.08(n.s)
DNA replicationGO:0006260120%1.6%0.08(n.s)
actin filament-based processGO:0030029120%1.61%0.08(n.s)
intracellular signaling cascadeGO:0007242120%1.66%0.08(n.s)
meiotic cell cycleGO:0051321120%2%0.1(n.s)
meiosisGO:0007126120%2%0.1(n.s)
M phase of meiotic cell cycleGO:0051327120%2%0.1(n.s)
regulation of progression through cell cycleGO:0000074120%2.14%0.1(n.s)
DNA recombinationGO:0006310120%2.91%0.14(n.s)
DNA packagingGO:0006323120%3.14%0.15(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325120%3.14%0.15(n.s)
transportGO:0006810240%14.27%0.15(n.s)
establishment of localizationGO:0051234240%14.39%0.15(n.s)
ribosome biogenesisGO:0007046120%3.3%0.15(n.s)
localizationGO:0051179240%14.82%0.16(n.s)
mitotic cell cycleGO:0000278120%3.59%0.17(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001120%3.72%0.17(n.s)
organelle organization and biogenesisGO:0006996240%15.69%0.18(n.s)
cytoplasm organization and biogenesisGO:0007028120%3.9%0.18(n.s)
chromosome organization and biogenesisGO:0051276120%3.9%0.18(n.s)
ribosome biogenesis and assemblyGO:0042254120%3.9%0.18(n.s)
M phaseGO:0000279120%3.98%0.18(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
vesicle-mediated transportGO:0016192120%4.34%0.2(n.s)
cytoskeleton organization and biogenesisGO:0007010120%4.48%0.2(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219120%5.24%0.24(n.s)
regulation of cellular metabolismGO:0031323120%5.98%0.27(n.s)
regulation of metabolismGO:0019222120%6.37%0.28(n.s)
DNA metabolismGO:0006259120%8.58%0.36(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139120%23.17%0.73(n.s)
biopolymer metabolismGO:0043283120%25.06%0.76(n.s)
primary metabolismGO:0044238120%48.71%0.96(n.s)
cellular metabolismGO:0044237120%52.12%0.97(n.s)
metabolismGO:0008152120%52.93%0.98(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA topoisomerase (ATP-hydrolyzing) activityGO:0003918120%0.02%**
phosphatidylinositol 3-kinase activityGO:0016303120%0.05%2.32E-3(n.s)
phosphoinositide 3-kinase activityGO:0035004120%0.05%2.32E-3(n.s)
DNA topoisomerase activityGO:0003916120%0.08%3.87E-3(n.s)
lipid kinase activityGO:0001727120%0.12%6.18E-3(n.s)
inositol or phosphatidylinositol kinase activityGO:0004428120%0.17%8.49E-3(n.s)
bindingGO:0005488360%17.35%0.04(n.s)
isomerase activityGO:0016853120%0.81%0.04(n.s)
protein bindingGO:0005515240%7.39%0.05(n.s)
phosphotransferase activity, alcohol group as acceptorGO:0016773120%2.62%0.12(n.s)
kinase activityGO:0016301120%3.05%0.14(n.s)
DNA bindingGO:0003677120%3.18%0.15(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772120%5.19%0.23(n.s)
nucleic acid bindingGO:0003676120%9.87%0.41(n.s)
transferase activityGO:0016740120%10.13%0.41(n.s)
catalytic activityGO:0003824240%29.21%0.46(n.s)
molecular function unknownGO:0005554240%35.75%0.59(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
synaptonemal complexGO:0000795120%0.08%3.87E-3(n.s)
peripheral to membrane of membrane fractionGO:0000300120%0.12%6.18E-3(n.s)
endosome membraneGO:0010008120%0.22%0.01(n.s)
Golgi membraneGO:0000139120%0.39%0.02(n.s)
endosomeGO:0005768120%1.07%0.05(n.s)
condensed nuclear chromosomeGO:0000794120%1.12%0.05(n.s)
condensed chromosomeGO:0000793120%1.18%0.06(n.s)
membrane fractionGO:0005624120%1.22%0.06(n.s)
organelle membraneGO:0031090240%8.58%0.06(n.s)
vacuolar membraneGO:0005774120%1.55%0.08(n.s)
cell fractionGO:0000267120%1.72%0.08(n.s)
Golgi apparatusGO:0005794120%2.01%0.1(n.s)
nuclear chromosomeGO:0000228120%2.31%0.11(n.s)
vacuoleGO:0005773120%2.97%0.14(n.s)
chromosomeGO:0005694120%3.16%0.15(n.s)
plasma membraneGO:0005886120%3.67%0.17(n.s)
membraneGO:0016020240%15.38%0.17(n.s)
endomembrane systemGO:0012505120%3.7%0.17(n.s)
cytoplasmGO:0005737480%55.64%0.27(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
cellGO:00056235100%83.5%0.41(n.s)
intracellular non-membrane-bound organelleGO:0043232120%14.3%0.54(n.s)
non-membrane-bound organelleGO:0043228120%14.3%0.54(n.s)
mitochondrionGO:0005739120%15.78%0.58(n.s)
intracellular membrane-bound organelleGO:0043231360%55.65%0.61(n.s)
membrane-bound organelleGO:0043227360%55.65%0.61(n.s)
organelleGO:0043226360%60.56%0.69(n.s)
intracellular organelleGO:0043229360%60.56%0.69(n.s)
nucleusGO:0005634120%31.01%0.84(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_8 (n = 10)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
branched chain family amino acid biosynthesisGO:0009082770%0.2%2.22E-18(3.59E-15)
branched chain family amino acid metabolismGO:0009081770%0.25%1.48E-17(2.39E-14)
amino acid biosynthesisGO:0008652990%1.53%3.2E-16(5.17E-13)
nitrogen compound biosynthesisGO:0044271990%1.67%7.22E-16(1.17E-12)
amine biosynthesisGO:0009309990%1.67%7.22E-16(1.17E-12)
amino acid metabolismGO:0006520990%2.82%9.03E-14(1.46E-10)
amino acid and derivative metabolismGO:0006519990%3.05%1.87E-13(3.02E-10)
amine metabolismGO:0009308990%3.38%4.71E-13(7.62E-10)
nitrogen compound metabolismGO:0006807990%3.66%9.73E-13(1.57E-9)
organic acid metabolismGO:0006082990%4.6%7.88E-12(1.27E-8)
carboxylic acid metabolismGO:0019752990%4.6%7.88E-12(1.27E-8)
cellular biosynthesisGO:004424910100%17.05%2.01E-8(3.25E-5)
biosynthesisGO:000905810100%18.28%4.03E-8(6.52E-5)
lysine biosynthesis via aminoadipic acidGO:0019878220%0.12%6.02E-5(0.1)
lysine biosynthesisGO:0009085220%0.14%7.73E-5(0.12)
lysine metabolismGO:0006553220%0.14%7.73E-5(0.12)
aspartate family amino acid biosynthesisGO:0009067220%0.28%3.26E-4(0.53)
amino acid catabolismGO:0009063220%0.43%7.99E-4(n.s)
amine catabolismGO:0009310220%0.48%9.8E-4(n.s)
nitrogen compound catabolismGO:0044270220%0.48%9.8E-4(n.s)
cellular metabolismGO:004423710100%52.12%1.47E-3(n.s)
metabolismGO:000815210100%52.93%1.71E-3(n.s)
aspartate family amino acid metabolismGO:0009066220%0.7%2.06E-3(n.s)
leucine biosynthesisGO:0009098110%0.08%7.72E-3(n.s)
primary metabolismGO:0044238990%48.71%8.64E-3(n.s)
leucine metabolismGO:0006551110%0.11%0.01(n.s)
pantothenate biosynthesisGO:0015940110%0.12%0.01(n.s)
pantothenate metabolismGO:0015939110%0.12%0.01(n.s)
cellular physiological processGO:005087510100%71.65%0.04(n.s)
cellular processGO:000998710100%72.29%0.04(n.s)
mitochondrial genome maintenanceGO:0000002110%0.42%0.04(n.s)
physiological processGO:000758210100%73.68%0.05(n.s)
group transfer coenzyme metabolismGO:0006752110%0.68%0.07(n.s)
coenzyme biosynthesisGO:0009108110%0.87%0.08(n.s)
cofactor biosynthesisGO:0051188110%1.08%0.1(n.s)
cellular catabolismGO:0044248220%5.84%0.11(n.s)
catabolismGO:0009056220%6.16%0.12(n.s)
mitochondrion organization and biogenesisGO:0007005110%1.47%0.14(n.s)
coenzyme metabolismGO:0006732110%1.81%0.17(n.s)
cofactor metabolismGO:0051186110%2.26%0.2(n.s)
organelle organization and biogenesisGO:0006996110%15.69%0.82(n.s)
cell organization and biogenesisGO:0016043110%17.98%0.86(n.s)
biological_processGO:000815010100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
acetolactate synthase activityGO:0003984220%0.03%2.16E-6(3.49E-3)
branched-chain-amino-acid transaminase activityGO:0004084220%0.03%2.16E-6(3.49E-3)
catalytic activityGO:000382410100%29.21%4.45E-6(7.19E-3)
transferase activityGO:0016740770%10.13%9.69E-6(0.02)
transferase activity, transferring aldehyde or ketonic groupsGO:0016744220%0.09%3.23E-5(0.05)
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transferGO:0046912220%0.15%9.65E-5(0.16)
transaminase activityGO:0008483220%0.25%2.56E-4(0.41)
transferase activity, transferring nitrogenous groupsGO:0016769220%0.25%2.56E-4(0.41)
hydro-lyase activityGO:0016836220%0.43%7.99E-4(n.s)
carbon-oxygen lyase activityGO:0016835220%0.56%1.32E-3(n.s)
ketol-acid reductoisomerase activityGO:0004455110%0.02%**
homoaconitate hydratase activityGO:0004409110%0.02%**
3-methyl-2-oxobutanoate hydroxymethyltransferase activityGO:0003864110%0.02%**
dihydroxy-acid dehydratase activityGO:0004160110%0.02%**
FAD bindingGO:0050660110%0.02%**
coenzyme bindingGO:0050662110%0.03%3.1E-3(n.s)
homocitrate synthase activityGO:0004410110%0.03%3.1E-3(n.s)
2-isopropylmalate synthase activityGO:0003852110%0.03%3.1E-3(n.s)
cofactor bindingGO:0048037110%0.05%4.64E-3(n.s)
lyase activityGO:0016829220%1.27%6.71E-3(n.s)
hydroxymethyl-, formyl- and related transferase activityGO:0016742110%0.08%7.72E-3(n.s)
transferase activity, transferring acyl groupsGO:0016746220%1.43%8.39E-3(n.s)
glycine hydroxymethyltransferase activityGO:0004372110%0.11%0.01(n.s)
adenyl nucleotide bindingGO:0030554110%0.26%0.03(n.s)
purine nucleotide bindingGO:0017076110%0.5%0.05(n.s)
nucleotide bindingGO:0000166110%0.51%0.05(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616110%1.07%0.1(n.s)
methyltransferase activityGO:0008168110%1.1%0.1(n.s)
transferase activity, transferring one-carbon groupsGO:0016741110%1.13%0.11(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614110%1.18%0.11(n.s)
enzyme regulator activityGO:0030234110%2.54%0.23(n.s)
oxidoreductase activityGO:0016491110%3.73%0.32(n.s)
bindingGO:0005488110%17.35%0.85(n.s)
molecular_functionGO:000367410100%99.44%0.95(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
acetolactate synthase complexGO:0005948220%0.03%2.16E-6(3.49E-3)
mitochondrionGO:0005739880%15.78%1.25E-5(0.02)
nucleoidGO:0009295220%0.36%5.37E-4(0.87)
mitochondrial nucleoidGO:0042645220%0.36%5.37E-4(0.87)
unlocalized protein complexGO:0005941220%0.57%1.4E-3(n.s)
mitochondrial matrixGO:0005759330%2.52%1.66E-3(n.s)
intracellular membrane-bound organelleGO:004323110100%55.65%2.83E-3(n.s)
membrane-bound organelleGO:004322710100%55.65%2.83E-3(n.s)
organelleGO:004322610100%60.56%6.61E-3(n.s)
intracellular organelleGO:004322910100%60.56%6.61E-3(n.s)
cytoplasmGO:0005737990%55.64%0.03(n.s)
intracellularGO:000562210100%77.03%0.07(n.s)
peroxisomeGO:0005777110%0.87%0.08(n.s)
microbodyGO:0042579110%0.87%0.08(n.s)
cellGO:000562310100%83.5%0.16(n.s)
protein complexGO:0043234220%21.07%0.66(n.s)
nucleusGO:0005634220%31.01%0.87(n.s)
cellular_componentGO:000557510100%99.61%0.96(n.s)

 

 

cluster_58 (n = 16)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
vacuolar acidificationGO:00070351593.75%0.34%2.57E-39(4.15E-36)
hydrogen ion homeostasisGO:00306411593.75%0.34%2.57E-39(4.15E-36)
regulation of cellular pHGO:00514531593.75%0.34%2.57E-39(4.15E-36)
pH reductionGO:00458511593.75%0.34%2.57E-39(4.15E-36)
cellular pH reductionGO:00514521593.75%0.34%2.57E-39(4.15E-36)
regulation of pHGO:00068851593.75%0.4%1.16E-37(1.88E-34)
monovalent inorganic cation homeostasisGO:00300041593.75%0.48%4.52E-36(7.3E-33)
vacuolar transportGO:00070341593.75%0.73%1.13E-32(1.82E-29)
cation homeostasisGO:00300031593.75%1.35%3.93E-28(6.34E-25)
cell ion homeostasisGO:00068731593.75%1.49%1.95E-27(3.15E-24)
ion homeostasisGO:00508011593.75%1.55%3.77E-27(6.09E-24)
cell homeostasisGO:00197251593.75%1.64%9.64E-27(1.56E-23)
homeostasisGO:00425921593.75%1.73%2.33E-26(3.77E-23)
intracellular transportGO:00469071593.75%7.53%1.72E-16(2.78E-13)
transportGO:00068101593.75%14.27%2.6E-12(4.2E-9)
establishment of localizationGO:00512341593.75%14.39%2.96E-12(4.78E-9)
localizationGO:00511791593.75%14.82%4.61E-12(7.45E-9)
early endosome to late endosome transportGO:004502216.25%0.02%**
regulation of protein complex assemblyGO:004325416.25%0.03%4.95E-3(n.s)
polyphosphate metabolismGO:000679716.25%0.05%7.42E-3(n.s)
intron homingGO:000631416.25%0.08%0.01(n.s)
copper ion homeostasisGO:000687816.25%0.11%0.02(n.s)
cellular physiological processGO:00508751593.75%71.65%0.04(n.s)
cellular processGO:00099871593.75%72.29%0.04(n.s)
physiological processGO:00075821593.75%73.68%0.05(n.s)
hydrogen transportGO:000681816.25%0.37%0.06(n.s)
proton transportGO:001599216.25%0.37%0.06(n.s)
glycogen metabolismGO:000597716.25%0.4%0.06(n.s)
iron ion homeostasisGO:000687916.25%0.45%0.07(n.s)
monovalent inorganic cation transportGO:001567216.25%0.45%0.07(n.s)
energy reserve metabolismGO:000611216.25%0.5%0.08(n.s)
endosome transportGO:001619716.25%0.56%0.09(n.s)
endosome organization and biogenesisGO:000703216.25%0.56%0.09(n.s)
vacuole organization and biogenesisGO:000703316.25%0.59%0.09(n.s)
glucan metabolismGO:000607316.25%0.59%0.09(n.s)
regulation of protein metabolismGO:005124616.25%0.67%0.1(n.s)
transition metal ion homeostasisGO:004691616.25%0.73%0.11(n.s)
polysaccharide metabolismGO:000597616.25%0.81%0.12(n.s)
cellular polysaccharide metabolismGO:004426416.25%0.81%0.12(n.s)
di-, tri-valent inorganic cation homeostasisGO:003000516.25%0.81%0.12(n.s)
metal ion homeostasisGO:000687516.25%0.91%0.14(n.s)
protein-vacuolar targetingGO:000662316.25%0.93%0.14(n.s)
vesicle-mediated transportGO:0016192212.5%4.34%0.15(n.s)
endocytosisGO:000689716.25%1.07%0.16(n.s)
cation transportGO:000681216.25%1.36%0.2(n.s)
ion transportGO:000681116.25%1.64%0.23(n.s)
DNA transpositionGO:000631316.25%1.67%0.24(n.s)
protein complex assemblyGO:000646116.25%2.26%0.31(n.s)
phosphate metabolismGO:000679616.25%2.91%0.38(n.s)
phosphorus metabolismGO:000679316.25%2.91%0.38(n.s)
DNA recombinationGO:000631016.25%2.91%0.38(n.s)
energy derivation by oxidation of organic compoundsGO:001598016.25%3.04%0.39(n.s)
cellular carbohydrate metabolismGO:004426216.25%3.08%0.39(n.s)
carbohydrate metabolismGO:000597516.25%3.38%0.42(n.s)
protein targetingGO:000660516.25%3.42%0.43(n.s)
generation of precursor metabolites and energyGO:000609116.25%3.5%0.43(n.s)
intracellular protein transportGO:000688616.25%3.7%0.45(n.s)
protein transportGO:001503116.25%3.79%0.46(n.s)
establishment of protein localizationGO:004518416.25%3.95%0.48(n.s)
protein localizationGO:000810416.25%4.37%0.51(n.s)
regulation of metabolismGO:001922216.25%6.37%0.65(n.s)
organelle organization and biogenesisGO:0006996212.5%15.69%0.74(n.s)
DNA metabolismGO:000625916.25%8.58%0.76(n.s)
regulation of physiological processGO:005079116.25%8.77%0.77(n.s)
regulation of biological processGO:005078916.25%8.97%0.78(n.s)
cell organization and biogenesisGO:0016043212.5%17.98%0.81(n.s)
macromolecule metabolismGO:0043170318.75%26.04%0.83(n.s)
protein metabolismGO:0019538212.5%22.06%0.9(n.s)
cellular macromolecule metabolismGO:0044260212.5%24.52%0.93(n.s)
biopolymer metabolismGO:0043283212.5%25.06%0.94(n.s)
cellular protein metabolismGO:004426716.25%21.7%0.98(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613916.25%23.17%0.99(n.s)
cellular metabolismGO:0044237425%52.12%0.99(n.s)
metabolismGO:0008152425%52.93%0.99(n.s)
primary metabolismGO:0044238318.75%48.71%1(n.s)
biological_processGO:00081501593.75%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrogen-transporting ATPase activity, rotational mechanismGO:00469611381.25%0.2%1.04E-37(1.69E-34)
cation-transporting ATPase activityGO:00198291381.25%0.26%2.48E-34(4E-31)
P-P-bond-hydrolysis-driven transporter activityGO:00154051381.25%0.45%7.03E-30(1.14E-26)
ATPase activity, coupled to transmembrane movement of ionsGO:00426251381.25%0.46%1.24E-29(2E-26)
hydrogen ion transporter activityGO:00150781487.5%0.84%1.56E-28(2.52E-25)
monovalent inorganic cation transporter activityGO:00150771487.5%0.88%3.69E-28(5.96E-25)
primary active transporter activityGO:00153991381.25%0.77%3.64E-26(5.88E-23)
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesGO:00168201381.25%0.87%1.93E-25(3.13E-22)
ATPase activity, coupled to transmembrane movement of substancesGO:00426261381.25%0.87%1.93E-25(3.13E-22)
cation transporter activityGO:00083241487.5%1.89%4.02E-23(6.5E-20)
ion transporter activityGO:00150751487.5%2.21%4.16E-22(6.72E-19)
ATPase activity, coupledGO:00426231381.25%1.58%9.38E-22(1.52E-18)
carrier activityGO:00053861381.25%1.64%1.59E-21(2.58E-18)
ATPase activityGO:00168871381.25%2.52%5.5E-19(8.89E-16)
nucleoside-triphosphatase activityGO:00171111381.25%3.42%3.2E-17(5.17E-14)
pyrophosphatase activityGO:00164621381.25%3.67%8.08E-17(1.31E-13)
hydrolase activity, acting on acid anhydridesGO:00168171381.25%3.69%8.54E-17(1.38E-13)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:00168181381.25%3.69%8.54E-17(1.38E-13)
transporter activityGO:00052151487.5%6.64%2.84E-15(4.59E-12)
hydrolase activityGO:00167871381.25%11.45%2.12E-10(3.43E-7)
catalytic activityGO:00038241381.25%29.21%2.39E-5(0.04)
endodeoxyribonuclease activityGO:000452016.25%0.28%0.04(n.s)
deoxyribonuclease activityGO:000453616.25%0.31%0.05(n.s)
endonuclease activityGO:000451916.25%0.88%0.13(n.s)
nuclease activityGO:000451816.25%2.15%0.29(n.s)
hydrolase activity, acting on ester bondsGO:001678816.25%4.12%0.49(n.s)
molecular_functionGO:000367416100%99.44%0.91(n.s)
molecular function unknownGO:0005554212.5%35.75%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrogen-translocating V-type ATPase complexGO:00164711487.5%0.23%7.28E-40(1.18E-36)
vacuolar membraneGO:00057741487.5%1.55%2.09E-24(3.38E-21)
hydrogen-transporting ATPase V1 domainGO:0000221850%0.12%1.73E-22(2.79E-19)
vacuoleGO:00057731487.5%2.97%3.01E-20(4.86E-17)
hydrogen-transporting ATPase V0 domainGO:0000220637.5%0.11%5.58E-16(9.02E-13)
organelle membraneGO:00310901487.5%8.58%1.03E-13(1.66E-10)
membraneGO:00160201593.75%15.38%8E-12(1.29E-8)
protein complexGO:004323416100%21.07%1.4E-11(2.27E-8)
vacuolar membrane (sensu Fungi)GO:0000329637.5%0.96%4.55E-9(7.36E-6)
vacuole (sensu Fungi)GO:0000324637.5%2.23%7.39E-7(1.19E-3)
storage vacuoleGO:0000322637.5%2.23%7.39E-7(1.19E-3)
lytic vacuoleGO:0000323637.5%2.23%7.39E-7(1.19E-3)
RAVE complexGO:0043291212.5%0.05%1.73E-5(0.03)
cytoplasmGO:000573716100%55.64%8.31E-5(0.13)
intracellular membrane-bound organelleGO:00432311487.5%55.65%7.56E-3(n.s)
membrane-bound organelleGO:00432271487.5%55.65%7.56E-3(n.s)
intracellularGO:000562216100%77.03%0.02(n.s)
integral to membraneGO:0016021318.75%3.55%0.02(n.s)
intrinsic to membraneGO:0031224318.75%3.61%0.02(n.s)
organelleGO:00432261487.5%60.56%0.02(n.s)
intracellular organelleGO:00432291487.5%60.56%0.02(n.s)
cellGO:000562316100%83.5%0.06(n.s)
extrinsic to membraneGO:001989816.25%0.48%0.07(n.s)
endosomeGO:000576816.25%1.07%0.16(n.s)
Golgi apparatusGO:000579416.25%2.01%0.28(n.s)
cellular_componentGO:000557516100%99.61%0.94(n.s)

 

 

cluster_54 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
beta-1,3 glucan biosynthesisGO:0006075240%0.06%2.88E-6(4.65E-3)
beta-1,3 glucan metabolismGO:0006074240%0.06%2.88E-6(4.65E-3)
beta-glucan biosynthesisGO:0051274240%0.12%1.34E-5(0.02)
beta-glucan metabolismGO:0051273240%0.14%1.72E-5(0.03)
cell wall polysaccharide biosynthesis (sensu Fungi)GO:0051278240%0.23%5.02E-5(0.08)
glucan biosynthesisGO:0009250240%0.25%5.73E-5(0.09)
cell wall biosynthesis (sensu Fungi)GO:0009272240%0.31%9.07E-5(0.15)
cell wall biosynthesisGO:0042546240%0.31%9.07E-5(0.15)
cell wall organization and biogenesis (sensu Fungi)GO:0031505240%0.31%9.07E-5(0.15)
cell wall organization and biogenesisGO:0007047360%2.17%9.67E-5(0.16)
external encapsulating structure organization and biogenesisGO:0045229360%2.17%9.67E-5(0.16)
biopolymer biosynthesisGO:0043284240%0.39%1.43E-4(0.23)
polysaccharide biosynthesisGO:0000271240%0.39%1.43E-4(0.23)
glucan metabolismGO:0006073240%0.59%3.34E-4(0.54)
polysaccharide metabolismGO:0005976240%0.81%6.27E-4(n.s)
cellular polysaccharide metabolismGO:0044264240%0.81%6.27E-4(n.s)
photoreactive repairGO:0000719120%0.02%**
pyrimidine dimer repairGO:0006290120%0.02%**
carbohydrate biosynthesisGO:0016051240%0.91%8.07E-4(n.s)
fatty acid elongationGO:0030497120%0.06%3.1E-3(n.s)
cellular carbohydrate metabolismGO:0044262240%3.08%8.89E-3(n.s)
fatty acid biosynthesisGO:0006633120%0.19%9.26E-3(n.s)
carbohydrate metabolismGO:0005975240%3.38%0.01(n.s)
organic acid biosynthesisGO:0016053120%0.26%0.01(n.s)
carboxylic acid biosynthesisGO:0046394120%0.26%0.01(n.s)
sphingolipid biosynthesisGO:0030148120%0.29%0.01(n.s)
vesicle-mediated transportGO:0016192240%4.34%0.02(n.s)
sphingolipid metabolismGO:0006665120%0.45%0.02(n.s)
fatty acid metabolismGO:0006631120%0.67%0.03(n.s)
cellular biosynthesisGO:0044249360%17.05%0.04(n.s)
cell organization and biogenesisGO:0016043360%17.98%0.04(n.s)
biosynthesisGO:0009058360%18.28%0.05(n.s)
endocytosisGO:0006897120%1.07%0.05(n.s)
membrane lipid biosynthesisGO:0046467120%1.1%0.05(n.s)
filamentous growthGO:0030447120%1.32%0.06(n.s)
membrane lipid metabolismGO:0006643120%1.61%0.08(n.s)
growthGO:0040007120%1.72%0.08(n.s)
lipid biosynthesisGO:0008610120%1.92%0.09(n.s)
biopolymer metabolismGO:0043283360%25.06%0.1(n.s)
DNA repairGO:0006281120%2.32%0.11(n.s)
response to DNA damage stimulusGO:0006974120%2.73%0.13(n.s)
macromolecule biosynthesisGO:0009059240%13.04%0.13(n.s)
response to endogenous stimulusGO:0009719120%2.82%0.13(n.s)
cellular lipid metabolismGO:0044255120%3.16%0.15(n.s)
transportGO:0006810240%14.27%0.15(n.s)
establishment of localizationGO:0051234240%14.39%0.15(n.s)
lipid metabolismGO:0006629120%3.38%0.16(n.s)
localizationGO:0051179240%14.82%0.16(n.s)
primary metabolismGO:0044238480%48.71%0.17(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
organic acid metabolismGO:0006082120%4.6%0.21(n.s)
carboxylic acid metabolismGO:0019752120%4.6%0.21(n.s)
cellular metabolismGO:0044237480%52.12%0.22(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
metabolismGO:0008152480%52.93%0.23(n.s)
response to stressGO:0006950120%6.09%0.27(n.s)
response to stimulusGO:0050896120%8.41%0.36(n.s)
cellular macromolecule metabolismGO:0044260240%24.52%0.36(n.s)
DNA metabolismGO:0006259120%8.58%0.36(n.s)
macromolecule metabolismGO:0043170240%26.04%0.39(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139120%23.17%0.73(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
1,3-beta-glucan synthase activityGO:0003843240%0.05%1.44E-6(2.33E-3)
UDP-glucosyltransferase activityGO:0035251240%0.19%3.16E-5(0.05)
glucosyltransferase activityGO:0046527240%0.22%4.35E-5(0.07)
UDP-glycosyltransferase activityGO:0008194240%0.26%6.5E-5(0.1)
transferase activityGO:0016740480%10.13%4.8E-4(0.78)
DNA photolyase activityGO:0003913120%0.02%**
deoxyribodipyrimidine photo-lyase activityGO:0003904120%0.02%**
transferase activity, transferring hexosyl groupsGO:0016758240%1.12%1.2E-3(n.s)
transferase activity, transferring glycosyl groupsGO:0016757240%1.41%1.91E-3(n.s)
catalytic activityGO:00038245100%29.21%2.12E-3(n.s)
fatty acid elongase activityGO:0009922120%0.05%2.32E-3(n.s)
glucanosyltransferase activityGO:0042123120%0.08%3.87E-3(n.s)
1,3-beta-glucanosyltransferase activityGO:0042124120%0.08%3.87E-3(n.s)
fatty-acid synthase activityGO:0004312120%0.12%6.18E-3(n.s)
carbon-carbon lyase activityGO:0016830120%0.43%0.02(n.s)
acyltransferase activityGO:0008415120%1.19%0.06(n.s)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747120%1.19%0.06(n.s)
lyase activityGO:0016829120%1.27%0.06(n.s)
transferase activity, transferring acyl groupsGO:0016746120%1.43%0.07(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
1,3-beta-glucan synthase complexGO:0000148240%0.05%1.44E-6(2.33E-3)
actin capGO:0030478240%0.23%5.02E-5(0.08)
plasma membraneGO:0005886360%3.67%4.62E-4(0.75)
cortical cytoskeletonGO:0030863240%0.84%6.76E-4(n.s)
cortical actin cytoskeletonGO:0030864240%0.84%6.76E-4(n.s)
actin cytoskeletonGO:0015629240%1.38%1.83E-3(n.s)
cell cortexGO:0005938240%1.52%2.21E-3(n.s)
membraneGO:0016020480%15.38%2.44E-3(n.s)
cytoskeletonGO:0005856240%2.93%8.04E-3(n.s)
prospore membraneGO:0005628120%0.25%0.01(n.s)
prosporeGO:0042764120%0.25%0.01(n.s)
immature sporeGO:0042763120%0.25%0.01(n.s)
actin cortical patchGO:0030479120%0.62%0.03(n.s)
cytoplasmGO:00057375100%55.64%0.05(n.s)
organelleGO:00432265100%60.56%0.08(n.s)
intracellular organelleGO:00432295100%60.56%0.08(n.s)
external encapsulating structureGO:0030312120%1.72%0.08(n.s)
cell wallGO:0005618120%1.72%0.08(n.s)
cell wall (sensu Fungi)GO:0009277120%1.72%0.08(n.s)
endoplasmic reticulum membraneGO:0005789120%1.78%0.09(n.s)
nuclear envelope-endoplasmic reticulum networkGO:0042175120%1.95%0.09(n.s)
intracellular non-membrane-bound organelleGO:0043232240%14.3%0.15(n.s)
non-membrane-bound organelleGO:0043228240%14.3%0.15(n.s)
endomembrane systemGO:0012505120%3.7%0.17(n.s)
mitochondrionGO:0005739240%15.78%0.18(n.s)
endoplasmic reticulumGO:0005783120%5.84%0.26(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
protein complexGO:0043234240%21.07%0.28(n.s)
organelle membraneGO:0031090120%8.58%0.36(n.s)
cellGO:00056235100%83.5%0.41(n.s)
intracellular membrane-bound organelleGO:0043231360%55.65%0.61(n.s)
membrane-bound organelleGO:0043227360%55.65%0.61(n.s)
nucleusGO:0005634120%31.01%0.84(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_51 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
arginine biosynthesisGO:0006526480%0.15%1.45E-11(2.34E-8)
urea cycle intermediate metabolismGO:0000051480%0.23%9.42E-11(1.52E-7)
arginine metabolismGO:0006525480%0.23%9.42E-11(1.52E-7)
glutamine family amino acid biosynthesisGO:0009084480%0.37%7.33E-10(1.18E-6)
ornithine biosynthesisGO:0006592360%0.06%8.92E-10(1.44E-6)
nonprotein amino acid biosynthesisGO:0019795360%0.09%4.46E-9(7.2E-6)
ornithine metabolismGO:0006591360%0.09%4.46E-9(7.2E-6)
glutamine family amino acid metabolismGO:0009064480%0.67%8.49E-9(1.37E-5)
nonprotein amino acid metabolismGO:0019794360%0.14%1.87E-8(3.02E-5)
amino acid biosynthesisGO:0008652480%1.53%2.57E-7(4.16E-4)
nitrogen compound biosynthesisGO:0044271480%1.67%3.66E-7(5.91E-4)
amine biosynthesisGO:0009309480%1.67%3.66E-7(5.91E-4)
amino acid metabolismGO:0006520480%2.82%2.99E-6(4.83E-3)
amino acid and derivative metabolismGO:0006519480%3.05%4.11E-6(6.64E-3)
amine metabolismGO:0009308480%3.38%6.16E-6(9.96E-3)
nitrogen compound metabolismGO:0006807480%3.66%8.46E-6(0.01)
organic acid metabolismGO:0006082480%4.6%2.12E-5(0.03)
carboxylic acid metabolismGO:0019752480%4.6%2.12E-5(0.03)
mitochondrial ornithine transportGO:0000066120%0.02%**
L-ornithine transportGO:0015822120%0.02%**
cellular biosynthesisGO:0044249480%17.05%3.64E-3(n.s)
L-amino acid transportGO:0015807120%0.09%4.64E-3(n.s)
biosynthesisGO:0009058480%18.28%4.75E-3(n.s)
mitochondrial transportGO:0006839120%0.17%8.49E-3(n.s)
amino acid transportGO:0006865120%0.57%0.03(n.s)
amine transportGO:0015837120%0.74%0.04(n.s)
carboxylic acid transportGO:0046942120%0.77%0.04(n.s)
organic acid transportGO:0015849120%0.79%0.04(n.s)
external encapsulating structure organization and biogenesisGO:0045229120%2.17%0.1(n.s)
cell wall organization and biogenesisGO:0007047120%2.17%0.1(n.s)
primary metabolismGO:0044238480%48.71%0.17(n.s)
cellular metabolismGO:0044237480%52.12%0.22(n.s)
metabolismGO:0008152480%52.93%0.23(n.s)
intracellular transportGO:0046907120%7.53%0.32(n.s)
transportGO:0006810120%14.27%0.54(n.s)
establishment of localizationGO:0051234120%14.39%0.54(n.s)
localizationGO:0051179120%14.82%0.55(n.s)
cellular physiological processGO:0050875480%71.65%0.56(n.s)
cellular processGO:0009987480%72.29%0.58(n.s)
physiological processGO:0007582480%73.68%0.61(n.s)
cell organization and biogenesisGO:0016043120%17.98%0.63(n.s)
biological_processGO:0008150480%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
amino-acid N-acetyltransferase activityGO:0004042240%0.06%2.88E-6(4.65E-3)
N-acetyltransferase activityGO:0008080240%0.53%2.67E-4(0.43)
N-acyltransferase activityGO:0016410240%0.59%3.34E-4(0.54)
acetyltransferase activityGO:0016407240%0.71%4.9E-4(0.79)
acetylornithine transaminase activityGO:0003992120%0.02%**
L-ornithine transporter activityGO:0000064120%0.02%**
glutamate N-acetyltransferase activityGO:0004358120%0.02%**
acyltransferase activityGO:0008415240%1.19%1.37E-3(n.s)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747240%1.19%1.37E-3(n.s)
transferase activity, transferring acyl groupsGO:0016746240%1.43%1.95E-3(n.s)
transferase activityGO:0016740360%10.13%8.85E-3(n.s)
L-amino acid transporter activityGO:0015179120%0.19%9.26E-3(n.s)
transferase activity, transferring nitrogenous groupsGO:0016769120%0.25%0.01(n.s)
transaminase activityGO:0008483120%0.25%0.01(n.s)
amino acid transporter activityGO:0015171120%0.5%0.02(n.s)
amine transporter activityGO:0005275120%0.64%0.03(n.s)
carboxylic acid transporter activityGO:0046943120%0.74%0.04(n.s)
organic acid transporter activityGO:0005342120%0.79%0.04(n.s)
catalytic activityGO:0003824360%29.21%0.15(n.s)
transporter activityGO:0005215120%6.64%0.29(n.s)
molecular_functionGO:0003674480%99.44%1(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial matrixGO:0005759360%2.52%1.52E-4(0.25)
mitochondrionGO:0005739480%15.78%2.7E-3(n.s)
mitochondrial membraneGO:0005740120%3.16%0.15(n.s)
cytoplasmGO:0005737480%55.64%0.27(n.s)
intracellular membrane-bound organelleGO:0043231480%55.65%0.27(n.s)
membrane-bound organelleGO:0043227480%55.65%0.27(n.s)
organelleGO:0043226480%60.56%0.35(n.s)
intracellular organelleGO:0043229480%60.56%0.35(n.s)
organelle membraneGO:0031090120%8.58%0.36(n.s)
membraneGO:0016020120%15.38%0.57(n.s)
intracellularGO:0005622480%77.03%0.68(n.s)
cellGO:0005623480%83.5%0.81(n.s)
cellular_componentGO:0005575480%99.61%1(n.s)

 

 

cluster_115 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
L-glutamate transportGO:0015813120%0.02%**
acidic amino acid transportGO:0015800120%0.02%**
L-aspartate transportGO:0015810120%0.02%**
transportGO:0006810480%14.27%1.83E-3(n.s)
establishment of localizationGO:0051234480%14.39%1.89E-3(n.s)
localizationGO:0051179480%14.82%2.12E-3(n.s)
L-amino acid transportGO:0015807120%0.09%4.64E-3(n.s)
amino acid transportGO:0006865120%0.57%0.03(n.s)
fatty acid metabolismGO:0006631120%0.67%0.03(n.s)
amine transportGO:0015837120%0.74%0.04(n.s)
carboxylic acid transportGO:0046942120%0.77%0.04(n.s)
organic acid transportGO:0015849120%0.79%0.04(n.s)
cellular lipid metabolismGO:0044255120%3.16%0.15(n.s)
lipid metabolismGO:0006629120%3.38%0.16(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
organic acid metabolismGO:0006082120%4.6%0.21(n.s)
carboxylic acid metabolismGO:0019752120%4.6%0.21(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
primary metabolismGO:0044238120%48.71%0.96(n.s)
cellular metabolismGO:0044237120%52.12%0.97(n.s)
metabolismGO:0008152120%52.93%0.98(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transporter activityGO:00052155100%6.64%1.27E-6(2.05E-3)
carnitine:acyl carnitine antiporter activityGO:0005476120%0.02%**
acidic amino acid transporter activityGO:0015172120%0.02%**
L-aspartate transporter activityGO:0015183120%0.02%**
L-glutamate transporter activityGO:0005313120%0.02%**
calcium ion bindingGO:0005509120%0.06%3.1E-3(n.s)
solute:solute antiporter activityGO:0015300120%0.08%3.87E-3(n.s)
antiporter activityGO:0015297120%0.14%6.95E-3(n.s)
cation bindingGO:0043169120%0.19%9.26E-3(n.s)
L-amino acid transporter activityGO:0015179120%0.19%9.26E-3(n.s)
metal ion bindingGO:0046872120%0.25%0.01(n.s)
ion bindingGO:0043167120%0.25%0.01(n.s)
amino acid transporter activityGO:0015171120%0.5%0.02(n.s)
porter activityGO:0015291120%0.59%0.03(n.s)
electrochemical potential-driven transporter activityGO:0015290120%0.59%0.03(n.s)
amine transporter activityGO:0005275120%0.64%0.03(n.s)
carboxylic acid transporter activityGO:0046943120%0.74%0.04(n.s)
organic acid transporter activityGO:0005342120%0.79%0.04(n.s)
carrier activityGO:0005386120%1.64%0.08(n.s)
bindingGO:0005488120%17.35%0.61(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:00057435100%2.43%7.99E-9(1.29E-5)
inner membraneGO:00198665100%2.43%7.99E-9(1.29E-5)
mitochondrial membraneGO:00057405100%3.16%3E-8(4.85E-5)
organelle membraneGO:00310905100%8.58%4.58E-6(7.4E-3)
membraneGO:00160205100%15.38%8.54E-5(0.14)
mitochondrionGO:00057395100%15.78%9.72E-5(0.16)
cytoplasmGO:00057375100%55.64%0.05(n.s)
intracellular membrane-bound organelleGO:00432315100%55.65%0.05(n.s)
membrane-bound organelleGO:00432275100%55.65%0.05(n.s)
organelleGO:00432265100%60.56%0.08(n.s)
intracellular organelleGO:00432295100%60.56%0.08(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
cellGO:00056235100%83.5%0.41(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_80 (n = 7)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
amino acid metabolismGO:0006520571.43%2.82%3.38E-7(5.47E-4)
amino acid and derivative metabolismGO:0006519571.43%3.05%5.03E-7(8.13E-4)
amine metabolismGO:0009308571.43%3.38%8.34E-7(1.35E-3)
phenylalanyl-tRNA aminoacylationGO:0006432228.57%0.03%1.01E-6(1.63E-3)
oxaloacetate metabolismGO:0006107228.57%0.03%1.01E-6(1.63E-3)
aspartate metabolismGO:0006531228.57%0.03%1.01E-6(1.63E-3)
asparagine biosynthesis from oxaloacetateGO:0019266228.57%0.03%1.01E-6(1.63E-3)
aspartate catabolismGO:0006533228.57%0.03%1.01E-6(1.63E-3)
aspartate biosynthesisGO:0006532228.57%0.03%1.01E-6(1.63E-3)
nitrogen compound metabolismGO:0006807571.43%3.66%1.24E-6(2E-3)
tRNA aminoacylationGO:0043039342.86%0.46%3.13E-6(5.06E-3)
amino acid activationGO:0043038342.86%0.46%3.13E-6(5.06E-3)
tRNA aminoacylation for protein translationGO:0006418342.86%0.46%3.13E-6(5.06E-3)
organic acid metabolismGO:0006082571.43%4.6%3.88E-6(6.27E-3)
carboxylic acid metabolismGO:0019752571.43%4.6%3.88E-6(6.27E-3)
cellular biosynthesisGO:00442497100%17.05%4.13E-6(6.67E-3)
asparagine biosynthesisGO:0006529228.57%0.06%6.04E-6(9.76E-3)
biosynthesisGO:00090587100%18.28%6.72E-6(0.01)
tRNA modificationGO:0006400342.86%1.02%3.47E-5(0.06)
asparagine metabolismGO:0006528228.57%0.14%3.62E-5(0.06)
aspartate family amino acid catabolismGO:0009068228.57%0.15%4.52E-5(0.07)
cellular macromolecule metabolismGO:00442607100%24.52%5.28E-5(0.09)
macromolecule metabolismGO:00431707100%26.04%8.04E-5(0.13)
tRNA metabolismGO:0006399342.86%1.6%1.32E-4(0.21)
aspartate family amino acid biosynthesisGO:0009067228.57%0.28%1.53E-4(0.25)
tricarboxylic acid cycle intermediate metabolismGO:0006100228.57%0.29%1.71E-4(0.28)
amino acid catabolismGO:0009063228.57%0.43%3.76E-4(0.61)
protein biosynthesisGO:0006412571.43%12.16%4.46E-4(0.72)
RNA modificationGO:0009451342.86%2.42%4.51E-4(0.73)
amine catabolismGO:0009310228.57%0.48%4.62E-4(0.75)
nitrogen compound catabolismGO:0044270228.57%0.48%4.62E-4(0.75)
macromolecule biosynthesisGO:0009059571.43%13.04%6.24E-4(n.s)
aspartate family amino acid metabolismGO:0009066228.57%0.7%9.76E-4(n.s)
tyrosyl-tRNA aminoacylationGO:0006437114.29%0.03%2.17E-3(n.s)
main pathways of carbohydrate metabolismGO:0006092228.57%1.08%2.35E-3(n.s)
amino acid biosynthesisGO:0008652228.57%1.53%4.65E-3(n.s)
amine biosynthesisGO:0009309228.57%1.67%5.51E-3(n.s)
nitrogen compound biosynthesisGO:0044271228.57%1.67%5.51E-3(n.s)
primary metabolismGO:00442387100%48.71%6.49E-3(n.s)
cellular protein metabolismGO:0044267571.43%21.7%6.76E-3(n.s)
protein metabolismGO:0019538571.43%22.06%7.28E-3(n.s)
translationGO:0043037342.86%6.47%7.75E-3(n.s)
cellular metabolismGO:00442377100%52.12%0.01(n.s)
metabolismGO:00081527100%52.93%0.01(n.s)
RNA metabolismGO:0016070342.86%8.32%0.02(n.s)
glutamate metabolismGO:0006536114.29%0.25%0.02(n.s)
energy derivation by oxidation of organic compoundsGO:0015980228.57%3.04%0.02(n.s)
cellular carbohydrate metabolismGO:0044262228.57%3.08%0.02(n.s)
biopolymer modificationGO:0043412342.86%9.25%0.02(n.s)
carbohydrate metabolismGO:0005975228.57%3.38%0.02(n.s)
generation of precursor metabolites and energyGO:0006091228.57%3.5%0.02(n.s)
glutamine family amino acid metabolismGO:0009064114.29%0.67%0.05(n.s)
cellular catabolismGO:0044248228.57%5.84%0.06(n.s)
catabolismGO:0009056228.57%6.16%0.06(n.s)
cellular physiological processGO:00508757100%71.65%0.1(n.s)
cellular processGO:00099877100%72.29%0.1(n.s)
physiological processGO:00075827100%73.68%0.12(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139342.86%23.17%0.21(n.s)
biopolymer metabolismGO:0043283342.86%25.06%0.24(n.s)
biological_processGO:00081507100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ligase activity, forming carbon-oxygen bondsGO:0016875571.43%0.56%8.42E-11(1.36E-7)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876571.43%0.56%8.42E-11(1.36E-7)
tRNA ligase activityGO:0004812571.43%0.56%8.42E-11(1.36E-7)
RNA ligase activityGO:0008452571.43%0.57%9.73E-11(1.57E-7)
ligase activity, forming phosphoric ester bondsGO:0016886571.43%0.62%1.47E-10(2.37E-7)
phenylalanine-tRNA ligase activityGO:0004826342.86%0.05%7.81E-10(1.26E-6)
ligase activityGO:0016874571.43%1.89%4.52E-8(7.31E-5)
aspartate transaminase activityGO:0004069228.57%0.03%1.01E-6(1.63E-3)
transferase activity, transferring nitrogenous groupsGO:0016769228.57%0.25%1.2E-4(0.19)
transaminase activityGO:0008483228.57%0.25%1.2E-4(0.19)
catalytic activityGO:00038247100%29.21%1.8E-4(0.29)
aspartate-tRNA ligase activityGO:0004815114.29%0.03%2.17E-3(n.s)
tyrosine-tRNA ligase activityGO:0004831114.29%0.03%2.17E-3(n.s)
transferase activityGO:0016740228.57%10.13%0.15(n.s)
molecular_functionGO:00036747100%99.44%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
phenylalanine-tRNA ligase complexGO:0009328228.57%0.03%1.01E-6(1.63E-3)
unlocalized protein complexGO:0005941228.57%0.57%6.59E-4(n.s)
mitochondrionGO:0005739457.14%15.78%0.01(n.s)
cytoplasmGO:00057377100%55.64%0.02(n.s)
peroxisomeGO:0005777114.29%0.87%0.06(n.s)
microbodyGO:0042579114.29%0.87%0.06(n.s)
intracellularGO:00056227100%77.03%0.16(n.s)
cellGO:00056237100%83.5%0.28(n.s)
intracellular membrane-bound organelleGO:0043231571.43%55.65%0.33(n.s)
membrane-bound organelleGO:0043227571.43%55.65%0.33(n.s)
organelleGO:0043226571.43%60.56%0.43(n.s)
intracellular organelleGO:0043229571.43%60.56%0.43(n.s)
protein complexGO:0043234228.57%21.07%0.45(n.s)
cellular_componentGO:00055757100%99.61%0.97(n.s)

 

 

cluster_7 (n = 11)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ubiquinone metabolismGO:0006743872.73%0.12%2.21E-24(3.58E-21)
oxidoreduction coenzyme metabolismGO:0006733872.73%0.67%3.16E-16(5.11E-13)
coenzyme metabolismGO:0006732872.73%1.81%1.44E-12(2.33E-9)
cofactor metabolismGO:0051186872.73%2.26%8.8E-12(1.42E-8)
quinone cofactor biosynthesisGO:0045426218.18%0.03%2.64E-6(4.27E-3)
ubiquinone biosynthesisGO:0006744218.18%0.03%2.64E-6(4.27E-3)
quinone cofactor metabolismGO:0042375218.18%0.03%2.64E-6(4.27E-3)
coenzyme biosynthesisGO:0009108218.18%0.87%3.87E-3(n.s)
aromatic compound catabolismGO:001943919.09%0.05%5.1E-3(n.s)
cofactor biosynthesisGO:0051188218.18%1.08%5.98E-3(n.s)
cellular metabolismGO:00442371090.91%52.12%8.52E-3(n.s)
metabolismGO:00081521090.91%52.93%9.8E-3(n.s)
ergosterol metabolismGO:000820419.09%0.39%0.04(n.s)
ergosterol biosynthesisGO:000669619.09%0.39%0.04(n.s)
sterol biosynthesisGO:001612619.09%0.45%0.05(n.s)
steroid biosynthesisGO:000669419.09%0.56%0.06(n.s)
sterol metabolismGO:001612519.09%0.57%0.06(n.s)
steroid metabolismGO:000820219.09%0.7%0.07(n.s)
aromatic compound metabolismGO:000672519.09%0.88%0.09(n.s)
aerobic respirationGO:000906019.09%1.27%0.13(n.s)
cellular physiological processGO:00508751090.91%71.65%0.14(n.s)
cellular respirationGO:004533319.09%1.35%0.14(n.s)
cellular processGO:00099871090.91%72.29%0.15(n.s)
physiological processGO:00075821090.91%73.68%0.17(n.s)
lipid biosynthesisGO:000861019.09%1.92%0.19(n.s)
alcohol metabolismGO:000606619.09%2.43%0.24(n.s)
energy derivation by oxidation of organic compoundsGO:001598019.09%3.04%0.29(n.s)
cellular lipid metabolismGO:004425519.09%3.16%0.3(n.s)
lipid metabolismGO:000662919.09%3.38%0.31(n.s)
generation of precursor metabolites and energyGO:000609119.09%3.5%0.32(n.s)
biosynthesisGO:0009058327.27%18.28%0.33(n.s)
cellular catabolismGO:004424819.09%5.84%0.48(n.s)
catabolismGO:000905619.09%6.16%0.5(n.s)
cellular biosynthesisGO:0044249218.18%17.05%0.58(n.s)
biological process unknownGO:000000419.09%25.64%0.96(n.s)
biological_processGO:000815011100%99.98%1(n.s)
primary metabolismGO:004423819.09%48.71%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transferase activity, transferring alkyl or aryl (other than methyl) groupsGO:0016765218.18%0.53%1.44E-3(n.s)
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activityGO:004333419.09%0.02%**
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activityGO:000842519.09%0.02%**
C-5 sterol desaturase activityGO:000024819.09%0.02%**
hexaprenyldihydroxybenzoate methyltransferase activityGO:000439519.09%0.02%**
trans-hexaprenyltranstransferase activityGO:000001019.09%0.02%**
quinone cofactor methyltransferase activityGO:003058019.09%0.02%**
ubiquinone biosynthesis monooxygenase activityGO:001599719.09%0.02%**
isoprenoid bindingGO:001984019.09%0.02%**
C-methyltransferase activityGO:000816919.09%0.05%5.1E-3(n.s)
methyltransferase activityGO:0008168218.18%1.1%6.15E-3(n.s)
transferase activity, transferring one-carbon groupsGO:0016741218.18%1.13%6.49E-3(n.s)
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygenGO:001670919.09%0.06%6.8E-3(n.s)
monooxygenase activityGO:000449719.09%0.09%0.01(n.s)
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenGO:001670519.09%0.12%0.01(n.s)
catalytic activityGO:0003824763.64%29.21%0.02(n.s)
transferase activityGO:0016740436.36%10.13%0.02(n.s)
prenyltransferase activityGO:000465919.09%0.2%0.02(n.s)
oxidoreductase activity, acting on the CH-CH group of donorsGO:001662719.09%0.29%0.03(n.s)
carboxy-lyase activityGO:001683119.09%0.31%0.03(n.s)
carbon-carbon lyase activityGO:001683019.09%0.43%0.05(n.s)
oxidoreductase activityGO:0016491218.18%3.73%0.06(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:000875719.09%0.77%0.08(n.s)
lyase activityGO:001682919.09%1.27%0.13(n.s)
carrier activityGO:000538619.09%1.64%0.17(n.s)
transporter activityGO:000521519.09%6.64%0.53(n.s)
molecular function unknownGO:0005554436.36%35.75%0.6(n.s)
bindingGO:000548819.09%17.35%0.88(n.s)
molecular_functionGO:000367411100%99.44%0.94(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057391090.91%15.78%8.72E-8(1.41E-4)
mitochondrial inner membraneGO:0005743545.45%2.43%3.28E-6(5.3E-3)
inner membraneGO:0019866545.45%2.43%3.28E-6(5.3E-3)
mitochondrial membraneGO:0005740545.45%3.16%1.19E-5(0.02)
organelle membraneGO:0031090545.45%8.58%1.36E-3(n.s)
cytoplasmGO:000573711100%55.64%1.57E-3(n.s)
intracellular membrane-bound organelleGO:004323111100%55.65%1.58E-3(n.s)
membrane-bound organelleGO:004322711100%55.65%1.58E-3(n.s)
organelleGO:004322611100%60.56%4E-3(n.s)
intracellular organelleGO:004322911100%60.56%4E-3(n.s)
membraneGO:0016020545.45%15.38%0.02(n.s)
extrinsic to membraneGO:001989819.09%0.48%0.05(n.s)
intracellularGO:000562211100%77.03%0.06(n.s)
cellGO:000562311100%83.5%0.14(n.s)
endoplasmic reticulumGO:000578319.09%5.84%0.48(n.s)
cellular_componentGO:000557511100%99.61%0.96(n.s)

 

 

cluster_103 (n = 10)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
acetate metabolismGO:0006083440%0.11%1.01E-10(1.64E-7)
fermentationGO:0006113440%0.25%5.24E-9(8.46E-6)
acetyl-CoA metabolismGO:0006084330%0.31%3.01E-6(4.86E-3)
generation of precursor metabolites and energyGO:0006091550%3.5%1.1E-5(0.02)
acetyl-CoA biosynthesisGO:0006085220%0.06%1.29E-5(0.02)
acetate biosynthesisGO:0019413220%0.06%1.29E-5(0.02)
energy derivation by oxidation of organic compoundsGO:0015980440%3.04%1.5E-4(0.24)
carboxylic acid biosynthesisGO:0046394220%0.26%2.9E-4(0.47)
organic acid biosynthesisGO:0016053220%0.26%2.9E-4(0.47)
coenzyme metabolismGO:0006732330%1.81%6.34E-4(n.s)
organic acid metabolismGO:0006082440%4.6%7.39E-4(n.s)
carboxylic acid metabolismGO:0019752440%4.6%7.39E-4(n.s)
cofactor metabolismGO:0051186330%2.26%1.21E-3(n.s)
cellular metabolismGO:004423710100%52.12%1.47E-3(n.s)
acetate fermentationGO:0019654110%0.02%**
metabolismGO:000815210100%52.93%1.71E-3(n.s)
formaldehyde metabolismGO:0046292110%0.03%3.1E-3(n.s)
formaldehyde catabolismGO:0046294110%0.03%3.1E-3(n.s)
aldehyde catabolismGO:0046185110%0.08%7.72E-3(n.s)
ethanol metabolismGO:0006067110%0.15%0.02(n.s)
one-carbon compound metabolismGO:0006730110%0.19%0.02(n.s)
aldehyde metabolismGO:0006081110%0.29%0.03(n.s)
cellular physiological processGO:005087510100%71.65%0.04(n.s)
cellular processGO:000998710100%72.29%0.04(n.s)
electron transportGO:0006118110%0.48%0.05(n.s)
physiological processGO:000758210100%73.68%0.05(n.s)
alcohol metabolismGO:0006066110%2.43%0.22(n.s)
cellular catabolismGO:0044248110%5.84%0.45(n.s)
catabolismGO:0009056110%6.16%0.47(n.s)
cellular biosynthesisGO:0044249220%17.05%0.53(n.s)
biosynthesisGO:0009058220%18.28%0.57(n.s)
transportGO:0006810110%14.27%0.79(n.s)
establishment of localizationGO:0051234110%14.39%0.79(n.s)
localizationGO:0051179110%14.82%0.8(n.s)
biological_processGO:000815010100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
alcohol dehydrogenase activityGO:0004022440%0.09%4.35E-11(7.03E-8)
oxidoreductase activityGO:0016491770%3.73%1.01E-8(1.63E-5)
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorGO:0016620440%0.29%1.11E-8(1.8E-5)
oxidoreductase activity, acting on the aldehyde or oxo group of donorsGO:0016903440%0.36%2.54E-8(4.1E-5)
aldehyde dehydrogenase activityGO:0004028330%0.09%5.34E-8(8.63E-5)
acetate-CoA ligase activityGO:0003987220%0.03%2.16E-6(3.49E-3)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616440%1.07%2.39E-6(3.86E-3)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614440%1.18%3.53E-6(5.71E-3)
catalytic activityGO:000382410100%29.21%4.45E-6(7.19E-3)
acid-thiol ligase activityGO:0016878220%0.06%1.29E-5(0.02)
CoA-ligase activityGO:0016405220%0.06%1.29E-5(0.02)
ligase activity, forming carbon-sulfur bondsGO:0016877220%0.14%7.73E-5(0.12)
acetyl-CoA hydrolase activityGO:0003986110%0.02%**
alcohol dehydrogenase activity, zinc-dependentGO:0004024110%0.02%**
formaldehyde dehydrogenase (glutathione) activityGO:0004327110%0.02%**
aldehyde dehydrogenase (NAD) activityGO:0004029110%0.03%3.1E-3(n.s)
CoA hydrolase activityGO:0016289110%0.05%4.64E-3(n.s)
thiolester hydrolase activityGO:0016790110%0.08%7.72E-3(n.s)
ligase activityGO:0016874220%1.89%0.01(n.s)
hydrolase activity, acting on ester bondsGO:0016788110%4.12%0.34(n.s)
hydrolase activityGO:0016787110%11.45%0.7(n.s)
molecular_functionGO:000367410100%99.44%0.95(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739880%15.78%1.25E-5(0.02)
cytoplasmGO:000573710100%55.64%2.83E-3(n.s)
cytosolGO:0005829440%10.08%0.01(n.s)
mitochondrial matrixGO:0005759220%2.52%0.02(n.s)
nucleoidGO:0009295110%0.36%0.04(n.s)
mitochondrial nucleoidGO:0042645110%0.36%0.04(n.s)
soluble fractionGO:0005625110%0.56%0.05(n.s)
intracellularGO:000562210100%77.03%0.07(n.s)
intracellular membrane-bound organelleGO:0043231880%55.65%0.11(n.s)
membrane-bound organelleGO:0043227880%55.65%0.11(n.s)
cell fractionGO:0000267110%1.72%0.16(n.s)
cellGO:000562310100%83.5%0.16(n.s)
organelleGO:0043226880%60.56%0.18(n.s)
intracellular organelleGO:0043229880%60.56%0.18(n.s)
cellular_componentGO:000557510100%99.61%0.96(n.s)

 

 

cluster_105 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA repairGO:0006281480%2.32%1.38E-6(2.22E-3)
response to DNA damage stimulusGO:0006974480%2.73%2.61E-6(4.22E-3)
response to endogenous stimulusGO:0009719480%2.82%2.99E-6(4.83E-3)
DNA metabolismGO:00062595100%8.58%4.58E-6(7.4E-3)
response to stressGO:0006950480%6.09%6.44E-5(0.1)
M phase of meiotic cell cycleGO:0051327360%2%7.57E-5(0.12)
meiotic cell cycleGO:0051321360%2%7.57E-5(0.12)
meiosisGO:0007126360%2%7.57E-5(0.12)
maintenance of fidelity during DNA-dependent DNA replicationGO:0045005240%0.31%9.07E-5(0.15)
mismatch repairGO:0006298240%0.31%9.07E-5(0.15)
response to stimulusGO:0050896480%8.41%2.31E-4(0.37)
meiotic recombinationGO:0007131240%0.6%3.52E-4(0.57)
M phaseGO:0000279360%3.98%5.88E-4(0.95)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061395100%23.17%6.65E-4(n.s)
meiosis IGO:0007127240%0.85%7.01E-4(n.s)
biopolymer metabolismGO:00432835100%25.06%9.84E-4(n.s)
DNA-dependent DNA replicationGO:0006261240%1.24%1.48E-3(n.s)
cell cycleGO:0007049360%6.12%2.07E-3(n.s)
DNA replicationGO:0006260240%1.6%2.44E-3(n.s)
DNA recombinationGO:0006310240%2.91%7.96E-3(n.s)
primary metabolismGO:00442385100%48.71%0.03(n.s)
cellular metabolismGO:00442375100%52.12%0.04(n.s)
metabolismGO:00081525100%52.93%0.04(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ATP bindingGO:0005524360%0.22%8.1E-8(1.31E-4)
adenyl nucleotide bindingGO:0030554360%0.26%1.51E-7(2.44E-4)
purine nucleotide bindingGO:0017076360%0.5%1.1E-6(1.78E-3)
nucleotide bindingGO:0000166360%0.51%1.21E-6(1.95E-3)
ATPase activityGO:0016887240%2.52%6.03E-3(n.s)
DNA bindingGO:0003677240%3.18%9.42E-3(n.s)
nucleoside-triphosphatase activityGO:0017111240%3.42%0.01(n.s)
pyrophosphatase activityGO:0016462240%3.67%0.01(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817240%3.69%0.01(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818240%3.69%0.01(n.s)
bindingGO:0005488360%17.35%0.04(n.s)
nucleic acid bindingGO:0003676240%9.87%0.08(n.s)
hydrolase activityGO:0016787240%11.45%0.1(n.s)
catalytic activityGO:0003824240%29.21%0.46(n.s)
molecular function unknownGO:0005554240%35.75%0.59(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nucleusGO:0005634480%31.01%0.03(n.s)
intracellular membrane-bound organelleGO:00432315100%55.65%0.05(n.s)
membrane-bound organelleGO:00432275100%55.65%0.05(n.s)
organelleGO:00432265100%60.56%0.08(n.s)
intracellular organelleGO:00432295100%60.56%0.08(n.s)
nuclear chromosomeGO:0000228120%2.31%0.11(n.s)
chromosomeGO:0005694120%3.16%0.15(n.s)
mitochondrionGO:0005739240%15.78%0.18(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
cellGO:00056235100%83.5%0.41(n.s)
intracellular non-membrane-bound organelleGO:0043232120%14.3%0.54(n.s)
non-membrane-bound organelleGO:0043228120%14.3%0.54(n.s)
cytoplasmGO:0005737240%55.64%0.88(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_31 (n = 6)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
amino acid metabolismGO:0006520583.33%2.82%9.89E-8(1.6E-4)
glutamate biosynthesisGO:0006537350%0.2%1.27E-7(2.05E-4)
amino acid and derivative metabolismGO:0006519583.33%3.05%1.47E-7(2.38E-4)
amine metabolismGO:0009308583.33%3.38%2.45E-7(3.96E-4)
glutamate metabolismGO:0006536350%0.25%2.49E-7(4.02E-4)
nitrogen compound metabolismGO:0006807583.33%3.66%3.65E-7(5.89E-4)
glutamine family amino acid biosynthesisGO:0009084350%0.37%8.96E-7(1.45E-3)
organic acid metabolismGO:0006082583.33%4.6%1.15E-6(1.86E-3)
carboxylic acid metabolismGO:0019752583.33%4.6%1.15E-6(1.86E-3)
glutamine family amino acid metabolismGO:0009064350%0.67%5.43E-6(8.77E-3)
amino acid biosynthesisGO:0008652350%1.53%6.77E-5(0.11)
amine biosynthesisGO:0009309350%1.67%8.78E-5(0.14)
nitrogen compound biosynthesisGO:0044271350%1.67%8.78E-5(0.14)
tRNA aminoacylationGO:0043039233.33%0.46%3.1E-4(0.5)
amino acid activationGO:0043038233.33%0.46%3.1E-4(0.5)
tRNA aminoacylation for protein translationGO:0006418233.33%0.46%3.1E-4(0.5)
cellular biosynthesisGO:0044249583.33%17.05%7.37E-4(n.s)
alanyl-tRNA aminoacylationGO:0006419116.67%0.02%**
biosynthesisGO:0009058583.33%18.28%1.03E-3(n.s)
tRNA modificationGO:0006400233.33%1.02%1.5E-3(n.s)
glutamyl-tRNA aminoacylationGO:0006424116.67%0.03%1.86E-3(n.s)
tRNA metabolismGO:0006399233.33%1.6%3.63E-3(n.s)
proline catabolismGO:0006562116.67%0.06%3.71E-3(n.s)
proline metabolismGO:0006560116.67%0.11%6.49E-3(n.s)
RNA modificationGO:0009451233.33%2.42%8.16E-3(n.s)
glutamine family amino acid catabolismGO:0009065116.67%0.2%0.01(n.s)
amino acid catabolismGO:0009063116.67%0.43%0.03(n.s)
amine catabolismGO:0009310116.67%0.48%0.03(n.s)
nitrogen compound catabolismGO:0044270116.67%0.48%0.03(n.s)
translationGO:0043037233.33%6.47%0.05(n.s)
RNA metabolismGO:0016070233.33%8.32%0.08(n.s)
primary metabolismGO:0044238583.33%48.71%0.1(n.s)
biopolymer modificationGO:0043412233.33%9.25%0.1(n.s)
cellular metabolismGO:0044237583.33%52.12%0.13(n.s)
metabolismGO:0008152583.33%52.93%0.14(n.s)
protein biosynthesisGO:0006412233.33%12.16%0.16(n.s)
macromolecule biosynthesisGO:0009059233.33%13.04%0.18(n.s)
cellular catabolismGO:0044248116.67%5.84%0.3(n.s)
catabolismGO:0009056116.67%6.16%0.32(n.s)
cellular protein metabolismGO:0044267233.33%21.7%0.39(n.s)
protein metabolismGO:0019538233.33%22.06%0.4(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139233.33%23.17%0.42(n.s)
cellular macromolecule metabolismGO:0044260233.33%24.52%0.45(n.s)
cellular physiological processGO:0050875583.33%71.65%0.46(n.s)
biopolymer metabolismGO:0043283233.33%25.06%0.47(n.s)
cellular processGO:0009987583.33%72.29%0.47(n.s)
macromolecule metabolismGO:0043170233.33%26.04%0.49(n.s)
physiological processGO:0007582583.33%73.68%0.5(n.s)
biological process unknownGO:0000004116.67%25.64%0.83(n.s)
biological_processGO:00081506100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptorGO:0016639233.33%0.06%4.32E-6(6.97E-3)
oxidoreductase activity, acting on the CH-NH2 group of donorsGO:0016638233.33%0.09%1.08E-5(0.02)
ligase activity, forming carbon-oxygen bondsGO:0016875233.33%0.56%4.47E-4(0.72)
tRNA ligase activityGO:0004812233.33%0.56%4.47E-4(0.72)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876233.33%0.56%4.47E-4(0.72)
RNA ligase activityGO:0008452233.33%0.57%4.73E-4(0.76)
ligase activity, forming phosphoric ester bondsGO:0016886233.33%0.62%5.53E-4(0.89)
catalytic activityGO:00038246100%29.21%6.18E-4(1)
glutamate synthase activityGO:0015930116.67%0.02%**
glutamate synthase activity, NADH or NADPH as acceptorGO:0045181116.67%0.02%**
glutamate synthase (NADH) activityGO:0016040116.67%0.02%**
alanine-tRNA ligase activityGO:0004813116.67%0.02%**
1-pyrroline-5-carboxylate dehydrogenase activityGO:0003842116.67%0.02%**
oxidoreductase activityGO:0016491350%3.73%9.45E-4(n.s)
glutamate-tRNA ligase activityGO:0004818116.67%0.03%1.86E-3(n.s)
glutamate dehydrogenase activityGO:0004352116.67%0.03%1.86E-3(n.s)
ligase activityGO:0016874233.33%1.89%5.06E-3(n.s)
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptorGO:0016646116.67%0.19%0.01(n.s)
oxidoreductase activity, acting on the CH-NH group of donorsGO:0016645116.67%0.22%0.01(n.s)
transferase activity, transferring nitrogenous groupsGO:0016769116.67%0.25%0.01(n.s)
transaminase activityGO:0008483116.67%0.25%0.01(n.s)
transferase activityGO:0016740116.67%10.13%0.47(n.s)
molecular_functionGO:00036746100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057396100%15.78%1.53E-5(0.02)
glutamate synthase complexGO:0031026116.67%0.02%**
cytoplasmGO:00057376100%55.64%0.03(n.s)
intracellular membrane-bound organelleGO:00432316100%55.65%0.03(n.s)
membrane-bound organelleGO:00432276100%55.65%0.03(n.s)
soluble fractionGO:0005625116.67%0.56%0.03(n.s)
organelleGO:00432266100%60.56%0.05(n.s)
intracellular organelleGO:00432296100%60.56%0.05(n.s)
cell fractionGO:0000267116.67%1.72%0.1(n.s)
intracellularGO:00056226100%77.03%0.21(n.s)
cellGO:00056236100%83.5%0.34(n.s)
protein complexGO:0043234116.67%21.07%0.76(n.s)
nucleusGO:0005634116.67%31.01%0.89(n.s)
cellular_componentGO:00055756100%99.61%0.98(n.s)

 

 

cluster_30 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glycerophospholipid biosynthesisGO:0046474240%0.53%2.67E-4(0.43)
cellular lipid metabolismGO:0044255360%3.16%2.97E-4(0.48)
lipid metabolismGO:0006629360%3.38%3.61E-4(0.58)
glycerophospholipid metabolismGO:0006650240%0.68%4.48E-4(0.72)
carboxylic acid transportGO:0046942240%0.77%5.79E-4(0.94)
organic acid transportGO:0015849240%0.79%6.03E-4(0.97)
phospholipid biosynthesisGO:0008654240%0.81%6.27E-4(n.s)
oxaloacetate transportGO:0015729120%0.02%**
phosphatidic acid metabolismGO:0046473120%0.02%**
phosphatidic acid biosynthesisGO:0006654120%0.02%**
membrane lipid biosynthesisGO:0046467240%1.1%1.17E-3(n.s)
phospholipid metabolismGO:0006644240%1.19%1.37E-3(n.s)
tricarboxylic acid transportGO:0006842120%0.03%1.55E-3(n.s)
very-long-chain fatty acid metabolismGO:0000038120%0.03%1.55E-3(n.s)
dicarboxylic acid transportGO:0006835120%0.05%2.32E-3(n.s)
sulfate transportGO:0008272120%0.05%2.32E-3(n.s)
membrane lipid metabolismGO:0006643240%1.61%2.49E-3(n.s)
lipid biosynthesisGO:0008610240%1.92%3.52E-3(n.s)
phosphatidylcholine biosynthesisGO:0006656120%0.11%5.41E-3(n.s)
phosphatidylcholine metabolismGO:0046470120%0.14%6.95E-3(n.s)
inorganic anion transportGO:0015698120%0.25%0.01(n.s)
carboxylic acid biosynthesisGO:0046394120%0.26%0.01(n.s)
anion transportGO:0006820120%0.26%0.01(n.s)
organic acid biosynthesisGO:0016053120%0.26%0.01(n.s)
organic acid metabolismGO:0006082240%4.6%0.02(n.s)
carboxylic acid metabolismGO:0019752240%4.6%0.02(n.s)
mitochondrial genome maintenanceGO:0000002120%0.42%0.02(n.s)
fatty acid metabolismGO:0006631120%0.67%0.03(n.s)
mitochondrion organization and biogenesisGO:0007005120%1.47%0.07(n.s)
ion transportGO:0006811120%1.64%0.08(n.s)
transportGO:0006810240%14.27%0.15(n.s)
establishment of localizationGO:0051234240%14.39%0.15(n.s)
localizationGO:0051179240%14.82%0.16(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
biosynthesisGO:0009058240%18.28%0.23(n.s)
primary metabolismGO:0044238360%48.71%0.48(n.s)
cellular metabolismGO:0044237360%52.12%0.54(n.s)
metabolismGO:0008152360%52.93%0.55(n.s)
organelle organization and biogenesisGO:0006996120%15.69%0.57(n.s)
cellular biosynthesisGO:0044249120%17.05%0.61(n.s)
cell organization and biogenesisGO:0016043120%17.98%0.63(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
porter activityGO:0015291240%0.59%3.34E-4(0.54)
electrochemical potential-driven transporter activityGO:0015290240%0.59%3.34E-4(0.54)
oxaloacetate transporter activityGO:0015131120%0.02%**
sulfate porter activityGO:0008271120%0.02%**
acylglycerone-phosphate reductase activityGO:0000140120%0.02%**
oxaloacetate carrier activityGO:0000227120%0.02%**
phosphatidylserine decarboxylase activityGO:0004609120%0.03%1.55E-3(n.s)
tricarboxylate carrier activityGO:0005371120%0.03%1.55E-3(n.s)
sulfate transporter activityGO:0015116120%0.05%2.32E-3(n.s)
dicarboxylic acid transporter activityGO:0005310120%0.05%2.32E-3(n.s)
carrier activityGO:0005386240%1.64%2.59E-3(n.s)
inorganic anion transporter activityGO:0015103120%0.2%0.01(n.s)
oxidoreductase activityGO:0016491240%3.73%0.01(n.s)
anion transporter activityGO:0008509120%0.28%0.01(n.s)
carboxy-lyase activityGO:0016831120%0.31%0.02(n.s)
carbon-carbon lyase activityGO:0016830120%0.43%0.02(n.s)
carboxylic acid transporter activityGO:0046943120%0.74%0.04(n.s)
transporter activityGO:0005215240%6.64%0.04(n.s)
organic acid transporter activityGO:0005342120%0.79%0.04(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616120%1.07%0.05(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614120%1.18%0.06(n.s)
lyase activityGO:0016829120%1.27%0.06(n.s)
ion transporter activityGO:0015075120%2.21%0.11(n.s)
DNA bindingGO:0003677120%3.18%0.15(n.s)
catalytic activityGO:0003824360%29.21%0.15(n.s)
nucleic acid bindingGO:0003676120%9.87%0.41(n.s)
bindingGO:0005488120%17.35%0.61(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057395100%15.78%9.72E-5(0.16)
mitochondrial inner membraneGO:0005743360%2.43%1.36E-4(0.22)
inner membraneGO:0019866360%2.43%1.36E-4(0.22)
organelle membraneGO:0031090480%8.58%2.5E-4(0.4)
mitochondrial membraneGO:0005740360%3.16%2.97E-4(0.48)
membraneGO:0016020480%15.38%2.44E-3(n.s)
nucleoidGO:0009295120%0.36%0.02(n.s)
mitochondrial nucleoidGO:0042645120%0.36%0.02(n.s)
lipid particleGO:0005811120%0.51%0.03(n.s)
endoplasmic reticulumGO:0005783240%5.84%0.03(n.s)
cytoplasmGO:00057375100%55.64%0.05(n.s)
intracellular membrane-bound organelleGO:00432315100%55.65%0.05(n.s)
membrane-bound organelleGO:00432275100%55.65%0.05(n.s)
organelleGO:00432265100%60.56%0.08(n.s)
intracellular organelleGO:00432295100%60.56%0.08(n.s)
endoplasmic reticulum membraneGO:0005789120%1.78%0.09(n.s)
nuclear envelope-endoplasmic reticulum networkGO:0042175120%1.95%0.09(n.s)
mitochondrial matrixGO:0005759120%2.52%0.12(n.s)
endomembrane systemGO:0012505120%3.7%0.17(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
cellGO:00056235100%83.5%0.41(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_37 (n = 13)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
pyruvate metabolismGO:0006090753.85%0.57%1.86E-13(3.01E-10)
organic acid metabolismGO:0006082969.23%4.6%4.98E-10(8.05E-7)
carboxylic acid metabolismGO:0019752969.23%4.6%4.98E-10(8.05E-7)
acetyl-CoA metabolismGO:0006084430.77%0.31%4.71E-8(7.6E-5)
acetyl-CoA biosynthesis from pyruvateGO:0006086215.38%0.03%3.74E-6(6.05E-3)
2-oxoglutarate metabolismGO:0006103215.38%0.03%3.74E-6(6.05E-3)
ketone metabolismGO:0042180215.38%0.06%2.24E-5(0.04)
acetyl-CoA biosynthesisGO:0006085215.38%0.06%2.24E-5(0.04)
coenzyme metabolismGO:0006732430.77%1.81%6.46E-5(0.1)
cofactor metabolismGO:0051186430.77%2.26%1.53E-4(0.25)
tricarboxylic acid cycleGO:0006099215.38%0.23%3.87E-4(0.63)
acetyl-CoA catabolismGO:0046356215.38%0.23%3.87E-4(0.63)
coenzyme catabolismGO:0009109215.38%0.26%5E-4(0.81)
cofactor catabolismGO:0051187215.38%0.28%5.62E-4(0.91)
tricarboxylic acid cycle intermediate metabolismGO:0006100215.38%0.29%6.28E-4(n.s)
isoleucine catabolismGO:000655017.69%0.02%**
valine metabolismGO:000657317.69%0.02%**
valine catabolismGO:000657417.69%0.02%**
leucine catabolismGO:000655217.69%0.03%4.02E-3(n.s)
L-serine biosynthesisGO:000656417.69%0.03%4.02E-3(n.s)
branched chain family amino acid catabolismGO:000908317.69%0.03%4.02E-3(n.s)
L-serine metabolismGO:000656317.69%0.03%4.02E-3(n.s)
cellular catabolismGO:0044248430.77%5.84%5.37E-3(n.s)
isoleucine metabolismGO:000654917.69%0.05%6.03E-3(n.s)
catabolismGO:0009056430.77%6.16%6.51E-3(n.s)
glycine catabolismGO:000654617.69%0.06%8.03E-3(n.s)
main pathways of carbohydrate metabolismGO:0006092215.38%1.08%8.37E-3(n.s)
serine family amino acid catabolismGO:000907117.69%0.08%0.01(n.s)
aerobic respirationGO:0009060215.38%1.27%0.01(n.s)
glycine metabolismGO:000654417.69%0.09%0.01(n.s)
cellular respirationGO:0045333215.38%1.35%0.01(n.s)
leucine metabolismGO:000655117.69%0.11%0.01(n.s)
regulation of DNA replicationGO:000627517.69%0.12%0.02(n.s)
cellular metabolismGO:00442371184.62%52.12%0.02(n.s)
metabolismGO:00081521184.62%52.93%0.02(n.s)
regulation of cell redox homeostasisGO:003050317.69%0.15%0.02(n.s)
cell redox homeostasisGO:004545417.69%0.15%0.02(n.s)
serine family amino acid biosynthesisGO:000907017.69%0.19%0.02(n.s)
branched chain family amino acid metabolismGO:000908117.69%0.25%0.03(n.s)
protein deubiquitinationGO:001657917.69%0.28%0.04(n.s)
regulation of DNA metabolismGO:005105217.69%0.31%0.04(n.s)
serine family amino acid metabolismGO:000906917.69%0.34%0.04(n.s)
amino acid metabolismGO:0006520215.38%2.82%0.05(n.s)
amino acid catabolismGO:000906317.69%0.43%0.05(n.s)
energy derivation by oxidation of organic compoundsGO:0015980215.38%3.04%0.06(n.s)
amino acid and derivative metabolismGO:0006519215.38%3.05%0.06(n.s)
cellular carbohydrate metabolismGO:0044262215.38%3.08%0.06(n.s)
amine catabolismGO:000931017.69%0.48%0.06(n.s)
nitrogen compound catabolismGO:004427017.69%0.48%0.06(n.s)
amine metabolismGO:0009308215.38%3.38%0.07(n.s)
carbohydrate metabolismGO:0005975215.38%3.38%0.07(n.s)
generation of precursor metabolites and energyGO:0006091215.38%3.5%0.07(n.s)
nitrogen compound metabolismGO:0006807215.38%3.66%0.08(n.s)
cellular physiological processGO:00508751292.31%71.65%0.08(n.s)
cellular processGO:00099871292.31%72.29%0.09(n.s)
physiological processGO:00075821292.31%73.68%0.11(n.s)
endocytosisGO:000689717.69%1.07%0.13(n.s)
ubiquitin cycleGO:000651217.69%1.07%0.13(n.s)
DNA-dependent DNA replicationGO:000626117.69%1.24%0.15(n.s)
amino acid biosynthesisGO:000865217.69%1.53%0.18(n.s)
DNA replicationGO:000626017.69%1.6%0.19(n.s)
cell homeostasisGO:001972517.69%1.64%0.19(n.s)
cellular macromolecule metabolismGO:0044260538.46%24.52%0.19(n.s)
amine biosynthesisGO:000930917.69%1.67%0.2(n.s)
nitrogen compound biosynthesisGO:004427117.69%1.67%0.2(n.s)
homeostasisGO:004259217.69%1.73%0.2(n.s)
macromolecule metabolismGO:0043170538.46%26.04%0.23(n.s)
protein complex assemblyGO:000646117.69%2.26%0.26(n.s)
cellular protein catabolismGO:004425717.69%2.42%0.27(n.s)
proteolysis and peptidolysisGO:000650817.69%2.42%0.27(n.s)
protein catabolismGO:003016317.69%2.74%0.3(n.s)
regulation of cellular physiological processGO:0051244215.38%8.49%0.3(n.s)
regulation of cellular processGO:0050794215.38%8.52%0.31(n.s)
regulation of physiological processGO:0050791215.38%8.77%0.32(n.s)
biopolymer catabolismGO:004328517.69%2.93%0.32(n.s)
regulation of biological processGO:0050789215.38%8.97%0.33(n.s)
vesicle-mediated transportGO:001619217.69%4.34%0.44(n.s)
cellular macromolecule catabolismGO:004426517.69%4.51%0.45(n.s)
primary metabolismGO:0044238753.85%48.71%0.46(n.s)
macromolecule catabolismGO:000905717.69%4.83%0.48(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:001921917.69%5.24%0.5(n.s)
regulation of cellular metabolismGO:003132317.69%5.98%0.55(n.s)
cellular protein metabolismGO:0044267323.08%21.7%0.56(n.s)
protein metabolismGO:0019538323.08%22.06%0.57(n.s)
regulation of metabolismGO:001922217.69%6.37%0.58(n.s)
protein modificationGO:000646417.69%6.68%0.59(n.s)
DNA metabolismGO:000625917.69%8.58%0.69(n.s)
biopolymer modificationGO:004341217.69%9.25%0.72(n.s)
transportGO:000681017.69%14.27%0.87(n.s)
establishment of localizationGO:005123417.69%14.39%0.87(n.s)
biopolymer metabolismGO:0043283215.38%25.06%0.87(n.s)
localizationGO:005117917.69%14.82%0.88(n.s)
cellular biosynthesisGO:004424917.69%17.05%0.91(n.s)
biosynthesisGO:000905817.69%18.28%0.93(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613917.69%23.17%0.97(n.s)
biological_processGO:00081501292.31%99.98%1.0

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptorGO:0016624323.08%0.05%6.38E-9(1.03E-5)
oxidoreductase activityGO:0016491646.15%3.73%3.5E-6(5.66E-3)
pyruvate dehydrogenase (acetyl-transferring) activityGO:0004739215.38%0.03%3.74E-6(6.05E-3)
pyruvate dehydrogenase activityGO:0004738215.38%0.03%3.74E-6(6.05E-3)
oxidoreductase activity, acting on the aldehyde or oxo group of donorsGO:0016903323.08%0.36%1.1E-5(0.02)
S-acyltransferase activityGO:0016417215.38%0.11%7.82E-5(0.13)
catalytic activityGO:00038241076.92%29.21%5.08E-4(0.82)
dihydrolipoyllysine-residue acetyltransferase activityGO:000474217.69%0.02%**
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activityGO:000447317.69%0.02%**
dihydrolipoyllysine-residue succinyltransferase activityGO:000414917.69%0.02%**
S-succinyltransferase activityGO:001675117.69%0.02%**
oxoglutarate dehydrogenase (succinyl-transferring) activityGO:000459117.69%0.02%**
dihydrolipoamide S-acyltransferase activityGO:003052317.69%0.02%**
dihydrolipoyl dehydrogenase activityGO:000414817.69%0.02%**
malic enzyme activityGO:000447017.69%0.02%**
S-acetyltransferase activityGO:001641817.69%0.03%4.02E-3(n.s)
succinyltransferase activityGO:001674817.69%0.03%4.02E-3(n.s)
endopeptidase activityGO:0004175215.38%0.99%7.03E-3(n.s)
malate dehydrogenase activityGO:001661517.69%0.06%8.03E-3(n.s)
acyltransferase activityGO:0008415215.38%1.19%0.01(n.s)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747215.38%1.19%0.01(n.s)
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptorGO:001666817.69%0.09%0.01(n.s)
transferase activity, transferring acyl groupsGO:0016746215.38%1.43%0.01(n.s)
thioredoxin peroxidase activityGO:000837917.69%0.12%0.02(n.s)
oxidoreductase activity, acting on sulfur group of donorsGO:001666717.69%0.19%0.02(n.s)
peroxidase activityGO:000460117.69%0.26%0.03(n.s)
oxidoreductase activity, acting on peroxide as acceptorGO:001668417.69%0.26%0.03(n.s)
ubiquitin-specific protease activityGO:000484317.69%0.26%0.03(n.s)
metalloendopeptidase activityGO:000422217.69%0.31%0.04(n.s)
antioxidant activityGO:001620917.69%0.31%0.04(n.s)
peptidase activityGO:0008233215.38%2.48%0.04(n.s)
electron transporter activityGO:000548917.69%0.34%0.04(n.s)
metallopeptidase activityGO:000823717.69%0.43%0.05(n.s)
cysteine-type peptidase activityGO:000823417.69%0.43%0.05(n.s)
acetyltransferase activityGO:001640717.69%0.71%0.09(n.s)
unfolded protein bindingGO:005108217.69%0.9%0.11(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:001661617.69%1.07%0.13(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:001661417.69%1.18%0.14(n.s)
protein bindingGO:0005515215.38%7.39%0.25(n.s)
transferase activityGO:0016740215.38%10.13%0.39(n.s)
hydrolase activityGO:0016787215.38%11.45%0.45(n.s)
transporter activityGO:000521517.69%6.64%0.59(n.s)
bindingGO:0005488215.38%17.35%0.69(n.s)
molecular_functionGO:00036741292.31%99.44%1(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
pyruvate dehydrogenase complex (sensu Eukaryota)GO:0005967538.46%0.08%1.38E-14(2.23E-11)
pyruvate dehydrogenase complexGO:0045254538.46%0.08%1.38E-14(2.23E-11)
nucleoidGO:0009295538.46%0.36%4.56E-10(7.36E-7)
mitochondrial nucleoidGO:0042645538.46%0.36%4.56E-10(7.36E-7)
mitochondrionGO:00057391292.31%15.78%2.52E-9(4.07E-6)
oxoglutarate dehydrogenase complex (sensu Eukaryota)GO:0009353323.08%0.05%6.38E-9(1.03E-5)
oxoglutarate dehydrogenase complexGO:0045252323.08%0.05%6.38E-9(1.03E-5)
mitochondrial matrixGO:0005759753.85%2.52%8.69E-9(1.4E-5)
protein complexGO:0043234861.54%21.07%1.76E-3(n.s)
cytoplasmGO:00057371292.31%55.64%5.53E-3(n.s)
intracellular membrane-bound organelleGO:00432311292.31%55.65%5.54E-3(n.s)
membrane-bound organelleGO:00432271292.31%55.65%5.54E-3(n.s)
glycine cleavage complexGO:000596017.69%0.06%8.03E-3(n.s)
organelleGO:00432261292.31%60.56%0.01(n.s)
intracellular organelleGO:00432291292.31%60.56%0.01(n.s)
mitochondrial intermembrane spaceGO:000575817.69%0.39%0.05(n.s)
proteasome complex (sensu Eukaryota)GO:000050217.69%0.71%0.09(n.s)
membrane fractionGO:000562417.69%1.22%0.15(n.s)
intracellularGO:00056221292.31%77.03%0.16(n.s)
cell fractionGO:000026717.69%1.72%0.2(n.s)
mitochondrial inner membraneGO:000574317.69%2.43%0.27(n.s)
inner membraneGO:001986617.69%2.43%0.27(n.s)
mitochondrial membraneGO:000574017.69%3.16%0.34(n.s)
cellGO:00056231292.31%83.5%0.34(n.s)
endoplasmic reticulumGO:000578317.69%5.84%0.54(n.s)
organelle membraneGO:003109017.69%8.58%0.69(n.s)
cytosolGO:000582917.69%10.08%0.75(n.s)
membraneGO:001602017.69%15.38%0.89(n.s)
nucleusGO:000563417.69%31.01%0.99(n.s)
cellular_componentGO:00055751292.31%99.61%1(n.s)

 

 

cluster_35 (n = 7)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
response to DNA damage stimulusGO:0006974457.14%2.73%1.75E-5(0.03)
response to endogenous stimulusGO:0009719457.14%2.82%2E-5(0.03)
DNA damage checkpointGO:0000077228.57%0.2%7.82E-5(0.13)
DNA damage response, signal transductionGO:0042770228.57%0.22%9.11E-5(0.15)
lagging strand elongationGO:0006273228.57%0.31%1.9E-4(0.31)
mitochondrial genome maintenanceGO:0000002228.57%0.42%3.49E-4(0.56)
response to stressGO:0006950457.14%6.09%4.09E-4(0.66)
DNA strand elongationGO:0006271228.57%0.46%4.32E-4(0.7)
telomere maintenanceGO:0000723228.57%0.65%8.5E-4(n.s)
cell cycle checkpointGO:0000075228.57%0.73%1.06E-3(n.s)
valyl-tRNA aminoacylationGO:0006438114.29%0.02%**
DNA replication, removal of RNA primerGO:0043137114.29%0.02%**
response to stimulusGO:0050896457.14%8.41%1.41E-3(n.s)
DNA metabolismGO:0006259457.14%8.58%1.52E-3(n.s)
cell organization and biogenesisGO:0016043571.43%17.98%2.84E-3(n.s)
DNA-dependent DNA replicationGO:0006261228.57%1.24%3.06E-3(n.s)
mitochondrion organization and biogenesisGO:0007005228.57%1.47%4.29E-3(n.s)
DNA replicationGO:0006260228.57%1.6%5.02E-3(n.s)
DNA replication checkpointGO:0000076114.29%0.08%5.41E-3(n.s)
DNA replication, synthesis of RNA primerGO:0006269114.29%0.11%7.57E-3(n.s)
regulation of progression through cell cycleGO:0000074228.57%2.14%8.88E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139571.43%23.17%9.11E-3(n.s)
DNA repairGO:0006281228.57%2.32%0.01(n.s)
postreplication repairGO:0006301114.29%0.17%0.01(n.s)
DNA unwindingGO:0006268114.29%0.19%0.01(n.s)
biopolymer metabolismGO:0043283571.43%25.06%0.01(n.s)
telomerase-dependent telomere maintenanceGO:0007004114.29%0.2%0.01(n.s)
organelle organization and biogenesisGO:0006996457.14%15.69%0.01(n.s)
DNA recombinationGO:0006310228.57%2.91%0.02(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001228.57%3.72%0.03(n.s)
chromosome organization and biogenesisGO:0051276228.57%3.9%0.03(n.s)
tRNA aminoacylationGO:0043039114.29%0.46%0.03(n.s)
amino acid activationGO:0043038114.29%0.46%0.03(n.s)
tRNA aminoacylation for protein translationGO:0006418114.29%0.46%0.03(n.s)
nucleotide-excision repairGO:0006289114.29%0.48%0.03(n.s)
meiotic recombinationGO:0007131114.29%0.6%0.04(n.s)
double-strand break repairGO:0006302114.29%0.64%0.04(n.s)
meiosis IGO:0007127114.29%0.85%0.06(n.s)
cell cycleGO:0007049228.57%6.12%0.06(n.s)
tRNA modificationGO:0006400114.29%1.02%0.07(n.s)
cellular physiological processGO:00508757100%71.65%0.1(n.s)
cellular processGO:00099877100%72.29%0.1(n.s)
tRNA metabolismGO:0006399114.29%1.6%0.11(n.s)
regulation of cellular physiological processGO:0051244228.57%8.49%0.11(n.s)
regulation of cellular processGO:0050794228.57%8.52%0.11(n.s)
physiological processGO:00075827100%73.68%0.12(n.s)
regulation of physiological processGO:0050791228.57%8.77%0.12(n.s)
regulation of biological processGO:0050789228.57%8.97%0.12(n.s)
meiotic cell cycleGO:0051321114.29%2%0.13(n.s)
meiosisGO:0007126114.29%2%0.13(n.s)
M phase of meiotic cell cycleGO:0051327114.29%2%0.13(n.s)
cell wall organization and biogenesisGO:0007047114.29%2.17%0.14(n.s)
external encapsulating structure organization and biogenesisGO:0045229114.29%2.17%0.14(n.s)
RNA modificationGO:0009451114.29%2.42%0.16(n.s)
amino acid metabolismGO:0006520114.29%2.82%0.18(n.s)
amino acid and derivative metabolismGO:0006519114.29%3.05%0.2(n.s)
primary metabolismGO:0044238571.43%48.71%0.21(n.s)
amine metabolismGO:0009308114.29%3.38%0.21(n.s)
nitrogen compound metabolismGO:0006807114.29%3.66%0.23(n.s)
establishment of protein localizationGO:0045184114.29%3.95%0.25(n.s)
M phaseGO:0000279114.29%3.98%0.25(n.s)
cellular metabolismGO:0044237571.43%52.12%0.26(n.s)
protein localizationGO:0008104114.29%4.37%0.27(n.s)
metabolismGO:0008152571.43%52.93%0.28(n.s)
organic acid metabolismGO:0006082114.29%4.6%0.28(n.s)
carboxylic acid metabolismGO:0019752114.29%4.6%0.28(n.s)
translationGO:0043037114.29%6.47%0.37(n.s)
RNA metabolismGO:0016070114.29%8.32%0.46(n.s)
biopolymer modificationGO:0043412114.29%9.25%0.49(n.s)
protein biosynthesisGO:0006412114.29%12.16%0.6(n.s)
macromolecule biosynthesisGO:0009059114.29%13.04%0.62(n.s)
establishment of localizationGO:0051234114.29%14.39%0.66(n.s)
localizationGO:0051179114.29%14.82%0.67(n.s)
cellular biosynthesisGO:0044249114.29%17.05%0.73(n.s)
biosynthesisGO:0009058114.29%18.28%0.76(n.s)
cellular protein metabolismGO:0044267114.29%21.7%0.82(n.s)
protein metabolismGO:0019538114.29%22.06%0.83(n.s)
cellular macromolecule metabolismGO:0044260114.29%24.52%0.86(n.s)
macromolecule metabolismGO:0043170114.29%26.04%0.88(n.s)
biological_processGO:00081507100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA bindingGO:0003677457.14%3.18%3.21E-5(0.05)
valine-tRNA ligase activityGO:0004832114.29%0.02%**
nucleic acid bindingGO:0003676457.14%9.87%2.58E-3(n.s)
ribonuclease H activityGO:0004523114.29%0.06%4.33E-3(n.s)
damaged DNA bindingGO:0003684114.29%0.15%0.01(n.s)
single-stranded DNA bindingGO:0003697114.29%0.19%0.01(n.s)
bindingGO:0005488457.14%17.35%0.02(n.s)
endoribonuclease activity, producing 5'-phosphomonoestersGO:0016891114.29%0.29%0.02(n.s)
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersGO:0016893114.29%0.37%0.03(n.s)
endoribonuclease activityGO:0004521114.29%0.42%0.03(n.s)
ligase activity, forming carbon-oxygen bondsGO:0016875114.29%0.56%0.04(n.s)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876114.29%0.56%0.04(n.s)
tRNA ligase activityGO:0004812114.29%0.56%0.04(n.s)
RNA ligase activityGO:0008452114.29%0.57%0.04(n.s)
ligase activity, forming phosphoric ester bondsGO:0016886114.29%0.62%0.04(n.s)
endonuclease activityGO:0004519114.29%0.88%0.06(n.s)
ribonuclease activityGO:0004540114.29%1.55%0.1(n.s)
ligase activityGO:0016874114.29%1.89%0.13(n.s)
protein kinase activityGO:0004672114.29%1.97%0.13(n.s)
nuclease activityGO:0004518114.29%2.15%0.14(n.s)
phosphotransferase activity, alcohol group as acceptorGO:0016773114.29%2.62%0.17(n.s)
kinase activityGO:0016301114.29%3.05%0.2(n.s)
hydrolase activity, acting on ester bondsGO:0016788114.29%4.12%0.26(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772114.29%5.19%0.31(n.s)
catalytic activityGO:0003824342.86%29.21%0.34(n.s)
protein bindingGO:0005515114.29%7.39%0.42(n.s)
transferase activityGO:0016740114.29%10.13%0.53(n.s)
hydrolase activityGO:0016787114.29%11.45%0.57(n.s)
molecular_functionGO:00036747100%99.44%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nucleoidGO:0009295228.57%0.36%2.52E-4(0.41)
mitochondrial nucleoidGO:0042645228.57%0.36%2.52E-4(0.41)
chromosomeGO:0005694342.86%3.16%9.91E-4(n.s)
mitochondrial chromosomeGO:0000262114.29%0.03%2.17E-3(n.s)
DNA replication factor A complexGO:0005662114.29%0.05%3.25E-3(n.s)
mitochondrial matrixGO:0005759228.57%2.52%0.01(n.s)
mitochondrionGO:0005739457.14%15.78%0.01(n.s)
replisomeGO:0030894114.29%0.4%0.03(n.s)
chromosome, telomeric regionGO:0000781114.29%0.4%0.03(n.s)
organelleGO:00432267100%60.56%0.03(n.s)
intracellular organelleGO:00432297100%60.56%0.03(n.s)
replication forkGO:0005657114.29%0.6%0.04(n.s)
intracellular non-membrane-bound organelleGO:0043232342.86%14.3%0.07(n.s)
non-membrane-bound organelleGO:0043228342.86%14.3%0.07(n.s)
intracellular membrane-bound organelleGO:0043231685.71%55.65%0.11(n.s)
membrane-bound organelleGO:0043227685.71%55.65%0.11(n.s)
nuclear chromosomeGO:0000228114.29%2.31%0.15(n.s)
intracellularGO:00056227100%77.03%0.16(n.s)
cellGO:00056237100%83.5%0.28(n.s)
nucleusGO:0005634342.86%31.01%0.38(n.s)
cytoplasmGO:0005737457.14%55.64%0.62(n.s)
protein complexGO:0043234114.29%21.07%0.81(n.s)
cellular_componentGO:00055757100%99.61%0.97(n.s)

 

 

cluster_61 (n = 12)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA metabolismGO:001607012100%8.32%9.79E-14(1.58E-10)
RNA splicingGO:0008380866.67%1.95%7.81E-12(1.26E-8)
Group I intron splicingGO:0000372433.33%0.11%2.39E-10(3.86E-7)
RNA splicing, via transesterification reactions with guanosine as nucleophileGO:0000376433.33%0.11%2.39E-10(3.86E-7)
RNA processingGO:0006396975%5.33%5.97E-10(9.65E-7)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613912100%23.17%2.32E-8(3.74E-5)
biopolymer metabolismGO:004328312100%25.06%5.95E-8(9.62E-5)
RNA splicing, via transesterification reactionsGO:0000375541.67%1.63%7.48E-7(1.21E-3)
mitochondrial transportGO:0006839325%0.17%8.03E-7(1.3E-3)
mitochondrial iron ion transportGO:0048250216.67%0.03%3.17E-6(5.12E-3)
tRNA modificationGO:0006400433.33%1.02%4.64E-6(7.5E-3)
tRNA metabolismGO:0006399433.33%1.6%2.74E-5(0.04)
di-, tri-valent inorganic cation transportGO:0015674325%0.79%9.72E-5(0.16)
metal ion transportGO:0030001325%0.87%1.29E-4(0.21)
RNA modificationGO:0009451433.33%2.42%1.4E-4(0.23)
primary metabolismGO:004423812100%48.71%1.77E-4(0.29)
cellular metabolismGO:004423712100%52.12%3.98E-4(0.64)
metabolismGO:000815212100%52.93%4.79E-4(0.77)
cation transportGO:0006812325%1.36%4.93E-4(0.8)
iron ion transportGO:0006826216.67%0.29%5.32E-4(0.86)
ion transportGO:0006811325%1.64%8.5E-4(n.s)
Group II intron splicingGO:000037318.33%0.02%**
transition metal ion transportGO:0000041216.67%0.67%2.74E-3(n.s)
leucyl-tRNA aminoacylationGO:000642918.33%0.03%3.71E-3(n.s)
mitochondrial magnesium ion transportGO:004501618.33%0.03%3.71E-3(n.s)
magnesium ion transportGO:001569318.33%0.08%9.26E-3(n.s)
protein biosynthesisGO:0006412541.67%12.16%9.97E-3(n.s)
macromolecule biosynthesisGO:0009059541.67%13.04%0.01(n.s)
cellular physiological processGO:005087512100%71.65%0.02(n.s)
biopolymer modificationGO:0043412433.33%9.25%0.02(n.s)
cellular processGO:000998712100%72.29%0.02(n.s)
physiological processGO:000758212100%73.68%0.03(n.s)
cellular biosynthesisGO:0044249541.67%17.05%0.04(n.s)
biosynthesisGO:0009058541.67%18.28%0.05(n.s)
tRNA aminoacylationGO:004303918.33%0.46%0.05(n.s)
amino acid activationGO:004303818.33%0.46%0.05(n.s)
tRNA aminoacylation for protein translationGO:000641818.33%0.46%0.05(n.s)
intracellular transportGO:0046907325%7.53%0.06(n.s)
cellular protein metabolismGO:0044267541.67%21.7%0.1(n.s)
protein metabolismGO:0019538541.67%22.06%0.1(n.s)
cellular macromolecule metabolismGO:0044260541.67%24.52%0.15(n.s)
RNA splicing, via transesterification reactions with bulged adenosine as nucleophileGO:000037718.33%1.52%0.17(n.s)
macromolecule metabolismGO:0043170541.67%26.04%0.18(n.s)
mRNA processingGO:000639718.33%2.03%0.22(n.s)
transportGO:0006810325%14.27%0.24(n.s)
establishment of localizationGO:0051234325%14.39%0.24(n.s)
localizationGO:0051179325%14.82%0.26(n.s)
amino acid metabolismGO:000652018.33%2.82%0.29(n.s)
mRNA metabolismGO:001607118.33%2.85%0.29(n.s)
amino acid and derivative metabolismGO:000651918.33%3.05%0.31(n.s)
amine metabolismGO:000930818.33%3.38%0.34(n.s)
nitrogen compound metabolismGO:000680718.33%3.66%0.36(n.s)
organic acid metabolismGO:000608218.33%4.6%0.43(n.s)
carboxylic acid metabolismGO:001975218.33%4.6%0.43(n.s)
translationGO:004303718.33%6.47%0.55(n.s)
biological_processGO:000815012100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
di-, tri-valent inorganic cation transporter activityGO:0015082325%0.54%3.11E-5(0.05)
metal ion transporter activityGO:0046873325%0.59%3.99E-5(0.06)
iron ion transporter activityGO:0005381216.67%0.15%1.41E-4(0.23)
RNA bindingGO:0003723541.67%5.96%4.1E-4(0.66)
transition metal ion transporter activityGO:0046915216.67%0.42%1.08E-3(n.s)
cation transporter activityGO:0008324325%1.89%1.28E-3(n.s)
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activityGO:000480818.33%0.02%**
ion transporter activityGO:0015075325%2.21%2.02E-3(n.s)
leucine-tRNA ligase activityGO:000482318.33%0.03%3.71E-3(n.s)
nucleic acid bindingGO:0003676541.67%9.87%4.04E-3(n.s)
magnesium ion transporter activityGO:001509518.33%0.05%5.57E-3(n.s)
bindingGO:0005488650%17.35%9.62E-3(n.s)
carrier activityGO:0005386216.67%1.64%0.02(n.s)
GTP bindingGO:000552518.33%0.14%0.02(n.s)
guanyl nucleotide bindingGO:001900118.33%0.15%0.02(n.s)
tRNA methyltransferase activityGO:000817518.33%0.19%0.02(n.s)
endodeoxyribonuclease activityGO:000452018.33%0.28%0.03(n.s)
deoxyribonuclease activityGO:000453618.33%0.31%0.04(n.s)
RNA methyltransferase activityGO:000817318.33%0.31%0.04(n.s)
transporter activityGO:0005215325%6.64%0.04(n.s)
mRNA bindingGO:000372918.33%0.5%0.06(n.s)
purine nucleotide bindingGO:001707618.33%0.5%0.06(n.s)
nucleotide bindingGO:000016618.33%0.51%0.06(n.s)
ligase activity, forming carbon-oxygen bondsGO:001687518.33%0.56%0.06(n.s)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:001687618.33%0.56%0.06(n.s)
tRNA ligase activityGO:000481218.33%0.56%0.06(n.s)
RNA ligase activityGO:000845218.33%0.57%0.07(n.s)
ligase activity, forming phosphoric ester bondsGO:001688618.33%0.62%0.07(n.s)
RNA helicase activityGO:000372418.33%0.64%0.07(n.s)
RNA splicing factor activity, transesterification mechanismGO:003120218.33%0.65%0.08(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:000875718.33%0.77%0.09(n.s)
endonuclease activityGO:000451918.33%0.88%0.1(n.s)
methyltransferase activityGO:000816818.33%1.1%0.12(n.s)
transferase activity, transferring one-carbon groupsGO:001674118.33%1.13%0.13(n.s)
helicase activityGO:000438618.33%1.3%0.15(n.s)
ligase activityGO:001687418.33%1.89%0.2(n.s)
nuclease activityGO:000451818.33%2.15%0.23(n.s)
hydrolase activity, acting on ester bondsGO:001678818.33%4.12%0.4(n.s)
catalytic activityGO:0003824433.33%29.21%0.48(n.s)
transferase activityGO:001674018.33%10.13%0.72(n.s)
hydrolase activityGO:001678718.33%11.45%0.77(n.s)
molecular_functionGO:000367412100%99.44%0.94(n.s)
molecular function unknownGO:0005554216.67%35.75%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:000573912100%15.78%2.26E-10(3.66E-7)
cytoplasmGO:000573712100%55.64%8.73E-4(n.s)
intracellular membrane-bound organelleGO:004323112100%55.65%8.76E-4(n.s)
membrane-bound organelleGO:004322712100%55.65%8.76E-4(n.s)
organelleGO:004322612100%60.56%2.42E-3(n.s)
intracellular organelleGO:004322912100%60.56%2.42E-3(n.s)
mitochondrial inner membraneGO:0005743216.67%2.43%0.03(n.s)
inner membraneGO:0019866216.67%2.43%0.03(n.s)
intracellularGO:000562212100%77.03%0.04(n.s)
mitochondrial membraneGO:0005740216.67%3.16%0.05(n.s)
cellGO:000562312100%83.5%0.11(n.s)
mitochondrial matrixGO:000575918.33%2.52%0.26(n.s)
organelle membraneGO:0031090216.67%8.58%0.28(n.s)
membraneGO:0016020216.67%15.38%0.57(n.s)
cellular_componentGO:000557512100%99.61%0.95(n.s)

 

 

cluster_62 (n = 15)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein biosynthesisGO:00064121280%12.16%3.1E-9(5.02E-6)
macromolecule biosynthesisGO:00090591280%13.04%7.04E-9(1.14E-5)
macromolecule metabolismGO:00431701493.33%26.04%7.2E-8(1.16E-4)
cellular biosynthesisGO:00442491280%17.05%1.58E-7(2.55E-4)
biosynthesisGO:00090581280%18.28%3.49E-7(5.64E-4)
cellular protein metabolismGO:00442671280%21.7%2.46E-6(3.98E-3)
protein metabolismGO:00195381280%22.06%2.96E-6(4.78E-3)
cellular macromolecule metabolismGO:00442601280%24.52%9.7E-6(0.02)
primary metabolismGO:00442381493.33%48.71%3.42E-4(0.55)
cellular metabolismGO:00442371493.33%52.12%8.32E-4(n.s)
metabolismGO:00081521493.33%52.93%1.02E-3(n.s)
positive regulation of translationGO:004594616.67%0.02%**
RNA catabolismGO:0006401213.33%0.99%9.35E-3(n.s)
aerobic respirationGO:0009060213.33%1.27%0.02(n.s)
Group I intron splicingGO:000037216.67%0.11%0.02(n.s)
RNA splicing, via transesterification reactions with guanosine as nucleophileGO:000037616.67%0.11%0.02(n.s)
cellular respirationGO:0045333213.33%1.35%0.02(n.s)
RNA metabolismGO:0016070426.67%8.32%0.03(n.s)
cellular physiological processGO:00508751493.33%71.65%0.05(n.s)
cellular processGO:00099871493.33%72.29%0.05(n.s)
physiological processGO:00075821493.33%73.68%0.06(n.s)
regulation of translationGO:000644516.67%0.45%0.07(n.s)
regulation of protein biosynthesisGO:000641716.67%0.46%0.07(n.s)
energy derivation by oxidation of organic compoundsGO:0015980213.33%3.04%0.07(n.s)
generation of precursor metabolites and energyGO:0006091213.33%3.5%0.1(n.s)
regulation of protein metabolismGO:005124616.67%0.67%0.1(n.s)
regulation of biosynthesisGO:000988916.67%0.71%0.1(n.s)
regulation of cellular biosynthesisGO:003132616.67%0.71%0.1(n.s)
cellular macromolecule catabolismGO:0044265213.33%4.51%0.14(n.s)
macromolecule catabolismGO:0009057213.33%4.83%0.16(n.s)
mitochondrion organization and biogenesisGO:000700516.67%1.47%0.2(n.s)
cellular catabolismGO:0044248213.33%5.84%0.22(n.s)
RNA splicing, via transesterification reactionsGO:000037516.67%1.63%0.22(n.s)
catabolismGO:0009056213.33%6.16%0.24(n.s)
RNA splicingGO:000838016.67%1.95%0.26(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139426.67%23.17%0.47(n.s)
biopolymer metabolismGO:0043283426.67%25.06%0.54(n.s)
RNA processingGO:000639616.67%5.33%0.56(n.s)
regulation of cellular metabolismGO:003132316.67%5.98%0.6(n.s)
regulation of metabolismGO:001922216.67%6.37%0.63(n.s)
translationGO:004303716.67%6.47%0.63(n.s)
regulation of cellular physiological processGO:005124416.67%8.49%0.74(n.s)
regulation of cellular processGO:005079416.67%8.52%0.74(n.s)
regulation of physiological processGO:005079116.67%8.77%0.75(n.s)
regulation of biological processGO:005078916.67%8.97%0.76(n.s)
organelle organization and biogenesisGO:000699616.67%15.69%0.92(n.s)
cell organization and biogenesisGO:001604316.67%17.98%0.95(n.s)
biological process unknownGO:000000416.67%25.64%0.99(n.s)
biological_processGO:000815015100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
translation regulator activityGO:0045182640%0.9%1.9E-9(3.07E-6)
exoribonuclease II activityGO:000885916.67%0.02%**
exoribonuclease activity, producing 5'-phosphomonoestersGO:001689616.67%0.36%0.05(n.s)
exoribonuclease activityGO:000453216.67%0.36%0.05(n.s)
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersGO:001679616.67%0.37%0.05(n.s)
3'-5' exonuclease activityGO:000840816.67%0.39%0.06(n.s)
RNA-dependent ATPase activityGO:000818616.67%0.42%0.06(n.s)
ATP-dependent RNA helicase activityGO:000400416.67%0.42%0.06(n.s)
exonuclease activityGO:000452716.67%0.51%0.07(n.s)
ATP-dependent helicase activityGO:000802616.67%0.57%0.08(n.s)
RNA helicase activityGO:000372416.67%0.64%0.09(n.s)
translation factor activity, nucleic acid bindingGO:000813516.67%0.73%0.1(n.s)
helicase activityGO:000438616.67%1.3%0.18(n.s)
ribonuclease activityGO:000454016.67%1.55%0.21(n.s)
ATPase activity, coupledGO:004262316.67%1.58%0.21(n.s)
molecular function unknownGO:0005554746.67%35.75%0.27(n.s)
nuclease activityGO:000451816.67%2.15%0.28(n.s)
ATPase activityGO:001688716.67%2.52%0.32(n.s)
nucleoside-triphosphatase activityGO:001711116.67%3.42%0.41(n.s)
pyrophosphatase activityGO:001646216.67%3.67%0.43(n.s)
hydrolase activity, acting on acid anhydridesGO:001681716.67%3.69%0.43(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:001681816.67%3.69%0.43(n.s)
nucleic acid bindingGO:0003676213.33%9.87%0.44(n.s)
hydrolase activity, acting on ester bondsGO:001678816.67%4.12%0.47(n.s)
hydrolase activityGO:0016787213.33%11.45%0.53(n.s)
RNA bindingGO:000372316.67%5.96%0.6(n.s)
bindingGO:0005488213.33%17.35%0.76(n.s)
molecular_functionGO:000367415100%99.44%0.92(n.s)
catalytic activityGO:0003824213.33%29.21%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:000573915100%15.78%8.62E-13(1.39E-9)
mitochondrial inner membraneGO:0005743853.33%2.43%5.7E-10(9.22E-7)
inner membraneGO:0019866853.33%2.43%5.7E-10(9.22E-7)
mitochondrial membraneGO:0005740853.33%3.16%4.62E-9(7.46E-6)
organelle membraneGO:0031090853.33%8.58%1.05E-5(0.02)
mitochondrial matrixGO:0005759533.33%2.52%2.36E-5(0.04)
cytoplasmGO:000573715100%55.64%1.5E-4(0.24)
intracellular membrane-bound organelleGO:004323115100%55.65%1.5E-4(0.24)
membrane-bound organelleGO:004322715100%55.65%1.5E-4(0.24)
organelleGO:004322615100%60.56%5.35E-4(0.87)
intracellular organelleGO:004322915100%60.56%5.35E-4(0.87)
membraneGO:0016020853.33%15.38%7.13E-4(n.s)
intracellularGO:000562215100%77.03%0.02(n.s)
cellGO:000562315100%83.5%0.07(n.s)
extrinsic to membraneGO:001989816.67%0.48%0.07(n.s)
organellar ribosomeGO:000031316.67%1.29%0.18(n.s)
mitochondrial ribosomeGO:000576116.67%1.29%0.18(n.s)
integral to membraneGO:001602116.67%3.55%0.42(n.s)
intrinsic to membraneGO:003122416.67%3.61%0.42(n.s)
ribosomeGO:000584016.67%4.4%0.49(n.s)
ribonucleoprotein complexGO:003052916.67%7.19%0.67(n.s)
intracellular non-membrane-bound organelleGO:004323216.67%14.3%0.9(n.s)
non-membrane-bound organelleGO:004322816.67%14.3%0.9(n.s)
cellular_componentGO:000557515100%99.61%0.94(n.s)
protein complexGO:004323416.67%21.07%0.97(n.s)

 

 

cluster_64 (n = 6)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrion organization and biogenesisGO:00070056100%1.47%8.66E-12(1.4E-8)
mitochondrial fissionGO:0000266350%0.05%4.46E-10(7.21E-7)
organelle fissionGO:0048285350%0.05%4.46E-10(7.21E-7)
mitochondrial fusionGO:0008053350%0.06%1.78E-9(2.88E-6)
organelle fusionGO:0048284350%0.26%3.02E-7(4.88E-4)
mitochondrial genome maintenanceGO:0000002350%0.42%1.29E-6(2.09E-3)
organelle organization and biogenesisGO:00069966100%15.69%1.47E-5(0.02)
cell organization and biogenesisGO:00160436100%17.98%3.35E-5(0.05)
filamentous growthGO:0030447116.67%1.32%0.08(n.s)
growthGO:0040007116.67%1.72%0.1(n.s)
cellular physiological processGO:00508756100%71.65%0.14(n.s)
cellular processGO:00099876100%72.29%0.14(n.s)
physiological processGO:00075826100%73.68%0.16(n.s)
transportGO:0006810116.67%14.27%0.6(n.s)
establishment of localizationGO:0051234116.67%14.39%0.61(n.s)
localizationGO:0051179116.67%14.82%0.62(n.s)
biological_processGO:00081506100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
GTPase activityGO:0003924350%0.91%1.42E-5(0.02)
nucleoside-triphosphatase activityGO:0017111350%3.42%7.33E-4(n.s)
pyrophosphatase activityGO:0016462350%3.67%9E-4(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818350%3.69%9.11E-4(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817350%3.69%9.11E-4(n.s)
hydrolase activityGO:0016787350%11.45%0.02(n.s)
catalytic activityGO:0003824350%29.21%0.24(n.s)
transporter activityGO:0005215116.67%6.64%0.34(n.s)
molecular function unknownGO:0005554233.33%35.75%0.69(n.s)
molecular_functionGO:00036746100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial outer membraneGO:0005741583.33%0.53%1.78E-11(2.88E-8)
outer membraneGO:0019867583.33%0.53%1.78E-11(2.88E-8)
mitochondrial membraneGO:0005740583.33%3.16%1.76E-7(2.84E-4)
mitochondrionGO:00057396100%15.78%1.53E-5(0.02)
organelle membraneGO:0031090583.33%8.58%2.55E-5(0.04)
membraneGO:0016020583.33%15.38%4.47E-4(0.72)
mitochondrial intermembrane spaceGO:0005758116.67%0.39%0.02(n.s)
cytoplasmGO:00057376100%55.64%0.03(n.s)
intracellular membrane-bound organelleGO:00432316100%55.65%0.03(n.s)
membrane-bound organelleGO:00432276100%55.65%0.03(n.s)
organelleGO:00432266100%60.56%0.05(n.s)
intracellular organelleGO:00432296100%60.56%0.05(n.s)
intracellularGO:00056226100%77.03%0.21(n.s)
cellGO:00056236100%83.5%0.34(n.s)
cellular_componentGO:00055756100%99.61%0.98(n.s)

 

 

cluster_66 (n = 8)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
amino acid metabolismGO:0006520787.5%2.82%9.87E-11(1.59E-7)
amino acid and derivative metabolismGO:0006519787.5%3.05%1.73E-10(2.79E-7)
amine metabolismGO:0009308787.5%3.38%3.54E-10(5.72E-7)
nitrogen compound metabolismGO:0006807787.5%3.66%6.2E-10(1E-6)
organic acid metabolismGO:0006082787.5%4.6%3.13E-9(5.06E-6)
carboxylic acid metabolismGO:0019752787.5%4.6%3.13E-9(5.06E-6)
seryl-tRNA aminoacylationGO:0006434225%0.03%1.34E-6(2.17E-3)
tRNA aminoacylationGO:0043039337.5%0.46%4.99E-6(8.07E-3)
amino acid activationGO:0043038337.5%0.46%4.99E-6(8.07E-3)
tRNA aminoacylation for protein translationGO:0006418337.5%0.46%4.99E-6(8.07E-3)
threonine metabolismGO:0006566225%0.12%3.75E-5(0.06)
tRNA modificationGO:0006400337.5%1.02%5.51E-5(0.09)
tRNA metabolismGO:0006399337.5%1.6%2.08E-4(0.34)
serine family amino acid metabolismGO:0009069225%0.34%3.07E-4(0.5)
cellular biosynthesisGO:0044249675%17.05%4.98E-4(0.8)
RNA modificationGO:0009451337.5%2.42%7.09E-4(n.s)
biosynthesisGO:0009058675%18.28%7.36E-4(n.s)
threonyl-tRNA aminoacylationGO:0006435112.5%0.02%**
aspartate family amino acid metabolismGO:0009066225%0.7%1.3E-3(n.s)
cysteine biosynthesisGO:0019344112.5%0.03%2.48E-3(n.s)
primary metabolismGO:00442388100%48.71%3.16E-3(n.s)
threonine catabolismGO:0006567112.5%0.05%3.71E-3(n.s)
cysteine metabolismGO:0006534112.5%0.06%4.95E-3(n.s)
cellular metabolismGO:00442378100%52.12%5.43E-3(n.s)
metabolismGO:00081528100%52.93%6.13E-3(n.s)
amino acid biosynthesisGO:0008652225%1.53%6.14E-3(n.s)
serine family amino acid catabolismGO:0009071112.5%0.08%6.18E-3(n.s)
amine biosynthesisGO:0009309225%1.67%7.27E-3(n.s)
nitrogen compound biosynthesisGO:0044271225%1.67%7.27E-3(n.s)
protein biosynthesisGO:0006412450%12.16%0.01(n.s)
sulfur amino acid biosynthesisGO:0000097112.5%0.14%0.01(n.s)
translationGO:0043037337.5%6.47%0.01(n.s)
aspartate family amino acid catabolismGO:0009068112.5%0.15%0.01(n.s)
macromolecule biosynthesisGO:0009059450%13.04%0.01(n.s)
serine family amino acid biosynthesisGO:0009070112.5%0.19%0.01(n.s)
branched chain family amino acid biosynthesisGO:0009082112.5%0.2%0.02(n.s)
sulfur compound biosynthesisGO:0044272112.5%0.23%0.02(n.s)
branched chain family amino acid metabolismGO:0009081112.5%0.25%0.02(n.s)
RNA metabolismGO:0016070337.5%8.32%0.02(n.s)
biopolymer modificationGO:0043412337.5%9.25%0.03(n.s)
amino acid catabolismGO:0009063112.5%0.43%0.03(n.s)
invasive growth (sensu Saccharomyces)GO:0001403112.5%0.46%0.04(n.s)
amine catabolismGO:0009310112.5%0.48%0.04(n.s)
nitrogen compound catabolismGO:0044270112.5%0.48%0.04(n.s)
sulfur amino acid metabolismGO:0000096112.5%0.5%0.04(n.s)
pseudohyphal growthGO:0007124112.5%0.74%0.06(n.s)
sulfur metabolismGO:0006790112.5%0.87%0.07(n.s)
cellular physiological processGO:00508758100%71.65%0.07(n.s)
cellular protein metabolismGO:0044267450%21.7%0.07(n.s)
cellular processGO:00099878100%72.29%0.07(n.s)
protein metabolismGO:0019538450%22.06%0.08(n.s)
endocytosisGO:0006897112.5%1.07%0.08(n.s)
physiological processGO:00075828100%73.68%0.09(n.s)
aerobic respirationGO:0009060112.5%1.27%0.1(n.s)
filamentous growthGO:0030447112.5%1.32%0.1(n.s)
cellular respirationGO:0045333112.5%1.35%0.1(n.s)
cellular macromolecule metabolismGO:0044260450%24.52%0.11(n.s)
macromolecule metabolismGO:0043170450%26.04%0.13(n.s)
growthGO:0040007112.5%1.72%0.13(n.s)
energy derivation by oxidation of organic compoundsGO:0015980112.5%3.04%0.22(n.s)
generation of precursor metabolites and energyGO:0006091112.5%3.5%0.25(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139337.5%23.17%0.28(n.s)
vesicle-mediated transportGO:0016192112.5%4.34%0.3(n.s)
biopolymer metabolismGO:0043283337.5%25.06%0.32(n.s)
cellular catabolismGO:0044248112.5%5.84%0.38(n.s)
catabolismGO:0009056112.5%6.16%0.4(n.s)
transportGO:0006810112.5%14.27%0.71(n.s)
establishment of localizationGO:0051234112.5%14.39%0.71(n.s)
localizationGO:0051179112.5%14.82%0.72(n.s)
biological_processGO:00081508100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ligase activity, forming carbon-oxygen bondsGO:0016875450%0.56%5.61E-8(9.07E-5)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876450%0.56%5.61E-8(9.07E-5)
tRNA ligase activityGO:0004812450%0.56%5.61E-8(9.07E-5)
RNA ligase activityGO:0008452450%0.57%6.29E-8(1.02E-4)
ligase activity, forming phosphoric ester bondsGO:0016886450%0.62%8.69E-8(1.4E-4)
serine-tRNA ligase activityGO:0004828225%0.03%1.34E-6(2.17E-3)
threonine-tRNA ligase activityGO:0004829225%0.03%1.34E-6(2.17E-3)
threonine ammonia-lyase activityGO:0004794225%0.03%1.34E-6(2.17E-3)
lyase activityGO:0016829450%1.27%1.63E-6(2.63E-3)
ligase activityGO:0016874450%1.89%8.02E-6(0.01)
ammonia-lyase activityGO:0016841225%0.06%8.05E-6(0.01)
carbon-nitrogen lyase activityGO:0016840225%0.09%2.01E-5(0.03)
catalytic activityGO:00038248100%29.21%5.25E-5(0.08)
carbon-oxygen lyase activityGO:0016835225%0.56%8.29E-4(n.s)
threonine synthase activityGO:0004795112.5%0.02%**
cystathionine beta-synthase activityGO:0004122112.5%0.02%**
L-serine ammonia-lyase activityGO:0003941112.5%0.03%2.48E-3(n.s)
carbon-oxygen lyase activity, acting on phosphatesGO:0016838112.5%0.05%3.71E-3(n.s)
hydro-lyase activityGO:0016836112.5%0.43%0.03(n.s)
molecular_functionGO:00036748100%99.44%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739675%15.78%3.2E-4(0.52)
cytoplasmGO:00057378100%55.64%9.15E-3(n.s)
nucleoidGO:0009295112.5%0.36%0.03(n.s)
mitochondrial nucleoidGO:0042645112.5%0.36%0.03(n.s)
intracellular membrane-bound organelleGO:0043231787.5%55.65%0.07(n.s)
membrane-bound organelleGO:0043227787.5%55.65%0.07(n.s)
organelleGO:0043226787.5%60.56%0.11(n.s)
intracellular organelleGO:0043229787.5%60.56%0.11(n.s)
intracellularGO:00056228100%77.03%0.12(n.s)
mitochondrial matrixGO:0005759112.5%2.52%0.19(n.s)
cellGO:00056238100%83.5%0.24(n.s)
nucleusGO:0005634112.5%31.01%0.95(n.s)
cellular_componentGO:00055758100%99.61%0.97(n.s)

 

 

cluster_69 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
copper ion transportGO:0006825480%0.2%4.94E-11(7.98E-8)
transition metal ion transportGO:0000041480%0.67%8.49E-9(1.37E-5)
di-, tri-valent inorganic cation transportGO:0015674480%0.79%1.72E-8(2.78E-5)
metal ion transportGO:0030001480%0.87%2.52E-8(4.08E-5)
cation transportGO:0006812480%1.36%1.6E-7(2.58E-4)
ion transportGO:0006811480%1.64%3.39E-7(5.48E-4)
protein complex assemblyGO:0006461480%2.26%1.23E-6(1.99E-3)
intracellular copper ion transportGO:0015680240%0.09%7.19E-6(0.01)
redox signal responseGO:0006980120%0.02%**
transportGO:0006810480%14.27%1.83E-3(n.s)
establishment of localizationGO:0051234480%14.39%1.89E-3(n.s)
localizationGO:0051179480%14.82%2.12E-3(n.s)
heme a metabolismGO:0046160120%0.06%3.1E-3(n.s)
heme a biosynthesisGO:0006784120%0.06%3.1E-3(n.s)
cytochrome c oxidase complex assemblyGO:0008535120%0.14%6.95E-3(n.s)
cellular protein metabolismGO:0044267480%21.7%9.14E-3(n.s)
protein metabolismGO:0019538480%22.06%9.72E-3(n.s)
pigment biosynthesisGO:0046148120%0.22%0.01(n.s)
porphyrin biosynthesisGO:0006779120%0.22%0.01(n.s)
heme biosynthesisGO:0006783120%0.22%0.01(n.s)
porphyrin metabolismGO:0006778120%0.23%0.01(n.s)
heme metabolismGO:0042168120%0.23%0.01(n.s)
pigment metabolismGO:0042440120%0.23%0.01(n.s)
secondary metabolismGO:0019748120%0.28%0.01(n.s)
cellular macromolecule metabolismGO:0044260480%24.52%0.01(n.s)
macromolecule metabolismGO:0043170480%26.04%0.02(n.s)
response to oxidative stressGO:0006979120%0.79%0.04(n.s)
oxygen and reactive oxygen species metabolismGO:0006800120%0.82%0.04(n.s)
intracellular transportGO:0046907240%7.53%0.05(n.s)
cofactor biosynthesisGO:0051188120%1.08%0.05(n.s)
response to biotic stimulusGO:0009607120%1.08%0.05(n.s)
heterocycle metabolismGO:0046483120%1.1%0.05(n.s)
aerobic respirationGO:0009060120%1.27%0.06(n.s)
cellular respirationGO:0045333120%1.35%0.07(n.s)
cofactor metabolismGO:0051186120%2.26%0.11(n.s)
energy derivation by oxidation of organic compoundsGO:0015980120%3.04%0.14(n.s)
generation of precursor metabolites and energyGO:0006091120%3.5%0.16(n.s)
primary metabolismGO:0044238480%48.71%0.17(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
cellular metabolismGO:0044237480%52.12%0.22(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
metabolismGO:0008152480%52.93%0.23(n.s)
response to stressGO:0006950120%6.09%0.27(n.s)
response to stimulusGO:0050896120%8.41%0.36(n.s)
cellular biosynthesisGO:0044249120%17.05%0.61(n.s)
biosynthesisGO:0009058120%18.28%0.64(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
thioredoxin peroxidase activityGO:0008379360%0.12%1.25E-8(2.02E-5)
peroxidase activityGO:0004601360%0.26%1.51E-7(2.44E-4)
oxidoreductase activity, acting on peroxide as acceptorGO:0016684360%0.26%1.51E-7(2.44E-4)
antioxidant activityGO:0016209360%0.31%2.53E-7(4.09E-4)
copper ion bindingGO:0005507240%0.08%4.79E-6(7.75E-3)
transition metal ion bindingGO:0046914240%0.12%1.34E-5(0.02)
cation bindingGO:0043169240%0.19%3.16E-5(0.05)
metal ion bindingGO:0046872240%0.25%5.73E-5(0.09)
ion bindingGO:0043167240%0.25%5.73E-5(0.09)
oxidoreductase activityGO:0016491360%3.73%4.86E-4(0.79)
protoheme IX farnesyltransferase activityGO:0008495120%0.02%**
copper chaperone activityGO:0016531120%0.05%2.32E-3(n.s)
farnesyltranstransferase activityGO:0004311120%0.05%2.32E-3(n.s)
metallochaperone activityGO:0016530120%0.06%3.1E-3(n.s)
copper ion transporter activityGO:0005375120%0.09%4.64E-3(n.s)
prenyltransferase activityGO:0004659120%0.2%0.01(n.s)
transition metal ion transporter activityGO:0046915120%0.42%0.02(n.s)
transferase activity, transferring alkyl or aryl (other than methyl) groupsGO:0016765120%0.53%0.03(n.s)
di-, tri-valent inorganic cation transporter activityGO:0015082120%0.54%0.03(n.s)
catalytic activityGO:0003824480%29.21%0.03(n.s)
metal ion transporter activityGO:0046873120%0.59%0.03(n.s)
cation transporter activityGO:0008324120%1.89%0.09(n.s)
ion transporter activityGO:0015075120%2.21%0.11(n.s)
bindingGO:0005488240%17.35%0.21(n.s)
transporter activityGO:0005215120%6.64%0.29(n.s)
transferase activityGO:0016740120%10.13%0.41(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial membraneGO:0005740480%3.16%4.72E-6(7.63E-3)
mitochondrionGO:00057395100%15.78%9.72E-5(0.16)
mitochondrial inner membraneGO:0005743360%2.43%1.36E-4(0.22)
inner membraneGO:0019866360%2.43%1.36E-4(0.22)
organelle membraneGO:0031090480%8.58%2.5E-4(0.4)
membraneGO:0016020480%15.38%2.44E-3(n.s)
mitochondrial intermembrane spaceGO:0005758120%0.39%0.02(n.s)
cytoplasmGO:00057375100%55.64%0.05(n.s)
intracellular membrane-bound organelleGO:00432315100%55.65%0.05(n.s)
membrane-bound organelleGO:00432275100%55.65%0.05(n.s)
organellar ribosomeGO:0000313120%1.29%0.06(n.s)
mitochondrial ribosomeGO:0005761120%1.29%0.06(n.s)
organelleGO:00432265100%60.56%0.08(n.s)
intracellular organelleGO:00432295100%60.56%0.08(n.s)
mitochondrial matrixGO:0005759120%2.52%0.12(n.s)
ribosomeGO:0005840120%4.4%0.2(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
ribonucleoprotein complexGO:0030529120%7.19%0.31(n.s)
cellGO:00056235100%83.5%0.41(n.s)
cytosolGO:0005829120%10.08%0.41(n.s)
intracellular non-membrane-bound organelleGO:0043232120%14.3%0.54(n.s)
non-membrane-bound organelleGO:0043228120%14.3%0.54(n.s)
protein complexGO:0043234120%21.07%0.69(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_6 (n = 9)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrion organization and biogenesisGO:0007005666.67%1.47%7.02E-10(1.13E-6)
mitochondrion inheritanceGO:0000001444.44%0.39%2.18E-8(3.52E-5)
mitochondrion distributionGO:0048311444.44%0.39%2.18E-8(3.52E-5)
organelle inheritanceGO:0048308444.44%0.57%1.13E-7(1.82E-4)
negative regulation of proteolysis and peptidolysisGO:0045861222.22%0.03%1.73E-6(2.79E-3)
negative regulation of catabolismGO:0009895222.22%0.05%5.18E-6(8.37E-3)
negative regulation of protein catabolismGO:0042177222.22%0.05%5.18E-6(8.37E-3)
regulation of proteolysis and peptidolysisGO:0030162222.22%0.06%1.04E-5(0.02)
regulation of protein catabolismGO:0042176222.22%0.08%1.72E-5(0.03)
negative regulation of protein metabolismGO:0051248222.22%0.14%6.19E-5(0.1)
regulation of catabolismGO:0009894222.22%0.25%2.05E-4(0.33)
mitochondrial genome maintenanceGO:0000002222.22%0.42%5.96E-4(0.96)
organelle organization and biogenesisGO:0006996666.67%15.69%8.06E-4(n.s)
replicative cell agingGO:0001302222.22%0.51%8.92E-4(n.s)
cell agingGO:0007569222.22%0.64%1.38E-3(n.s)
agingGO:0007568222.22%0.65%1.45E-3(n.s)
regulation of protein metabolismGO:0051246222.22%0.67%1.51E-3(n.s)
cell organization and biogenesisGO:0016043666.67%17.98%1.71E-3(n.s)
cell deathGO:0008219222.22%0.71%1.73E-3(n.s)
deathGO:0016265222.22%0.73%1.81E-3(n.s)
protein foldingGO:0006457222.22%1.04%3.64E-3(n.s)
negative regulation of cellular metabolismGO:0031324222.22%2.29%0.02(n.s)
negative regulation of metabolismGO:0009892222.22%2.4%0.02(n.s)
proteolysis and peptidolysisGO:0006508222.22%2.42%0.02(n.s)
cellular protein catabolismGO:0044257222.22%2.42%0.02(n.s)
negative regulation of cellular physiological processGO:0051243222.22%2.59%0.02(n.s)
negative regulation of cellular processGO:0048523222.22%2.59%0.02(n.s)
negative regulation of physiological processGO:0043118222.22%2.62%0.02(n.s)
negative regulation of biological processGO:0048519222.22%2.71%0.02(n.s)
protein catabolismGO:0030163222.22%2.74%0.02(n.s)
biopolymer catabolismGO:0043285222.22%2.93%0.03(n.s)
cellular macromolecule catabolismGO:0044265222.22%4.51%0.06(n.s)
macromolecule catabolismGO:0009057222.22%4.83%0.07(n.s)
developmentGO:0007275222.22%5.73%0.09(n.s)
cellular catabolismGO:0044248222.22%5.84%0.09(n.s)
regulation of cellular metabolismGO:0031323222.22%5.98%0.1(n.s)
catabolismGO:0009056222.22%6.16%0.1(n.s)
regulation of metabolismGO:0019222222.22%6.37%0.11(n.s)
regulation of cellular physiological processGO:0051244222.22%8.49%0.17(n.s)
regulation of cellular processGO:0050794222.22%8.52%0.18(n.s)
regulation of physiological processGO:0050791222.22%8.77%0.18(n.s)
protein complex assemblyGO:0006461111.11%2.26%0.19(n.s)
regulation of biological processGO:0050789222.22%8.97%0.19(n.s)
cellular physiological processGO:0050875888.89%71.65%0.23(n.s)
cellular processGO:0009987888.89%72.29%0.24(n.s)
physiological processGO:0007582888.89%73.68%0.27(n.s)
cellular protein metabolismGO:0044267333.33%21.7%0.31(n.s)
protein metabolismGO:0019538333.33%22.06%0.32(n.s)
cellular macromolecule metabolismGO:0044260333.33%24.52%0.39(n.s)
macromolecule metabolismGO:0043170333.33%26.04%0.43(n.s)
biopolymer metabolismGO:0043283222.22%25.06%0.7(n.s)
primary metabolismGO:0044238333.33%48.71%0.9(n.s)
cellular metabolismGO:0044237333.33%52.12%0.93(n.s)
biological process unknownGO:0000004111.11%25.64%0.93(n.s)
metabolismGO:0008152333.33%52.93%0.94(n.s)
biological_processGO:00081509100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055549100%35.75%9.44E-5(0.15)
molecular_functionGO:00036749100%99.44%0.95(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial membraneGO:0005740888.89%3.16%7.61E-12(1.23E-8)
organelle membraneGO:0031090888.89%8.58%2.34E-8(3.77E-5)
mitochondrionGO:00057399100%15.78%5.9E-8(9.54E-5)
mitochondrial outer membraneGO:0005741444.44%0.53%7.93E-8(1.28E-4)
outer membraneGO:0019867444.44%0.53%7.93E-8(1.28E-4)
membraneGO:0016020888.89%15.38%2.38E-6(3.84E-3)
mitochondrial inner membraneGO:0005743444.44%2.43%3.86E-5(0.06)
inner membraneGO:0019866444.44%2.43%3.86E-5(0.06)
cytoplasmGO:00057379100%55.64%5.09E-3(n.s)
intracellular membrane-bound organelleGO:00432319100%55.65%5.1E-3(n.s)
membrane-bound organelleGO:00432279100%55.65%5.1E-3(n.s)
mitochondrial sorting and assembly machinery complexGO:0001401111.11%0.06%5.57E-3(n.s)
organelleGO:00432269100%60.56%0.01(n.s)
intracellular organelleGO:00432299100%60.56%0.01(n.s)
intracellularGO:00056229100%77.03%0.1(n.s)
membrane fractionGO:0005624111.11%1.22%0.1(n.s)
cell fractionGO:0000267111.11%1.72%0.14(n.s)
cellGO:00056239100%83.5%0.2(n.s)
protein complexGO:0043234111.11%21.07%0.88(n.s)
nucleusGO:0005634111.11%31.01%0.96(n.s)
cellular_componentGO:00055759100%99.61%0.97(n.s)

 

 

cluster_99 (n = 38)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein biosynthesisGO:00064123284.21%12.16%3.97E-24(6.42E-21)
macromolecule biosynthesisGO:00090593284.21%13.04%3.69E-23(5.96E-20)
cellular biosynthesisGO:00442493284.21%17.05%1.72E-19(2.79E-16)
biosynthesisGO:00090583284.21%18.28%1.5E-18(2.42E-15)
cellular protein metabolismGO:00442673386.84%21.7%1.49E-17(2.4E-14)
protein metabolismGO:00195383386.84%22.06%2.5E-17(4.05E-14)
macromolecule metabolismGO:00431703489.47%26.04%2.47E-16(3.99E-13)
cellular macromolecule metabolismGO:00442603386.84%24.52%7.33E-16(1.18E-12)
primary metabolismGO:00442383592.11%48.71%1.33E-8(2.15E-5)
cellular metabolismGO:00442373592.11%52.12%1.18E-7(1.91E-4)
metabolismGO:00081523592.11%52.93%1.93E-7(3.12E-4)
cellular physiological processGO:00508753592.11%71.65%2E-3(n.s)
cellular processGO:00099873592.11%72.29%2.57E-3(n.s)
physiological processGO:00075823592.11%73.68%4.37E-3(n.s)
aerobic respirationGO:000906037.89%1.27%0.01(n.s)
cellular respirationGO:004533337.89%1.35%0.01(n.s)
tRNA catabolismGO:001607812.63%0.06%0.02(n.s)
snoRNA catabolismGO:001607712.63%0.06%0.02(n.s)
rRNA catabolismGO:001607512.63%0.06%0.02(n.s)
DNA topological changeGO:000626512.63%0.08%0.03(n.s)
translational initiationGO:000641325.26%0.74%0.03(n.s)
mitotic chromosome condensationGO:000707612.63%0.14%0.05(n.s)
fatty acid beta-oxidationGO:000663512.63%0.14%0.05(n.s)
chromosome condensationGO:003026112.63%0.17%0.06(n.s)
fatty acid oxidationGO:001939512.63%0.17%0.06(n.s)
snoRNA metabolismGO:001607412.63%0.19%0.07(n.s)
ribosomal small subunit assembly and maintenanceGO:000002812.63%0.2%0.07(n.s)
protein deubiquitinationGO:001657912.63%0.28%0.1(n.s)
mitotic sister chromatid cohesionGO:000706412.63%0.29%0.11(n.s)
energy derivation by oxidation of organic compoundsGO:001598037.89%3.04%0.11(n.s)
generation of precursor metabolites and energyGO:000609137.89%3.5%0.15(n.s)
sister chromatid cohesionGO:000706212.63%0.43%0.15(n.s)
telomeric heterochromatin formationGO:003150912.63%0.67%0.22(n.s)
fatty acid metabolismGO:000663112.63%0.67%0.22(n.s)
chromatin silencing at telomereGO:000634812.63%0.67%0.22(n.s)
ribosomal subunit assemblyGO:004225712.63%0.81%0.27(n.s)
sister chromatid segregationGO:000081912.63%0.85%0.28(n.s)
mitotic sister chromatid segregationGO:000007012.63%0.85%0.28(n.s)
RNA catabolismGO:000640112.63%0.99%0.32(n.s)
ribosome assemblyGO:004225512.63%0.99%0.32(n.s)
endocytosisGO:000689712.63%1.07%0.34(n.s)
ubiquitin cycleGO:000651212.63%1.07%0.34(n.s)
negative regulation of gene expression, epigeneticGO:004581412.63%1.19%0.37(n.s)
chromatin silencingGO:000634212.63%1.19%0.37(n.s)
gene silencingGO:001645812.63%1.19%0.37(n.s)
heterochromatin formationGO:003150712.63%1.19%0.37(n.s)
regulation of gene expression, epigeneticGO:004002912.63%1.27%0.39(n.s)
chromatin assemblyGO:003149712.63%1.27%0.39(n.s)
chromosome organization and biogenesisGO:005127625.26%3.9%0.44(n.s)
chromatin assembly or disassemblyGO:000633312.63%1.52%0.44(n.s)
chromosome segregationGO:000705912.63%1.6%0.46(n.s)
tRNA metabolismGO:000639912.63%1.6%0.46(n.s)
negative regulation of transcription, DNA-dependentGO:004589212.63%1.89%0.52(n.s)
negative regulation of transcriptionGO:001648112.63%1.95%0.53(n.s)
chromatin remodelingGO:000633812.63%2.01%0.54(n.s)
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:004593412.63%2.11%0.56(n.s)
mitosisGO:000706712.63%2.26%0.58(n.s)
protein complex assemblyGO:000646112.63%2.26%0.58(n.s)
negative regulation of cellular metabolismGO:003132412.63%2.29%0.59(n.s)
M phase of mitotic cell cycleGO:000008712.63%2.29%0.59(n.s)
negative regulation of metabolismGO:000989212.63%2.4%0.6(n.s)
negative regulation of cellular physiological processGO:005124312.63%2.59%0.63(n.s)
negative regulation of cellular processGO:004852312.63%2.59%0.63(n.s)
negative regulation of physiological processGO:004311812.63%2.62%0.64(n.s)
negative regulation of biological processGO:004851912.63%2.71%0.65(n.s)
chromatin modificationGO:001656812.63%2.77%0.66(n.s)
DNA packagingGO:000632312.63%3.14%0.7(n.s)
establishment and/or maintenance of chromatin architectureGO:000632512.63%3.14%0.7(n.s)
cellular lipid metabolismGO:004425512.63%3.16%0.71(n.s)
translationGO:004303725.26%6.47%0.72(n.s)
lipid metabolismGO:000662912.63%3.38%0.73(n.s)
protein modificationGO:000646425.26%6.68%0.73(n.s)
mitotic cell cycleGO:000027812.63%3.59%0.75(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:000700112.63%3.72%0.76(n.s)
cytoplasm organization and biogenesisGO:000702812.63%3.9%0.78(n.s)
ribosome biogenesis and assemblyGO:004225412.63%3.9%0.78(n.s)
rRNA metabolismGO:001607212.63%3.92%0.78(n.s)
M phaseGO:000027912.63%3.98%0.79(n.s)
vesicle-mediated transportGO:001619212.63%4.34%0.82(n.s)
cellular macromolecule catabolismGO:004426512.63%4.51%0.83(n.s)
organic acid metabolismGO:000608212.63%4.6%0.83(n.s)
carboxylic acid metabolismGO:001975212.63%4.6%0.83(n.s)
regulation of transcription, DNA-dependentGO:000635512.63%4.68%0.84(n.s)
macromolecule catabolismGO:000905712.63%4.83%0.85(n.s)
DNA metabolismGO:000625925.26%8.58%0.85(n.s)
regulation of transcriptionGO:004544912.63%4.96%0.86(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:001921912.63%5.24%0.87(n.s)
biopolymer modificationGO:004341225.26%9.25%0.88(n.s)
developmentGO:000727512.63%5.73%0.89(n.s)
cellular catabolismGO:004424812.63%5.84%0.9(n.s)
regulation of cellular metabolismGO:003132312.63%5.98%0.9(n.s)
cell cycleGO:000704912.63%6.12%0.91(n.s)
catabolismGO:000905612.63%6.16%0.91(n.s)
regulation of metabolismGO:001922212.63%6.37%0.92(n.s)
transcription, DNA-dependentGO:000635112.63%6.78%0.93(n.s)
transcriptionGO:000635012.63%7.43%0.95(n.s)
organelle organization and biogenesisGO:000699637.89%15.69%0.95(n.s)
RNA metabolismGO:001607012.63%8.32%0.96(n.s)
regulation of cellular physiological processGO:005124412.63%8.49%0.97(n.s)
regulation of cellular processGO:005079412.63%8.52%0.97(n.s)
regulation of physiological processGO:005079112.63%8.77%0.97(n.s)
regulation of biological processGO:005078912.63%8.97%0.97(n.s)
cell organization and biogenesisGO:001604337.89%17.98%0.98(n.s)
biological_processGO:000815038100%99.98%0.99(n.s)
transportGO:000681012.63%14.27%1(n.s)
establishment of localizationGO:005123412.63%14.39%1(n.s)
localizationGO:005117912.63%14.82%1(n.s)
biopolymer metabolismGO:004328337.89%25.06%1(n.s)
biological process unknownGO:000000437.89%25.64%1(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613925.26%23.17%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
structural constituent of ribosomeGO:00037353284.21%3.58%1.36E-41(2.2E-38)
structural molecule activityGO:00051983284.21%5.51%2.8E-35(4.53E-32)
3-hydroxyisobutyryl-CoA hydrolase activityGO:000386012.63%0.02%**
CoA hydrolase activityGO:001628912.63%0.05%0.02(n.s)
polynucleotide adenylyltransferase activityGO:000465212.63%0.05%0.02(n.s)
tRNA bindingGO:000004912.63%0.06%0.02(n.s)
thiolester hydrolase activityGO:001679012.63%0.08%0.03(n.s)
ubiquitin-specific protease activityGO:000484312.63%0.26%0.1(n.s)
cysteine-type peptidase activityGO:000823412.63%0.43%0.15(n.s)
carboxylic ester hydrolase activityGO:001678912.63%0.46%0.16(n.s)
DNA-directed DNA polymerase activityGO:000388712.63%1.05%0.33(n.s)
hydrolase activity, acting on ester bondsGO:001678825.26%4.12%0.47(n.s)
nucleotidyltransferase activityGO:001677912.63%1.91%0.52(n.s)
peptidase activityGO:000823312.63%2.48%0.62(n.s)
RNA bindingGO:000372325.26%5.96%0.67(n.s)
molecular_functionGO:000367438100%99.44%0.81(n.s)
hydrolase activityGO:001678737.89%11.45%0.83(n.s)
transferase activity, transferring phosphorus-containing groupsGO:001677212.63%5.19%0.87(n.s)
nucleic acid bindingGO:000367625.26%9.87%0.9(n.s)
transferase activityGO:001674012.63%10.13%0.98(n.s)
bindingGO:000548825.26%17.35%0.99(n.s)
catalytic activityGO:0003824410.53%29.21%1(n.s)
molecular function unknownGO:000555437.89%35.75%1(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial small ribosomal subunitGO:00057633284.21%0.54%6.17E-77(9.98E-74)
organellar small ribosomal subunitGO:00003143284.21%0.54%6.17E-77(9.98E-74)
organellar ribosomeGO:00003133284.21%1.29%8.73E-58(1.41E-54)
mitochondrial ribosomeGO:00057613284.21%1.29%8.73E-58(1.41E-54)
small ribosomal subunitGO:00159353284.21%1.52%5.86E-55(9.47E-52)
mitochondrial matrixGO:00057593284.21%2.52%7.54E-47(1.22E-43)
ribosomeGO:00058403284.21%4.4%1.49E-38(2.4E-35)
ribonucleoprotein complexGO:00305293284.21%7.19%1.71E-31(2.77E-28)
mitochondrionGO:00057393694.74%15.78%4.1E-27(6.63E-24)
intracellular non-membrane-bound organelleGO:00432323284.21%14.3%6.75E-22(1.09E-18)
non-membrane-bound organelleGO:00432283284.21%14.3%6.75E-22(1.09E-18)
protein complexGO:00432343386.84%21.07%5.73E-18(9.26E-15)
intracellular membrane-bound organelleGO:004323138100%55.65%1.95E-10(3.16E-7)
membrane-bound organelleGO:004322738100%55.65%1.95E-10(3.16E-7)
organelleGO:004322638100%60.56%4.93E-9(7.97E-6)
intracellular organelleGO:004322938100%60.56%4.93E-9(7.97E-6)
cytoplasmGO:00057373694.74%55.64%9.43E-8(1.52E-4)
intracellularGO:000562238100%77.03%4.77E-5(0.08)
cellGO:000562338100%83.5%1.04E-3(n.s)
TRAMP complexGO:003149912.63%0.06%0.02(n.s)
cellular_componentGO:000557538100%99.61%0.86(n.s)
nucleusGO:000563425.26%31.01%1(n.s)

 

 

cluster_98 (n = 11)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tRNA processingGO:000803311100%0.53%1.42E-26(2.29E-23)
tRNA metabolismGO:000639911100%1.6%9.89E-21(1.6E-17)
RNA processingGO:000639611100%5.33%8.44E-15(1.36E-11)
rRNA processingGO:0006364981.82%2.71%3.38E-13(5.47E-10)
RNA metabolismGO:001607011100%8.32%1.2E-12(1.94E-9)
ribosome biogenesisGO:0007046981.82%3.3%2.04E-12(3.29E-9)
cytoplasm organization and biogenesisGO:0007028981.82%3.9%9.4E-12(1.52E-8)
ribosome biogenesis and assemblyGO:0042254981.82%3.9%9.4E-12(1.52E-8)
rRNA metabolismGO:0016072981.82%3.92%9.74E-12(1.57E-8)
organelle organization and biogenesisGO:00069961090.91%15.69%8.23E-8(1.33E-4)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613911100%23.17%1.01E-7(1.62E-4)
biopolymer metabolismGO:004328311100%25.06%2.39E-7(3.86E-4)
cell organization and biogenesisGO:00160431090.91%17.98%3.16E-7(5.1E-4)
primary metabolismGO:004423811100%48.71%3.63E-4(0.59)
cellular metabolismGO:004423711100%52.12%7.65E-4(n.s)
metabolismGO:000815211100%52.93%9.06E-4(n.s)
tRNA 5'-leader removalGO:000168219.09%0.02%**
cellular physiological processGO:005087511100%71.65%0.03(n.s)
cellular processGO:000998711100%72.29%0.03(n.s)
physiological processGO:000758211100%73.68%0.03(n.s)
mitochondrion organization and biogenesisGO:000700519.09%1.47%0.15(n.s)
protein biosynthesisGO:000641219.09%12.16%0.76(n.s)
macromolecule biosynthesisGO:000905919.09%13.04%0.79(n.s)
cellular biosynthesisGO:004424919.09%17.05%0.87(n.s)
biosynthesisGO:000905819.09%18.28%0.89(n.s)
cellular protein metabolismGO:004426719.09%21.7%0.93(n.s)
protein metabolismGO:001953819.09%22.06%0.94(n.s)
cellular macromolecule metabolismGO:004426019.09%24.52%0.95(n.s)
macromolecule metabolismGO:004317019.09%26.04%0.96(n.s)
biological_processGO:000815011100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribonuclease P activityGO:00045261090.91%0.19%2.11E-29(3.41E-26)
tRNA-specific ribonuclease activityGO:00045491090.91%0.25%2.56E-27(4.13E-24)
endoribonuclease activity, producing 5'-phosphomonoestersGO:00168911090.91%0.29%2.95E-26(4.76E-23)
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersGO:00168931090.91%0.37%6.25E-25(1.01E-21)
endoribonuclease activityGO:00045211090.91%0.42%2.69E-24(4.35E-21)
ribonuclease MRP activityGO:0000171872.73%0.15%9.95E-23(1.61E-19)
endonuclease activityGO:00045191090.91%0.88%1.37E-20(2.22E-17)
ribonuclease activityGO:00045401090.91%1.55%5.46E-18(8.83E-15)
nuclease activityGO:00045181090.91%2.15%1.67E-16(2.7E-13)
hydrolase activity, acting on ester bondsGO:00167881090.91%4.12%1.27E-13(2.05E-10)
hydrolase activityGO:00167871090.91%11.45%3.61E-9(5.83E-6)
catalytic activityGO:00038241090.91%29.21%3.6E-5(0.06)
molecular_functionGO:000367411100%99.44%0.94(n.s)
molecular function unknownGO:000555419.09%35.75%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribonuclease P complexGO:0030677981.82%0.15%1.03E-26(1.66E-23)
nucleolar ribonuclease P complexGO:0005655981.82%0.15%1.03E-26(1.66E-23)
ribonuclease MRP complexGO:0000172981.82%0.17%5.66E-26(9.15E-23)
nucleolusGO:00057301090.91%4.58%3.74E-13(6.05E-10)
ribonucleoprotein complexGO:00305291090.91%7.19%3.46E-11(5.59E-8)
intracellular non-membrane-bound organelleGO:00432321090.91%14.3%3.28E-8(5.3E-5)
non-membrane-bound organelleGO:00432281090.91%14.3%3.28E-8(5.3E-5)
protein complexGO:00432341090.91%21.07%1.49E-6(2.41E-3)
nucleusGO:00056341090.91%31.01%6.4E-5(0.1)
intracellular membrane-bound organelleGO:004323111100%55.65%1.58E-3(n.s)
membrane-bound organelleGO:004322711100%55.65%1.58E-3(n.s)
organelleGO:004322611100%60.56%4E-3(n.s)
intracellular organelleGO:004322911100%60.56%4E-3(n.s)
intracellularGO:000562211100%77.03%0.06(n.s)
cellGO:000562311100%83.5%0.14(n.s)
mitochondrionGO:000573919.09%15.78%0.85(n.s)
cellular_componentGO:000557511100%99.61%0.96(n.s)
cytoplasmGO:0005737218.18%55.64%1(n.s)

 

 

cluster_95 (n = 13)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
generation of precursor metabolites and energyGO:00060911076.92%3.5%5.93E-13(9.58E-10)
coenzyme catabolismGO:0009109538.46%0.26%8.43E-11(1.36E-7)
cofactor catabolismGO:0051187538.46%0.28%1.17E-10(1.88E-7)
tricarboxylic acid cycle intermediate metabolismGO:0006100538.46%0.29%1.58E-10(2.55E-7)
energy derivation by oxidation of organic compoundsGO:0015980861.54%3.04%7.08E-10(1.14E-6)
coenzyme metabolismGO:0006732753.85%1.81%8.41E-10(1.36E-6)
cofactor metabolismGO:0051186753.85%2.26%4.01E-9(6.49E-6)
tricarboxylic acid cycleGO:0006099430.77%0.23%1.33E-8(2.15E-5)
acetyl-CoA catabolismGO:0046356430.77%0.23%1.33E-8(2.15E-5)
citrate metabolismGO:0006101323.08%0.06%2.55E-8(4.12E-5)
acetyl-CoA metabolismGO:0006084430.77%0.31%4.71E-8(7.6E-5)
main pathways of carbohydrate metabolismGO:0006092538.46%1.08%1.56E-7(2.52E-4)
aerobic respirationGO:0009060538.46%1.27%3.47E-7(5.61E-4)
cellular respirationGO:0045333538.46%1.35%4.68E-7(7.56E-4)
carbohydrate metabolismGO:0005975646.15%3.38%1.95E-6(3.15E-3)
NAD metabolismGO:0019674323.08%0.22%2.29E-6(3.71E-3)
NADH oxidationGO:0006116215.38%0.05%1.12E-5(0.02)
nicotinamide metabolismGO:0006769323.08%0.46%2.51E-5(0.04)
cellular carbohydrate metabolismGO:0044262538.46%3.08%2.78E-5(0.04)
pyridine nucleotide metabolismGO:0019362323.08%0.51%3.36E-5(0.05)
ethanol fermentationGO:0019655215.38%0.08%3.73E-5(0.06)
glycolytic fermentationGO:0019660215.38%0.09%5.59E-5(0.09)
NADH metabolismGO:0006734215.38%0.09%5.59E-5(0.09)
oxidoreduction coenzyme metabolismGO:0006733323.08%0.67%7.52E-5(0.12)
ethanol metabolismGO:0006067215.38%0.15%1.67E-4(0.27)
organic acid metabolismGO:0006082538.46%4.6%1.89E-4(0.31)
carboxylic acid metabolismGO:0019752538.46%4.6%1.89E-4(0.31)
glutamate biosynthesisGO:0006537215.38%0.2%2.88E-4(0.47)
vitamin metabolismGO:0006766323.08%1.13%3.66E-4(0.59)
water-soluble vitamin metabolismGO:0006767323.08%1.13%3.66E-4(0.59)
glutamate metabolismGO:0006536215.38%0.25%4.42E-4(0.71)
fermentationGO:0006113215.38%0.25%4.42E-4(0.71)
cellular catabolismGO:0044248538.46%5.84%5.76E-4(0.93)
nucleotide metabolismGO:0009117323.08%1.38%6.55E-4(n.s)
catabolismGO:0009056538.46%6.16%7.39E-4(n.s)
glutamine family amino acid biosynthesisGO:0009084215.38%0.37%1.01E-3(n.s)
electron transportGO:0006118215.38%0.48%1.68E-3(n.s)
NAD catabolismGO:001967717.69%0.02%**
vitamin catabolismGO:000911117.69%0.02%**
water-soluble vitamin catabolismGO:004236517.69%0.02%**
pyridine nucleotide catabolismGO:001936417.69%0.02%**
fumarate metabolismGO:000610617.69%0.02%**
mitochondrial electron transport, NADH to ubiquinoneGO:000612017.69%0.02%**
glutamine family amino acid metabolismGO:0009064215.38%0.67%3.23E-3(n.s)
nucleotide catabolismGO:000916617.69%0.03%4.02E-3(n.s)
malate metabolismGO:000610817.69%0.05%6.03E-3(n.s)
glyoxylate metabolismGO:004648717.69%0.06%8.03E-3(n.s)
glyoxylate cycleGO:000609717.69%0.06%8.03E-3(n.s)
propionate metabolismGO:001954117.69%0.08%0.01(n.s)
amino acid biosynthesisGO:0008652215.38%1.53%0.02(n.s)
cellular metabolismGO:00442371184.62%52.12%0.02(n.s)
metabolismGO:00081521184.62%52.93%0.02(n.s)
amine biosynthesisGO:0009309215.38%1.67%0.02(n.s)
nitrogen compound biosynthesisGO:0044271215.38%1.67%0.02(n.s)
aldehyde metabolismGO:000608117.69%0.29%0.04(n.s)
alcohol metabolismGO:0006066215.38%2.43%0.04(n.s)
ATP synthesis coupled electron transport (sensu Eukaryota)GO:004277517.69%0.39%0.05(n.s)
ATP synthesis coupled electron transportGO:004277317.69%0.39%0.05(n.s)
amino acid metabolismGO:0006520215.38%2.82%0.05(n.s)
amino acid and derivative metabolismGO:0006519215.38%3.05%0.06(n.s)
amine metabolismGO:0009308215.38%3.38%0.07(n.s)
nitrogen compound metabolismGO:0006807215.38%3.66%0.08(n.s)
oxidative phosphorylationGO:000611917.69%0.71%0.09(n.s)
macromolecule metabolismGO:0043170646.15%26.04%0.09(n.s)
primary metabolismGO:0044238969.23%48.71%0.11(n.s)
cellular macromolecule metabolismGO:0044260538.46%24.52%0.19(n.s)
cellular physiological processGO:00508751184.62%71.65%0.24(n.s)
phosphorylationGO:001631017.69%2.21%0.25(n.s)
cellular processGO:00099871184.62%72.29%0.26(n.s)
physiological processGO:00075821184.62%73.68%0.29(n.s)
phosphate metabolismGO:000679617.69%2.91%0.32(n.s)
phosphorus metabolismGO:000679317.69%2.91%0.32(n.s)
transportGO:0006810215.38%14.27%0.57(n.s)
establishment of localizationGO:0051234215.38%14.39%0.58(n.s)
localizationGO:0051179215.38%14.82%0.6(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139323.08%23.17%0.61(n.s)
cellular biosynthesisGO:0044249215.38%17.05%0.68(n.s)
biosynthesisGO:0009058215.38%18.28%0.72(n.s)
biological process unknownGO:0000004215.38%25.64%0.88(n.s)
biological_processGO:000815013100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
citrate (Si)-synthase activityGO:0004108323.08%0.05%6.38E-9(1.03E-5)
oxidoreductase activityGO:0016491753.85%3.73%1.31E-7(2.12E-4)
oxidoreductase activity, acting on NADH or NADPHGO:0016651323.08%0.14%5.32E-7(8.6E-4)
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transferGO:0046912323.08%0.15%7.59E-7(1.23E-3)
NADH dehydrogenase activityGO:0003954215.38%0.03%3.74E-6(6.05E-3)
electron transporter activityGO:0005489323.08%0.34%9.61E-6(0.02)
oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptorGO:0016898215.38%0.06%2.24E-5(0.04)
lactate dehydrogenase activityGO:0004457215.38%0.06%2.24E-5(0.04)
catalytic activityGO:00038241184.62%29.21%5.44E-5(0.09)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614323.08%1.18%4.12E-4(0.67)
transferase activity, transferring acyl groupsGO:0016746323.08%1.43%7.22E-4(n.s)
fumarate hydratase activityGO:000433317.69%0.02%**
L-lactate dehydrogenase (cytochrome) activityGO:000446017.69%0.02%**
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptorGO:001665517.69%0.02%**
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptorGO:001664917.69%0.02%**
D-lactate dehydrogenase (cytochrome) activityGO:000445817.69%0.05%6.03E-3(n.s)
L-malate dehydrogenase activityGO:003006017.69%0.05%6.03E-3(n.s)
malate dehydrogenase activityGO:001661517.69%0.06%8.03E-3(n.s)
electron carrier activityGO:000905517.69%0.08%0.01(n.s)
oxidoreductase activity, acting on the CH-NH group of donorsGO:001664517.69%0.22%0.03(n.s)
transporter activityGO:0005215323.08%6.64%0.05(n.s)
hydro-lyase activityGO:001683617.69%0.43%0.05(n.s)
carbon-oxygen lyase activityGO:001683517.69%0.56%0.07(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:001661617.69%1.07%0.13(n.s)
transferase activityGO:0016740323.08%10.13%0.14(n.s)
lyase activityGO:001682917.69%1.27%0.15(n.s)
carrier activityGO:000538617.69%1.64%0.19(n.s)
molecular_functionGO:000367413100%99.44%0.93(n.s)
molecular function unknownGO:000555417.69%35.75%1(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:000573913100%15.78%3.54E-11(5.72E-8)
mitochondrial matrixGO:0005759430.77%2.52%2.34E-4(0.38)
cytoplasmGO:000573713100%55.64%4.85E-4(0.78)
intracellular membrane-bound organelleGO:004323113100%55.65%4.87E-4(0.79)
membrane-bound organelleGO:004322713100%55.65%4.87E-4(0.79)
organelleGO:004322613100%60.56%1.46E-3(n.s)
intracellular organelleGO:004322913100%60.56%1.46E-3(n.s)
intracellularGO:000562213100%77.03%0.03(n.s)
mitochondrial inner membraneGO:0005743215.38%2.43%0.04(n.s)
inner membraneGO:0019866215.38%2.43%0.04(n.s)
mitochondrial intermembrane spaceGO:000575817.69%0.39%0.05(n.s)
mitochondrial membraneGO:0005740215.38%3.16%0.06(n.s)
cellGO:000562313100%83.5%0.1(n.s)
peroxisomeGO:000577717.69%0.87%0.11(n.s)
microbodyGO:004257917.69%0.87%0.11(n.s)
organelle membraneGO:0031090215.38%8.58%0.31(n.s)
membraneGO:0016020215.38%15.38%0.62(n.s)
cytosolGO:000582917.69%10.08%0.75(n.s)
cellular_componentGO:000557513100%99.61%0.95(n.s)

 

 

cluster_10 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein-mitochondrial targetingGO:0006626360%0.73%3.58E-6(5.79E-3)
mitochondrial intermembrane space protein importGO:0045041240%0.09%7.19E-6(0.01)
signal peptide processingGO:0006465240%0.11%1.01E-5(0.02)
peptide metabolismGO:0006518240%0.12%1.34E-5(0.02)
protein processingGO:0016485240%0.51%2.51E-4(0.41)
protein targetingGO:0006605360%3.42%3.76E-4(0.61)
intracellular protein transportGO:0006886360%3.7%4.74E-4(0.77)
protein transportGO:0015031360%3.79%5.1E-4(0.82)
establishment of protein localizationGO:0045184360%3.95%5.74E-4(0.93)
protein localizationGO:0008104360%4.37%7.72E-4(n.s)
protein importGO:0017038240%1.39%1.87E-3(n.s)
intracellular transportGO:0046907360%7.53%3.78E-3(n.s)
protein complex assemblyGO:0006461240%2.26%4.86E-3(n.s)
proteolysis and peptidolysisGO:0006508240%2.42%5.53E-3(n.s)
cellular protein catabolismGO:0044257240%2.42%5.53E-3(n.s)
protein catabolismGO:0030163240%2.74%7.08E-3(n.s)
biopolymer catabolismGO:0043285240%2.93%8.04E-3(n.s)
inner mitochondrial membrane organization and biogenesisGO:0007007120%0.2%0.01(n.s)
mitochondrial membrane organization and biogenesisGO:0007006120%0.29%0.01(n.s)
cellular macromolecule catabolismGO:0044265240%4.51%0.02(n.s)
ergosterol biosynthesisGO:0006696120%0.39%0.02(n.s)
ergosterol metabolismGO:0008204120%0.39%0.02(n.s)
macromolecule catabolismGO:0009057240%4.83%0.02(n.s)
sterol biosynthesisGO:0016126120%0.45%0.02(n.s)
transportGO:0006810360%14.27%0.02(n.s)
establishment of localizationGO:0051234360%14.39%0.02(n.s)
membrane organization and biogenesisGO:0016044120%0.48%0.02(n.s)
localizationGO:0051179360%14.82%0.03(n.s)
steroid biosynthesisGO:0006694120%0.56%0.03(n.s)
sterol metabolismGO:0016125120%0.57%0.03(n.s)
cellular catabolismGO:0044248240%5.84%0.03(n.s)
catabolismGO:0009056240%6.16%0.03(n.s)
steroid metabolismGO:0008202120%0.7%0.03(n.s)
protein modificationGO:0006464240%6.68%0.04(n.s)
aerobic respirationGO:0009060120%1.27%0.06(n.s)
cellular respirationGO:0045333120%1.35%0.07(n.s)
biopolymer modificationGO:0043412240%9.25%0.07(n.s)
mitochondrion organization and biogenesisGO:0007005120%1.47%0.07(n.s)
lipid biosynthesisGO:0008610120%1.92%0.09(n.s)
alcohol metabolismGO:0006066120%2.43%0.12(n.s)
energy derivation by oxidation of organic compoundsGO:0015980120%3.04%0.14(n.s)
cellular lipid metabolismGO:0044255120%3.16%0.15(n.s)
lipid metabolismGO:0006629120%3.38%0.16(n.s)
generation of precursor metabolites and energyGO:0006091120%3.5%0.16(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
cellular metabolismGO:0044237480%52.12%0.22(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
metabolismGO:0008152480%52.93%0.23(n.s)
cellular protein metabolismGO:0044267240%21.7%0.3(n.s)
protein metabolismGO:0019538240%22.06%0.31(n.s)
cellular macromolecule metabolismGO:0044260240%24.52%0.36(n.s)
biopolymer metabolismGO:0043283240%25.06%0.37(n.s)
macromolecule metabolismGO:0043170240%26.04%0.39(n.s)
primary metabolismGO:0044238360%48.71%0.48(n.s)
organelle organization and biogenesisGO:0006996120%15.69%0.57(n.s)
cell organization and biogenesisGO:0016043120%17.98%0.63(n.s)
biosynthesisGO:0009058120%18.28%0.64(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ATPase activityGO:0016887360%2.52%1.52E-4(0.25)
metallopeptidase activityGO:0008237240%0.43%1.8E-4(0.29)
nucleoside-triphosphatase activityGO:0017111360%3.42%3.76E-4(0.61)
pyrophosphatase activityGO:0016462360%3.67%4.62E-4(0.75)
hydrolase activity, acting on acid anhydridesGO:0016817360%3.69%4.68E-4(0.76)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818360%3.69%4.68E-4(0.76)
hydroxymethylglutaryl-CoA reductase (NADPH) activityGO:0004420120%0.03%1.55E-3(n.s)
peptidase activityGO:0008233240%2.48%5.81E-3(n.s)
hydrolase activityGO:0016787360%11.45%0.01(n.s)
catalytic activityGO:0003824480%29.21%0.03(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616120%1.07%0.05(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614120%1.18%0.06(n.s)
oxidoreductase activityGO:0016491120%3.73%0.17(n.s)
molecular function unknownGO:0005554120%35.75%0.89(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
m-AAA complexGO:0005745240%0.03%4.8E-7(7.76E-4)
organelle membraneGO:00310905100%8.58%4.58E-6(7.4E-3)
mitochondrial membraneGO:0005740480%3.16%4.72E-6(7.63E-3)
membraneGO:00160205100%15.38%8.54E-5(0.14)
mitochondrionGO:00057395100%15.78%9.72E-5(0.16)
mitochondrial inner membraneGO:0005743360%2.43%1.36E-4(0.22)
inner membraneGO:0019866360%2.43%1.36E-4(0.22)
mitochondrial outer membraneGO:0005741120%0.53%0.03(n.s)
outer membraneGO:0019867120%0.53%0.03(n.s)
cytoplasmGO:00057375100%55.64%0.05(n.s)
intracellular membrane-bound organelleGO:00432315100%55.65%0.05(n.s)
membrane-bound organelleGO:00432275100%55.65%0.05(n.s)
nuclear membraneGO:0005635120%1.53%0.07(n.s)
organelleGO:00432265100%60.56%0.08(n.s)
intracellular organelleGO:00432295100%60.56%0.08(n.s)
endoplasmic reticulum membraneGO:0005789120%1.78%0.09(n.s)
nuclear envelope-endoplasmic reticulum networkGO:0042175120%1.95%0.09(n.s)
mitochondrial matrixGO:0005759120%2.52%0.12(n.s)
endomembrane systemGO:0012505120%3.7%0.17(n.s)
endoplasmic reticulumGO:0005783120%5.84%0.26(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
protein complexGO:0043234240%21.07%0.28(n.s)
cellGO:00056235100%83.5%0.41(n.s)
nucleusGO:0005634120%31.01%0.84(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_12 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
fatty acid biosynthesisGO:0006633480%0.19%3.42E-11(5.53E-8)
carboxylic acid biosynthesisGO:0046394480%0.26%1.64E-10(2.65E-7)
organic acid biosynthesisGO:0016053480%0.26%1.64E-10(2.65E-7)
fatty acid metabolismGO:0006631480%0.67%8.49E-9(1.37E-5)
lipid biosynthesisGO:0008610480%1.92%6.39E-7(1.03E-3)
cellular lipid metabolismGO:0044255480%3.16%4.72E-6(7.63E-3)
lipid metabolismGO:0006629480%3.38%6.16E-6(9.96E-3)
organic acid metabolismGO:0006082480%4.6%2.12E-5(0.03)
carboxylic acid metabolismGO:0019752480%4.6%2.12E-5(0.03)
protein-cofactor linkageGO:0018065120%0.06%3.1E-3(n.s)
cellular biosynthesisGO:0044249480%17.05%3.64E-3(n.s)
biosynthesisGO:0009058480%18.28%4.75E-3(n.s)
primary metabolismGO:00442385100%48.71%0.03(n.s)
cellular metabolismGO:00442375100%52.12%0.04(n.s)
metabolismGO:00081525100%52.93%0.04(n.s)
protein foldingGO:0006457120%1.04%0.05(n.s)
cellular physiological processGO:00508755100%71.65%0.19(n.s)
cellular processGO:00099875100%72.29%0.2(n.s)
physiological processGO:00075825100%73.68%0.22(n.s)
response to stressGO:0006950120%6.09%0.27(n.s)
protein modificationGO:0006464120%6.68%0.29(n.s)
cellular protein metabolismGO:0044267240%21.7%0.3(n.s)
protein metabolismGO:0019538240%22.06%0.31(n.s)
response to stimulusGO:0050896120%8.41%0.36(n.s)
cellular macromolecule metabolismGO:0044260240%24.52%0.36(n.s)
biopolymer modificationGO:0043412120%9.25%0.38(n.s)
macromolecule metabolismGO:0043170240%26.04%0.39(n.s)
biopolymer metabolismGO:0043283120%25.06%0.76(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
fatty-acid synthase activityGO:0004312360%0.12%1.25E-8(2.02E-5)
acyltransferase activityGO:0008415360%1.19%1.6E-5(0.03)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747360%1.19%1.6E-5(0.03)
transferase activity, transferring acyl groupsGO:0016746360%1.43%2.74E-5(0.04)
3-oxoacyl-[acyl-carrier protein] synthase activityGO:0004315120%0.02%**
3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activityGO:0004317120%0.02%**
[acyl-carrier protein] S-acetyltransferase activityGO:0004313120%0.02%**
enoyl-[acyl-carrier protein] reductase (NADH) activityGO:0004318120%0.02%**
CoA carboxylase activityGO:0016421120%0.03%1.55E-3(n.s)
3-oxoacyl-[acyl-carrier protein] reductase activityGO:0004316120%0.03%1.55E-3(n.s)
enoyl-[acyl-carrier protein] reductase activityGO:0016631120%0.03%1.55E-3(n.s)
3-hydroxyacyl-[acyl-carrier protein] dehydratase activityGO:0019171120%0.03%1.55E-3(n.s)
acetyl-CoA carboxylase activityGO:0003989120%0.03%1.55E-3(n.s)
S-acetyltransferase activityGO:0016418120%0.03%1.55E-3(n.s)
malonyltransferase activityGO:0016420120%0.03%1.55E-3(n.s)
[acyl-carrier protein] S-malonyltransferase activityGO:0004314120%0.03%1.55E-3(n.s)
chaperone activator activityGO:0030189120%0.03%1.55E-3(n.s)
S-malonyltransferase activityGO:0016419120%0.03%1.55E-3(n.s)
phosphopantetheinyltransferase activityGO:0008897120%0.05%2.32E-3(n.s)
ligase activity, forming carbon-carbon bondsGO:0016885120%0.06%3.1E-3(n.s)
S-acyltransferase activityGO:0016417120%0.11%5.41E-3(n.s)
chaperone regulator activityGO:0030188120%0.12%6.18E-3(n.s)
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptorGO:0016628120%0.14%6.95E-3(n.s)
phosphotransferase activity, for other substituted phosphate groupsGO:0016780120%0.15%7.72E-3(n.s)
transferase activityGO:0016740360%10.13%8.85E-3(n.s)
oxidoreductase activityGO:0016491240%3.73%0.01(n.s)
oxidoreductase activity, acting on the CH-CH group of donorsGO:0016627120%0.29%0.01(n.s)
hydro-lyase activityGO:0016836120%0.43%0.02(n.s)
carbon-oxygen lyase activityGO:0016835120%0.56%0.03(n.s)
catalytic activityGO:0003824480%29.21%0.03(n.s)
acetyltransferase activityGO:0016407120%0.71%0.04(n.s)
enzyme activator activityGO:0008047120%0.91%0.04(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616120%1.07%0.05(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614120%1.18%0.06(n.s)
lyase activityGO:0016829120%1.27%0.06(n.s)
ligase activityGO:0016874120%1.89%0.09(n.s)
enzyme regulator activityGO:0030234120%2.54%0.12(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772120%5.19%0.23(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
fatty acid synthase complexGO:0005835240%0.03%4.8E-7(7.76E-4)
mitochondrionGO:0005739480%15.78%2.7E-3(n.s)
cytoplasmGO:00057375100%55.64%0.05(n.s)
intracellular membrane-bound organelleGO:0043231480%55.65%0.27(n.s)
membrane-bound organelleGO:0043227480%55.65%0.27(n.s)
intracellularGO:00056225100%77.03%0.27(n.s)
protein complexGO:0043234240%21.07%0.28(n.s)
organelleGO:0043226480%60.56%0.35(n.s)
intracellular organelleGO:0043229480%60.56%0.35(n.s)
cellGO:00056235100%83.5%0.41(n.s)
cytosolGO:0005829120%10.08%0.41(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_15 (n = 10)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein-mitochondrial targetingGO:0006626660%0.73%2.2E-11(3.55E-8)
mitochondrial matrix protein importGO:0030150550%0.31%4.15E-11(6.7E-8)
protein foldingGO:0006457660%1.04%2.02E-10(3.27E-7)
protein importGO:0017038550%1.39%1.12E-7(1.81E-4)
protein targetingGO:0006605660%3.42%2.82E-7(4.55E-4)
intracellular protein transportGO:0006886660%3.7%4.49E-7(7.25E-4)
protein transportGO:0015031660%3.79%5.2E-7(8.4E-4)
establishment of protein localizationGO:0045184660%3.95%6.58E-7(1.06E-3)
protein localizationGO:0008104660%4.37%1.19E-6(1.93E-3)
intracellular transportGO:0046907660%7.53%2.85E-5(0.05)
transportGO:0006810660%14.27%1.04E-3(n.s)
establishment of localizationGO:0051234660%14.39%1.09E-3(n.s)
localizationGO:0051179660%14.82%1.28E-3(n.s)
cellular protein metabolismGO:0044267770%21.7%1.44E-3(n.s)
protein refoldingGO:0042026110%0.02%**
protein metabolismGO:0019538770%22.06%1.59E-3(n.s)
cellular macromolecule metabolismGO:0044260770%24.52%3.09E-3(n.s)
posttranslational protein foldingGO:0051084110%0.03%3.1E-3(n.s)
macromolecule metabolismGO:0043170770%26.04%4.47E-3(n.s)
cellular protein catabolismGO:0044257220%2.42%0.02(n.s)
proteolysis and peptidolysisGO:0006508220%2.42%0.02(n.s)
response to heatGO:0009408110%0.26%0.03(n.s)
protein catabolismGO:0030163220%2.74%0.03(n.s)
response to temperatureGO:0009266110%0.31%0.03(n.s)
biopolymer catabolismGO:0043285220%2.93%0.03(n.s)
mitochondrial genome maintenanceGO:0000002110%0.42%0.04(n.s)
cellular macromolecule catabolismGO:0044265220%4.51%0.07(n.s)
macromolecule catabolismGO:0009057220%4.83%0.08(n.s)
cellular catabolismGO:0044248220%5.84%0.11(n.s)
response to stressGO:0006950220%6.09%0.12(n.s)
catabolismGO:0009056220%6.16%0.12(n.s)
mitochondrion organization and biogenesisGO:0007005110%1.47%0.14(n.s)
primary metabolismGO:0044238770%48.71%0.15(n.s)
cellular physiological processGO:0050875990%71.65%0.18(n.s)
cellular processGO:0009987990%72.29%0.19(n.s)
response to stimulusGO:0050896220%8.41%0.2(n.s)
cellular metabolismGO:0044237770%52.12%0.21(n.s)
physiological processGO:0007582990%73.68%0.22(n.s)
metabolismGO:0008152770%52.93%0.22(n.s)
response to abiotic stimulusGO:0009628110%3.52%0.3(n.s)
response to external stimulusGO:0009605110%3.87%0.33(n.s)
biopolymer metabolismGO:0043283220%25.06%0.76(n.s)
organelle organization and biogenesisGO:0006996110%15.69%0.82(n.s)
cell organization and biogenesisGO:0016043110%17.98%0.86(n.s)
biological process unknownGO:0000004110%25.64%0.95(n.s)
biological_processGO:000815010100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
unfolded protein bindingGO:0051082550%0.9%1.2E-8(1.93E-5)
protein bindingGO:0005515550%7.39%3.98E-4(0.64)
bindingGO:0005488660%17.35%2.99E-3(n.s)
ATP-dependent peptidase activityGO:0004176110%0.03%3.1E-3(n.s)
chaperone bindingGO:0051087110%0.17%0.02(n.s)
single-stranded DNA bindingGO:0003697110%0.19%0.02(n.s)
ATP bindingGO:0005524110%0.22%0.02(n.s)
ATPase activityGO:0016887220%2.52%0.02(n.s)
adenyl nucleotide bindingGO:0030554110%0.26%0.03(n.s)
nucleoside-triphosphatase activityGO:0017111220%3.42%0.04(n.s)
purine nucleotide bindingGO:0017076110%0.5%0.05(n.s)
pyrophosphatase activityGO:0016462220%3.67%0.05(n.s)
nucleotide bindingGO:0000166110%0.51%0.05(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817220%3.69%0.05(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818220%3.69%0.05(n.s)
protein transporter activityGO:0008565110%0.77%0.07(n.s)
hydrolase activityGO:0016787330%11.45%0.1(n.s)
peptidase activityGO:0008233110%2.48%0.22(n.s)
enzyme regulator activityGO:0030234110%2.54%0.23(n.s)
DNA bindingGO:0003677110%3.18%0.28(n.s)
transporter activityGO:0005215110%6.64%0.5(n.s)
catalytic activityGO:0003824330%29.21%0.6(n.s)
nucleic acid bindingGO:0003676110%9.87%0.65(n.s)
molecular function unknownGO:0005554220%35.75%0.92(n.s)
molecular_functionGO:000367410100%99.44%0.95(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial matrixGO:0005759880%2.52%6E-12(9.7E-9)
mitochondrionGO:000573910100%15.78%9.24E-9(1.49E-5)
nucleoidGO:0009295330%0.36%4.66E-6(7.54E-3)
mitochondrial nucleoidGO:0042645330%0.36%4.66E-6(7.54E-3)
presequence translocase-associated import motorGO:0001405220%0.08%2.15E-5(0.03)
mitochondrial inner membrane presequence translocase complexGO:0005744220%0.14%7.73E-5(0.12)
mitochondrial inner membraneGO:0005743330%2.43%1.49E-3(n.s)
inner membraneGO:0019866330%2.43%1.49E-3(n.s)
cytoplasmGO:000573710100%55.64%2.83E-3(n.s)
intracellular membrane-bound organelleGO:004323110100%55.65%2.83E-3(n.s)
membrane-bound organelleGO:004322710100%55.65%2.83E-3(n.s)
mitochondrial membraneGO:0005740330%3.16%3.17E-3(n.s)
organelleGO:004322610100%60.56%6.61E-3(n.s)
intracellular organelleGO:004322910100%60.56%6.61E-3(n.s)
organelle membraneGO:0031090330%8.58%0.05(n.s)
intracellularGO:000562210100%77.03%0.07(n.s)
cellGO:000562310100%83.5%0.16(n.s)
membraneGO:0016020330%15.38%0.19(n.s)
protein complexGO:0043234220%21.07%0.66(n.s)
cellular_componentGO:000557510100%99.61%0.96(n.s)

 

 

cluster_17 (n = 5)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
aerobic respirationGO:0009060120%1.27%0.06(n.s)
cellular respirationGO:0045333120%1.35%0.07(n.s)
biological process unknownGO:0000004360%25.64%0.11(n.s)
energy derivation by oxidation of organic compoundsGO:0015980120%3.04%0.14(n.s)
generation of precursor metabolites and energyGO:0006091120%3.5%0.16(n.s)
transportGO:0006810120%14.27%0.54(n.s)
establishment of localizationGO:0051234120%14.39%0.54(n.s)
localizationGO:0051179120%14.82%0.55(n.s)
cellular metabolismGO:0044237120%52.12%0.97(n.s)
cellular physiological processGO:0050875240%71.65%0.98(n.s)
metabolismGO:0008152120%52.93%0.98(n.s)
cellular processGO:0009987240%72.29%0.98(n.s)
physiological processGO:0007582240%73.68%0.98(n.s)
biological_processGO:00081505100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
inorganic diphosphatase activityGO:0004427120%0.03%1.55E-3(n.s)
pyrophosphatase activityGO:0016462120%3.67%0.17(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818120%3.69%0.17(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817120%3.69%0.17(n.s)
molecular function unknownGO:0005554360%35.75%0.25(n.s)
transporter activityGO:0005215120%6.64%0.29(n.s)
hydrolase activityGO:0016787120%11.45%0.46(n.s)
catalytic activityGO:0003824120%29.21%0.82(n.s)
molecular_functionGO:00036745100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739480%15.78%2.7E-3(n.s)
mitochondrial inner membraneGO:0005743120%2.43%0.12(n.s)
inner membraneGO:0019866120%2.43%0.12(n.s)
mitochondrial membraneGO:0005740120%3.16%0.15(n.s)
cytoplasmGO:0005737480%55.64%0.27(n.s)
intracellular membrane-bound organelleGO:0043231480%55.65%0.27(n.s)
membrane-bound organelleGO:0043227480%55.65%0.27(n.s)
organelleGO:0043226480%60.56%0.35(n.s)
intracellular organelleGO:0043229480%60.56%0.35(n.s)
organelle membraneGO:0031090120%8.58%0.36(n.s)
membraneGO:0016020120%15.38%0.57(n.s)
cellular component unknownGO:0008372120%15.74%0.58(n.s)
intracellularGO:0005622480%77.03%0.68(n.s)
cellGO:0005623480%83.5%0.81(n.s)
cellular_componentGO:00055755100%99.61%0.98(n.s)

 

 

cluster_16 (n = 16)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein-mitochondrial targetingGO:00066261593.75%0.73%1.13E-32(1.82E-29)
protein importGO:00170381487.5%1.39%4.29E-25(6.94E-22)
protein targetingGO:00066051593.75%3.42%1.01E-21(1.63E-18)
intracellular protein transportGO:00068861593.75%3.7%3.38E-21(5.46E-18)
protein transportGO:00150311593.75%3.79%4.95E-21(8E-18)
establishment of protein localizationGO:00451841593.75%3.95%9.16E-21(1.48E-17)
protein localizationGO:00081041593.75%4.37%4.3E-20(6.95E-17)
mitochondrial inner membrane protein importGO:0045039743.75%0.14%4.44E-18(7.18E-15)
intracellular transportGO:00469071593.75%7.53%1.72E-16(2.78E-13)
inner mitochondrial membrane organization and biogenesisGO:0007007743.75%0.2%2.11E-16(3.41E-13)
mitochondrial membrane organization and biogenesisGO:0007006743.75%0.29%6.14E-15(9.93E-12)
mitochondrial matrix protein importGO:0030150743.75%0.31%9.44E-15(1.53E-11)
membrane organization and biogenesisGO:0016044743.75%0.48%3.16E-13(5.11E-10)
transportGO:00068101593.75%14.27%2.6E-12(4.2E-9)
establishment of localizationGO:00512341593.75%14.39%2.96E-12(4.78E-9)
localizationGO:00511791593.75%14.82%4.61E-12(7.45E-9)
mitochondrion organization and biogenesisGO:0007005743.75%1.47%1.23E-9(1.98E-6)
cellular physiological processGO:005087516100%71.65%4.79E-3(n.s)
cellular processGO:000998716100%72.29%5.52E-3(n.s)
organelle organization and biogenesisGO:0006996743.75%15.69%7.13E-3(n.s)
physiological processGO:000758216100%73.68%7.5E-3(n.s)
cell organization and biogenesisGO:0016043743.75%17.98%0.02(n.s)
mRNA polyadenylylationGO:000637816.25%0.28%0.04(n.s)
mRNA 3'-end processingGO:003112416.25%0.31%0.05(n.s)
RNA 3'-end processingGO:003112316.25%0.33%0.05(n.s)
protein-membrane targetingGO:000661216.25%0.48%0.07(n.s)
mRNA processingGO:000639716.25%2.03%0.28(n.s)
mRNA metabolismGO:001607116.25%2.85%0.37(n.s)
RNA processingGO:000639616.25%5.33%0.58(n.s)
RNA metabolismGO:001607016.25%8.32%0.75(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613916.25%23.17%0.99(n.s)
biopolymer metabolismGO:004328316.25%25.06%0.99(n.s)
biological_processGO:000815016100%99.98%1(n.s)
primary metabolismGO:004423816.25%48.71%1(n.s)
cellular metabolismGO:004423716.25%52.12%1(n.s)
metabolismGO:000815216.25%52.93%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein transporter activityGO:00085651381.25%0.77%3.64E-26(5.88E-23)
transporter activityGO:00052151381.25%6.64%1.93E-13(3.12E-10)
unfolded protein bindingGO:0051082318.75%0.9%3.55E-4(0.57)
ATPase stimulator activityGO:000167116.25%0.05%7.42E-3(n.s)
protein bindingGO:0005515425%7.39%0.03(n.s)
enzyme activator activityGO:000804716.25%0.91%0.14(n.s)
bindingGO:0005488425%17.35%0.3(n.s)
enzyme regulator activityGO:003023416.25%2.54%0.34(n.s)
molecular_functionGO:000367416100%99.44%0.91(n.s)
molecular function unknownGO:0005554318.75%35.75%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membrane presequence translocase complexGO:0005744743.75%0.14%4.44E-18(7.18E-15)
mitochondrial inner membraneGO:00057431168.75%2.43%4.88E-15(7.88E-12)
inner membraneGO:00198661168.75%2.43%4.88E-15(7.88E-12)
mitochondrial membraneGO:00057401168.75%3.16%9.14E-14(1.48E-10)
mitochondrionGO:000573916100%15.78%1.34E-13(2.17E-10)
protein complexGO:004323416100%21.07%1.4E-11(2.27E-8)
mitochondrial intermembrane space protein transporter complexGO:0042719425%0.06%2.52E-11(4.07E-8)
mitochondrial inner membrane protein insertion complexGO:0042721425%0.06%2.52E-11(4.07E-8)
mitochondrial intermembrane spaceGO:0005758531.25%0.39%2.42E-9(3.91E-6)
organelle membraneGO:00310901168.75%8.58%4.96E-9(8.01E-6)
presequence translocase-associated import motorGO:0001405318.75%0.08%1.25E-7(2.01E-4)
membraneGO:00160201168.75%15.38%2.24E-6(3.62E-3)
cytoplasmGO:000573716100%55.64%8.31E-5(0.13)
intracellular membrane-bound organelleGO:004323116100%55.65%8.35E-5(0.13)
membrane-bound organelleGO:004322716100%55.65%8.35E-5(0.13)
organelleGO:004322616100%60.56%3.24E-4(0.52)
intracellular organelleGO:004322916100%60.56%3.24E-4(0.52)
intracellularGO:000562216100%77.03%0.02(n.s)
polysomeGO:000584416.25%0.19%0.03(n.s)
cellGO:000562316100%83.5%0.06(n.s)
mitochondrial matrixGO:000575916.25%2.52%0.34(n.s)
ribonucleoprotein complexGO:003052916.25%7.19%0.7(n.s)
cellular_componentGO:000557516100%99.61%0.94(n.s)
nucleusGO:000563416.25%31.01%1(n.s)

 

 

cluster_155 (n = 18)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ATP biosynthesisGO:000675418100%0.31%3.28E-51(5.3E-48)
nucleoside phosphate metabolismGO:000675318100%0.31%3.28E-51(5.3E-48)
energy coupled proton transport, down electrochemical gradientGO:001598518100%0.31%3.28E-51(5.3E-48)
ATP synthesis coupled proton transportGO:001598618100%0.31%3.28E-51(5.3E-48)
ATP metabolismGO:004603418100%0.31%3.28E-51(5.3E-48)
purine nucleoside triphosphate metabolismGO:000914418100%0.34%1.26E-49(2.04E-46)
purine ribonucleoside triphosphate metabolismGO:000920518100%0.34%1.26E-49(2.04E-46)
purine nucleoside triphosphate biosynthesisGO:000914518100%0.34%1.26E-49(2.04E-46)
purine ribonucleoside triphosphate biosynthesisGO:000920618100%0.34%1.26E-49(2.04E-46)
ribonucleoside triphosphate biosynthesisGO:000920118100%0.36%5.81E-49(9.39E-46)
ribonucleoside triphosphate metabolismGO:000919918100%0.36%5.81E-49(9.39E-46)
nucleoside triphosphate biosynthesisGO:000914218100%0.37%2.32E-48(3.76E-45)
hydrogen transportGO:000681818100%0.37%2.32E-48(3.76E-45)
proton transportGO:001599218100%0.37%2.32E-48(3.76E-45)
nucleoside triphosphate metabolismGO:000914118100%0.39%8.3E-48(1.34E-44)
monovalent inorganic cation transportGO:001567218100%0.45%5.98E-46(9.66E-43)
purine ribonucleotide biosynthesisGO:000915218100%0.57%3.05E-43(4.93E-40)
ribonucleotide biosynthesisGO:000926018100%0.59%5.8E-43(9.37E-40)
purine ribonucleotide metabolismGO:000915018100%0.6%1.08E-42(1.74E-39)
ribonucleotide metabolismGO:000925918100%0.62%1.96E-42(3.16E-39)
purine nucleotide biosynthesisGO:000616418100%0.65%6.11E-42(9.87E-39)
group transfer coenzyme metabolismGO:000675218100%0.68%1.78E-41(2.87E-38)
purine nucleotide metabolismGO:000616318100%0.7%2.96E-41(4.79E-38)
oxidative phosphorylationGO:000611918100%0.71%4.87E-41(7.87E-38)
nucleotide biosynthesisGO:000916518100%0.84%1.67E-39(2.71E-36)
coenzyme biosynthesisGO:000910818100%0.87%3.67E-39(5.93E-36)
cofactor biosynthesisGO:005118818100%1.08%4.01E-37(6.47E-34)
cation transportGO:000681218100%1.36%4.18E-35(6.75E-32)
nucleotide metabolismGO:000911718100%1.38%5.24E-35(8.46E-32)
ion transportGO:000681118100%1.64%1.67E-33(2.69E-30)
coenzyme metabolismGO:000673218100%1.81%1.15E-32(1.85E-29)
phosphorylationGO:001631018100%2.21%5.52E-31(8.92E-28)
cofactor metabolismGO:005118618100%2.26%8.22E-31(1.33E-27)
phosphate metabolismGO:000679618100%2.91%1E-28(1.62E-25)
phosphorus metabolismGO:000679318100%2.91%1E-28(1.62E-25)
generation of precursor metabolites and energyGO:000609118100%3.5%3.18E-27(5.15E-24)
transportGO:000681018100%14.27%5.19E-16(8.38E-13)
establishment of localizationGO:005123418100%14.39%6.07E-16(9.81E-13)
localizationGO:005117918100%14.82%1.04E-15(1.68E-12)
cellular biosynthesisGO:004424918100%17.05%1.33E-14(2.14E-11)
biosynthesisGO:000905818100%18.28%4.66E-14(7.53E-11)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:000613918100%23.17%3.43E-12(5.54E-9)
primary metabolismGO:004423818100%48.71%2.33E-6(3.76E-3)
cellular metabolismGO:004423718100%52.12%7.89E-6(0.01)
metabolismGO:000815218100%52.93%1.04E-5(0.02)
cellular physiological processGO:005087518100%71.65%2.46E-3(n.s)
age-dependent general metabolic decline during replicative cell agingGO:000132115.56%0.02%**
cellular processGO:000998718100%72.29%2.88E-3(n.s)
physiological processGO:000758218100%73.68%4.06E-3(n.s)
protein complex assemblyGO:0006461316.67%2.26%7.21E-3(n.s)
age-dependent general metabolic declineGO:000757115.56%0.12%0.02(n.s)
replicative cell agingGO:000130215.56%0.51%0.09(n.s)
cell agingGO:000756915.56%0.64%0.11(n.s)
agingGO:000756815.56%0.65%0.11(n.s)
cell deathGO:000821915.56%0.71%0.12(n.s)
deathGO:001626515.56%0.73%0.12(n.s)
developmentGO:000727515.56%5.73%0.65(n.s)
cellular protein metabolismGO:0044267316.67%21.7%0.78(n.s)
protein metabolismGO:0019538316.67%22.06%0.79(n.s)
cellular macromolecule metabolismGO:0044260316.67%24.52%0.85(n.s)
macromolecule metabolismGO:0043170316.67%26.04%0.88(n.s)
biological_processGO:000815018100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrogen-transporting ATP synthase activity, rotational mechanismGO:00469331583.33%0.23%7.69E-43(1.24E-39)
hydrogen ion transporter activityGO:00150781583.33%0.84%6.54E-30(1.06E-26)
monovalent inorganic cation transporter activityGO:00150771583.33%0.88%1.66E-29(2.69E-26)
cation transporter activityGO:00083241583.33%1.89%4.52E-24(7.3E-21)
ion transporter activityGO:00150751583.33%2.21%5.55E-23(8.98E-20)
transporter activityGO:00052151583.33%6.64%1.17E-15(1.89E-12)
structural molecule activityGO:0005198738.89%5.51%2.74E-5(0.04)
enzyme inhibitor activityGO:000485715.56%0.34%0.06(n.s)
enzyme regulator activityGO:003023415.56%2.54%0.37(n.s)
molecular_functionGO:000367418100%99.44%0.9(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrogen-translocating F-type ATPase complexGO:004525518100%0.31%3.28E-51(5.3E-48)
proton-transporting ATP synthase complexGO:004525918100%0.31%3.28E-51(5.3E-48)
proton-transporting two-sector ATPase complexGO:001646918100%0.31%3.28E-51(5.3E-48)
proton-transporting ATP synthase complex (sensu Eukaryota)GO:000575318100%0.31%3.28E-51(5.3E-48)
proton-transporting ATP synthase complex, coupling factor F(o)GO:00452631266.67%0.19%1.71E-33(2.77E-30)
proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukaryota)GO:00002761266.67%0.19%1.71E-33(2.77E-30)
mitochondrial inner membraneGO:000574318100%2.43%3.29E-30(5.32E-27)
inner membraneGO:001986618100%2.43%3.29E-30(5.32E-27)
mitochondrial membraneGO:000574018100%3.16%4.66E-28(7.54E-25)
integral to membraneGO:001602118100%3.55%4.08E-27(6.59E-24)
intrinsic to membraneGO:003122418100%3.61%5.63E-27(9.1E-24)
organelle membraneGO:003109018100%8.58%4.93E-20(7.97E-17)
membraneGO:001602018100%15.38%2.04E-15(3.29E-12)
mitochondrionGO:000573918100%15.78%3.25E-15(5.26E-12)
proton-transporting ATP synthase complex, catalytic core F(1) (sensu Eukaryota)GO:0000275527.78%0.08%9.18E-14(1.48E-10)
proton-transporting ATP synthase complex, catalytic core F(1)GO:0045261527.78%0.08%9.18E-14(1.48E-10)
protein complexGO:004323418100%21.07%6.1E-13(9.86E-10)
proton-transporting ATP synthase, central stalk (sensu Eukaryota)GO:0005756316.67%0.05%1.82E-8(2.94E-5)
proton-transporting ATP synthase, central stalkGO:0045269316.67%0.05%1.82E-8(2.94E-5)
proton-transporting ATP synthase, stator stalkGO:0045265316.67%0.05%1.82E-8(2.94E-5)
proton-transporting ATP synthase, stator stalk (sensu Eukaryota)GO:0000274316.67%0.05%1.82E-8(2.94E-5)
proton-transporting ATP synthase, catalytic core (sensu Eukaryota)GO:0005754211.11%0.03%7.34E-6(0.01)
proton-transporting ATP synthase, catalytic coreGO:0045267211.11%0.03%7.34E-6(0.01)
cytoplasmGO:000573718100%55.64%2.56E-5(0.04)
intracellular membrane-bound organelleGO:004323118100%55.65%2.57E-5(0.04)
membrane-bound organelleGO:004322718100%55.65%2.57E-5(0.04)
organelleGO:004322618100%60.56%1.18E-4(0.19)
intracellular organelleGO:004322918100%60.56%1.18E-4(0.19)
intracellularGO:000562218100%77.03%9.05E-3(n.s)
cellGO:000562318100%83.5%0.04(n.s)
nucleoidGO:000929515.56%0.36%0.06(n.s)
mitochondrial nucleoidGO:004264515.56%0.36%0.06(n.s)
soluble fractionGO:000562515.56%0.56%0.1(n.s)
cell fractionGO:000026715.56%1.72%0.27(n.s)
mitochondrial matrixGO:000575915.56%2.52%0.37(n.s)
cellular_componentGO:000557518100%99.61%0.93(n.s)

 

 

cluster_156 (n = 10)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial electron transport, ubiquinol to cytochrome cGO:0006122990%0.14%1.87E-28(3.03E-25)
ATP synthesis coupled electron transportGO:0042773990%0.39%3.82E-22(6.17E-19)
ATP synthesis coupled electron transport (sensu Eukaryota)GO:0042775990%0.39%3.82E-22(6.17E-19)
electron transportGO:0006118990%0.48%3.76E-21(6.08E-18)
oxidative phosphorylationGO:0006119990%0.71%2.05E-19(3.32E-16)
aerobic respirationGO:0009060990%1.27%5.43E-17(8.78E-14)
cellular respirationGO:0045333990%1.35%9.5E-17(1.54E-13)
generation of precursor metabolites and energyGO:000609110100%3.5%2.27E-15(3.67E-12)
phosphorylationGO:0016310990%2.21%9.8E-15(1.58E-11)
phosphate metabolismGO:0006796990%2.91%1.22E-13(1.96E-10)
phosphorus metabolismGO:0006793990%2.91%1.22E-13(1.96E-10)
energy derivation by oxidation of organic compoundsGO:0015980990%3.04%1.78E-13(2.88E-10)
transportGO:0006810990%14.27%2.06E-7(3.34E-4)
establishment of localizationGO:0051234990%14.39%2.23E-7(3.6E-4)
localizationGO:0051179990%14.82%2.9E-7(4.69E-4)
cellular metabolismGO:004423710100%52.12%1.47E-3(n.s)
cytochrome bc(1) complex assemblyGO:0017062110%0.02%**
metabolismGO:000815210100%52.93%1.71E-3(n.s)
cytochrome complex assemblyGO:0017004110%0.08%7.72E-3(n.s)
iron-sulfur cluster assemblyGO:0016226110%0.14%0.01(n.s)
metallo-sulfur cluster assemblyGO:0031163110%0.14%0.01(n.s)
cellular physiological processGO:005087510100%71.65%0.04(n.s)
cellular processGO:000998710100%72.29%0.04(n.s)
physiological processGO:000758210100%73.68%0.05(n.s)
protein complex assemblyGO:0006461110%2.26%0.2(n.s)
cofactor metabolismGO:0051186110%2.26%0.2(n.s)
cellular protein metabolismGO:0044267110%21.7%0.91(n.s)
protein metabolismGO:0019538110%22.06%0.92(n.s)
cellular macromolecule metabolismGO:0044260110%24.52%0.94(n.s)
macromolecule metabolismGO:0043170110%26.04%0.95(n.s)
biological_processGO:000815010100%99.98%1(n.s)
primary metabolismGO:0044238110%48.71%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ubiquinol-cytochrome-c reductase activityGO:0008121990%0.14%1.87E-28(3.03E-25)
oxidoreductase activity, acting on diphenols and related substances as donorsGO:0016679990%0.14%1.87E-28(3.03E-25)
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptorGO:0016681990%0.14%1.87E-28(3.03E-25)
primary active transporter activityGO:0015399990%0.77%4.67E-19(7.54E-16)
hydrogen ion transporter activityGO:0015078990%0.84%9.9E-19(1.6E-15)
monovalent inorganic cation transporter activityGO:0015077990%0.88%1.67E-18(2.7E-15)
carrier activityGO:0005386990%1.64%6.07E-16(9.8E-13)
cation transporter activityGO:0008324990%1.89%2.25E-15(3.63E-12)
ion transporter activityGO:0015075990%2.21%9.8E-15(1.58E-11)
oxidoreductase activityGO:0016491990%3.73%1.18E-12(1.9E-9)
transporter activityGO:000521510100%6.64%1.52E-12(2.46E-9)
catalytic activityGO:0003824990%29.21%1.13E-4(0.18)
electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activityGO:0045153110%0.02%**
electron transporter activityGO:0005489110%0.34%0.03(n.s)
molecular_functionGO:000367410100%99.44%0.95(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
respiratory chain complex IIIGO:004527510100%0.15%2.91E-32(4.69E-29)
respiratory chain complex III (sensu Eukaryota)GO:000575010100%0.15%2.91E-32(4.69E-29)
mitochondrial electron transport chainGO:000574610100%0.4%1.54E-25(2.49E-22)
mitochondrial inner membraneGO:000574310100%2.43%5.44E-17(8.79E-14)
inner membraneGO:001986610100%2.43%5.44E-17(8.79E-14)
mitochondrial membraneGO:000574010100%3.16%7.99E-16(1.29E-12)
organelle membraneGO:003109010100%8.58%2.01E-11(3.25E-8)
membraneGO:001602010100%15.38%7.13E-9(1.15E-5)
mitochondrionGO:000573910100%15.78%9.24E-9(1.49E-5)
protein complexGO:004323410100%21.07%1.68E-7(2.71E-4)
cytoplasmGO:000573710100%55.64%2.83E-3(n.s)
intracellular membrane-bound organelleGO:004323110100%55.65%2.83E-3(n.s)
membrane-bound organelleGO:004322710100%55.65%2.83E-3(n.s)
organelleGO:004322610100%60.56%6.61E-3(n.s)
intracellular organelleGO:004322910100%60.56%6.61E-3(n.s)
intracellularGO:000562210100%77.03%0.07(n.s)
cellGO:000562310100%83.5%0.16(n.s)
cellular_componentGO:000557510100%99.61%0.96(n.s)

 

 

cluster_48 (n = 8)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
polyol metabolismGO:0019751225%0.12%3.75E-5(0.06)
glycerol metabolismGO:0006071225%0.12%3.75E-5(0.06)
lipid biosynthesisGO:0008610337.5%1.92%3.61E-4(0.58)
intracellular accumulation of glycerolGO:0006973112.5%0.02%**
phosphatidylglycerol biosynthesisGO:0006655112.5%0.02%**
phosphatidylglycerol metabolismGO:0046471112.5%0.02%**
cellular lipid metabolismGO:0044255337.5%3.16%1.55E-3(n.s)
phospholipid biosynthesisGO:0008654225%0.81%1.73E-3(n.s)
lipid metabolismGO:0006629337.5%3.38%1.88E-3(n.s)
membrane lipid biosynthesisGO:0046467225%1.1%3.2E-3(n.s)
phosphatidylserine metabolismGO:0006658112.5%0.05%3.71E-3(n.s)
NADH oxidationGO:0006116112.5%0.05%3.71E-3(n.s)
phospholipid metabolismGO:0006644225%1.19%3.75E-3(n.s)
membrane lipid metabolismGO:0006643225%1.61%6.76E-3(n.s)
NADH metabolismGO:0006734112.5%0.09%7.41E-3(n.s)
hyperosmotic responseGO:0006972112.5%0.11%8.65E-3(n.s)
alcohol metabolismGO:0006066225%2.43%0.01(n.s)
NAD metabolismGO:0019674112.5%0.22%0.02(n.s)
mitochondrial membrane organization and biogenesisGO:0007006112.5%0.29%0.02(n.s)
nicotinamide metabolismGO:0006769112.5%0.46%0.04(n.s)
membrane organization and biogenesisGO:0016044112.5%0.48%0.04(n.s)
pyridine nucleotide metabolismGO:0019362112.5%0.51%0.04(n.s)
glycerophospholipid biosynthesisGO:0046474112.5%0.53%0.04(n.s)
oxidoreduction coenzyme metabolismGO:0006733112.5%0.67%0.05(n.s)
glycerophospholipid metabolismGO:0006650112.5%0.68%0.05(n.s)
response to osmotic stressGO:0006970112.5%0.91%0.07(n.s)
vitamin metabolismGO:0006766112.5%1.13%0.09(n.s)
water-soluble vitamin metabolismGO:0006767112.5%1.13%0.09(n.s)
nucleotide metabolismGO:0009117112.5%1.38%0.11(n.s)
mitochondrion organization and biogenesisGO:0007005112.5%1.47%0.11(n.s)
coenzyme metabolismGO:0006732112.5%1.81%0.14(n.s)
biosynthesisGO:0009058337.5%18.28%0.17(n.s)
cofactor metabolismGO:0051186112.5%2.26%0.17(n.s)
cellular metabolismGO:0044237675%52.12%0.17(n.s)
metabolismGO:0008152675%52.93%0.19(n.s)
carbohydrate metabolismGO:0005975112.5%3.38%0.24(n.s)
response to abiotic stimulusGO:0009628112.5%3.52%0.25(n.s)
response to external stimulusGO:0009605112.5%3.87%0.27(n.s)
physiological processGO:0007582787.5%73.68%0.33(n.s)
response to stressGO:0006950112.5%6.09%0.4(n.s)
response to stimulusGO:0050896112.5%8.41%0.51(n.s)
cellular physiological processGO:0050875675%71.65%0.59(n.s)
primary metabolismGO:0044238450%48.71%0.61(n.s)
cellular processGO:0009987675%72.29%0.61(n.s)
organelle organization and biogenesisGO:0006996112.5%15.69%0.74(n.s)
cell organization and biogenesisGO:0016043112.5%17.98%0.8(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139112.5%23.17%0.88(n.s)
biological process unknownGO:0000004112.5%25.64%0.91(n.s)
macromolecule metabolismGO:0043170112.5%26.04%0.91(n.s)
biological_processGO:00081508100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glycerol-3-phosphate dehydrogenase (NAD+) activityGO:0004367225%0.03%1.34E-6(2.17E-3)
phosphotransferase activity, for other substituted phosphate groupsGO:0016780225%0.15%6.02E-5(0.1)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614337.5%1.18%8.42E-5(0.14)
transferase activity, transferring phosphorus-containing groupsGO:0016772450%5.19%4.22E-4(0.68)
catalytic activityGO:0003824787.5%29.21%1.07E-3(n.s)
phosphatidyltransferase activityGO:0030572112.5%0.02%**
phosphatidate cytidylyltransferase activityGO:0004605112.5%0.02%**
glycerol-3-phosphate dehydrogenase activityGO:0004368112.5%0.02%**
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activityGO:0008444112.5%0.02%**
cardiolipin synthase activityGO:0008808112.5%0.02%**
glycerol kinase activityGO:0004370112.5%0.02%**
oxidoreductase activityGO:0016491337.5%3.73%2.5E-3(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616225%1.07%3.02E-3(n.s)
transferase activityGO:0016740450%10.13%5.23E-3(n.s)
CDP-alcohol phosphatidyltransferase activityGO:0017169112.5%0.08%6.18E-3(n.s)
nucleotidyltransferase activityGO:0016779112.5%1.91%0.14(n.s)
phosphotransferase activity, alcohol group as acceptorGO:0016773112.5%2.62%0.19(n.s)
kinase activityGO:0016301112.5%3.05%0.22(n.s)
molecular_functionGO:00036748100%99.44%0.96(n.s)
molecular function unknownGO:0005554112.5%35.75%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739675%15.78%3.2E-4(0.52)
cytoplasmGO:00057378100%55.64%9.15E-3(n.s)
peroxisomeGO:0005777112.5%0.87%0.07(n.s)
microbodyGO:0042579112.5%0.87%0.07(n.s)
intracellular membrane-bound organelleGO:0043231787.5%55.65%0.07(n.s)
membrane-bound organelleGO:0043227787.5%55.65%0.07(n.s)
endoplasmic reticulumGO:0005783225%5.84%0.08(n.s)
organelleGO:0043226787.5%60.56%0.11(n.s)
intracellular organelleGO:0043229787.5%60.56%0.11(n.s)
intracellularGO:00056228100%77.03%0.12(n.s)
cytosolGO:0005829225%10.08%0.19(n.s)
mitochondrial membraneGO:0005740112.5%3.16%0.23(n.s)
cellGO:00056238100%83.5%0.24(n.s)
organelle membraneGO:0031090112.5%8.58%0.51(n.s)
membraneGO:0016020112.5%15.38%0.74(n.s)
cellular_componentGO:00055758100%99.61%0.97(n.s)

 

 

cluster_49 (n = 11)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein-mitochondrial targetingGO:0006626981.82%0.73%1.39E-18(2.24E-15)
mitochondrial matrix protein importGO:0030150763.64%0.31%2.75E-16(4.44E-13)
protein importGO:0017038981.82%1.39%7.11E-16(1.15E-12)
protein targetingGO:0006605981.82%3.42%2.85E-12(4.61E-9)
outer mitochondrial membrane organization and biogenesisGO:0007008436.36%0.06%4.56E-12(7.37E-9)
intracellular protein transportGO:0006886981.82%3.7%5.81E-12(9.39E-9)
protein transportGO:0015031981.82%3.79%7.28E-12(1.18E-8)
establishment of protein localizationGO:0045184981.82%3.95%1.05E-11(1.69E-8)
protein localizationGO:0008104981.82%4.37%2.6E-11(4.21E-8)
mitochondrial membrane organization and biogenesisGO:0007006545.45%0.29%5.69E-11(9.2E-8)
membrane organization and biogenesisGO:0016044545.45%0.48%8.24E-10(1.33E-6)
intracellular transportGO:0046907981.82%7.53%3.47E-9(5.61E-6)
mitochondrial outer membrane protein importGO:0045040327.27%0.05%3.68E-9(5.95E-6)
mitochondrion organization and biogenesisGO:0007005545.45%1.47%2.67E-7(4.32E-4)
transportGO:0006810981.82%14.27%9.91E-7(1.6E-3)
establishment of localizationGO:0051234981.82%14.39%1.07E-6(1.73E-3)
localizationGO:0051179981.82%14.82%1.39E-6(2.24E-3)
mitochondrial inner membrane protein importGO:004503919.09%0.14%0.02(n.s)
organelle organization and biogenesisGO:0006996545.45%15.69%0.02(n.s)
inner mitochondrial membrane organization and biogenesisGO:000700719.09%0.2%0.02(n.s)
cell organization and biogenesisGO:0016043545.45%17.98%0.03(n.s)
cellular physiological processGO:00508751090.91%71.65%0.14(n.s)
cellular processGO:00099871090.91%72.29%0.15(n.s)
physiological processGO:00075821090.91%73.68%0.17(n.s)
protein complex assemblyGO:000646119.09%2.26%0.22(n.s)
cellular protein metabolismGO:004426719.09%21.7%0.93(n.s)
protein metabolismGO:001953819.09%22.06%0.94(n.s)
cellular macromolecule metabolismGO:004426019.09%24.52%0.95(n.s)
biological process unknownGO:000000419.09%25.64%0.96(n.s)
macromolecule metabolismGO:004317019.09%26.04%0.96(n.s)
biological_processGO:000815011100%99.98%1(n.s)
primary metabolismGO:004423819.09%48.71%1(n.s)
cellular metabolismGO:004423719.09%52.12%1(n.s)
metabolismGO:000815219.09%52.93%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein transporter activityGO:0008565872.73%0.77%1.17E-15(1.89E-12)
transporter activityGO:0005215872.73%6.64%4.93E-8(7.97E-5)
protein bindingGO:0005515218.18%7.39%0.19(n.s)
bindingGO:0005488218.18%17.35%0.59(n.s)
molecular_functionGO:000367411100%99.44%0.94(n.s)
molecular function unknownGO:000555419.09%35.75%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial outer membraneGO:000574111100%0.53%1.42E-26(2.29E-23)
outer membraneGO:001986711100%0.53%1.42E-26(2.29E-23)
mitochondrial outer membrane translocase complexGO:0005742763.64%0.11%3.57E-21(5.77E-18)
mitochondrial membraneGO:000574011100%3.16%2.4E-17(3.88E-14)
organelle membraneGO:003109011100%8.58%1.7E-12(2.74E-9)
membraneGO:001602011100%15.38%1.09E-9(1.76E-6)
mitochondrionGO:000573911100%15.78%1.45E-9(2.34E-6)
mitochondrial sorting and assembly machinery complexGO:0001401327.27%0.06%1.47E-8(2.38E-5)
protein complexGO:00432341090.91%21.07%1.49E-6(2.41E-3)
cytoplasmGO:000573711100%55.64%1.57E-3(n.s)
intracellular membrane-bound organelleGO:004323111100%55.65%1.58E-3(n.s)
membrane-bound organelleGO:004322711100%55.65%1.58E-3(n.s)
organelleGO:004322611100%60.56%4E-3(n.s)
intracellular organelleGO:004322911100%60.56%4E-3(n.s)
extrinsic to membraneGO:001989819.09%0.48%0.05(n.s)
intracellularGO:000562211100%77.03%0.06(n.s)
cellGO:000562311100%83.5%0.14(n.s)
cellular_componentGO:000557511100%99.61%0.96(n.s)

 

 

cluster_46 (n = 10)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
organic acid metabolismGO:0006082990%4.6%7.88E-12(1.27E-8)
carboxylic acid metabolismGO:0019752990%4.6%7.88E-12(1.27E-8)
folic acid and derivative metabolismGO:0006760440%0.14%3.65E-10(5.89E-7)
one-carbon compound metabolismGO:0006730440%0.19%1.43E-9(2.31E-6)
glycine catabolismGO:0006546330%0.06%1.07E-8(1.73E-5)
serine family amino acid catabolismGO:0009071330%0.08%2.67E-8(4.32E-5)
folic acid and derivative biosynthesisGO:0009396330%0.08%2.67E-8(4.32E-5)
glycine metabolismGO:0006544330%0.09%5.34E-8(8.63E-5)
group transfer coenzyme metabolismGO:0006752440%0.68%3.83E-7(6.18E-4)
aromatic compound metabolismGO:0006725440%0.88%1.1E-6(1.78E-3)
heterocycle metabolismGO:0046483440%1.1%2.68E-6(4.34E-3)
amino acid metabolismGO:0006520550%2.82%3.79E-6(6.12E-3)
serine family amino acid metabolismGO:0009069330%0.34%4.06E-6(6.56E-3)
amino acid and derivative metabolismGO:0006519550%3.05%5.6E-6(9.04E-3)
amino acid catabolismGO:0009063330%0.43%8.59E-6(0.01)
amine metabolismGO:0009308550%3.38%9.2E-6(0.01)
amine catabolismGO:0009310330%0.48%1.18E-5(0.02)
nitrogen compound catabolismGO:0044270330%0.48%1.18E-5(0.02)
nitrogen compound metabolismGO:0006807550%3.66%1.36E-5(0.02)
coenzyme metabolismGO:0006732440%1.81%1.98E-5(0.03)
cofactor metabolismGO:0051186440%2.26%4.74E-5(0.08)
coenzyme biosynthesisGO:0009108330%0.87%7.11E-5(0.11)
cofactor biosynthesisGO:0051188330%1.08%1.39E-4(0.22)
purine base metabolismGO:0006144220%0.25%2.56E-4(0.41)
methionine metabolismGO:0006555220%0.36%5.37E-4(0.87)
sulfur amino acid metabolismGO:0000096220%0.5%1.04E-3(n.s)
nucleobase metabolismGO:0009112220%0.51%1.11E-3(n.s)
cellular metabolismGO:004423710100%52.12%1.47E-3(n.s)
pteridine and derivative biosynthesisGO:0042559110%0.02%**
nitrogenous compound fermentationGO:0019666110%0.02%**
purine fermentationGO:0019653110%0.02%**
conversion of met-tRNAf to fmet-tRNAGO:0001718110%0.02%**
folic acid biosynthesisGO:0046656110%0.02%**
acetate biosynthesis from carbon monoxideGO:0019415110%0.02%**
metabolismGO:000815210100%52.93%1.71E-3(n.s)
aspartate family amino acid metabolismGO:0009066220%0.7%2.06E-3(n.s)
folic acid metabolismGO:0046655110%0.03%3.1E-3(n.s)
charged-tRNA modificationGO:0019988110%0.03%3.1E-3(n.s)
pteridine and derivative metabolismGO:0042558110%0.03%3.1E-3(n.s)
sulfur metabolismGO:0006790220%0.87%3.18E-3(n.s)
acetate biosynthesisGO:0019413110%0.06%6.18E-3(n.s)
purine base biosynthesisGO:0009113110%0.09%9.26E-3(n.s)
acetate metabolismGO:0006083110%0.11%0.01(n.s)
sulfur amino acid biosynthesisGO:0000097110%0.14%0.01(n.s)
cellular biosynthesisGO:0044249550%17.05%0.02(n.s)
cellular catabolismGO:0044248330%5.84%0.02(n.s)
catabolismGO:0009056330%6.16%0.02(n.s)
biosynthesisGO:0009058550%18.28%0.02(n.s)
sulfur compound biosynthesisGO:0044272110%0.23%0.02(n.s)
fermentationGO:0006113110%0.25%0.02(n.s)
organic acid biosynthesisGO:0016053110%0.26%0.03(n.s)
carboxylic acid biosynthesisGO:0046394110%0.26%0.03(n.s)
aromatic compound biosynthesisGO:0019438110%0.26%0.03(n.s)
nucleobase biosynthesisGO:0046112110%0.33%0.03(n.s)
cellular physiological processGO:005087510100%71.65%0.04(n.s)
cellular processGO:000998710100%72.29%0.04(n.s)
physiological processGO:000758210100%73.68%0.05(n.s)
vitamin biosynthesisGO:0009110110%0.59%0.06(n.s)
water-soluble vitamin biosynthesisGO:0042364110%0.59%0.06(n.s)
translational initiationGO:0006413110%0.74%0.07(n.s)
tRNA modificationGO:0006400110%1.02%0.1(n.s)
vitamin metabolismGO:0006766110%1.13%0.11(n.s)
water-soluble vitamin metabolismGO:0006767110%1.13%0.11(n.s)
amino acid biosynthesisGO:0008652110%1.53%0.14(n.s)
tRNA metabolismGO:0006399110%1.6%0.15(n.s)
primary metabolismGO:0044238770%48.71%0.15(n.s)
amine biosynthesisGO:0009309110%1.67%0.16(n.s)
nitrogen compound biosynthesisGO:0044271110%1.67%0.16(n.s)
RNA modificationGO:0009451110%2.42%0.22(n.s)
energy derivation by oxidation of organic compoundsGO:0015980110%3.04%0.27(n.s)
generation of precursor metabolites and energyGO:0006091110%3.5%0.3(n.s)
translationGO:0043037110%6.47%0.49(n.s)
RNA metabolismGO:0016070110%8.32%0.58(n.s)
biopolymer modificationGO:0043412110%9.25%0.62(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139220%23.17%0.71(n.s)
protein biosynthesisGO:0006412110%12.16%0.73(n.s)
macromolecule biosynthesisGO:0009059110%13.04%0.75(n.s)
cellular protein metabolismGO:0044267110%21.7%0.91(n.s)
protein metabolismGO:0019538110%22.06%0.92(n.s)
cellular macromolecule metabolismGO:0044260110%24.52%0.94(n.s)
biopolymer metabolismGO:0043283110%25.06%0.94(n.s)
macromolecule metabolismGO:0043170110%26.04%0.95(n.s)
biological_processGO:000815010100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptorGO:0016646440%0.19%1.43E-9(2.31E-6)
oxidoreductase activity, acting on the CH-NH group of donorsGO:0016645440%0.22%2.89E-9(4.66E-6)
methylenetetrahydrofolate reductase (NADPH) activityGO:0004489220%0.03%2.16E-6(3.49E-3)
methylenetetrahydrofolate dehydrogenase (NADP+) activityGO:0004488220%0.03%2.16E-6(3.49E-3)
methenyltetrahydrofolate cyclohydrolase activityGO:0004477220%0.03%2.16E-6(3.49E-3)
formate-tetrahydrofolate ligase activityGO:0004329220%0.03%2.16E-6(3.49E-3)
methylenetetrahydrofolate dehydrogenase activityGO:0004486220%0.05%6.47E-6(0.01)
cyclohydrolase activityGO:0019238220%0.11%4.52E-5(0.07)
ligase activity, forming carbon-nitrogen bondsGO:0016879330%1.07%1.33E-4(0.21)
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidinesGO:0016814220%0.26%2.9E-4(0.47)
oxidoreductase activityGO:0016491440%3.73%3.33E-4(0.54)
ligase activityGO:0016874330%1.89%7.17E-4(n.s)
5-formyltetrahydrofolate cyclo-ligase activityGO:0030272110%0.02%**
dihydropteroate synthase activityGO:0004156110%0.02%**
dihydroneopterin aldolase activityGO:0004150110%0.02%**
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activityGO:0003848110%0.02%**
hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsGO:0016810220%0.93%3.64E-3(n.s)
cyclo-ligase activityGO:0016882110%0.05%4.64E-3(n.s)
aldehyde-lyase activityGO:0016832110%0.06%6.18E-3(n.s)
catalytic activityGO:0003824770%29.21%8.99E-3(n.s)
glycine hydroxymethyltransferase activityGO:0004372110%0.11%0.01(n.s)
diphosphotransferase activityGO:0016778110%0.11%0.01(n.s)
carbon-carbon lyase activityGO:0016830110%0.43%0.04(n.s)
transferase activity, transferring alkyl or aryl (other than methyl) groupsGO:0016765110%0.53%0.05(n.s)
methyltransferase activityGO:0008168110%1.1%0.1(n.s)
transferase activity, transferring one-carbon groupsGO:0016741110%1.13%0.11(n.s)
lyase activityGO:0016829110%1.27%0.12(n.s)
kinase activityGO:0016301110%3.05%0.27(n.s)
transferase activityGO:0016740220%10.13%0.27(n.s)
structural constituent of ribosomeGO:0003735110%3.58%0.31(n.s)
hydrolase activityGO:0016787220%11.45%0.32(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772110%5.19%0.41(n.s)
structural molecule activityGO:0005198110%5.51%0.43(n.s)
molecular_functionGO:0003674770%99.44%1(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glycine cleavage complexGO:0005960330%0.06%1.07E-8(1.73E-5)
mitochondrionGO:0005739880%15.78%1.25E-5(0.02)
cytoplasmGO:000573710100%55.64%2.83E-3(n.s)
intracellular membrane-bound organelleGO:0043231990%55.65%0.03(n.s)
membrane-bound organelleGO:0043227990%55.65%0.03(n.s)
organelleGO:0043226990%60.56%0.05(n.s)
intracellular organelleGO:0043229990%60.56%0.05(n.s)
intracellularGO:000562210100%77.03%0.07(n.s)
cellGO:000562310100%83.5%0.16(n.s)
mitochondrial membraneGO:0005740110%3.16%0.27(n.s)
protein complexGO:0043234330%21.07%0.35(n.s)
organelle membraneGO:0031090110%8.58%0.59(n.s)
membraneGO:0016020110%15.38%0.81(n.s)
cellular_componentGO:000557510100%99.61%0.96(n.s)
nucleusGO:0005634110%31.01%0.98(n.s)

 

 

cluster_45 (n = 8)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cellular lipid metabolismGO:0044255450%3.16%6.13E-5(0.1)
lipid metabolismGO:0006629450%3.38%7.96E-5(0.13)
phospholipid metabolismGO:0006644337.5%1.19%8.75E-5(0.14)
MAPKKK cascadeGO:0000165225%0.26%1.81E-4(0.29)
membrane lipid metabolismGO:0006643337.5%1.61%2.14E-4(0.35)
protein kinase cascadeGO:0007243225%0.31%2.52E-4(0.41)
lipid biosynthesisGO:0008610337.5%1.92%3.61E-4(0.58)
phospholipid biosynthesisGO:0008654225%0.81%1.73E-3(n.s)
membrane lipid biosynthesisGO:0046467225%1.1%3.2E-3(n.s)
phosphoinositide phosphorylationGO:0046854112.5%0.06%4.95E-3(n.s)
lipid phosphorylationGO:0046834112.5%0.06%4.95E-3(n.s)
ethanolamine and derivative metabolismGO:0042439112.5%0.08%6.18E-3(n.s)
phosphatidylethanolamine metabolismGO:0046337112.5%0.08%6.18E-3(n.s)
ethanolamine metabolismGO:0006580112.5%0.08%6.18E-3(n.s)
ethanolamine biosynthesisGO:0046335112.5%0.08%6.18E-3(n.s)
phosphatidylethanolamine biosynthesisGO:0006646112.5%0.08%6.18E-3(n.s)
intracellular signaling cascadeGO:0007242225%1.66%7.14E-3(n.s)
myo-inositol metabolismGO:0006020112.5%0.09%7.41E-3(n.s)
negative regulation of transcription, DNA-dependentGO:0045892225%1.89%9.21E-3(n.s)
negative regulation of transcriptionGO:0016481225%1.95%9.8E-3(n.s)
protein secretionGO:0009306112.5%0.14%0.01(n.s)
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045934225%2.11%0.01(n.s)
negative regulation of cellular metabolismGO:0031324225%2.29%0.01(n.s)
negative regulation of metabolismGO:0009892225%2.4%0.01(n.s)
lipid modificationGO:0030258112.5%0.19%0.01(n.s)
alcohol metabolismGO:0006066225%2.43%0.01(n.s)
phosphoinositide-mediated signalingGO:0048015112.5%0.2%0.02(n.s)
inositol lipid-mediated signalingGO:0048017112.5%0.2%0.02(n.s)
signal transductionGO:0007165225%2.59%0.02(n.s)
negative regulation of cellular physiological processGO:0051243225%2.59%0.02(n.s)
negative regulation of cellular processGO:0048523225%2.59%0.02(n.s)
negative regulation of physiological processGO:0043118225%2.62%0.02(n.s)
negative regulation of biological processGO:0048519225%2.71%0.02(n.s)
nuclear migration, microtubule-mediatedGO:0030473112.5%0.23%0.02(n.s)
microtubule-based movementGO:0007018112.5%0.23%0.02(n.s)
cytoskeleton-dependent intracellular transportGO:0030705112.5%0.25%0.02(n.s)
response to heatGO:0009408112.5%0.26%0.02(n.s)
biogenic amine biosynthesisGO:0042401112.5%0.29%0.02(n.s)
cell communicationGO:0007154225%3.08%0.02(n.s)
amino acid derivative biosynthesisGO:0042398112.5%0.31%0.02(n.s)
nuclear positioningGO:0040023112.5%0.31%0.02(n.s)
response to temperatureGO:0009266112.5%0.31%0.02(n.s)
nuclear migrationGO:0007097112.5%0.31%0.02(n.s)
organelle organization and biogenesisGO:0006996450%15.69%0.02(n.s)
secretionGO:0046903225%3.24%0.03(n.s)
biogenic amine metabolismGO:0006576112.5%0.39%0.03(n.s)
amino acid derivative metabolismGO:0006575112.5%0.42%0.03(n.s)
protein-ER targetingGO:0045047112.5%0.43%0.03(n.s)
second-messenger-mediated signalingGO:0019932112.5%0.43%0.03(n.s)
establishment of protein localizationGO:0045184225%3.95%0.04(n.s)
phosphoinositide metabolismGO:0030384112.5%0.48%0.04(n.s)
cell organization and biogenesisGO:0016043450%17.98%0.04(n.s)
steroid biosynthesisGO:0006694112.5%0.56%0.04(n.s)
protein localizationGO:0008104225%4.37%0.04(n.s)
vacuole organization and biogenesisGO:0007033112.5%0.59%0.05(n.s)
cytoskeleton organization and biogenesisGO:0007010225%4.48%0.05(n.s)
negative regulation of transcription from RNA polymerase II promoterGO:0000122112.5%0.64%0.05(n.s)
regulation of transcription, DNA-dependentGO:0006355225%4.68%0.05(n.s)
telomeric heterochromatin formationGO:0031509112.5%0.67%0.05(n.s)
chromatin silencing at telomereGO:0006348112.5%0.67%0.05(n.s)
glycerophospholipid metabolismGO:0006650112.5%0.68%0.05(n.s)
steroid metabolismGO:0008202112.5%0.7%0.05(n.s)
regulation of transcriptionGO:0045449225%4.96%0.06(n.s)
positive regulation of transcription from RNA polymerase II promoterGO:0045944112.5%0.74%0.06(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219225%5.24%0.06(n.s)
positive regulation of transcription, DNA-dependentGO:0045893112.5%0.91%0.07(n.s)
positive regulation of transcriptionGO:0045941112.5%1.01%0.08(n.s)
nuclear organization and biogenesisGO:0006997112.5%1.01%0.08(n.s)
regulation of cellular metabolismGO:0031323225%5.98%0.08(n.s)
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045935112.5%1.02%0.08(n.s)
response to stressGO:0006950225%6.09%0.08(n.s)
positive regulation of cellular metabolismGO:0031325112.5%1.05%0.08(n.s)
positive regulation of metabolismGO:0009893112.5%1.05%0.08(n.s)
positive regulation of physiological processGO:0043119112.5%1.1%0.08(n.s)
positive regulation of cellular processGO:0048522112.5%1.1%0.08(n.s)
positive regulation of cellular physiological processGO:0051242112.5%1.1%0.08(n.s)
regulation of metabolismGO:0019222225%6.37%0.09(n.s)
negative regulation of gene expression, epigeneticGO:0045814112.5%1.19%0.09(n.s)
chromatin silencingGO:0006342112.5%1.19%0.09(n.s)
gene silencingGO:0016458112.5%1.19%0.09(n.s)
heterochromatin formationGO:0031507112.5%1.19%0.09(n.s)
positive regulation of biological processGO:0048518112.5%1.21%0.09(n.s)
establishment of localizationGO:0051234337.5%14.39%0.1(n.s)
regulation of gene expression, epigeneticGO:0040029112.5%1.27%0.1(n.s)
chromatin assemblyGO:0031497112.5%1.27%0.1(n.s)
transcription, DNA-dependentGO:0006351225%6.78%0.1(n.s)
microtubule cytoskeleton organization and biogenesisGO:0000226112.5%1.32%0.1(n.s)
hexose metabolismGO:0019318112.5%1.32%0.1(n.s)
localizationGO:0051179337.5%14.82%0.1(n.s)
monosaccharide metabolismGO:0005996112.5%1.43%0.11(n.s)
transcriptionGO:0006350225%7.43%0.11(n.s)
chromatin assembly or disassemblyGO:0006333112.5%1.52%0.12(n.s)
intracellular transportGO:0046907225%7.53%0.12(n.s)
microtubule-based processGO:0007017112.5%1.55%0.12(n.s)
actin cytoskeleton organization and biogenesisGO:0030036112.5%1.55%0.12(n.s)
actin filament-based processGO:0030029112.5%1.61%0.12(n.s)
amine biosynthesisGO:0009309112.5%1.67%0.13(n.s)
nitrogen compound biosynthesisGO:0044271112.5%1.67%0.13(n.s)
response to stimulusGO:0050896225%8.41%0.14(n.s)
regulation of cellular physiological processGO:0051244225%8.49%0.14(n.s)
regulation of cellular processGO:0050794225%8.52%0.14(n.s)
chromatin remodelingGO:0006338112.5%2.01%0.15(n.s)
regulation of physiological processGO:0050791225%8.77%0.15(n.s)
regulation of biological processGO:0050789225%8.97%0.16(n.s)
phosphorylationGO:0016310112.5%2.21%0.16(n.s)
biosynthesisGO:0009058337.5%18.28%0.17(n.s)
chromatin modificationGO:0016568112.5%2.77%0.2(n.s)
regulation of transcription from RNA polymerase II promoterGO:0006357112.5%2.8%0.2(n.s)
phosphorus metabolismGO:0006793112.5%2.91%0.21(n.s)
phosphate metabolismGO:0006796112.5%2.91%0.21(n.s)
amino acid and derivative metabolismGO:0006519112.5%3.05%0.22(n.s)
cellular carbohydrate metabolismGO:0044262112.5%3.08%0.22(n.s)
secretory pathwayGO:0045045112.5%3.13%0.22(n.s)
DNA packagingGO:0006323112.5%3.14%0.23(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325112.5%3.14%0.23(n.s)
amine metabolismGO:0009308112.5%3.38%0.24(n.s)
carbohydrate metabolismGO:0005975112.5%3.38%0.24(n.s)
protein targetingGO:0006605112.5%3.42%0.24(n.s)
response to abiotic stimulusGO:0009628112.5%3.52%0.25(n.s)
nitrogen compound metabolismGO:0006807112.5%3.66%0.26(n.s)
intracellular protein transportGO:0006886112.5%3.7%0.26(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001112.5%3.72%0.26(n.s)
protein transportGO:0015031112.5%3.79%0.27(n.s)
response to external stimulusGO:0009605112.5%3.87%0.27(n.s)
chromosome organization and biogenesisGO:0051276112.5%3.9%0.27(n.s)
transcription from RNA polymerase II promoterGO:0006366112.5%4.29%0.3(n.s)
cellular processGO:0009987787.5%72.29%0.3(n.s)
transportGO:0006810225%14.27%0.32(n.s)
physiological processGO:0007582787.5%73.68%0.33(n.s)
primary metabolismGO:0044238562.5%48.71%0.34(n.s)
developmentGO:0007275112.5%5.73%0.38(n.s)
cellular metabolismGO:0044237562.5%52.12%0.41(n.s)
metabolismGO:0008152562.5%52.93%0.43(n.s)
DNA metabolismGO:0006259112.5%8.58%0.51(n.s)
biopolymer modificationGO:0043412112.5%9.25%0.54(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139225%23.17%0.59(n.s)
cellular physiological processGO:0050875675%71.65%0.59(n.s)
biopolymer metabolismGO:0043283225%25.06%0.63(n.s)
cellular biosynthesisGO:0044249112.5%17.05%0.78(n.s)
cellular macromolecule metabolismGO:0044260112.5%24.52%0.89(n.s)
macromolecule metabolismGO:0043170112.5%26.04%0.91(n.s)
biological_processGO:00081508100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lipid kinase activityGO:0001727225%0.12%3.75E-5(0.06)
inositol or phosphatidylinositol kinase activityGO:0004428225%0.17%7.35E-5(0.12)
1-phosphatidylinositol-3-phosphate 5-kinase activityGO:0000285112.5%0.02%**
phosphatidylinositol phosphate kinase activityGO:0016307112.5%0.03%2.48E-3(n.s)
1-phosphatidylinositol 4-kinase activityGO:0004430112.5%0.05%3.71E-3(n.s)
oxysterol bindingGO:0008142112.5%0.09%7.41E-3(n.s)
steroid bindingGO:0005496112.5%0.09%7.41E-3(n.s)
protein kinase inhibitor activityGO:0004860112.5%0.09%7.41E-3(n.s)
kinase inhibitor activityGO:0019210112.5%0.11%8.65E-3(n.s)
protein bindingGO:0005515337.5%7.39%0.02(n.s)
phosphotransferase activity, alcohol group as acceptorGO:0016773225%2.62%0.02(n.s)
transcription corepressor activityGO:0003714112.5%0.25%0.02(n.s)
tubulin bindingGO:0015631112.5%0.26%0.02(n.s)
kinase activityGO:0016301225%3.05%0.02(n.s)
enzyme inhibitor activityGO:0004857112.5%0.34%0.03(n.s)
bindingGO:0005488450%17.35%0.04(n.s)
transferase activityGO:0016740337.5%10.13%0.04(n.s)
transcription cofactor activityGO:0003712112.5%0.56%0.04(n.s)
protein kinase regulator activityGO:0019887112.5%0.56%0.04(n.s)
kinase regulator activityGO:0019207112.5%0.6%0.05(n.s)
transcription factor bindingGO:0008134112.5%0.6%0.05(n.s)
cytoskeletal protein bindingGO:0008092112.5%0.74%0.06(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772225%5.19%0.06(n.s)
enzyme regulator activityGO:0030234112.5%2.54%0.19(n.s)
transcription regulator activityGO:0030528112.5%5%0.34(n.s)
catalytic activityGO:0003824337.5%29.21%0.43(n.s)
molecular_functionGO:00036748100%99.44%0.96(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
plasma membraneGO:0005886337.5%3.67%2.39E-3(n.s)
membraneGO:0016020562.5%15.38%3.18E-3(n.s)
budGO:0005933225%2.12%0.01(n.s)
site of polarized growthGO:0030427225%2.21%0.01(n.s)
mitochondrionGO:0005739450%15.78%0.03(n.s)
bud tipGO:0005934112.5%0.74%0.06(n.s)
cell cortexGO:0005938112.5%1.52%0.12(n.s)
vacuolar membraneGO:0005774112.5%1.55%0.12(n.s)
bud neckGO:0005935112.5%1.64%0.12(n.s)
vacuoleGO:0005773112.5%2.97%0.21(n.s)
cytoplasmGO:0005737675%55.64%0.23(n.s)
intracellular membrane-bound organelleGO:0043231675%55.65%0.23(n.s)
membrane-bound organelleGO:0043227675%55.65%0.23(n.s)
cellGO:00056238100%83.5%0.24(n.s)
integral to membraneGO:0016021112.5%3.55%0.25(n.s)
intrinsic to membraneGO:0031224112.5%3.61%0.25(n.s)
organelleGO:0043226675%60.56%0.33(n.s)
intracellular organelleGO:0043229675%60.56%0.33(n.s)
endoplasmic reticulumGO:0005783112.5%5.84%0.38(n.s)
intracellularGO:0005622787.5%77.03%0.42(n.s)
organelle membraneGO:0031090112.5%8.58%0.51(n.s)
nucleusGO:0005634112.5%31.01%0.95(n.s)
cellular_componentGO:00055758100%99.61%0.97(n.s)

 

 

cluster_41 (n = 8)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA replicationGO:0006260450%1.6%4.07E-6(6.58E-3)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139787.5%23.17%2.27E-4(0.37)
DNA metabolismGO:0006259450%8.58%2.84E-3(n.s)
nucleotide metabolismGO:0009117225%1.38%4.99E-3(n.s)
cellular metabolismGO:00442378100%52.12%5.43E-3(n.s)
metabolismGO:00081528100%52.93%6.13E-3(n.s)
G1/S-specific transcription in mitotic cell cycleGO:0000083112.5%0.19%0.01(n.s)
primary metabolismGO:0044238787.5%48.71%0.03(n.s)
G1/S transition of mitotic cell cycleGO:0000082112.5%0.85%0.07(n.s)
cellular physiological processGO:00508758100%71.65%0.07(n.s)
cellular processGO:00099878100%72.29%0.07(n.s)
physiological processGO:00075828100%73.68%0.09(n.s)
aerobic respirationGO:0009060112.5%1.27%0.1(n.s)
interphaseGO:0051325112.5%1.35%0.1(n.s)
interphase of mitotic cell cycleGO:0051329112.5%1.35%0.1(n.s)
cellular respirationGO:0045333112.5%1.35%0.1(n.s)
biopolymer metabolismGO:0043283450%25.06%0.11(n.s)
regulation of transcription from RNA polymerase II promoterGO:0006357112.5%2.8%0.2(n.s)
energy derivation by oxidation of organic compoundsGO:0015980112.5%3.04%0.22(n.s)
generation of precursor metabolites and energyGO:0006091112.5%3.5%0.25(n.s)
mitotic cell cycleGO:0000278112.5%3.59%0.25(n.s)
transcription from RNA polymerase II promoterGO:0006366112.5%4.29%0.3(n.s)
regulation of transcription, DNA-dependentGO:0006355112.5%4.68%0.32(n.s)
regulation of transcriptionGO:0045449112.5%4.96%0.33(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219112.5%5.24%0.35(n.s)
regulation of cellular metabolismGO:0031323112.5%5.98%0.39(n.s)
cell cycleGO:0007049112.5%6.12%0.4(n.s)
regulation of metabolismGO:0019222112.5%6.37%0.41(n.s)
transcription, DNA-dependentGO:0006351112.5%6.78%0.43(n.s)
transcriptionGO:0006350112.5%7.43%0.46(n.s)
regulation of cellular physiological processGO:0051244112.5%8.49%0.51(n.s)
regulation of cellular processGO:0050794112.5%8.52%0.51(n.s)
regulation of physiological processGO:0050791112.5%8.77%0.52(n.s)
regulation of biological processGO:0050789112.5%8.97%0.53(n.s)
biological_processGO:00081508100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribonucleoside-diphosphate reductase activityGO:0004748450%0.06%9.68E-13(1.56E-9)
oxidoreductase activity, acting on CH2 groups, disulfide as acceptorGO:0016728450%0.06%9.68E-13(1.56E-9)
oxidoreductase activity, acting on CH2 groupsGO:0016725450%0.08%4.84E-12(7.82E-9)
adenylate kinase activityGO:0004017225%0.03%1.34E-6(2.17E-3)
nucleotide kinase activityGO:0019201225%0.06%8.05E-6(0.01)
phosphotransferase activity, phosphate group as acceptorGO:0016776225%0.14%4.82E-5(0.08)
nucleobase, nucleoside, nucleotide kinase activityGO:0019205225%0.14%4.82E-5(0.08)
oxidoreductase activityGO:0016491450%3.73%1.18E-4(0.19)
catalytic activityGO:0003824675%29.21%9.76E-3(n.s)
transcription corepressor activityGO:0003714112.5%0.25%0.02(n.s)
kinase activityGO:0016301225%3.05%0.02(n.s)
transcription cofactor activityGO:0003712112.5%0.56%0.04(n.s)
transcription factor bindingGO:0008134112.5%0.6%0.05(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772225%5.19%0.06(n.s)
transferase activityGO:0016740225%10.13%0.19(n.s)
transcription regulator activityGO:0030528112.5%5%0.34(n.s)
protein bindingGO:0005515112.5%7.39%0.46(n.s)
bindingGO:0005488112.5%17.35%0.78(n.s)
molecular_functionGO:00036748100%99.44%0.96(n.s)
molecular function unknownGO:0005554112.5%35.75%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribonucleoside-diphosphate reductase complexGO:0005971450%0.06%9.68E-13(1.56E-9)
mitochondrionGO:0005739450%15.78%0.03(n.s)
mitochondrial intermembrane spaceGO:0005758112.5%0.39%0.03(n.s)
protein complexGO:0043234450%21.07%0.07(n.s)
cytoplasmGO:0005737787.5%55.64%0.07(n.s)
intracellular membrane-bound organelleGO:0043231787.5%55.65%0.07(n.s)
membrane-bound organelleGO:0043227787.5%55.65%0.07(n.s)
organelleGO:0043226787.5%60.56%0.11(n.s)
intracellular organelleGO:0043229787.5%60.56%0.11(n.s)
intracellularGO:00056228100%77.03%0.12(n.s)
mitochondrial inner membraneGO:0005743112.5%2.43%0.18(n.s)
inner membraneGO:0019866112.5%2.43%0.18(n.s)
mitochondrial matrixGO:0005759112.5%2.52%0.19(n.s)
mitochondrial membraneGO:0005740112.5%3.16%0.23(n.s)
cellGO:00056238100%83.5%0.24(n.s)
nucleusGO:0005634337.5%31.01%0.47(n.s)
organelle membraneGO:0031090112.5%8.58%0.51(n.s)
membraneGO:0016020112.5%15.38%0.74(n.s)
cellular_componentGO:00055758100%99.61%0.97(n.s)

 

 

cluster_9 (n = 6)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein complex assemblyGO:0006461583.33%2.26%3.26E-8(5.26E-5)
chaperone-mediated protein complex assemblyGO:0051131116.67%0.02%**
cellular protein metabolismGO:0044267583.33%21.7%2.35E-3(n.s)
protein metabolismGO:0019538583.33%22.06%2.54E-3(n.s)
cellular macromolecule metabolismGO:0044260583.33%24.52%4.21E-3(n.s)
macromolecule metabolismGO:0043170583.33%26.04%5.6E-3(n.s)
manganese ion transportGO:0006828116.67%0.11%6.49E-3(n.s)
transition metal ion transportGO:0000041116.67%0.67%0.04(n.s)
di-, tri-valent inorganic cation transportGO:0015674116.67%0.79%0.05(n.s)
metal ion transportGO:0030001116.67%0.87%0.05(n.s)
aerobic respirationGO:0009060116.67%1.27%0.07(n.s)
cellular respirationGO:0045333116.67%1.35%0.08(n.s)
cation transportGO:0006812116.67%1.36%0.08(n.s)
ion transportGO:0006811116.67%1.64%0.09(n.s)
primary metabolismGO:0044238583.33%48.71%0.1(n.s)
cellular metabolismGO:0044237583.33%52.12%0.13(n.s)
cellular physiological processGO:00508756100%71.65%0.14(n.s)
metabolismGO:0008152583.33%52.93%0.14(n.s)
cellular processGO:00099876100%72.29%0.14(n.s)
physiological processGO:00075826100%73.68%0.16(n.s)
energy derivation by oxidation of organic compoundsGO:0015980116.67%3.04%0.17(n.s)
generation of precursor metabolites and energyGO:0006091116.67%3.5%0.19(n.s)
transportGO:0006810116.67%14.27%0.6(n.s)
establishment of localizationGO:0051234116.67%14.39%0.61(n.s)
localizationGO:0051179116.67%14.82%0.62(n.s)
biological_processGO:00081506100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
unfolded protein bindingGO:0051082233.33%0.9%1.16E-3(n.s)
metallochaperone activityGO:0016530116.67%0.06%3.71E-3(n.s)
metal ion transporter activityGO:0046873116.67%0.59%0.03(n.s)
protein bindingGO:0005515233.33%7.39%0.07(n.s)
ion transporter activityGO:0015075116.67%2.21%0.13(n.s)
ATPase activityGO:0016887116.67%2.52%0.14(n.s)
nucleoside-triphosphatase activityGO:0017111116.67%3.42%0.19(n.s)
pyrophosphatase activityGO:0016462116.67%3.67%0.2(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817116.67%3.69%0.2(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818116.67%3.69%0.2(n.s)
bindingGO:0005488233.33%17.35%0.28(n.s)
transporter activityGO:0005215116.67%6.64%0.34(n.s)
hydrolase activityGO:0016787116.67%11.45%0.52(n.s)
molecular function unknownGO:0005554233.33%35.75%0.69(n.s)
catalytic activityGO:0003824116.67%29.21%0.87(n.s)
molecular_functionGO:00036746100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057396100%15.78%1.53E-5(0.02)
mitochondrial inner membraneGO:0005743350%2.43%2.67E-4(0.43)
inner membraneGO:0019866350%2.43%2.67E-4(0.43)
mitochondrial membraneGO:0005740350%3.16%5.8E-4(0.94)
mitochondrial matrixGO:0005759233.33%2.52%8.89E-3(n.s)
organelle membraneGO:0031090350%8.58%0.01(n.s)
cytoplasmGO:00057376100%55.64%0.03(n.s)
intracellular membrane-bound organelleGO:00432316100%55.65%0.03(n.s)
membrane-bound organelleGO:00432276100%55.65%0.03(n.s)
organelleGO:00432266100%60.56%0.05(n.s)
intracellular organelleGO:00432296100%60.56%0.05(n.s)
membraneGO:0016020350%15.38%0.05(n.s)
intracellularGO:00056226100%77.03%0.21(n.s)
cellGO:00056236100%83.5%0.34(n.s)
cellular_componentGO:00055756100%99.61%0.98(n.s)

 

 

cluster_147 (n = 9)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tricarboxylic acid cycleGO:0006099666.67%0.23%4.18E-15(6.75E-12)
acetyl-CoA catabolismGO:0046356666.67%0.23%4.18E-15(6.75E-12)
coenzyme catabolismGO:0009109666.67%0.26%1.03E-14(1.67E-11)
cofactor catabolismGO:0051187666.67%0.28%1.55E-14(2.5E-11)
acetyl-CoA metabolismGO:0006084666.67%0.31%3.23E-14(5.21E-11)
mitochondrial electron transport, succinate to ubiquinoneGO:0006121444.44%0.06%1.74E-12(2.82E-9)
cellular respirationGO:0045333777.78%1.35%2.23E-12(3.6E-9)
main pathways of carbohydrate metabolismGO:0006092666.67%1.08%1.07E-10(1.73E-7)
aerobic respirationGO:0009060666.67%1.27%2.84E-10(4.6E-7)
energy derivation by oxidation of organic compoundsGO:0015980777.78%3.04%7.31E-10(1.18E-6)
generation of precursor metabolites and energyGO:0006091777.78%3.5%1.99E-9(3.22E-6)
coenzyme metabolismGO:0006732666.67%1.81%2.5E-9(4.05E-6)
cofactor metabolismGO:0051186666.67%2.26%9.59E-9(1.55E-5)
ATP synthesis coupled electron transportGO:0042773444.44%0.39%2.18E-8(3.52E-5)
ATP synthesis coupled electron transport (sensu Eukaryota)GO:0042775444.44%0.39%2.18E-8(3.52E-5)
electron transportGO:0006118444.44%0.48%5.39E-8(8.71E-5)
cellular carbohydrate metabolismGO:0044262666.67%3.08%6.19E-8(1E-4)
carbohydrate metabolismGO:0005975666.67%3.38%1.07E-7(1.73E-4)
oxidative phosphorylationGO:0006119444.44%0.71%2.77E-7(4.48E-4)
succinyl-CoA metabolismGO:0006104222.22%0.03%1.73E-6(2.79E-3)
cellular catabolismGO:0044248666.67%5.84%2.76E-6(4.45E-3)
catabolismGO:0009056666.67%6.16%3.79E-6(6.13E-3)
phosphorylationGO:0016310444.44%2.21%2.67E-5(0.04)
phosphate metabolismGO:0006796444.44%2.91%7.83E-5(0.13)
phosphorus metabolismGO:0006793444.44%2.91%7.83E-5(0.13)
tricarboxylic acid cycle intermediate metabolismGO:0006100222.22%0.29%2.92E-4(0.47)
cellular macromolecule metabolismGO:0044260666.67%24.52%8.99E-3(n.s)
macromolecule metabolismGO:0043170666.67%26.04%0.01(n.s)
transportGO:0006810444.44%14.27%0.03(n.s)
establishment of localizationGO:0051234444.44%14.39%0.03(n.s)
localizationGO:0051179444.44%14.82%0.03(n.s)
cellular metabolismGO:0044237777.78%52.12%0.11(n.s)
metabolismGO:0008152777.78%52.93%0.12(n.s)
primary metabolismGO:0044238666.67%48.71%0.23(n.s)
cellular physiological processGO:0050875777.78%71.65%0.51(n.s)
cellular processGO:0009987777.78%72.29%0.53(n.s)
physiological processGO:0007582777.78%73.68%0.56(n.s)
biological process unknownGO:0000004222.22%25.64%0.71(n.s)
biological_processGO:00081509100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptorGO:0016635555.56%0.08%1.35E-15(2.18E-12)
succinate dehydrogenase (ubiquinone) activityGO:0008177555.56%0.08%1.35E-15(2.18E-12)
oxidoreductase activity, acting on the CH-CH group of donorsGO:0016627555.56%0.29%1.56E-11(2.52E-8)
succinate-CoA ligase (ADP-forming) activityGO:0004775222.22%0.03%1.73E-6(2.79E-3)
succinate-CoA ligase activityGO:0004774222.22%0.03%1.73E-6(2.79E-3)
oxidoreductase activityGO:0016491555.56%3.73%7.75E-6(0.01)
acid-thiol ligase activityGO:0016878222.22%0.06%1.04E-5(0.02)
CoA-ligase activityGO:0016405222.22%0.06%1.04E-5(0.02)
ligase activity, forming carbon-sulfur bondsGO:0016877222.22%0.14%6.19E-5(0.1)
catalytic activityGO:0003824777.78%29.21%3.61E-3(n.s)
ligase activityGO:0016874222.22%1.89%0.01(n.s)
molecular function unknownGO:0005554222.22%35.75%0.89(n.s)
molecular_functionGO:00036749100%99.44%0.95(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
succinate dehydrogenase complex (ubiquinone)GO:0045257444.44%0.06%1.74E-12(2.82E-9)
respiratory chain complex II (sensu Eukaryota)GO:0005749444.44%0.06%1.74E-12(2.82E-9)
respiratory chain complex IIGO:0045273444.44%0.06%1.74E-12(2.82E-9)
succinate dehydrogenase complexGO:0045281444.44%0.06%1.74E-12(2.82E-9)
fumarate reductase complexGO:0045283444.44%0.06%1.74E-12(2.82E-9)
mitochondrial electron transport chainGO:0005746444.44%0.4%2.57E-8(4.15E-5)
mitochondrial inner membraneGO:0005743555.56%2.43%9.3E-7(1.5E-3)
inner membraneGO:0019866555.56%2.43%9.3E-7(1.5E-3)
mitochondrionGO:0005739888.89%15.78%2.92E-6(4.71E-3)
mitochondrial membraneGO:0005740555.56%3.16%3.41E-6(5.51E-3)
organelle membraneGO:0031090555.56%8.58%4.3E-4(0.69)
membraneGO:0016020555.56%15.38%6.25E-3(n.s)
nucleoidGO:0009295111.11%0.36%0.03(n.s)
mitochondrial nucleoidGO:0042645111.11%0.36%0.03(n.s)
cytoplasmGO:0005737888.89%55.64%0.04(n.s)
intracellular membrane-bound organelleGO:0043231888.89%55.65%0.04(n.s)
membrane-bound organelleGO:0043227888.89%55.65%0.04(n.s)
organelleGO:0043226888.89%60.56%0.08(n.s)
intracellular organelleGO:0043229888.89%60.56%0.08(n.s)
protein complexGO:0043234444.44%21.07%0.1(n.s)
mitochondrial matrixGO:0005759111.11%2.52%0.21(n.s)
intracellularGO:0005622888.89%77.03%0.35(n.s)
cellGO:0005623888.89%83.5%0.55(n.s)
cellular component unknownGO:0008372111.11%15.74%0.79(n.s)
cellular_componentGO:00055759100%99.61%0.97(n.s)

 

 

cluster_149 (n = 6)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tricarboxylic acid cycle intermediate metabolismGO:0006100583.33%0.29%7.46E-13(1.21E-9)
isocitrate metabolismGO:0006102466.67%0.08%1.04E-12(1.68E-9)
glutamate biosynthesisGO:0006537466.67%0.2%1.48E-10(2.39E-7)
glutamate metabolismGO:0006536466.67%0.25%3.76E-10(6.08E-7)
main pathways of carbohydrate metabolismGO:0006092583.33%1.08%7.72E-10(1.25E-6)
glutamine family amino acid biosynthesisGO:0009084466.67%0.37%2.19E-9(3.54E-6)
glutamine family amino acid metabolismGO:0009064466.67%0.67%2.54E-8(4.1E-5)
energy derivation by oxidation of organic compoundsGO:0015980583.33%3.04%1.44E-7(2.32E-4)
cellular carbohydrate metabolismGO:0044262583.33%3.08%1.55E-7(2.5E-4)
tricarboxylic acid cycleGO:0006099350%0.23%2.02E-7(3.27E-4)
acetyl-CoA catabolismGO:0046356350%0.23%2.02E-7(3.27E-4)
carbohydrate metabolismGO:0005975583.33%3.38%2.45E-7(3.96E-4)
generation of precursor metabolites and energyGO:0006091583.33%3.5%2.94E-7(4.74E-4)
coenzyme catabolismGO:0009109350%0.26%3.02E-7(4.88E-4)
cofactor catabolismGO:0051187350%0.28%3.62E-7(5.85E-4)
acetyl-CoA metabolismGO:0006084350%0.31%5.06E-7(8.17E-4)
amino acid biosynthesisGO:0008652466.67%1.53%7.63E-7(1.23E-3)
amine biosynthesisGO:0009309466.67%1.67%1.08E-6(1.75E-3)
nitrogen compound biosynthesisGO:0044271466.67%1.67%1.08E-6(1.75E-3)
organic acid metabolismGO:0006082583.33%4.6%1.15E-6(1.86E-3)
carboxylic acid metabolismGO:0019752583.33%4.6%1.15E-6(1.86E-3)
coenzyme metabolismGO:0006732466.67%1.81%1.49E-6(2.42E-3)
cofactor metabolismGO:0051186466.67%2.26%3.64E-6(5.88E-3)
amino acid metabolismGO:0006520466.67%2.82%8.77E-6(0.01)
amino acid and derivative metabolismGO:0006519466.67%3.05%1.2E-5(0.02)
amine metabolismGO:0009308466.67%3.38%1.8E-5(0.03)
nitrogen compound metabolismGO:0006807466.67%3.66%2.47E-5(0.04)
aerobic respirationGO:0009060350%1.27%3.84E-5(0.06)
cellular respirationGO:0045333350%1.35%4.59E-5(0.07)
cellular catabolismGO:0044248350%5.84%3.46E-3(n.s)
citrate metabolismGO:0006101116.67%0.06%3.71E-3(n.s)
catabolismGO:0009056350%6.16%4.04E-3(n.s)
cellular macromolecule metabolismGO:0044260583.33%24.52%4.21E-3(n.s)
propionate metabolismGO:0019541116.67%0.08%4.64E-3(n.s)
macromolecule metabolismGO:0043170583.33%26.04%5.6E-3(n.s)
fatty acid beta-oxidationGO:0006635116.67%0.14%8.34E-3(n.s)
cellular biosynthesisGO:0044249466.67%17.05%9.44E-3(n.s)
fatty acid oxidationGO:0019395116.67%0.17%0.01(n.s)
NADPH regenerationGO:0006740116.67%0.17%0.01(n.s)
NADP metabolismGO:0006739116.67%0.19%0.01(n.s)
biosynthesisGO:0009058466.67%18.28%0.01(n.s)
mitochondrial genome maintenanceGO:0000002116.67%0.42%0.02(n.s)
nicotinamide metabolismGO:0006769116.67%0.46%0.03(n.s)
pyridine nucleotide metabolismGO:0019362116.67%0.51%0.03(n.s)
fatty acid metabolismGO:0006631116.67%0.67%0.04(n.s)
oxidoreduction coenzyme metabolismGO:0006733116.67%0.67%0.04(n.s)
vitamin metabolismGO:0006766116.67%1.13%0.07(n.s)
water-soluble vitamin metabolismGO:0006767116.67%1.13%0.07(n.s)
nucleotide metabolismGO:0009117116.67%1.38%0.08(n.s)
mitochondrion organization and biogenesisGO:0007005116.67%1.47%0.09(n.s)
primary metabolismGO:0044238583.33%48.71%0.1(n.s)
cellular metabolismGO:0044237583.33%52.12%0.13(n.s)
metabolismGO:0008152583.33%52.93%0.14(n.s)
cellular lipid metabolismGO:0044255116.67%3.16%0.18(n.s)
lipid metabolismGO:0006629116.67%3.38%0.19(n.s)
cellular physiological processGO:0050875583.33%71.65%0.46(n.s)
cellular processGO:0009987583.33%72.29%0.47(n.s)
physiological processGO:0007582583.33%73.68%0.5(n.s)
organelle organization and biogenesisGO:0006996116.67%15.69%0.64(n.s)
cell organization and biogenesisGO:0016043116.67%17.98%0.7(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139116.67%23.17%0.79(n.s)
biological process unknownGO:0000004116.67%25.64%0.83(n.s)
biological_processGO:00081506100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
isocitrate dehydrogenase activityGO:0004448466.67%0.08%1.04E-12(1.68E-9)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616466.67%1.07%1.76E-7(2.85E-4)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614466.67%1.18%2.61E-7(4.22E-4)
isocitrate dehydrogenase (NAD+) activityGO:0004449233.33%0.03%7.2E-7(1.16E-3)
aconitate hydratase activityGO:0003994233.33%0.03%7.2E-7(1.16E-3)
isocitrate dehydrogenase (NADP+) activityGO:0004450233.33%0.05%2.16E-6(3.49E-3)
oxidoreductase activityGO:0016491466.67%3.73%2.68E-5(0.04)
hydro-lyase activityGO:0016836233.33%0.43%2.69E-4(0.44)
carbon-oxygen lyase activityGO:0016835233.33%0.56%4.47E-4(0.72)
catalytic activityGO:00038246100%29.21%6.18E-4(1)
lyase activityGO:0016829233.33%1.27%2.31E-3(n.s)
molecular_functionGO:00036746100%99.44%0.97(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nucleoidGO:0009295350%0.36%7.85E-7(1.27E-3)
mitochondrial nucleoidGO:0042645350%0.36%7.85E-7(1.27E-3)
mitochondrial matrixGO:0005759466.67%2.52%5.65E-6(9.13E-3)
mitochondrionGO:00057396100%15.78%1.53E-5(0.02)
cytoplasmGO:00057376100%55.64%0.03(n.s)
intracellular membrane-bound organelleGO:00432316100%55.65%0.03(n.s)
membrane-bound organelleGO:00432276100%55.65%0.03(n.s)
organelleGO:00432266100%60.56%0.05(n.s)
intracellular organelleGO:00432296100%60.56%0.05(n.s)
peroxisomeGO:0005777116.67%0.87%0.05(n.s)
microbodyGO:0042579116.67%0.87%0.05(n.s)
intracellularGO:00056226100%77.03%0.21(n.s)
cellGO:00056236100%83.5%0.34(n.s)
cytosolGO:0005829116.67%10.08%0.47(n.s)
cellular_componentGO:00055756100%99.61%0.98(n.s)

 

 

cluster_79 (n = 48)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein biosynthesisGO:00064124491.67%12.16%2.22E-36(3.59E-33)
macromolecule biosynthesisGO:00090594491.67%13.04%5.08E-35(8.22E-32)
cellular biosynthesisGO:00442494491.67%17.05%7.41E-30(1.2E-26)
biosynthesisGO:00090584491.67%18.28%1.56E-28(2.53E-25)
cellular protein metabolismGO:00442674491.67%21.7%2.88E-25(4.65E-22)
protein metabolismGO:00195384491.67%22.06%5.85E-25(9.45E-22)
cellular macromolecule metabolismGO:00442604491.67%24.52%5.82E-23(9.41E-20)
macromolecule metabolismGO:00431704491.67%26.04%7.84E-22(1.27E-18)
primary metabolismGO:00442384593.75%48.71%1.89E-11(3.06E-8)
cellular metabolismGO:00442374593.75%52.12%3.33E-10(5.38E-7)
metabolismGO:00081524593.75%52.93%6.35E-10(1.03E-6)
cellular physiological processGO:005087548100%71.65%1.05E-7(1.7E-4)
cellular processGO:000998748100%72.29%1.61E-7(2.6E-4)
physiological processGO:000758248100%73.68%4.04E-7(6.53E-4)
aerobic respirationGO:0009060510.42%1.27%3.26E-4(0.53)
cellular respirationGO:0045333510.42%1.35%4.3E-4(0.69)
mitochondrial genome maintenanceGO:000000236.25%0.42%9.95E-4(n.s)
ribosomal large subunit assembly and maintenanceGO:000002736.25%0.6%2.92E-3(n.s)
ribosomal subunit assemblyGO:004225736.25%0.81%6.6E-3(n.s)
ribosome assemblyGO:004225536.25%0.99%0.01(n.s)
energy derivation by oxidation of organic compoundsGO:0015980510.42%3.04%0.01(n.s)
generation of precursor metabolites and energyGO:0006091510.42%3.5%0.03(n.s)
mitochondrion organization and biogenesisGO:000700536.25%1.47%0.03(n.s)
protein complex assemblyGO:000646136.25%2.26%0.09(n.s)
cytoplasm organization and biogenesisGO:000702848.33%3.9%0.12(n.s)
ribosome biogenesis and assemblyGO:004225448.33%3.9%0.12(n.s)
axial bud site selectionGO:000712012.08%0.34%0.15(n.s)
sterol metabolismGO:001612512.08%0.57%0.24(n.s)
fatty acid metabolismGO:000663112.08%0.67%0.28(n.s)
steroid metabolismGO:000820212.08%0.7%0.29(n.s)
bud site selectionGO:000028212.08%1.01%0.39(n.s)
cytokinesis, site selectionGO:000710512.08%1.01%0.39(n.s)
cell buddingGO:000711412.08%1.19%0.44(n.s)
asexual reproductionGO:001995412.08%1.19%0.44(n.s)
cellular lipid metabolismGO:004425524.17%3.16%0.45(n.s)
lipid metabolismGO:000662924.17%3.38%0.49(n.s)
organelle organization and biogenesisGO:0006996816.67%15.69%0.49(n.s)
cytokinesisGO:000091012.08%1.5%0.52(n.s)
establishment of cell polarity (sensu Fungi)GO:003046812.08%1.6%0.54(n.s)
establishment of cell polarityGO:003001012.08%1.6%0.54(n.s)
establishment and/or maintenance of cell polarity (sensu Fungi)GO:003046712.08%1.66%0.55(n.s)
establishment and/or maintenance of cell polarityGO:000716312.08%1.66%0.55(n.s)
cell divisionGO:005130112.08%1.91%0.6(n.s)
cell organization and biogenesisGO:0016043816.67%17.98%0.65(n.s)
cellular morphogenesisGO:000090212.08%2.23%0.66(n.s)
morphogenesisGO:000965312.08%2.23%0.66(n.s)
alcohol metabolismGO:000606612.08%2.43%0.69(n.s)
ribosome biogenesisGO:000704612.08%3.3%0.8(n.s)
reproductionGO:000000312.08%3.92%0.85(n.s)
cytoskeleton organization and biogenesisGO:000701012.08%4.48%0.89(n.s)
organic acid metabolismGO:000608212.08%4.6%0.9(n.s)
carboxylic acid metabolismGO:001975212.08%4.6%0.9(n.s)
developmentGO:000727512.08%5.73%0.94(n.s)
translationGO:004303712.08%6.47%0.96(n.s)
biological_processGO:000815048100%99.98%0.99(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
structural constituent of ribosomeGO:00037354491.67%3.58%5.77E-61(9.32E-58)
structural molecule activityGO:00051984491.67%5.51%4.89E-52(7.9E-49)
peptidyltransferase activityGO:000004836.25%0.05%3.86E-7(6.24E-4)
transferase activity, transferring amino-acyl groupsGO:001675536.25%0.08%3.82E-6(6.17E-3)
sterol 3-beta-glucosyltransferase activityGO:001690612.08%0.02%**
transferase activity, transferring acyl groupsGO:001674636.25%1.43%0.03(n.s)
UDP-glucosyltransferase activityGO:003525112.08%0.19%0.09(n.s)
glucosyltransferase activityGO:004652712.08%0.22%0.1(n.s)
UDP-glycosyltransferase activityGO:000819412.08%0.26%0.12(n.s)
RNA helicase activityGO:000372412.08%0.64%0.26(n.s)
transferase activity, transferring hexosyl groupsGO:001675812.08%1.12%0.42(n.s)
helicase activityGO:000438612.08%1.3%0.47(n.s)
transferase activity, transferring glycosyl groupsGO:001675712.08%1.41%0.5(n.s)
transferase activityGO:001674048.33%10.13%0.73(n.s)
molecular_functionGO:000367448100%99.44%0.76(n.s)
transcription regulator activityGO:003052812.08%5%0.92(n.s)
catalytic activityGO:0003824510.42%29.21%1(n.s)
molecular function unknownGO:000555424.17%35.75%1(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial large ribosomal subunitGO:00057624389.58%0.68%7.77E-104(1.26E-100)
organellar large ribosomal subunitGO:00003154389.58%0.68%7.77E-104(1.26E-100)
organellar ribosomeGO:00003134491.67%1.29%9.79E-85(1.58E-81)
mitochondrial ribosomeGO:00057614491.67%1.29%9.79E-85(1.58E-81)
large ribosomal subunitGO:00159344389.58%2.12%1.25E-69(2.03E-66)
mitochondrial matrixGO:00057594491.67%2.52%1.73E-68(2.8E-65)
ribosomeGO:00058404491.67%4.4%1.17E-56(1.89E-53)
ribonucleoprotein complexGO:00305294491.67%7.19%1.03E-46(1.66E-43)
intracellular non-membrane-bound organelleGO:00432324593.75%14.3%4.26E-35(6.89E-32)
non-membrane-bound organelleGO:00432284593.75%14.3%4.26E-35(6.89E-32)
mitochondrionGO:00057394695.83%15.78%4.49E-35(7.26E-32)
protein complexGO:00432344491.67%21.07%7.87E-26(1.27E-22)
cytoplasmGO:000573748100%55.64%5.21E-13(8.42E-10)
intracellular membrane-bound organelleGO:00432314695.83%55.65%4.09E-10(6.61E-7)
membrane-bound organelleGO:00432274695.83%55.65%4.09E-10(6.61E-7)
organelleGO:00432264797.92%60.56%1.02E-9(1.65E-6)
intracellular organelleGO:00432294797.92%60.56%1.02E-9(1.65E-6)
intracellularGO:000562248100%77.03%3.44E-6(5.56E-3)
cellGO:000562348100%83.5%1.69E-4(0.27)
contractile ringGO:000582612.08%0.33%0.15(n.s)
contractile ring (sensu Fungi)GO:003048012.08%0.33%0.15(n.s)
contractile ring (sensu Saccharomyces)GO:000014212.08%0.33%0.15(n.s)
actin cytoskeletonGO:001562912.08%1.38%0.49(n.s)
cell cortexGO:000593812.08%1.52%0.52(n.s)
bud neckGO:000593512.08%1.64%0.55(n.s)
budGO:000593312.08%2.12%0.64(n.s)
site of polarized growthGO:003042712.08%2.21%0.66(n.s)
cytoskeletonGO:000585612.08%2.93%0.76(n.s)
cellular_componentGO:000557548100%99.61%0.83(n.s)
nucleusGO:000563412.08%31.01%1(n.s)

 

 

cluster_133 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrion organization and biogenesisGO:00070052100%1.47%2.14E-4(0.35)
loss of chromatin silencing during replicative cell agingGO:0001308150%0.12%2.48E-3(n.s)
loss of chromatin silencingGO:0006345150%0.14%2.79E-3(n.s)
positive regulation of gene expression, epigeneticGO:0045815150%0.14%2.79E-3(n.s)
progressive alteration of chromatin during replicative cell agingGO:0001304150%0.14%2.79E-3(n.s)
progressive alteration of chromatin during cell agingGO:0001301150%0.15%3.1E-3(n.s)
replicative cell agingGO:0001302150%0.51%0.01(n.s)
cell agingGO:0007569150%0.64%0.01(n.s)
agingGO:0007568150%0.65%0.01(n.s)
cell deathGO:0008219150%0.71%0.01(n.s)
deathGO:0016265150%0.73%0.01(n.s)
positive regulation of transcription, DNA-dependentGO:0045893150%0.91%0.02(n.s)
positive regulation of transcriptionGO:0045941150%1.01%0.02(n.s)
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045935150%1.02%0.02(n.s)
positive regulation of cellular metabolismGO:0031325150%1.05%0.02(n.s)
positive regulation of metabolismGO:0009893150%1.05%0.02(n.s)
positive regulation of cellular processGO:0048522150%1.1%0.02(n.s)
positive regulation of cellular physiological processGO:0051242150%1.1%0.02(n.s)
positive regulation of physiological processGO:0043119150%1.1%0.02(n.s)
positive regulation of biological processGO:0048518150%1.21%0.02(n.s)
organelle organization and biogenesisGO:00069962100%15.69%0.02(n.s)
regulation of gene expression, epigeneticGO:0040029150%1.27%0.03(n.s)
cell organization and biogenesisGO:00160432100%17.98%0.03(n.s)
chromatin remodelingGO:0006338150%2.01%0.04(n.s)
chromatin modificationGO:0016568150%2.77%0.05(n.s)
DNA packagingGO:0006323150%3.14%0.06(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325150%3.14%0.06(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001150%3.72%0.07(n.s)
chromosome organization and biogenesisGO:0051276150%3.9%0.08(n.s)
regulation of transcription, DNA-dependentGO:0006355150%4.68%0.09(n.s)
regulation of transcriptionGO:0045449150%4.96%0.1(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219150%5.24%0.1(n.s)
developmentGO:0007275150%5.73%0.11(n.s)
regulation of cellular metabolismGO:0031323150%5.98%0.12(n.s)
regulation of metabolismGO:0019222150%6.37%0.12(n.s)
transcription, DNA-dependentGO:0006351150%6.78%0.13(n.s)
transcriptionGO:0006350150%7.43%0.14(n.s)
regulation of cellular physiological processGO:0051244150%8.49%0.16(n.s)
regulation of cellular processGO:0050794150%8.52%0.16(n.s)
DNA metabolismGO:0006259150%8.58%0.16(n.s)
regulation of physiological processGO:0050791150%8.77%0.17(n.s)
regulation of biological processGO:0050789150%8.97%0.17(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glucosidase activityGO:0015926150%0.42%8.35E-3(n.s)
hydrolase activity, hydrolyzing O-glycosyl compoundsGO:0004553150%0.82%0.02(n.s)
hydrolase activity, acting on glycosyl bondsGO:0016798150%0.93%0.02(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cell wall (sensu Fungi)GO:00092772100%1.72%2.93E-4(0.47)
external encapsulating structureGO:00303122100%1.72%2.93E-4(0.47)
cell wallGO:00056182100%1.72%2.93E-4(0.47)
mitochondrial outer membraneGO:0005741150%0.53%0.01(n.s)
outer membraneGO:0019867150%0.53%0.01(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial matrixGO:0005759150%2.52%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_131 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial protein processingGO:0006627266.67%0.09%2.16E-6(3.49E-3)
protein processingGO:0016485266.67%0.51%7.58E-5(0.12)
protein-mitochondrial targetingGO:0006626266.67%0.73%1.55E-4(0.25)
protein targetingGO:0006605266.67%3.42%3.42E-3(n.s)
intracellular protein transportGO:0006886266.67%3.7%3.99E-3(n.s)
protein transportGO:0015031266.67%3.79%4.2E-3(n.s)
establishment of protein localizationGO:0045184266.67%3.95%4.54E-3(n.s)
protein localizationGO:0008104266.67%4.37%5.54E-3(n.s)
protein modificationGO:0006464266.67%6.68%0.01(n.s)
biopolymer metabolismGO:00432833100%25.06%0.02(n.s)
intracellular transportGO:0046907266.67%7.53%0.02(n.s)
macromolecule metabolismGO:00431703100%26.04%0.02(n.s)
biopolymer modificationGO:0043412266.67%9.25%0.02(n.s)
mRNA catabolismGO:0006402133.33%0.85%0.03(n.s)
RNA catabolismGO:0006401133.33%0.99%0.03(n.s)
35S primary transcript processingGO:0006365133.33%1.04%0.03(n.s)
transportGO:0006810266.67%14.27%0.06(n.s)
establishment of localizationGO:0051234266.67%14.39%0.06(n.s)
localizationGO:0051179266.67%14.82%0.06(n.s)
rRNA processingGO:0006364133.33%2.71%0.08(n.s)
mRNA metabolismGO:0016071133.33%2.85%0.08(n.s)
ribosome biogenesisGO:0007046133.33%3.3%0.1(n.s)
cytoplasm organization and biogenesisGO:0007028133.33%3.9%0.11(n.s)
ribosome biogenesis and assemblyGO:0042254133.33%3.9%0.11(n.s)
rRNA metabolismGO:0016072133.33%3.92%0.11(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular protein metabolismGO:0044267266.67%21.7%0.12(n.s)
protein metabolismGO:0019538266.67%22.06%0.12(n.s)
cellular macromolecule catabolismGO:0044265133.33%4.51%0.13(n.s)
macromolecule catabolismGO:0009057133.33%4.83%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular macromolecule metabolismGO:0044260266.67%24.52%0.15(n.s)
RNA processingGO:0006396133.33%5.33%0.15(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
RNA metabolismGO:0016070133.33%8.32%0.23(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
organelle organization and biogenesisGO:0006996133.33%15.69%0.4(n.s)
cell organization and biogenesisGO:0016043133.33%17.98%0.45(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139133.33%23.17%0.55(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial processing peptidase activityGO:0004240266.67%0.03%1.44E-7(2.33E-4)
metalloendopeptidase activityGO:0004222266.67%0.31%2.73E-5(0.04)
metallopeptidase activityGO:0008237266.67%0.43%5.43E-5(0.09)
endopeptidase activityGO:0004175266.67%0.99%2.88E-4(0.47)
hydrolase activityGO:00167873100%11.45%1.49E-3(n.s)
peptidase activityGO:0008233266.67%2.48%1.8E-3(n.s)
3'-5'-exoribonuclease activityGO:0000175133.33%0.28%8.34E-3(n.s)
exoribonuclease activityGO:0004532133.33%0.36%0.01(n.s)
exoribonuclease activity, producing 5'-phosphomonoestersGO:0016896133.33%0.36%0.01(n.s)
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersGO:0016796133.33%0.37%0.01(n.s)
3'-5' exonuclease activityGO:0008408133.33%0.39%0.01(n.s)
exonuclease activityGO:0004527133.33%0.51%0.02(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
ribonuclease activityGO:0004540133.33%1.55%0.05(n.s)
nuclease activityGO:0004518133.33%2.15%0.06(n.s)
hydrolase activity, acting on ester bondsGO:0016788133.33%4.12%0.12(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial processing peptidase complexGO:0017087266.67%0.03%1.44E-7(2.33E-4)
mitochondrial matrixGO:0005759266.67%2.52%1.87E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmic exosome (RNase complex)GO:0000177133.33%0.15%4.64E-3(n.s)
nuclear exosome (RNase complex)GO:0000176133.33%0.19%5.57E-3(n.s)
exosome (RNase complex)GO:0000178133.33%0.2%6.03E-3(n.s)
protein complexGO:00432343100%21.07%9.33E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
nucleusGO:0005634133.33%31.01%0.67(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_130 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein biosynthesisGO:00064122100%12.16%0.01(n.s)
macromolecule biosynthesisGO:00090592100%13.04%0.02(n.s)
cellular biosynthesisGO:00442492100%17.05%0.03(n.s)
biosynthesisGO:00090582100%18.28%0.03(n.s)
cellular protein metabolismGO:00442672100%21.7%0.05(n.s)
protein metabolismGO:00195382100%22.06%0.05(n.s)
cellular macromolecule metabolismGO:00442602100%24.52%0.06(n.s)
macromolecule metabolismGO:00431702100%26.04%0.07(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
aminoacyl-tRNA hydrolase activityGO:00040452100%0.03%4.8E-8(7.76E-5)
carboxylic ester hydrolase activityGO:00167892100%0.46%2.09E-5(0.03)
hydrolase activity, acting on ester bondsGO:00167882100%4.12%1.69E-3(n.s)
hydrolase activityGO:00167872100%11.45%0.01(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_137 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
proteolysis and peptidolysisGO:0006508150%2.42%0.05(n.s)
cellular protein catabolismGO:0044257150%2.42%0.05(n.s)
protein catabolismGO:0030163150%2.74%0.05(n.s)
biopolymer catabolismGO:0043285150%2.93%0.06(n.s)
cellular macromolecule catabolismGO:0044265150%4.51%0.09(n.s)
macromolecule catabolismGO:0009057150%4.83%0.09(n.s)
cellular catabolismGO:0044248150%5.84%0.11(n.s)
catabolismGO:0009056150%6.16%0.12(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membrane peptidase complexGO:0042720150%0.05%9.29E-4(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
protein complexGO:0043234150%21.07%0.38(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_136 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
base-excision repairGO:00062844100%0.15%2.9E-12(4.69E-9)
base-excision repair, AP site formationGO:0006285375%0.05%8.92E-11(1.44E-7)
DNA repairGO:00062814100%2.32%2.8E-7(4.53E-4)
response to DNA damage stimulusGO:00069744100%2.73%5.34E-7(8.63E-4)
response to endogenous stimulusGO:00097194100%2.82%6.12E-7(9.88E-4)
response to stressGO:00069504100%6.09%1.35E-5(0.02)
response to stimulusGO:00508964100%8.41%4.95E-5(0.08)
DNA metabolismGO:00062594100%8.58%5.37E-5(0.09)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061394100%23.17%2.87E-3(n.s)
biopolymer metabolismGO:00432834100%25.06%3.93E-3(n.s)
primary metabolismGO:00442384100%48.71%0.06(n.s)
cellular metabolismGO:00442374100%52.12%0.07(n.s)
metabolismGO:00081524100%52.93%0.08(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA-(apurinic or apyrimidinic site) lyase activityGO:00039064100%0.06%1.38E-14(2.23E-11)
oxidized base lesion DNA N-glycosylase activityGO:0000702375%0.05%8.92E-11(1.44E-7)
carbon-oxygen lyase activityGO:00168354100%0.56%8.15E-10(1.32E-6)
DNA N-glycosylase activityGO:0019104375%0.09%1.78E-9(2.88E-6)
hydrolase activity, hydrolyzing N-glycosyl compoundsGO:0016799375%0.11%3.12E-9(5.04E-6)
lyase activityGO:00168294100%1.27%2.42E-8(3.91E-5)
endodeoxyribonuclease activityGO:0004520375%0.28%7.27E-8(1.17E-4)
deoxyribonuclease activityGO:0004536375%0.31%1.02E-7(1.64E-4)
purine-specific oxidized base lesion DNA N-glycosylase activityGO:0008534250%0.03%2.88E-7(4.65E-4)
pyrimidine-specific oxidized base lesion DNA N-glycosylase activityGO:0000703250%0.03%2.88E-7(4.65E-4)
endonuclease activityGO:0004519375%0.88%2.59E-6(4.19E-3)
hydrolase activity, acting on glycosyl bondsGO:0016798375%0.93%3.03E-6(4.9E-3)
nuclease activityGO:0004518375%2.15%3.85E-5(0.06)
hydrolase activity, acting on ester bondsGO:0016788375%4.12%2.68E-4(0.43)
hydrolase activityGO:0016787375%11.45%5.47E-3(n.s)
catalytic activityGO:00038244100%29.21%7.27E-3(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739375%15.78%0.01(n.s)
nucleusGO:0005634375%31.01%0.09(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cytoplasmGO:0005737375%55.64%0.4(n.s)
cellGO:00056234100%83.5%0.49(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_135 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nucleoside catabolismGO:0009164150%0.06%1.24E-3(n.s)
nucleoside metabolismGO:0009116150%0.22%4.33E-3(n.s)
cellular catabolismGO:0044248150%5.84%0.11(n.s)
catabolismGO:0009056150%6.16%0.12(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nucleoside-triphosphatase activityGO:0017111150%3.42%0.07(n.s)
pyrophosphatase activityGO:0016462150%3.67%0.07(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818150%3.69%0.07(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817150%3.69%0.07(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cellular component unknownGO:0008372150%15.74%0.29(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
intracellularGO:0005622150%77.03%0.95(n.s)
cellGO:0005623150%83.5%0.97(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_134 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
anaerobic respirationGO:0009061266.67%0.05%4.32E-7(6.98E-4)
cellular respirationGO:00453333100%1.35%2.36E-6(3.82E-3)
mitochondrial transportGO:0006839266.67%0.17%7.91E-6(0.01)
energy derivation by oxidation of organic compoundsGO:00159803100%3.04%2.76E-5(0.04)
generation of precursor metabolites and energyGO:00060913100%3.5%4.23E-5(0.07)
aerobic respirationGO:0009060266.67%1.27%4.74E-4(0.77)
intracellular transportGO:0046907266.67%7.53%0.02(n.s)
transportGO:0006810266.67%14.27%0.06(n.s)
establishment of localizationGO:0051234266.67%14.39%0.06(n.s)
localizationGO:0051179266.67%14.82%0.06(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ATP:ADP antiporter activityGO:00054713100%0.05%2.23E-11(3.6E-8)
solute:solute antiporter activityGO:00153003100%0.08%2.23E-10(3.6E-7)
antiporter activityGO:00152973100%0.14%1.87E-9(3.03E-6)
porter activityGO:00152913100%0.59%1.88E-7(3.04E-4)
electrochemical potential-driven transporter activityGO:00152903100%0.59%1.88E-7(3.04E-4)
carrier activityGO:00053863100%1.64%4.3E-6(6.95E-3)
transporter activityGO:00052153100%6.64%2.92E-4(0.47)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:00057433100%2.43%1.41E-5(0.02)
inner membraneGO:00198663100%2.43%1.41E-5(0.02)
mitochondrial membraneGO:00057403100%3.16%3.11E-5(0.05)
organelle membraneGO:00310903100%8.58%6.29E-4(n.s)
membraneGO:00160203100%15.38%3.63E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_139 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
proteolysis and peptidolysisGO:0006508133.33%2.42%0.07(n.s)
cellular protein catabolismGO:0044257133.33%2.42%0.07(n.s)
protein catabolismGO:0030163133.33%2.74%0.08(n.s)
biopolymer catabolismGO:0043285133.33%2.93%0.09(n.s)
cellular macromolecule catabolismGO:0044265133.33%4.51%0.13(n.s)
macromolecule catabolismGO:0009057133.33%4.83%0.14(n.s)
biological process unknownGO:0000004266.67%25.64%0.16(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biopolymer metabolismGO:0043283133.33%25.06%0.58(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
cellular physiological processGO:0050875133.33%71.65%0.98(n.s)
cellular processGO:0009987133.33%72.29%0.98(n.s)
physiological processGO:0007582133.33%73.68%0.98(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
metalloendopeptidase activityGO:0004222133.33%0.31%9.27E-3(n.s)
metallopeptidase activityGO:0008237133.33%0.43%0.01(n.s)
endopeptidase activityGO:0004175133.33%0.99%0.03(n.s)
peptidase activityGO:0008233133.33%2.48%0.07(n.s)
molecular function unknownGO:0005554266.67%35.75%0.29(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytoplasmGO:00057373100%55.64%0.17(n.s)
nucleusGO:0005634266.67%31.01%0.23(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_138 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lipoic acid metabolismGO:0000273150%0.02%**
protein-lipoylationGO:0009249150%0.02%**
lipoic acid biosynthesisGO:0009105150%0.02%**
protein-cofactor linkageGO:0018065150%0.06%1.24E-3(n.s)
coenzyme biosynthesisGO:0009108150%0.87%0.02(n.s)
cofactor biosynthesisGO:0051188150%1.08%0.02(n.s)
heterocycle metabolismGO:0046483150%1.1%0.02(n.s)
coenzyme metabolismGO:0006732150%1.81%0.04(n.s)
cofactor metabolismGO:0051186150%2.26%0.04(n.s)
organic acid metabolismGO:0006082150%4.6%0.09(n.s)
carboxylic acid metabolismGO:0019752150%4.6%0.09(n.s)
protein modificationGO:0006464150%6.68%0.13(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lipoic acid synthase activityGO:0017140150%0.02%**
ligase activityGO:0016874150%1.89%0.04(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_25 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein complex assemblyGO:0006461266.67%2.26%1.5E-3(n.s)
cellular protein metabolismGO:0044267266.67%21.7%0.12(n.s)
protein metabolismGO:0019538266.67%22.06%0.12(n.s)
cellular macromolecule metabolismGO:0044260266.67%24.52%0.15(n.s)
macromolecule metabolismGO:0043170266.67%26.04%0.17(n.s)
primary metabolismGO:0044238266.67%48.71%0.48(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055543100%35.75%0.05(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial membraneGO:0005740266.67%3.16%2.92E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
organelle membraneGO:0031090266.67%8.58%0.02(n.s)
membraneGO:0016020266.67%15.38%0.06(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_26 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glycine biosynthesisGO:0006545133.33%0.03%9.29E-4(n.s)
glycine metabolismGO:0006544133.33%0.09%2.79E-3(n.s)
NAD biosynthesisGO:0009435133.33%0.11%3.25E-3(n.s)
pyridine nucleotide biosynthesisGO:0019363133.33%0.12%3.71E-3(n.s)
serine family amino acid biosynthesisGO:0009070133.33%0.19%5.57E-3(n.s)
NAD metabolismGO:0019674133.33%0.22%6.49E-3(n.s)
serine family amino acid metabolismGO:0009069133.33%0.34%0.01(n.s)
nicotinamide metabolismGO:0006769133.33%0.46%0.01(n.s)
pyridine nucleotide metabolismGO:0019362133.33%0.51%0.02(n.s)
vitamin biosynthesisGO:0009110133.33%0.59%0.02(n.s)
water-soluble vitamin biosynthesisGO:0042364133.33%0.59%0.02(n.s)
oxidoreduction coenzyme metabolismGO:0006733133.33%0.67%0.02(n.s)
nucleotide biosynthesisGO:0009165133.33%0.84%0.02(n.s)
coenzyme biosynthesisGO:0009108133.33%0.87%0.03(n.s)
cofactor biosynthesisGO:0051188133.33%1.08%0.03(n.s)
water-soluble vitamin metabolismGO:0006767133.33%1.13%0.03(n.s)
vitamin metabolismGO:0006766133.33%1.13%0.03(n.s)
nucleotide metabolismGO:0009117133.33%1.38%0.04(n.s)
amino acid biosynthesisGO:0008652133.33%1.53%0.05(n.s)
nitrogen compound biosynthesisGO:0044271133.33%1.67%0.05(n.s)
amine biosynthesisGO:0009309133.33%1.67%0.05(n.s)
coenzyme metabolismGO:0006732133.33%1.81%0.05(n.s)
cofactor metabolismGO:0051186133.33%2.26%0.07(n.s)
cellular biosynthesisGO:0044249266.67%17.05%0.08(n.s)
amino acid metabolismGO:0006520133.33%2.82%0.08(n.s)
biosynthesisGO:0009058266.67%18.28%0.09(n.s)
amino acid and derivative metabolismGO:0006519133.33%3.05%0.09(n.s)
amine metabolismGO:0009308133.33%3.38%0.1(n.s)
nitrogen compound metabolismGO:0006807133.33%3.66%0.11(n.s)
organic acid metabolismGO:0006082133.33%4.6%0.13(n.s)
carboxylic acid metabolismGO:0019752133.33%4.6%0.13(n.s)
primary metabolismGO:0044238266.67%48.71%0.48(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139133.33%23.17%0.55(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
arylformamidase activityGO:0004061133.33%0.02%**
alanine-glyoxylate transaminase activityGO:0008453133.33%0.02%**
transferase activity, transferring nitrogenous groupsGO:0016769133.33%0.25%7.42E-3(n.s)
transaminase activityGO:0008483133.33%0.25%7.42E-3(n.s)
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidesGO:0016811133.33%0.56%0.02(n.s)
hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsGO:0016810133.33%0.93%0.03(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
transferase activityGO:0016740133.33%10.13%0.27(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_21 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
methylglyoxal catabolismGO:0019243266.67%0.05%4.32E-7(6.98E-4)
methylglyoxal metabolismGO:0009438266.67%0.05%4.32E-7(6.98E-4)
aldehyde catabolismGO:0046185266.67%0.08%1.44E-6(2.33E-3)
aldehyde metabolismGO:0006081266.67%0.29%2.46E-5(0.04)
carbohydrate metabolismGO:00059753100%3.38%3.8E-5(0.06)
cellular catabolismGO:00442483100%5.84%1.98E-4(0.32)
catabolismGO:00090563100%6.16%2.33E-4(0.38)
glycolysisGO:0006096133.33%0.34%0.01(n.s)
gluconeogenesisGO:0006094133.33%0.4%0.01(n.s)
monosaccharide biosynthesisGO:0046364133.33%0.43%0.01(n.s)
hexose biosynthesisGO:0019319133.33%0.43%0.01(n.s)
glucose catabolismGO:0006007133.33%0.45%0.01(n.s)
hexose catabolismGO:0019320133.33%0.45%0.01(n.s)
alcohol biosynthesisGO:0046165133.33%0.46%0.01(n.s)
monosaccharide catabolismGO:0046365133.33%0.53%0.02(n.s)
alcohol catabolismGO:0046164133.33%0.57%0.02(n.s)
pyruvate metabolismGO:0006090133.33%0.57%0.02(n.s)
macromolecule metabolismGO:00431703100%26.04%0.02(n.s)
carbohydrate biosynthesisGO:0016051133.33%0.91%0.03(n.s)
glucose metabolismGO:0006006133.33%1.01%0.03(n.s)
main pathways of carbohydrate metabolismGO:0006092133.33%1.08%0.03(n.s)
cellular carbohydrate catabolismGO:0044275133.33%1.1%0.03(n.s)
carbohydrate catabolismGO:0016052133.33%1.1%0.03(n.s)
hexose metabolismGO:0019318133.33%1.32%0.04(n.s)
monosaccharide metabolismGO:0005996133.33%1.43%0.04(n.s)
alcohol metabolismGO:0006066133.33%2.43%0.07(n.s)
energy derivation by oxidation of organic compoundsGO:0015980133.33%3.04%0.09(n.s)
cellular carbohydrate metabolismGO:0044262133.33%3.08%0.09(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular macromolecule catabolismGO:0044265133.33%4.51%0.13(n.s)
organic acid metabolismGO:0006082133.33%4.6%0.13(n.s)
carboxylic acid metabolismGO:0019752133.33%4.6%0.13(n.s)
macromolecule catabolismGO:0009057133.33%4.83%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
macromolecule biosynthesisGO:0009059133.33%13.04%0.34(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular biosynthesisGO:0044249133.33%17.05%0.43(n.s)
biosynthesisGO:0009058133.33%18.28%0.45(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydroxyacylglutathione hydrolase activityGO:0004416266.67%0.03%1.44E-7(2.33E-4)
thiolester hydrolase activityGO:0016790266.67%0.08%1.44E-6(2.33E-3)
glyceraldehyde-3-phosphate dehydrogenase activityGO:0008943133.33%0.05%1.39E-3(n.s)
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activityGO:0004365133.33%0.05%1.39E-3(n.s)
hydrolase activity, acting on ester bondsGO:0016788266.67%4.12%4.94E-3(n.s)
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorGO:0016620133.33%0.29%8.8E-3(n.s)
oxidoreductase activity, acting on the aldehyde or oxo group of donorsGO:0016903133.33%0.36%0.01(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
hydrolase activityGO:0016787266.67%11.45%0.04(n.s)
oxidoreductase activityGO:0016491133.33%3.73%0.11(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lipid particleGO:0005811133.33%0.51%0.02(n.s)
cell wall (sensu Fungi)GO:0009277133.33%1.72%0.05(n.s)
external encapsulating structureGO:0030312133.33%1.72%0.05(n.s)
cell wallGO:0005618133.33%1.72%0.05(n.s)
mitochondrial matrixGO:0005759133.33%2.52%0.07(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
mitochondrionGO:0005739133.33%15.78%0.4(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231133.33%55.65%0.91(n.s)
membrane-bound organelleGO:0043227133.33%55.65%0.91(n.s)
organelleGO:0043226133.33%60.56%0.94(n.s)
intracellular organelleGO:0043229133.33%60.56%0.94(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_23 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein deubiquitinationGO:0016579150%0.28%5.57E-3(n.s)
ubiquitin cycleGO:0006512150%1.07%0.02(n.s)
protein modificationGO:0006464150%6.68%0.13(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ubiquitin-specific protease activityGO:0004843150%0.26%5.26E-3(n.s)
cysteine-type peptidase activityGO:0008234150%0.43%8.66E-3(n.s)
peptidase activityGO:0008233150%2.48%0.05(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_160 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
monosaccharide transportGO:00157492100%0.33%1.01E-5(0.02)
hexose transportGO:00086452100%0.33%1.01E-5(0.02)
carbohydrate transportGO:00086432100%0.53%2.69E-5(0.04)
transportGO:00068102100%14.27%0.02(n.s)
establishment of localizationGO:00512342100%14.39%0.02(n.s)
localizationGO:00511792100%14.82%0.02(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
fructose transporter activityGO:00053532100%0.23%5.04E-6(8.14E-3)
mannose transporter activityGO:00155782100%0.23%5.04E-6(8.14E-3)
glucose transporter activityGO:00053552100%0.28%7.34E-6(0.01)
hexose transporter activityGO:00151492100%0.33%1.01E-5(0.02)
monosaccharide transporter activityGO:00151452100%0.33%1.01E-5(0.02)
sugar transporter activityGO:00511192100%0.43%1.81E-5(0.03)
carbohydrate transporter activityGO:00151442100%0.51%2.53E-5(0.04)
transporter activityGO:00052152100%6.64%4.41E-3(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
plasma membraneGO:00058862100%3.67%1.34E-3(n.s)
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_29 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
peptide metabolismGO:0006518150%0.12%2.48E-3(n.s)
response to heatGO:0009408150%0.26%5.26E-3(n.s)
response to temperatureGO:0009266150%0.31%6.19E-3(n.s)
response to abiotic stimulusGO:0009628150%3.52%0.07(n.s)
response to external stimulusGO:0009605150%3.87%0.08(n.s)
response to stressGO:0006950150%6.09%0.12(n.s)
response to stimulusGO:0050896150%8.41%0.16(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
leucyl aminopeptidase activityGO:0004178150%0.02%**
metalloexopeptidase activityGO:0008235150%0.08%1.55E-3(n.s)
protein kinase inhibitor activityGO:0004860150%0.09%1.86E-3(n.s)
kinase inhibitor activityGO:0019210150%0.11%2.17E-3(n.s)
aminopeptidase activityGO:0004177150%0.17%3.41E-3(n.s)
exopeptidase activityGO:0008238150%0.25%4.95E-3(n.s)
enzyme inhibitor activityGO:0004857150%0.34%6.8E-3(n.s)
metallopeptidase activityGO:0008237150%0.43%8.66E-3(n.s)
protein kinase regulator activityGO:0019887150%0.56%0.01(n.s)
kinase regulator activityGO:0019207150%0.6%0.01(n.s)
peptidase activityGO:0008233150%2.48%0.05(n.s)
enzyme regulator activityGO:0030234150%2.54%0.05(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
periplasmic spaceGO:0042597150%0.12%2.48E-3(n.s)
periplasmic space (sensu Fungi)GO:0030287150%0.12%2.48E-3(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_161 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mRNA-nucleus exportGO:00064063100%0.93%7.63E-7(1.23E-3)
mRNA transportGO:00510283100%0.93%7.63E-7(1.23E-3)
RNA transportGO:00506583100%1.08%1.22E-6(1.97E-3)
RNA-nucleus exportGO:00064053100%1.08%1.22E-6(1.97E-3)
nucleic acid transportGO:00506573100%1.08%1.22E-6(1.97E-3)
establishment of RNA localizationGO:00512363100%1.08%1.22E-6(1.97E-3)
nucleobase, nucleoside, nucleotide and nucleic acid transportGO:00159313100%1.21%1.7E-6(2.74E-3)
RNA localizationGO:00064033100%1.25%1.9E-6(3.08E-3)
nuclear exportGO:00511683100%1.29%2.05E-6(3.31E-3)
nuclear transportGO:00511693100%1.53%3.5E-6(5.65E-3)
nucleocytoplasmic transportGO:00069133100%1.63%4.18E-6(6.76E-3)
intracellular transportGO:00469073100%7.53%4.24E-4(0.69)
poly(A)+ mRNA-nucleus exportGO:0016973133.33%0.09%2.79E-3(n.s)
transportGO:00068103100%14.27%2.9E-3(n.s)
establishment of localizationGO:00512343100%14.39%2.97E-3(n.s)
localizationGO:00511793100%14.82%3.25E-3(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA helicase activityGO:0003724133.33%0.64%0.02(n.s)
helicase activityGO:0004386133.33%1.3%0.04(n.s)
molecular function unknownGO:0005554266.67%35.75%0.29(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nuclear poreGO:00056433100%0.77%4.37E-7(7.07E-4)
pore complexGO:00469303100%0.77%4.37E-7(7.07E-4)
nuclear membraneGO:00056353100%1.53%3.5E-6(5.65E-3)
integral to membraneGO:00160213100%3.55%4.41E-5(0.07)
intrinsic to membraneGO:00312243100%3.61%4.64E-5(0.08)
endomembrane systemGO:00125053100%3.7%5.01E-5(0.08)
organelle membraneGO:00310903100%8.58%6.29E-4(n.s)
membraneGO:00160203100%15.38%3.63E-3(n.s)
protein complexGO:00432343100%21.07%9.33E-3(n.s)
nucleusGO:00056343100%31.01%0.03(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
mitochondrionGO:0005739133.33%15.78%0.4(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_163 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
polyamine biosynthesisGO:00065962100%0.06%2.88E-7(4.65E-4)
polyamine metabolismGO:00065952100%0.11%1.01E-6(1.63E-3)
pantothenate biosynthesisGO:00159402100%0.12%1.34E-6(2.17E-3)
pantothenate metabolismGO:00159392100%0.12%1.34E-6(2.17E-3)
biogenic amine biosynthesisGO:00424012100%0.29%8.21E-6(0.01)
amino acid derivative biosynthesisGO:00423982100%0.31%9.12E-6(0.01)
biogenic amine metabolismGO:00065762100%0.39%1.44E-5(0.02)
amino acid derivative metabolismGO:00065752100%0.42%1.68E-5(0.03)
group transfer coenzyme metabolismGO:00067522100%0.68%4.54E-5(0.07)
coenzyme biosynthesisGO:00091082100%0.87%7.39E-5(0.12)
cofactor biosynthesisGO:00511882100%1.08%1.16E-4(0.19)
nitrogen compound biosynthesisGO:00442712100%1.67%2.77E-4(0.45)
amine biosynthesisGO:00093092100%1.67%2.77E-4(0.45)
coenzyme metabolismGO:00067322100%1.81%3.26E-4(0.53)
cofactor metabolismGO:00511862100%2.26%5.08E-4(0.82)
spermine biosynthesisGO:0006597150%0.03%6.2E-4(n.s)
spermidine biosynthesisGO:0008295150%0.03%6.2E-4(n.s)
spermine metabolismGO:0008215150%0.03%6.2E-4(n.s)
spermidine metabolismGO:0008216150%0.03%6.2E-4(n.s)
amino acid and derivative metabolismGO:00065192100%3.05%9.27E-4(n.s)
amine metabolismGO:00093082100%3.38%1.14E-3(n.s)
nitrogen compound metabolismGO:00068072100%3.66%1.33E-3(n.s)
cellular biosynthesisGO:00442492100%17.05%0.03(n.s)
biosynthesisGO:00090582100%18.28%0.03(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transferase activity, transferring alkyl or aryl (other than methyl) groupsGO:00167652100%0.53%2.69E-5(0.04)
spermine synthase activityGO:0016768150%0.02%**
spermidine synthase activityGO:0004766150%0.02%**
transferase activityGO:00167402100%10.13%0.01(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytoplasmGO:00057372100%55.64%0.31(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_119 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
iron ion homeostasisGO:00068792100%0.45%1.95E-5(0.03)
transition metal ion homeostasisGO:00469162100%0.73%5.19E-5(0.08)
di-, tri-valent inorganic cation homeostasisGO:00300052100%0.81%6.36E-5(0.1)
metal ion homeostasisGO:00068752100%0.91%8.21E-5(0.13)
cation homeostasisGO:00300032100%1.35%1.8E-4(0.29)
cell ion homeostasisGO:00068732100%1.49%2.19E-4(0.35)
ion homeostasisGO:00508012100%1.55%2.38E-4(0.38)
cell homeostasisGO:00197252100%1.64%2.67E-4(0.43)
homeostasisGO:00425922100%1.73%2.98E-4(0.48)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
integral to membraneGO:00160212100%3.55%1.25E-3(n.s)
intrinsic to membraneGO:00312242100%3.61%1.3E-3(n.s)
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_120 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ATP biosynthesisGO:00067542100%0.31%9.12E-6(0.01)
nucleoside phosphate metabolismGO:00067532100%0.31%9.12E-6(0.01)
energy coupled proton transport, down electrochemical gradientGO:00159852100%0.31%9.12E-6(0.01)
ATP synthesis coupled proton transportGO:00159862100%0.31%9.12E-6(0.01)
ATP metabolismGO:00460342100%0.31%9.12E-6(0.01)
purine nucleoside triphosphate metabolismGO:00091442100%0.34%1.11E-5(0.02)
purine ribonucleoside triphosphate metabolismGO:00092052100%0.34%1.11E-5(0.02)
purine nucleoside triphosphate biosynthesisGO:00091452100%0.34%1.11E-5(0.02)
purine ribonucleoside triphosphate biosynthesisGO:00092062100%0.34%1.11E-5(0.02)
ribonucleoside triphosphate biosynthesisGO:00092012100%0.36%1.21E-5(0.02)
ribonucleoside triphosphate metabolismGO:00091992100%0.36%1.21E-5(0.02)
nucleoside triphosphate biosynthesisGO:00091422100%0.37%1.32E-5(0.02)
hydrogen transportGO:00068182100%0.37%1.32E-5(0.02)
proton transportGO:00159922100%0.37%1.32E-5(0.02)
nucleoside triphosphate metabolismGO:00091412100%0.39%1.44E-5(0.02)
monovalent inorganic cation transportGO:00156722100%0.45%1.95E-5(0.03)
purine ribonucleotide biosynthesisGO:00091522100%0.57%3.2E-5(0.05)
ribonucleotide biosynthesisGO:00092602100%0.59%3.37E-5(0.05)
purine ribonucleotide metabolismGO:00091502100%0.6%3.56E-5(0.06)
ribonucleotide metabolismGO:00092592100%0.62%3.74E-5(0.06)
purine nucleotide biosynthesisGO:00061642100%0.65%4.13E-5(0.07)
group transfer coenzyme metabolismGO:00067522100%0.68%4.54E-5(0.07)
purine nucleotide metabolismGO:00061632100%0.7%4.75E-5(0.08)
oxidative phosphorylationGO:00061192100%0.71%4.97E-5(0.08)
nucleotide biosynthesisGO:00091652100%0.84%6.87E-5(0.11)
coenzyme biosynthesisGO:00091082100%0.87%7.39E-5(0.12)
cofactor biosynthesisGO:00511882100%1.08%1.16E-4(0.19)
cation transportGO:00068122100%1.36%1.84E-4(0.3)
nucleotide metabolismGO:00091172100%1.38%1.88E-4(0.3)
ion transportGO:00068112100%1.64%2.67E-4(0.43)
coenzyme metabolismGO:00067322100%1.81%3.26E-4(0.53)
phosphorylationGO:00163102100%2.21%4.87E-4(0.79)
cofactor metabolismGO:00511862100%2.26%5.08E-4(0.82)
phosphate metabolismGO:00067962100%2.91%8.44E-4(n.s)
phosphorus metabolismGO:00067932100%2.91%8.44E-4(n.s)
generation of precursor metabolites and energyGO:00060912100%3.5%1.22E-3(n.s)
response to waterGO:0009415150%0.15%3.1E-3(n.s)
response to water deprivationGO:0009414150%0.15%3.1E-3(n.s)
response to dessicationGO:0009269150%0.15%3.1E-3(n.s)
transportGO:00068102100%14.27%0.02(n.s)
establishment of localizationGO:00512342100%14.39%0.02(n.s)
localizationGO:00511792100%14.82%0.02(n.s)
cellular biosynthesisGO:00442492100%17.05%0.03(n.s)
biosynthesisGO:00090582100%18.28%0.03(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061392100%23.17%0.05(n.s)
response to abiotic stimulusGO:0009628150%3.52%0.07(n.s)
response to external stimulusGO:0009605150%3.87%0.08(n.s)
response to stressGO:0006950150%6.09%0.12(n.s)
response to stimulusGO:0050896150%8.41%0.16(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrogen-translocating F-type ATPase complexGO:00452552100%0.31%9.12E-6(0.01)
proton-transporting ATP synthase complexGO:00452592100%0.31%9.12E-6(0.01)
proton-transporting ATP synthase complex (sensu Eukaryota)GO:00057532100%0.31%9.12E-6(0.01)
proton-transporting two-sector ATPase complexGO:00164692100%0.31%9.12E-6(0.01)
mitochondrial inner membraneGO:00057432100%2.43%5.88E-4(0.95)
inner membraneGO:00198662100%2.43%5.88E-4(0.95)
mitochondrial membraneGO:00057402100%3.16%9.94E-4(n.s)
integral to membraneGO:00160212100%3.55%1.25E-3(n.s)
intrinsic to membraneGO:00312242100%3.61%1.3E-3(n.s)
organelle membraneGO:00310902100%8.58%7.35E-3(n.s)
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
protein complexGO:00432342100%21.07%0.04(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_121 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
external encapsulating structure organization and biogenesisGO:0045229150%2.17%0.04(n.s)
cell wall organization and biogenesisGO:0007047150%2.17%0.04(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein phosphatase type 2C activityGO:0015071150%0.09%1.86E-3(n.s)
protein serine/threonine phosphatase activityGO:0004722150%0.43%8.66E-3(n.s)
phosphoprotein phosphatase activityGO:0004721150%0.71%0.01(n.s)
phosphoric monoester hydrolase activityGO:0016791150%1.33%0.03(n.s)
phosphoric ester hydrolase activityGO:0042578150%1.44%0.03(n.s)
hydrolase activity, acting on ester bondsGO:0016788150%4.12%0.08(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cell cortexGO:0005938150%1.52%0.03(n.s)
integral to membraneGO:0016021150%3.55%0.07(n.s)
intrinsic to membraneGO:0031224150%3.61%0.07(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_122 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA recombinationGO:0006310150%2.91%0.06(n.s)
DNA metabolismGO:0006259150%8.58%0.16(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
endodeoxyribonuclease activityGO:0004520150%0.28%5.57E-3(n.s)
deoxyribonuclease activityGO:0004536150%0.31%6.19E-3(n.s)
endonuclease activityGO:0004519150%0.88%0.02(n.s)
nuclease activityGO:0004518150%2.15%0.04(n.s)
hydrolase activity, acting on ester bondsGO:0016788150%4.12%0.08(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_123 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
carnitine metabolismGO:00094373100%0.05%2.23E-11(3.6E-8)
biogenic amine metabolismGO:00065763100%0.39%5.13E-8(8.29E-5)
amino acid derivative metabolismGO:00065753100%0.42%6.53E-8(1.05E-4)
water-soluble vitamin metabolismGO:00067673100%1.13%1.39E-6(2.24E-3)
vitamin metabolismGO:00067663100%1.13%1.39E-6(2.24E-3)
amino acid and derivative metabolismGO:00065193100%3.05%2.8E-5(0.05)
amine metabolismGO:00093083100%3.38%3.8E-5(0.06)
nitrogen compound metabolismGO:00068073100%3.66%4.83E-5(0.08)
organic acid metabolismGO:00060823100%4.6%9.64E-5(0.16)
carboxylic acid metabolismGO:00197523100%4.6%9.64E-5(0.16)
alcohol metabolismGO:0006066266.67%2.43%1.73E-3(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
carnitine O-acyltransferase activityGO:00164063100%0.05%2.23E-11(3.6E-8)
carnitine O-acetyltransferase activityGO:00040923100%0.05%2.23E-11(3.6E-8)
O-acetyltransferase activityGO:00164133100%0.11%7.81E-10(1.26E-6)
O-acyltransferase activityGO:00083743100%0.25%1.25E-8(2.02E-5)
acetyltransferase activityGO:00164073100%0.71%3.39E-7(5.47E-4)
acyltransferase activityGO:00084153100%1.19%1.63E-6(2.64E-3)
transferase activity, transferring groups other than amino-acyl groupsGO:00167473100%1.19%1.63E-6(2.64E-3)
transferase activity, transferring acyl groupsGO:00167463100%1.43%2.8E-6(4.53E-3)
transferase activityGO:00167403100%10.13%1.04E-3(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
peroxisomal matrixGO:0005782133.33%0.2%6.03E-3(n.s)
peroxisomeGO:0005777133.33%0.87%0.03(n.s)
microbodyGO:0042579133.33%0.87%0.03(n.s)
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_124 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nitrogen utilizationGO:00197402100%0.22%4.37E-6(7.06E-3)
nitrogen compound metabolismGO:00068072100%3.66%1.33E-3(n.s)
transportGO:00068102100%14.27%0.02(n.s)
establishment of localizationGO:00512342100%14.39%0.02(n.s)
localizationGO:00511792100%14.82%0.02(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transporter activityGO:00052152100%6.64%4.41E-3(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
integral to membraneGO:0016021150%3.55%0.07(n.s)
intrinsic to membraneGO:0031224150%3.61%0.07(n.s)
plasma membraneGO:0005886150%3.67%0.07(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_125 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA elongation from RNA polymerase II promoterGO:00063684100%0.34%1.01E-10(1.63E-7)
RNA elongationGO:00063544100%0.36%1.22E-10(1.98E-7)
transcription from RNA polymerase II promoterGO:00063664100%4.29%3.32E-6(5.36E-3)
transcription, DNA-dependentGO:00063514100%6.78%2.09E-5(0.03)
transcriptionGO:00063504100%7.43%3.02E-5(0.05)
DNA packagingGO:0006323375%3.14%1.2E-4(0.19)
establishment and/or maintenance of chromatin architectureGO:0006325375%3.14%1.2E-4(0.19)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001375%3.72%1.97E-4(0.32)
chromosome organization and biogenesisGO:0051276375%3.9%2.28E-4(0.37)
regulation of transcription, DNA-dependentGO:0006355375%4.68%3.91E-4(0.63)
regulation of transcriptionGO:0045449375%4.96%4.65E-4(0.75)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219375%5.24%5.47E-4(0.88)
regulation of cellular metabolismGO:0031323375%5.98%8.11E-4(n.s)
chromatin assemblyGO:0031497250%1.27%9.41E-4(n.s)
regulation of metabolismGO:0019222375%6.37%9.76E-4(n.s)
chromatin assembly or disassemblyGO:0006333250%1.52%1.34E-3(n.s)
regulation of cellular physiological processGO:0051244375%8.49%2.28E-3(n.s)
regulation of cellular processGO:0050794375%8.52%2.3E-3(n.s)
DNA metabolismGO:0006259375%8.58%2.35E-3(n.s)
regulation of physiological processGO:0050791375%8.77%2.51E-3(n.s)
regulation of biological processGO:0050789375%8.97%2.68E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061394100%23.17%2.87E-3(n.s)
nucleosome assemblyGO:0006334125%0.08%3.1E-3(n.s)
organelle organization and biogenesisGO:0006996375%15.69%0.01(n.s)
cell organization and biogenesisGO:0016043375%17.98%0.02(n.s)
negative regulation of gene expression, epigeneticGO:0045814125%1.19%0.05(n.s)
chromatin silencingGO:0006342125%1.19%0.05(n.s)
gene silencingGO:0016458125%1.19%0.05(n.s)
heterochromatin formationGO:0031507125%1.19%0.05(n.s)
regulation of gene expression, epigeneticGO:0040029125%1.27%0.05(n.s)
biopolymer metabolismGO:0043283375%25.06%0.05(n.s)
primary metabolismGO:00442384100%48.71%0.06(n.s)
chromosome segregationGO:0007059125%1.6%0.06(n.s)
negative regulation of transcription, DNA-dependentGO:0045892125%1.89%0.07(n.s)
cellular metabolismGO:00442374100%52.12%0.07(n.s)
negative regulation of transcriptionGO:0016481125%1.95%0.08(n.s)
chromatin remodelingGO:0006338125%2.01%0.08(n.s)
metabolismGO:00081524100%52.93%0.08(n.s)
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045934125%2.11%0.08(n.s)
protein complex assemblyGO:0006461125%2.26%0.09(n.s)
negative regulation of cellular metabolismGO:0031324125%2.29%0.09(n.s)
negative regulation of metabolismGO:0009892125%2.4%0.09(n.s)
negative regulation of cellular physiological processGO:0051243125%2.59%0.1(n.s)
negative regulation of cellular processGO:0048523125%2.59%0.1(n.s)
negative regulation of physiological processGO:0043118125%2.62%0.1(n.s)
negative regulation of biological processGO:0048519125%2.71%0.1(n.s)
chromatin modificationGO:0016568125%2.77%0.11(n.s)
developmentGO:0007275125%5.73%0.21(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
cellular protein metabolismGO:0044267125%21.7%0.62(n.s)
protein metabolismGO:0019538125%22.06%0.63(n.s)
cellular macromolecule metabolismGO:0044260125%24.52%0.68(n.s)
macromolecule metabolismGO:0043170125%26.04%0.7(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA polymerase II transcription elongation factor activityGO:00169444100%0.26%3.29E-11(5.32E-8)
transcriptional elongation regulator activityGO:00037114100%0.34%1.01E-10(1.63E-7)
transcription regulator activityGO:00305284100%5%6.16E-6(9.95E-3)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transcription elongation factor complexGO:00080234100%0.29%5.36E-11(8.66E-8)
nucleoplasmGO:00056544100%4.86%5.49E-6(8.88E-3)
protein complexGO:00432344100%21.07%1.96E-3(n.s)
nucleusGO:00056344100%31.01%9.23E-3(n.s)
nuclear chromosome, telomeric regionGO:0000784125%0.36%0.01(n.s)
chromosome, telomeric regionGO:0000781125%0.4%0.02(n.s)
kinetochoreGO:0000776125%0.87%0.03(n.s)
chromosome, pericentric regionGO:0000775125%0.93%0.04(n.s)
nuclear chromosomeGO:0000228125%2.31%0.09(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
mitochondrionGO:0005739250%15.78%0.12(n.s)
chromosomeGO:0005694125%3.16%0.12(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
intracellular non-membrane-bound organelleGO:0043232125%14.3%0.46(n.s)
non-membrane-bound organelleGO:0043228125%14.3%0.46(n.s)
cellGO:00056234100%83.5%0.49(n.s)
cytoplasmGO:0005737250%55.64%0.77(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_126 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein-vacuolar targetingGO:0006623150%0.93%0.02(n.s)
protein targetingGO:0006605150%3.42%0.07(n.s)
intracellular protein transportGO:0006886150%3.7%0.07(n.s)
protein transportGO:0015031150%3.79%0.07(n.s)
establishment of protein localizationGO:0045184150%3.95%0.08(n.s)
protein localizationGO:0008104150%4.37%0.09(n.s)
intracellular transportGO:0046907150%7.53%0.14(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_127 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
fatty acid metabolismGO:00066312100%0.67%4.33E-5(0.07)
aerobic respirationGO:00090602100%1.27%1.59E-4(0.26)
cellular respirationGO:00453332100%1.35%1.8E-4(0.29)
energy derivation by oxidation of organic compoundsGO:00159802100%3.04%9.17E-4(n.s)
cellular lipid metabolismGO:00442552100%3.16%9.94E-4(n.s)
lipid metabolismGO:00066292100%3.38%1.14E-3(n.s)
generation of precursor metabolites and energyGO:00060912100%3.5%1.22E-3(n.s)
organic acid metabolismGO:00060822100%4.6%2.11E-3(n.s)
carboxylic acid metabolismGO:00197522100%4.6%2.11E-3(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
fatty-acid synthase activityGO:00043122100%0.12%1.34E-6(2.17E-3)
acyltransferase activityGO:00084152100%1.19%1.4E-4(0.23)
transferase activity, transferring groups other than amino-acyl groupsGO:00167472100%1.19%1.4E-4(0.23)
transferase activity, transferring acyl groupsGO:00167462100%1.43%2.01E-4(0.32)
malonyltransferase activityGO:0016420150%0.03%6.2E-4(n.s)
[acyl-carrier protein] S-malonyltransferase activityGO:0004314150%0.03%6.2E-4(n.s)
3-oxoacyl-[acyl-carrier protein] reductase activityGO:0004316150%0.03%6.2E-4(n.s)
S-malonyltransferase activityGO:0016419150%0.03%6.2E-4(n.s)
S-acyltransferase activityGO:0016417150%0.11%2.17E-3(n.s)
transferase activityGO:00167402100%10.13%0.01(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616150%1.07%0.02(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614150%1.18%0.02(n.s)
oxidoreductase activityGO:0016491150%3.73%0.07(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_128 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glutathione metabolismGO:0006749266.67%0.12%4.03E-6(6.51E-3)
sulfur metabolismGO:0006790266.67%0.87%2.2E-4(0.36)
coenzyme metabolismGO:0006732266.67%1.81%9.65E-4(n.s)
cofactor metabolismGO:0051186266.67%2.26%1.5E-3(n.s)
regulation of cell redox homeostasisGO:0030503133.33%0.15%4.64E-3(n.s)
cell redox homeostasisGO:0045454133.33%0.15%4.64E-3(n.s)
response to oxidative stressGO:0006979133.33%0.79%0.02(n.s)
oxygen and reactive oxygen species metabolismGO:0006800133.33%0.82%0.02(n.s)
response to biotic stimulusGO:0009607133.33%1.08%0.03(n.s)
cell homeostasisGO:0019725133.33%1.64%0.05(n.s)
homeostasisGO:0042592133.33%1.73%0.05(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
response to stressGO:0006950133.33%6.09%0.17(n.s)
response to stimulusGO:0050896133.33%8.41%0.23(n.s)
regulation of cellular physiological processGO:0051244133.33%8.49%0.23(n.s)
regulation of cellular processGO:0050794133.33%8.52%0.23(n.s)
regulation of physiological processGO:0050791133.33%8.77%0.24(n.s)
regulation of biological processGO:0050789133.33%8.97%0.25(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glutathione transferase activityGO:00043643100%0.06%8.92E-11(1.44E-7)
transferase activity, transferring alkyl or aryl (other than methyl) groupsGO:00167653100%0.53%1.33E-7(2.16E-4)
transferase activityGO:00167403100%10.13%1.04E-3(n.s)
glutathione peroxidase activityGO:0004602133.33%0.08%2.32E-3(n.s)
thiol-disulfide exchange intermediate activityGO:0030508133.33%0.12%3.71E-3(n.s)
disulfide oxidoreductase activityGO:0015036133.33%0.14%4.18E-3(n.s)
peroxidase activityGO:0004601133.33%0.26%7.88E-3(n.s)
oxidoreductase activity, acting on peroxide as acceptorGO:0016684133.33%0.26%7.88E-3(n.s)
antioxidant activityGO:0016209133.33%0.31%9.27E-3(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
oxidoreductase activityGO:0016491133.33%3.73%0.11(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
endoplasmic reticulumGO:0005783133.33%5.84%0.17(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
cytosolGO:0005829133.33%10.08%0.27(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_129 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tryptophanyl-tRNA aminoacylationGO:0006436150%0.03%6.2E-4(n.s)
pentose-phosphate shuntGO:0006098150%0.12%2.48E-3(n.s)
NADPH regenerationGO:0006740150%0.17%3.41E-3(n.s)
NADP metabolismGO:0006739150%0.19%3.71E-3(n.s)
hexose catabolismGO:0019320150%0.45%8.96E-3(n.s)
glucose catabolismGO:0006007150%0.45%8.96E-3(n.s)
tRNA aminoacylationGO:0043039150%0.46%9.27E-3(n.s)
amino acid activationGO:0043038150%0.46%9.27E-3(n.s)
nicotinamide metabolismGO:0006769150%0.46%9.27E-3(n.s)
tRNA aminoacylation for protein translationGO:0006418150%0.46%9.27E-3(n.s)
pyridine nucleotide metabolismGO:0019362150%0.51%0.01(n.s)
monosaccharide catabolismGO:0046365150%0.53%0.01(n.s)
alcohol catabolismGO:0046164150%0.57%0.01(n.s)
oxidoreduction coenzyme metabolismGO:0006733150%0.67%0.01(n.s)
glucose metabolismGO:0006006150%1.01%0.02(n.s)
tRNA modificationGO:0006400150%1.02%0.02(n.s)
main pathways of carbohydrate metabolismGO:0006092150%1.08%0.02(n.s)
cellular carbohydrate catabolismGO:0044275150%1.1%0.02(n.s)
carbohydrate catabolismGO:0016052150%1.1%0.02(n.s)
vitamin metabolismGO:0006766150%1.13%0.02(n.s)
water-soluble vitamin metabolismGO:0006767150%1.13%0.02(n.s)
hexose metabolismGO:0019318150%1.32%0.03(n.s)
nucleotide metabolismGO:0009117150%1.38%0.03(n.s)
monosaccharide metabolismGO:0005996150%1.43%0.03(n.s)
tRNA metabolismGO:0006399150%1.6%0.03(n.s)
coenzyme metabolismGO:0006732150%1.81%0.04(n.s)
cofactor metabolismGO:0051186150%2.26%0.04(n.s)
RNA modificationGO:0009451150%2.42%0.05(n.s)
alcohol metabolismGO:0006066150%2.43%0.05(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061392100%23.17%0.05(n.s)
amino acid metabolismGO:0006520150%2.82%0.06(n.s)
energy derivation by oxidation of organic compoundsGO:0015980150%3.04%0.06(n.s)
cellular macromolecule metabolismGO:00442602100%24.52%0.06(n.s)
amino acid and derivative metabolismGO:0006519150%3.05%0.06(n.s)
cellular carbohydrate metabolismGO:0044262150%3.08%0.06(n.s)
amine metabolismGO:0009308150%3.38%0.07(n.s)
carbohydrate metabolismGO:0005975150%3.38%0.07(n.s)
macromolecule metabolismGO:00431702100%26.04%0.07(n.s)
generation of precursor metabolites and energyGO:0006091150%3.5%0.07(n.s)
nitrogen compound metabolismGO:0006807150%3.66%0.07(n.s)
cellular macromolecule catabolismGO:0044265150%4.51%0.09(n.s)
organic acid metabolismGO:0006082150%4.6%0.09(n.s)
carboxylic acid metabolismGO:0019752150%4.6%0.09(n.s)
macromolecule catabolismGO:0009057150%4.83%0.09(n.s)
cellular catabolismGO:0044248150%5.84%0.11(n.s)
catabolismGO:0009056150%6.16%0.12(n.s)
translationGO:0043037150%6.47%0.13(n.s)
RNA metabolismGO:0016070150%8.32%0.16(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
protein biosynthesisGO:0006412150%12.16%0.23(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
macromolecule biosynthesisGO:0009059150%13.04%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribulose-phosphate 3-epimerase activityGO:0004750150%0.02%**
racemase and epimerase activity, acting on carbohydrates and derivativesGO:0016857150%0.03%6.2E-4(n.s)
tryptophan-tRNA ligase activityGO:0004830150%0.03%6.2E-4(n.s)
racemase and epimerase activityGO:0016854150%0.06%1.24E-3(n.s)
ligase activity, forming carbon-oxygen bondsGO:0016875150%0.56%0.01(n.s)
tRNA ligase activityGO:0004812150%0.56%0.01(n.s)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876150%0.56%0.01(n.s)
RNA ligase activityGO:0008452150%0.57%0.01(n.s)
ligase activity, forming phosphoric ester bondsGO:0016886150%0.62%0.01(n.s)
isomerase activityGO:0016853150%0.81%0.02(n.s)
ligase activityGO:0016874150%1.89%0.04(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytosolGO:0005829150%10.08%0.19(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_118 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
rRNA modificationGO:0000154150%1.38%0.03(n.s)
RNA modificationGO:0009451150%2.42%0.05(n.s)
rRNA metabolismGO:0016072150%3.92%0.08(n.s)
RNA metabolismGO:0016070150%8.32%0.16(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
protein biosynthesisGO:0006412150%12.16%0.23(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
macromolecule biosynthesisGO:0009059150%13.04%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribosome bindingGO:0043022150%0.02%**
rRNA (uridine) methyltransferase activityGO:0016436150%0.03%6.2E-4(n.s)
rRNA (uridine-2'-O-)-methyltransferase activityGO:0008650150%0.03%6.2E-4(n.s)
rRNA methyltransferase activityGO:0008649150%0.06%1.24E-3(n.s)
ribonucleoprotein bindingGO:0043021150%0.09%1.86E-3(n.s)
RNA methyltransferase activityGO:0008173150%0.31%6.19E-3(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:0008757150%0.77%0.02(n.s)
GTPase activityGO:0003924150%0.91%0.02(n.s)
methyltransferase activityGO:0008168150%1.1%0.02(n.s)
transferase activity, transferring one-carbon groupsGO:0016741150%1.13%0.02(n.s)
nucleoside-triphosphatase activityGO:0017111150%3.42%0.07(n.s)
pyrophosphatase activityGO:0016462150%3.67%0.07(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817150%3.69%0.07(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818150%3.69%0.07(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
bindingGO:0005488150%17.35%0.32(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
extrinsic to membraneGO:0019898150%0.48%9.58E-3(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_59 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
thiosulfate sulfurtransferase activityGO:0004792150%0.02%**
transferase activity, transferring sulfur-containing groupsGO:0016782150%0.03%6.2E-4(n.s)
sulfurtransferase activityGO:0016783150%0.03%6.2E-4(n.s)
cysteine synthase activityGO:0004124150%0.03%6.2E-4(n.s)
carbon-oxygen lyase activityGO:0016835150%0.56%0.01(n.s)
lyase activityGO:0016829150%1.27%0.03(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_55 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
phosphate transportGO:0006817150%0.15%3.1E-3(n.s)
inorganic anion transportGO:0015698150%0.25%4.95E-3(n.s)
anion transportGO:0006820150%0.26%5.26E-3(n.s)
ion transportGO:0006811150%1.64%0.03(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
phosphate transporter activityGO:0015114150%0.12%2.48E-3(n.s)
inorganic anion transporter activityGO:0015103150%0.2%4.02E-3(n.s)
anion transporter activityGO:0008509150%0.28%5.57E-3(n.s)
ion transporter activityGO:0015075150%2.21%0.04(n.s)
transporter activityGO:0005215150%6.64%0.13(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
membraneGO:0016020150%15.38%0.28(n.s)
cellular component unknownGO:0008372150%15.74%0.29(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
intracellularGO:0005622150%77.03%0.95(n.s)
cellGO:0005623150%83.5%0.97(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_57 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transition metal ion transportGO:00000413100%0.67%2.75E-7(4.45E-4)
di-, tri-valent inorganic cation transportGO:00156743100%0.79%4.65E-7(7.51E-4)
metal ion transportGO:00300013100%0.87%6.18E-7(9.99E-4)
cation transportGO:00068123100%1.36%2.45E-6(3.96E-3)
ion transportGO:00068113100%1.64%4.3E-6(6.95E-3)
copper ion transportGO:0006825266.67%0.2%1.12E-5(0.02)
iron ion homeostasisGO:0006879266.67%0.45%5.83E-5(0.09)
transition metal ion homeostasisGO:0046916266.67%0.73%1.55E-4(0.25)
di-, tri-valent inorganic cation homeostasisGO:0030005266.67%0.81%1.9E-4(0.31)
metal ion homeostasisGO:0006875266.67%0.91%2.45E-4(0.4)
cation homeostasisGO:0030003266.67%1.35%5.34E-4(0.86)
cell ion homeostasisGO:0006873266.67%1.49%6.5E-4(n.s)
ion homeostasisGO:0050801266.67%1.55%7.05E-4(n.s)
cell homeostasisGO:0019725266.67%1.64%7.93E-4(n.s)
homeostasisGO:0042592266.67%1.73%8.85E-4(n.s)
high affinity iron ion transportGO:0006827133.33%0.08%2.32E-3(n.s)
intracellular copper ion transportGO:0015680133.33%0.09%2.79E-3(n.s)
transportGO:00068103100%14.27%2.9E-3(n.s)
establishment of localizationGO:00512343100%14.39%2.97E-3(n.s)
localizationGO:00511793100%14.82%3.25E-3(n.s)
iron ion transportGO:0006826133.33%0.29%8.8E-3(n.s)
response to oxidative stressGO:0006979133.33%0.79%0.02(n.s)
oxygen and reactive oxygen species metabolismGO:0006800133.33%0.82%0.02(n.s)
response to biotic stimulusGO:0009607133.33%1.08%0.03(n.s)
response to stressGO:0006950133.33%6.09%0.17(n.s)
intracellular transportGO:0046907133.33%7.53%0.21(n.s)
response to stimulusGO:0050896133.33%8.41%0.23(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cation transporter activityGO:00083243100%1.89%6.59E-6(0.01)
ion transporter activityGO:00150753100%2.21%1.06E-5(0.02)
transition metal ion transporter activityGO:0046915266.67%0.42%5.04E-5(0.08)
di-, tri-valent inorganic cation transporter activityGO:0015082266.67%0.54%8.54E-5(0.14)
metal ion transporter activityGO:0046873266.67%0.59%1.01E-4(0.16)
transporter activityGO:00052153100%6.64%2.92E-4(0.47)
copper chaperone activityGO:0016531133.33%0.05%1.39E-3(n.s)
metallochaperone activityGO:0016530133.33%0.06%1.86E-3(n.s)
copper ion transporter activityGO:0005375133.33%0.09%2.79E-3(n.s)
iron ion transporter activityGO:0005381133.33%0.15%4.64E-3(n.s)
cation-transporting ATPase activityGO:0019829133.33%0.26%7.88E-3(n.s)
ATPase activity, coupled to transmembrane movement of ionsGO:0042625133.33%0.46%0.01(n.s)
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesGO:0016820133.33%0.87%0.03(n.s)
ATPase activity, coupled to transmembrane movement of substancesGO:0042626133.33%0.87%0.03(n.s)
ATPase activity, coupledGO:0042623133.33%1.58%0.05(n.s)
ATPase activityGO:0016887133.33%2.52%0.07(n.s)
nucleoside-triphosphatase activityGO:0017111133.33%3.42%0.1(n.s)
pyrophosphatase activityGO:0016462133.33%3.67%0.11(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817133.33%3.69%0.11(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818133.33%3.69%0.11(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytoplasmic vesicle membraneGO:0030659133.33%0.02%**
trans-Golgi network transport vesicle membraneGO:0012510133.33%0.02%**
coated vesicle membraneGO:0030662133.33%0.02%**
clathrin coated vesicle membraneGO:0030665133.33%0.02%**
vesicle membraneGO:0012506133.33%0.02%**
transport vesicle membraneGO:0030658133.33%0.02%**
Golgi vesicle membraneGO:0030660133.33%0.02%**
trans-Golgi network transport vesicleGO:0030140133.33%0.12%3.71E-3(n.s)
transport vesicleGO:0030133133.33%0.19%5.57E-3(n.s)
clathrin-coated vesicleGO:0030136133.33%0.25%7.42E-3(n.s)
Golgi vesicleGO:0005798133.33%0.26%7.88E-3(n.s)
Golgi membraneGO:0000139133.33%0.39%0.01(n.s)
coated vesicleGO:0030135133.33%0.79%0.02(n.s)
cytoplasmic vesicleGO:0031410133.33%1.16%0.03(n.s)
cytoplasmic membrane-bound vesicleGO:0016023133.33%1.16%0.03(n.s)
Golgi apparatusGO:0005794133.33%2.01%0.06(n.s)
membraneGO:0016020266.67%15.38%0.06(n.s)
plasma membraneGO:0005886133.33%3.67%0.11(n.s)
endomembrane systemGO:0012505133.33%3.7%0.11(n.s)
organelle membraneGO:0031090133.33%8.58%0.24(n.s)
cytosolGO:0005829133.33%10.08%0.27(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cytoplasmGO:0005737266.67%55.64%0.58(n.s)
intracellularGO:0005622266.67%77.03%0.87(n.s)
intracellular membrane-bound organelleGO:0043231133.33%55.65%0.91(n.s)
membrane-bound organelleGO:0043227133.33%55.65%0.91(n.s)
organelleGO:0043226133.33%60.56%0.94(n.s)
intracellular organelleGO:0043229133.33%60.56%0.94(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_56 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
pigment biosynthesisGO:0046148375%0.22%3.24E-8(5.24E-5)
porphyrin biosynthesisGO:0006779375%0.22%3.24E-8(5.24E-5)
heme biosynthesisGO:0006783375%0.22%3.24E-8(5.24E-5)
porphyrin metabolismGO:0006778375%0.23%4.05E-8(6.55E-5)
heme metabolismGO:0042168375%0.23%4.05E-8(6.55E-5)
pigment metabolismGO:0042440375%0.23%4.05E-8(6.55E-5)
secondary metabolismGO:0019748375%0.28%7.27E-8(1.17E-4)
cofactor biosynthesisGO:0051188375%1.08%4.85E-6(7.83E-3)
heterocycle metabolismGO:0046483375%1.1%5.06E-6(8.18E-3)
cofactor metabolismGO:0051186375%2.26%4.46E-5(0.07)
cytochrome c-heme linkageGO:0018063125%0.05%1.86E-3(n.s)
protein-heme linkageGO:0017003125%0.05%1.86E-3(n.s)
protein-tetrapyrrole linkageGO:0017006125%0.05%1.86E-3(n.s)
cytochrome complex assemblyGO:0017004125%0.08%3.1E-3(n.s)
cellular biosynthesisGO:0044249375%17.05%0.02(n.s)
biosynthesisGO:0009058375%18.28%0.02(n.s)
cellular metabolismGO:00442374100%52.12%0.07(n.s)
metabolismGO:00081524100%52.93%0.08(n.s)
protein complex assemblyGO:0006461125%2.26%0.09(n.s)
protein modificationGO:0006464125%6.68%0.24(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
biopolymer modificationGO:0043412125%9.25%0.32(n.s)
cellular protein metabolismGO:0044267125%21.7%0.62(n.s)
protein metabolismGO:0019538125%22.06%0.63(n.s)
cellular macromolecule metabolismGO:0044260125%24.52%0.68(n.s)
biopolymer metabolismGO:0043283125%25.06%0.68(n.s)
macromolecule metabolismGO:0043170125%26.04%0.7(n.s)
primary metabolismGO:0044238125%48.71%0.93(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptorGO:0016634250%0.05%8.64E-7(1.4E-3)
oxidoreductase activity, acting on the CH-CH group of donorsGO:0016627250%0.29%4.91E-5(0.08)
protoporphyrinogen oxidase activityGO:0004729125%0.02%**
coproporphyrinogen oxidase activityGO:0004109125%0.02%**
lyase activityGO:0016829250%1.27%9.41E-4(n.s)
ferrochelatase activityGO:0004325125%0.03%1.24E-3(n.s)
holocytochrome-c synthase activityGO:0004408125%0.03%1.24E-3(n.s)
carbon-sulfur lyase activityGO:0016846125%0.14%5.57E-3(n.s)
catalytic activityGO:00038244100%29.21%7.27E-3(n.s)
oxidoreductase activityGO:0016491250%3.73%7.92E-3(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057394100%15.78%6.18E-4(1)
mitochondrial inner membraneGO:0005743250%2.43%3.41E-3(n.s)
inner membraneGO:0019866250%2.43%3.41E-3(n.s)
mitochondrial membraneGO:0005740250%3.16%5.72E-3(n.s)
mitochondrial intermembrane spaceGO:0005758125%0.39%0.02(n.s)
organelle membraneGO:0031090250%8.58%0.04(n.s)
cytoplasmGO:00057374100%55.64%0.1(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
membraneGO:0016020250%15.38%0.11(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cellGO:00056234100%83.5%0.49(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_50 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
retrograde transport, endosome to GolgiGO:0042147250%0.15%1.29E-5(0.02)
Golgi to vacuole transportGO:0006896250%0.28%4.39E-5(0.07)
endosome organization and biogenesisGO:0007032250%0.56%1.8E-4(0.29)
endosome transportGO:0016197250%0.56%1.8E-4(0.29)
vacuolar transportGO:0007034250%0.73%3.08E-4(0.5)
post-Golgi transportGO:0006892250%0.79%3.63E-4(0.59)
Golgi vesicle transportGO:0048193250%2.18%2.76E-3(n.s)
secretory pathwayGO:0045045250%3.13%5.61E-3(n.s)
secretionGO:0046903250%3.24%5.99E-3(n.s)
vesicle-mediated transportGO:0016192250%4.34%0.01(n.s)
intracellular transportGO:0046907250%7.53%0.03(n.s)
transportGO:0006810250%14.27%0.1(n.s)
establishment of localizationGO:0051234250%14.39%0.1(n.s)
localizationGO:0051179250%14.82%0.11(n.s)
organelle organization and biogenesisGO:0006996250%15.69%0.12(n.s)
cell organization and biogenesisGO:0016043250%17.98%0.15(n.s)
biological process unknownGO:0000004250%25.64%0.27(n.s)
cellular physiological processGO:0050875250%71.65%0.93(n.s)
cellular processGO:0009987250%72.29%0.93(n.s)
physiological processGO:0007582250%73.68%0.94(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:0005554375%35.75%0.13(n.s)
protein bindingGO:0005515125%7.39%0.26(n.s)
bindingGO:0005488125%17.35%0.53(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
GARP complexGO:0000938250%0.06%1.73E-6(2.79E-3)
cytoplasmic vesicleGO:0031410250%1.16%7.87E-4(n.s)
cytoplasmic membrane-bound vesicleGO:0016023250%1.16%7.87E-4(n.s)
Golgi apparatusGO:0005794250%2.01%2.35E-3(n.s)
mitochondrionGO:0005739375%15.78%0.01(n.s)
cytoplasmGO:00057374100%55.64%0.1(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
plasma membraneGO:0005886125%3.67%0.14(n.s)
protein complexGO:0043234250%21.07%0.2(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cellGO:00056234100%83.5%0.49(n.s)
membraneGO:0016020125%15.38%0.49(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_53 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lysyl-tRNA aminoacylationGO:0006430150%0.03%6.2E-4(n.s)
mitochondrial matrix protein importGO:0030150150%0.31%6.19E-3(n.s)
tRNA aminoacylationGO:0043039150%0.46%9.27E-3(n.s)
amino acid activationGO:0043038150%0.46%9.27E-3(n.s)
tRNA aminoacylation for protein translationGO:0006418150%0.46%9.27E-3(n.s)
protein-mitochondrial targetingGO:0006626150%0.73%0.01(n.s)
tRNA modificationGO:0006400150%1.02%0.02(n.s)
protein foldingGO:0006457150%1.04%0.02(n.s)
protein importGO:0017038150%1.39%0.03(n.s)
mitochondrion organization and biogenesisGO:0007005150%1.47%0.03(n.s)
tRNA metabolismGO:0006399150%1.6%0.03(n.s)
cellular protein metabolismGO:00442672100%21.7%0.05(n.s)
RNA modificationGO:0009451150%2.42%0.05(n.s)
protein metabolismGO:00195382100%22.06%0.05(n.s)
amino acid metabolismGO:0006520150%2.82%0.06(n.s)
cellular macromolecule metabolismGO:00442602100%24.52%0.06(n.s)
amino acid and derivative metabolismGO:0006519150%3.05%0.06(n.s)
amine metabolismGO:0009308150%3.38%0.07(n.s)
protein targetingGO:0006605150%3.42%0.07(n.s)
macromolecule metabolismGO:00431702100%26.04%0.07(n.s)
nitrogen compound metabolismGO:0006807150%3.66%0.07(n.s)
intracellular protein transportGO:0006886150%3.7%0.07(n.s)
protein transportGO:0015031150%3.79%0.07(n.s)
establishment of protein localizationGO:0045184150%3.95%0.08(n.s)
protein localizationGO:0008104150%4.37%0.09(n.s)
organic acid metabolismGO:0006082150%4.6%0.09(n.s)
carboxylic acid metabolismGO:0019752150%4.6%0.09(n.s)
translationGO:0043037150%6.47%0.13(n.s)
intracellular transportGO:0046907150%7.53%0.14(n.s)
RNA metabolismGO:0016070150%8.32%0.16(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
protein biosynthesisGO:0006412150%12.16%0.23(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
macromolecule biosynthesisGO:0009059150%13.04%0.24(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lysine-tRNA ligase activityGO:0004824150%0.03%6.2E-4(n.s)
ligase activity, forming carbon-oxygen bondsGO:0016875150%0.56%0.01(n.s)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876150%0.56%0.01(n.s)
tRNA ligase activityGO:0004812150%0.56%0.01(n.s)
RNA ligase activityGO:0008452150%0.57%0.01(n.s)
ligase activity, forming phosphoric ester bondsGO:0016886150%0.62%0.01(n.s)
ligase activityGO:0016874150%1.89%0.04(n.s)
protein bindingGO:0005515150%7.39%0.14(n.s)
bindingGO:0005488150%17.35%0.32(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial matrixGO:0005759150%2.52%0.05(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_52 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
response to antibioticGO:0046677133.33%0.02%**
response to drugGO:0042493133.33%0.48%0.01(n.s)
response to stimulusGO:0050896266.67%8.41%0.02(n.s)
protein-vacuolar targetingGO:0006623133.33%0.93%0.03(n.s)
response to chemical substanceGO:0042221133.33%2.18%0.06(n.s)
DNA repairGO:0006281133.33%2.32%0.07(n.s)
response to DNA damage stimulusGO:0006974133.33%2.73%0.08(n.s)
response to endogenous stimulusGO:0009719133.33%2.82%0.08(n.s)
carbohydrate metabolismGO:0005975133.33%3.38%0.1(n.s)
protein targetingGO:0006605133.33%3.42%0.1(n.s)
response to abiotic stimulusGO:0009628133.33%3.52%0.1(n.s)
intracellular protein transportGO:0006886133.33%3.7%0.11(n.s)
protein transportGO:0015031133.33%3.79%0.11(n.s)
response to external stimulusGO:0009605133.33%3.87%0.11(n.s)
establishment of protein localizationGO:0045184133.33%3.95%0.11(n.s)
protein localizationGO:0008104133.33%4.37%0.13(n.s)
response to stressGO:0006950133.33%6.09%0.17(n.s)
intracellular transportGO:0046907133.33%7.53%0.21(n.s)
DNA metabolismGO:0006259133.33%8.58%0.24(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139133.33%23.17%0.55(n.s)
biopolymer metabolismGO:0043283133.33%25.06%0.58(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
bindingGO:00054883100%17.35%5.21E-3(n.s)
transcription coactivator activityGO:0003713133.33%0.19%5.57E-3(n.s)
transcription regulator activityGO:0030528266.67%5%7.24E-3(n.s)
cysteine-type peptidase activityGO:0008234133.33%0.43%0.01(n.s)
protein bindingGO:0005515266.67%7.39%0.02(n.s)
transcription cofactor activityGO:0003712133.33%0.56%0.02(n.s)
transcription factor bindingGO:0008134133.33%0.6%0.02(n.s)
peptidase activityGO:0008233133.33%2.48%0.07(n.s)
nucleic acid bindingGO:0003676133.33%9.87%0.27(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
endosomeGO:0005768133.33%1.07%0.03(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
mitochondrionGO:0005739133.33%15.78%0.4(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_164 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
regulation of carbohydrate metabolismGO:00061094100%0.42%2.43E-10(3.92E-7)
energy derivation by oxidation of organic compoundsGO:00159804100%3.04%8.25E-7(1.33E-3)
carbohydrate metabolismGO:00059754100%3.38%1.27E-6(2.05E-3)
generation of precursor metabolites and energyGO:00060914100%3.5%1.46E-6(2.37E-3)
regulation of metabolismGO:00192224100%6.37%1.62E-5(0.03)
transcriptionGO:00063504100%7.43%3.02E-5(0.05)
regulation of physiological processGO:00507914100%8.77%5.85E-5(0.09)
regulation of biological processGO:00507894100%8.97%6.41E-5(0.1)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061394100%23.17%2.87E-3(n.s)
macromolecule metabolismGO:00431704100%26.04%4.58E-3(n.s)
primary metabolismGO:00442384100%48.71%0.06(n.s)
cellular metabolismGO:00442374100%52.12%0.07(n.s)
metabolismGO:00081524100%52.93%0.08(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transcriptional activator activityGO:00165634100%0.53%6.41E-10(1.04E-6)
transcription regulator activityGO:00305284100%5%6.16E-6(9.95E-3)
DNA bindingGO:0003677125%3.18%0.12(n.s)
nucleic acid bindingGO:0003676125%9.87%0.34(n.s)
bindingGO:0005488125%17.35%0.53(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
CCAAT-binding factor complexGO:00166024100%0.06%1.38E-14(2.23E-11)
transcription factor complexGO:00056674100%1.87%1.17E-7(1.9E-4)
nucleoplasmGO:00056544100%4.86%5.49E-6(8.88E-3)
protein complexGO:00432344100%21.07%1.96E-3(n.s)
nucleusGO:00056344100%31.01%9.23E-3(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cellGO:00056234100%83.5%0.49(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_114 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial fusionGO:0008053150%0.06%1.24E-3(n.s)
organelle fusionGO:0048284150%0.26%5.26E-3(n.s)
mitochondrion organization and biogenesisGO:0007005150%1.47%0.03(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_88 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
monovalent inorganic cation transportGO:0015672150%0.45%8.96E-3(n.s)
cation transportGO:0006812150%1.36%0.03(n.s)
ion transportGO:0006811150%1.64%0.03(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
potassium:hydrogen antiporter activityGO:0015386150%0.02%**
monovalent cation:proton antiporter activityGO:0005451150%0.03%6.2E-4(n.s)
potassium ion transporter activityGO:0015079150%0.05%9.29E-4(n.s)
cation:cation antiporter activityGO:0015491150%0.06%1.24E-3(n.s)
antiporter activityGO:0015297150%0.14%2.79E-3(n.s)
porter activityGO:0015291150%0.59%0.01(n.s)
metal ion transporter activityGO:0046873150%0.59%0.01(n.s)
electrochemical potential-driven transporter activityGO:0015290150%0.59%0.01(n.s)
hydrogen ion transporter activityGO:0015078150%0.84%0.02(n.s)
monovalent inorganic cation transporter activityGO:0015077150%0.88%0.02(n.s)
carrier activityGO:0005386150%1.64%0.03(n.s)
cation transporter activityGO:0008324150%1.89%0.04(n.s)
ion transporter activityGO:0015075150%2.21%0.04(n.s)
transporter activityGO:0005215150%6.64%0.13(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_89 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial intermembrane space protein importGO:0045041150%0.09%1.86E-3(n.s)
protein-mitochondrial targetingGO:0006626150%0.73%0.01(n.s)
transportGO:00068102100%14.27%0.02(n.s)
establishment of localizationGO:00512342100%14.39%0.02(n.s)
localizationGO:00511792100%14.82%0.02(n.s)
protein importGO:0017038150%1.39%0.03(n.s)
protein targetingGO:0006605150%3.42%0.07(n.s)
intracellular protein transportGO:0006886150%3.7%0.07(n.s)
protein transportGO:0015031150%3.79%0.07(n.s)
establishment of protein localizationGO:0045184150%3.95%0.08(n.s)
vesicle-mediated transportGO:0016192150%4.34%0.08(n.s)
protein localizationGO:0008104150%4.37%0.09(n.s)
intracellular transportGO:0046907150%7.53%0.14(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
Rab GTPase activator activityGO:0005097150%0.11%2.17E-3(n.s)
GTPase activator activityGO:0005096150%0.48%9.58E-3(n.s)
small GTPase regulator activityGO:0005083150%0.88%0.02(n.s)
enzyme activator activityGO:0008047150%0.91%0.02(n.s)
GTPase regulator activityGO:0030695150%1.04%0.02(n.s)
enzyme regulator activityGO:0030234150%2.54%0.05(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_111 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
response to oxidative stressGO:00069793100%0.79%4.65E-7(7.51E-4)
oxygen and reactive oxygen species metabolismGO:00068003100%0.82%5.23E-7(8.45E-4)
response to biotic stimulusGO:00096073100%1.08%1.22E-6(1.97E-3)
response to stressGO:00069503100%6.09%2.24E-4(0.36)
response to stimulusGO:00508963100%8.41%5.92E-4(0.96)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptorGO:0016668266.67%0.09%2.16E-6(3.49E-3)
disulfide oxidoreductase activityGO:0015036266.67%0.14%5.18E-6(8.37E-3)
oxidoreductase activity, acting on sulfur group of donorsGO:0016667266.67%0.19%9.49E-6(0.02)
antioxidant activityGO:0016209266.67%0.31%2.73E-5(0.04)
electron transporter activityGO:0005489266.67%0.34%3.32E-5(0.05)
oxidoreductase activityGO:00164913100%3.73%5.14E-5(0.08)
peptide disulfide oxidoreductase activityGO:0015037133.33%0.02%**
glutathione-disulfide reductase activityGO:0004362133.33%0.02%**
glutathione disulfide oxidoreductase activityGO:0015038133.33%0.02%**
thioredoxin-disulfide reductase activityGO:0004791133.33%0.03%9.29E-4(n.s)
thiol-disulfide exchange intermediate activityGO:0030508133.33%0.12%3.71E-3(n.s)
transporter activityGO:0005215266.67%6.64%0.01(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
nucleusGO:0005634133.33%31.01%0.67(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_110 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
phospholipase activityGO:0004620150%0.14%2.79E-3(n.s)
lipase activityGO:0016298150%0.28%5.57E-3(n.s)
carboxylic ester hydrolase activityGO:0016789150%0.46%9.27E-3(n.s)
hydrolase activity, acting on ester bondsGO:0016788150%4.12%0.08(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_113 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
S-adenosylmethionine transportGO:0015805150%0.03%6.2E-4(n.s)
biotin metabolismGO:0006768150%0.06%1.24E-3(n.s)
biotin biosynthesisGO:0009102150%0.06%1.24E-3(n.s)
sulfur amino acid transportGO:0000101150%0.08%1.55E-3(n.s)
sulfur compound biosynthesisGO:0044272150%0.23%4.64E-3(n.s)
amino acid transportGO:0006865150%0.57%0.01(n.s)
vitamin biosynthesisGO:0009110150%0.59%0.01(n.s)
water-soluble vitamin biosynthesisGO:0042364150%0.59%0.01(n.s)
amine transportGO:0015837150%0.74%0.01(n.s)
carboxylic acid transportGO:0046942150%0.77%0.02(n.s)
organic acid transportGO:0015849150%0.79%0.02(n.s)
sulfur metabolismGO:0006790150%0.87%0.02(n.s)
heterocycle metabolismGO:0046483150%1.1%0.02(n.s)
water-soluble vitamin metabolismGO:0006767150%1.13%0.02(n.s)
vitamin metabolismGO:0006766150%1.13%0.02(n.s)
cofactor metabolismGO:0051186150%2.26%0.04(n.s)
organic acid metabolismGO:0006082150%4.6%0.09(n.s)
carboxylic acid metabolismGO:0019752150%4.6%0.09(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biotin synthase activityGO:0004076150%0.02%**
transferase activity, transferring sulfur-containing groupsGO:0016782150%0.03%6.2E-4(n.s)
S-adenosylmethionine transporter activityGO:0000095150%0.03%6.2E-4(n.s)
sulfurtransferase activityGO:0016783150%0.03%6.2E-4(n.s)
sulfur amino acid transporter activityGO:0000099150%0.09%1.86E-3(n.s)
cofactor transporter activityGO:0051184150%0.12%2.48E-3(n.s)
amino acid transporter activityGO:0015171150%0.5%9.89E-3(n.s)
amine transporter activityGO:0005275150%0.64%0.01(n.s)
carboxylic acid transporter activityGO:0046943150%0.74%0.01(n.s)
organic acid transporter activityGO:0005342150%0.79%0.02(n.s)
transporter activityGO:0005215150%6.64%0.13(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_112 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial genome maintenanceGO:00000022100%0.42%1.68E-5(0.03)
mitochondrion organization and biogenesisGO:00070052100%1.47%2.14E-4(0.35)
DNA metabolismGO:00062592100%8.58%7.35E-3(n.s)
telomere maintenanceGO:0000723150%0.65%0.01(n.s)
organelle organization and biogenesisGO:00069962100%15.69%0.02(n.s)
DNA replicationGO:0006260150%1.6%0.03(n.s)
cell organization and biogenesisGO:00160432100%17.98%0.03(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061392100%23.17%0.05(n.s)
DNA recombinationGO:0006310150%2.91%0.06(n.s)
biopolymer metabolismGO:00432832100%25.06%0.06(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001150%3.72%0.07(n.s)
chromosome organization and biogenesisGO:0051276150%3.9%0.08(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA helicase activityGO:00036782100%0.43%1.81E-5(0.03)
helicase activityGO:00043862100%1.3%1.67E-4(0.27)
ATP-dependent DNA helicase activityGO:0004003150%0.15%3.1E-3(n.s)
DNA-dependent ATPase activityGO:0008094150%0.26%5.26E-3(n.s)
ATP-dependent helicase activityGO:0008026150%0.57%0.01(n.s)
ATPase activity, coupledGO:0042623150%1.58%0.03(n.s)
ATPase activityGO:0016887150%2.52%0.05(n.s)
nucleoside-triphosphatase activityGO:0017111150%3.42%0.07(n.s)
pyrophosphatase activityGO:0016462150%3.67%0.07(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817150%3.69%0.07(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818150%3.69%0.07(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nuclear heterochromatinGO:0005720150%0.11%2.17E-3(n.s)
nuclear telomeric heterochromatinGO:0005724150%0.11%2.17E-3(n.s)
heterochromatinGO:0000792150%0.11%2.17E-3(n.s)
nuclear chromosome, telomeric regionGO:0000784150%0.36%7.11E-3(n.s)
chromosome, telomeric regionGO:0000781150%0.4%8.04E-3(n.s)
nuclear chromatinGO:0000790150%0.56%0.01(n.s)
chromatinGO:0000785150%0.59%0.01(n.s)
nuclear chromosomeGO:0000228150%2.31%0.05(n.s)
chromosomeGO:0005694150%3.16%0.06(n.s)
nucleusGO:00056342100%31.01%0.1(n.s)
intracellular non-membrane-bound organelleGO:0043232150%14.3%0.27(n.s)
non-membrane-bound organelleGO:0043228150%14.3%0.27(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_82 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cellular response to nitrogen starvationGO:0006995125%0.08%3.1E-3(n.s)
cellular response to starvationGO:0009267125%0.2%8.03E-3(n.s)
response to starvationGO:0042594125%0.2%8.03E-3(n.s)
transcription from RNA polymerase II promoterGO:0006366250%4.29%0.01(n.s)
cell adhesionGO:0007155125%0.28%0.01(n.s)
response to extracellular stimulusGO:0009991125%0.31%0.01(n.s)
regulation of carbohydrate metabolismGO:0006109125%0.42%0.02(n.s)
replicative cell agingGO:0001302125%0.51%0.02(n.s)
regulation of metabolismGO:0019222250%6.37%0.02(n.s)
transcription, DNA-dependentGO:0006351250%6.78%0.03(n.s)
cell agingGO:0007569125%0.64%0.03(n.s)
agingGO:0007568125%0.65%0.03(n.s)
transcription initiation from RNA polymerase II promoterGO:0006367125%0.68%0.03(n.s)
cell deathGO:0008219125%0.71%0.03(n.s)
deathGO:0016265125%0.73%0.03(n.s)
transcriptionGO:0006350250%7.43%0.03(n.s)
transcription initiationGO:0006352125%0.85%0.03(n.s)
glucose metabolismGO:0006006125%1.01%0.04(n.s)
regulation of physiological processGO:0050791250%8.77%0.04(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139375%23.17%0.04(n.s)
regulation of biological processGO:0050789250%8.97%0.04(n.s)
filamentous growthGO:0030447125%1.32%0.05(n.s)
hexose metabolismGO:0019318125%1.32%0.05(n.s)
protein amino acid phosphorylationGO:0006468125%1.41%0.06(n.s)
monosaccharide metabolismGO:0005996125%1.43%0.06(n.s)
primary metabolismGO:00442384100%48.71%0.06(n.s)
growthGO:0040007125%1.72%0.07(n.s)
cellular metabolismGO:00442374100%52.12%0.07(n.s)
chromatin remodelingGO:0006338125%2.01%0.08(n.s)
metabolismGO:00081524100%52.93%0.08(n.s)
phosphorylationGO:0016310125%2.21%0.09(n.s)
alcohol metabolismGO:0006066125%2.43%0.09(n.s)
signal transductionGO:0007165125%2.59%0.1(n.s)
chromatin modificationGO:0016568125%2.77%0.11(n.s)
regulation of transcription from RNA polymerase II promoterGO:0006357125%2.8%0.11(n.s)
phosphate metabolismGO:0006796125%2.91%0.11(n.s)
phosphorus metabolismGO:0006793125%2.91%0.11(n.s)
energy derivation by oxidation of organic compoundsGO:0015980125%3.04%0.12(n.s)
cellular carbohydrate metabolismGO:0044262125%3.08%0.12(n.s)
cell communicationGO:0007154125%3.08%0.12(n.s)
DNA packagingGO:0006323125%3.14%0.12(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325125%3.14%0.12(n.s)
carbohydrate metabolismGO:0005975125%3.38%0.13(n.s)
generation of precursor metabolites and energyGO:0006091125%3.5%0.13(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001125%3.72%0.14(n.s)
response to external stimulusGO:0009605125%3.87%0.15(n.s)
chromosome organization and biogenesisGO:0051276125%3.9%0.15(n.s)
regulation of transcription, DNA-dependentGO:0006355125%4.68%0.17(n.s)
regulation of transcriptionGO:0045449125%4.96%0.18(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219125%5.24%0.19(n.s)
developmentGO:0007275125%5.73%0.21(n.s)
regulation of cellular metabolismGO:0031323125%5.98%0.22(n.s)
response to stressGO:0006950125%6.09%0.22(n.s)
protein modificationGO:0006464125%6.68%0.24(n.s)
biopolymer metabolismGO:0043283250%25.06%0.26(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
response to stimulusGO:0050896125%8.41%0.3(n.s)
regulation of cellular physiological processGO:0051244125%8.49%0.3(n.s)
regulation of cellular processGO:0050794125%8.52%0.3(n.s)
DNA metabolismGO:0006259125%8.58%0.3(n.s)
biopolymer modificationGO:0043412125%9.25%0.32(n.s)
organelle organization and biogenesisGO:0006996125%15.69%0.49(n.s)
cell organization and biogenesisGO:0016043125%17.98%0.55(n.s)
cellular protein metabolismGO:0044267125%21.7%0.62(n.s)
protein metabolismGO:0019538125%22.06%0.63(n.s)
cellular macromolecule metabolismGO:0044260125%24.52%0.68(n.s)
macromolecule metabolismGO:0043170125%26.04%0.7(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transcription cofactor activityGO:0003712250%0.56%1.8E-4(0.29)
transcription factor bindingGO:0008134250%0.6%2.12E-4(0.34)
transcription regulator activityGO:0030528375%5%4.78E-4(0.77)
AMP-activated protein kinase activityGO:0004679125%0.05%1.86E-3(n.s)
transcription corepressor activityGO:0003714125%0.25%9.88E-3(n.s)
protein bindingGO:0005515250%7.39%0.03(n.s)
general RNA polymerase II transcription factor activityGO:0016251125%0.96%0.04(n.s)
protein serine/threonine kinase activityGO:0004674125%1.08%0.04(n.s)
RNA polymerase II transcription factor activityGO:0003702125%1.89%0.07(n.s)
protein kinase activityGO:0004672125%1.97%0.08(n.s)
phosphotransferase activity, alcohol group as acceptorGO:0016773125%2.62%0.1(n.s)
kinase activityGO:0016301125%3.05%0.12(n.s)
bindingGO:0005488250%17.35%0.14(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772125%5.19%0.19(n.s)
transferase activityGO:0016740125%10.13%0.35(n.s)
catalytic activityGO:0003824125%29.21%0.75(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
SWI/SNF complexGO:0016514125%0.17%6.8E-3(n.s)
nucleusGO:00056344100%31.01%9.23E-3(n.s)
chromatin remodeling complexGO:0016585125%1.08%0.04(n.s)
lytic vacuoleGO:0000323125%2.23%0.09(n.s)
vacuole (sensu Fungi)GO:0000324125%2.23%0.09(n.s)
storage vacuoleGO:0000322125%2.23%0.09(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
vacuoleGO:0005773125%2.97%0.11(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
nucleoplasmGO:0005654125%4.86%0.18(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cellGO:00056234100%83.5%0.49(n.s)
mitochondrionGO:0005739125%15.78%0.5(n.s)
protein complexGO:0043234125%21.07%0.61(n.s)
cytoplasmGO:0005737125%55.64%0.96(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_83 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA processingGO:0006396375%5.33%5.76E-4(0.93)
mitochondrion organization and biogenesisGO:0007005250%1.47%1.26E-3(n.s)
RNA metabolismGO:0016070375%8.32%2.15E-3(n.s)
rRNA processingGO:0006364250%2.71%4.23E-3(n.s)
ribosome biogenesisGO:0007046250%3.3%6.22E-3(n.s)
ribosome biogenesis and assemblyGO:0042254250%3.9%8.64E-3(n.s)
cytoplasm organization and biogenesisGO:0007028250%3.9%8.64E-3(n.s)
rRNA metabolismGO:0016072250%3.92%8.71E-3(n.s)
organelle organization and biogenesisGO:0006996375%15.69%0.01(n.s)
mitochondrial genome maintenanceGO:0000002125%0.42%0.02(n.s)
cell organization and biogenesisGO:0016043375%17.98%0.02(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139375%23.17%0.04(n.s)
biopolymer metabolismGO:0043283375%25.06%0.05(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
primary metabolismGO:0044238375%48.71%0.29(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
cellular metabolismGO:0044237375%52.12%0.34(n.s)
metabolismGO:0008152375%52.93%0.36(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nuclease activityGO:0004518375%2.15%3.85E-5(0.06)
exonuclease activityGO:0004527250%0.51%1.51E-4(0.24)
hydrolase activityGO:00167874100%11.45%1.7E-4(0.28)
hydrolase activity, acting on ester bondsGO:0016788375%4.12%2.68E-4(0.43)
ATP-dependent peptidase activityGO:0004176125%0.03%1.24E-3(n.s)
ribonuclease MRP activityGO:0000171125%0.15%6.18E-3(n.s)
catalytic activityGO:00038244100%29.21%7.27E-3(n.s)
3'-5' exonuclease activityGO:0008408125%0.39%0.02(n.s)
ribonuclease activityGO:0004540125%1.55%0.06(n.s)
peptidase activityGO:0008233125%2.48%0.1(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:0005743250%2.43%3.41E-3(n.s)
inner membraneGO:0019866250%2.43%3.41E-3(n.s)
mitochondrial membraneGO:0005740250%3.16%5.72E-3(n.s)
ribonuclease MRP complexGO:0000172125%0.17%6.8E-3(n.s)
mitochondrionGO:0005739375%15.78%0.01(n.s)
organelle membraneGO:0031090250%8.58%0.04(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
membraneGO:0016020250%15.38%0.11(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
nucleolusGO:0005730125%4.58%0.17(n.s)
ribonucleoprotein complexGO:0030529125%7.19%0.26(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cytoplasmGO:0005737375%55.64%0.4(n.s)
intracellular non-membrane-bound organelleGO:0043232125%14.3%0.46(n.s)
non-membrane-bound organelleGO:0043228125%14.3%0.46(n.s)
cellGO:00056234100%83.5%0.49(n.s)
protein complexGO:0043234125%21.07%0.61(n.s)
nucleusGO:0005634125%31.01%0.77(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_81 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
age-dependent response to reactive oxygen species during chronological cell agingGO:0001320266.67%0.03%1.44E-7(2.33E-4)
age-dependent response to reactive oxygen speciesGO:0001315266.67%0.03%1.44E-7(2.33E-4)
response to reactive oxygen speciesGO:0000302266.67%0.09%2.16E-6(3.49E-3)
age-dependent response to oxidative stressGO:0001306266.67%0.11%3.02E-6(4.88E-3)
age-dependent general metabolic decline during chronological cell agingGO:0001323266.67%0.11%3.02E-6(4.88E-3)
age-dependent response to oxidative stress during chronological cell agingGO:0001324266.67%0.11%3.02E-6(4.88E-3)
age-dependent general metabolic declineGO:0007571266.67%0.12%4.03E-6(6.51E-3)
chronological cell agingGO:0001300266.67%0.15%6.47E-6(0.01)
cell agingGO:0007569266.67%0.64%1.18E-4(0.19)
agingGO:0007568266.67%0.65%1.23E-4(0.2)
cell deathGO:0008219266.67%0.71%1.48E-4(0.24)
deathGO:0016265266.67%0.73%1.55E-4(0.25)
response to oxidative stressGO:0006979266.67%0.79%1.83E-4(0.3)
oxygen and reactive oxygen species metabolismGO:0006800266.67%0.82%1.97E-4(0.32)
response to biotic stimulusGO:0009607266.67%1.08%3.45E-4(0.56)
superoxide metabolismGO:0006801133.33%0.02%**
intracellular copper ion transportGO:0015680133.33%0.09%2.79E-3(n.s)
copper ion homeostasisGO:0006878133.33%0.11%3.25E-3(n.s)
zinc ion homeostasisGO:0006882133.33%0.15%4.64E-3(n.s)
copper ion transportGO:0006825133.33%0.2%6.03E-3(n.s)
developmentGO:0007275266.67%5.73%9.45E-3(n.s)
response to stressGO:0006950266.67%6.09%0.01(n.s)
replicative cell agingGO:0001302133.33%0.51%0.02(n.s)
transition metal ion transportGO:0000041133.33%0.67%0.02(n.s)
response to stimulusGO:0050896266.67%8.41%0.02(n.s)
transition metal ion homeostasisGO:0046916133.33%0.73%0.02(n.s)
di-, tri-valent inorganic cation transportGO:0015674133.33%0.79%0.02(n.s)
di-, tri-valent inorganic cation homeostasisGO:0030005133.33%0.81%0.02(n.s)
metal ion transportGO:0030001133.33%0.87%0.03(n.s)
metal ion homeostasisGO:0006875133.33%0.91%0.03(n.s)
cation homeostasisGO:0030003133.33%1.35%0.04(n.s)
cation transportGO:0006812133.33%1.36%0.04(n.s)
cell ion homeostasisGO:0006873133.33%1.49%0.04(n.s)
ion homeostasisGO:0050801133.33%1.55%0.05(n.s)
ion transportGO:0006811133.33%1.64%0.05(n.s)
cell homeostasisGO:0019725133.33%1.64%0.05(n.s)
homeostasisGO:0042592133.33%1.73%0.05(n.s)
intracellular transportGO:0046907133.33%7.53%0.21(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
superoxide dismutase activityGO:0004784266.67%0.03%1.44E-7(2.33E-4)
oxidoreductase activity, acting on superoxide radicals as acceptorGO:0016721266.67%0.03%1.44E-7(2.33E-4)
superoxide dismutase copper chaperone activityGO:0016532133.33%0.02%**
manganese superoxide dismutase activityGO:0008383133.33%0.02%**
copper, zinc superoxide dismutase activityGO:0004785133.33%0.02%**
copper chaperone activityGO:0016531133.33%0.05%1.39E-3(n.s)
metallochaperone activityGO:0016530133.33%0.06%1.86E-3(n.s)
copper ion transporter activityGO:0005375133.33%0.09%2.79E-3(n.s)
oxidoreductase activityGO:0016491266.67%3.73%4.06E-3(n.s)
transition metal ion transporter activityGO:0046915133.33%0.42%0.01(n.s)
di-, tri-valent inorganic cation transporter activityGO:0015082133.33%0.54%0.02(n.s)
metal ion transporter activityGO:0046873133.33%0.59%0.02(n.s)
cation transporter activityGO:0008324133.33%1.89%0.06(n.s)
ion transporter activityGO:0015075133.33%2.21%0.06(n.s)
transporter activityGO:0005215133.33%6.64%0.19(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
mitochondrial intermembrane spaceGO:0005758133.33%0.39%0.01(n.s)
cytosolGO:0005829266.67%10.08%0.03(n.s)
mitochondrial inner membraneGO:0005743133.33%2.43%0.07(n.s)
inner membraneGO:0019866133.33%2.43%0.07(n.s)
mitochondrial matrixGO:0005759133.33%2.52%0.07(n.s)
mitochondrial membraneGO:0005740133.33%3.16%0.09(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
organelle membraneGO:0031090133.33%8.58%0.24(n.s)
membraneGO:0016020133.33%15.38%0.39(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_86 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein phosphatase type 2C activityGO:0015071150%0.09%1.86E-3(n.s)
protein serine/threonine phosphatase activityGO:0004722150%0.43%8.66E-3(n.s)
phosphoprotein phosphatase activityGO:0004721150%0.71%0.01(n.s)
phosphoric monoester hydrolase activityGO:0016791150%1.33%0.03(n.s)
phosphoric ester hydrolase activityGO:0042578150%1.44%0.03(n.s)
hydrolase activity, acting on ester bondsGO:0016788150%4.12%0.08(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_87 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial genome maintenanceGO:0000002150%0.42%8.35E-3(n.s)
mitochondrion organization and biogenesisGO:0007005150%1.47%0.03(n.s)
cellular protein catabolismGO:0044257150%2.42%0.05(n.s)
proteolysis and peptidolysisGO:0006508150%2.42%0.05(n.s)
protein catabolismGO:0030163150%2.74%0.05(n.s)
biopolymer catabolismGO:0043285150%2.93%0.06(n.s)
cellular macromolecule catabolismGO:0044265150%4.51%0.09(n.s)
macromolecule catabolismGO:0009057150%4.83%0.09(n.s)
cellular catabolismGO:0044248150%5.84%0.11(n.s)
catabolismGO:0009056150%6.16%0.12(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
X-Pro aminopeptidase activityGO:0008451150%0.03%6.2E-4(n.s)
aminopeptidase activityGO:0004177150%0.17%3.41E-3(n.s)
exopeptidase activityGO:0008238150%0.25%4.95E-3(n.s)
metalloendopeptidase activityGO:0004222150%0.31%6.19E-3(n.s)
metallopeptidase activityGO:0008237150%0.43%8.66E-3(n.s)
endopeptidase activityGO:0004175150%0.99%0.02(n.s)
peptidase activityGO:0008233150%2.48%0.05(n.s)
transporter activityGO:0005215150%6.64%0.13(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial matrixGO:0005759150%2.52%0.05(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_84 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tRNA aminoacylationGO:0043039266.67%0.46%6.24E-5(0.1)
amino acid activationGO:0043038266.67%0.46%6.24E-5(0.1)
tRNA aminoacylation for protein translationGO:0006418266.67%0.46%6.24E-5(0.1)
tRNA modificationGO:0006400266.67%1.02%3.07E-4(0.5)
arginyl-tRNA aminoacylationGO:0006420133.33%0.02%**
isoleucyl-tRNA aminoacylationGO:0006428133.33%0.02%**
tRNA metabolismGO:0006399266.67%1.6%7.48E-4(n.s)
RNA modificationGO:0009451266.67%2.42%1.71E-3(n.s)
protein biosynthesisGO:00064123100%12.16%1.79E-3(n.s)
macromolecule biosynthesisGO:00090593100%13.04%2.21E-3(n.s)
amino acid metabolismGO:0006520266.67%2.82%2.33E-3(n.s)
amino acid and derivative metabolismGO:0006519266.67%3.05%2.72E-3(n.s)
amine metabolismGO:0009308266.67%3.38%3.33E-3(n.s)
nitrogen compound metabolismGO:0006807266.67%3.66%3.9E-3(n.s)
cellular biosynthesisGO:00442493100%17.05%4.95E-3(n.s)
biosynthesisGO:00090583100%18.28%6.09E-3(n.s)
organic acid metabolismGO:0006082266.67%4.6%6.14E-3(n.s)
carboxylic acid metabolismGO:0019752266.67%4.6%6.14E-3(n.s)
cellular protein metabolismGO:00442673100%21.7%0.01(n.s)
protein metabolismGO:00195383100%22.06%0.01(n.s)
translationGO:0043037266.67%6.47%0.01(n.s)
cellular macromolecule metabolismGO:00442603100%24.52%0.01(n.s)
macromolecule metabolismGO:00431703100%26.04%0.02(n.s)
RNA metabolismGO:0016070266.67%8.32%0.02(n.s)
biopolymer modificationGO:0043412266.67%9.25%0.02(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139266.67%23.17%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
biopolymer metabolismGO:0043283266.67%25.06%0.16(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
arginine-tRNA ligase activityGO:0004814266.67%0.03%1.44E-7(2.33E-4)
ligase activity, forming carbon-oxygen bondsGO:00168753100%0.56%1.59E-7(2.57E-4)
tRNA ligase activityGO:00048123100%0.56%1.59E-7(2.57E-4)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:00168763100%0.56%1.59E-7(2.57E-4)
RNA ligase activityGO:00084523100%0.57%1.73E-7(2.8E-4)
ligase activity, forming phosphoric ester bondsGO:00168863100%0.62%2.2E-7(3.56E-4)
ligase activityGO:00168743100%1.89%6.59E-6(0.01)
isoleucine-tRNA ligase activityGO:0004822133.33%0.03%9.29E-4(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_85 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribosomal large subunit assembly and maintenanceGO:0000027150%0.6%0.01(n.s)
ribosomal subunit assemblyGO:0042257150%0.81%0.02(n.s)
ribosome assemblyGO:0042255150%0.99%0.02(n.s)
cell organization and biogenesisGO:00160432100%17.98%0.03(n.s)
external encapsulating structure organization and biogenesisGO:0045229150%2.17%0.04(n.s)
cell wall organization and biogenesisGO:0007047150%2.17%0.04(n.s)
protein complex assemblyGO:0006461150%2.26%0.04(n.s)
rRNA processingGO:0006364150%2.71%0.05(n.s)
ribosome biogenesisGO:0007046150%3.3%0.06(n.s)
cytoplasm organization and biogenesisGO:0007028150%3.9%0.08(n.s)
ribosome biogenesis and assemblyGO:0042254150%3.9%0.08(n.s)
rRNA metabolismGO:0016072150%3.92%0.08(n.s)
RNA processingGO:0006396150%5.33%0.1(n.s)
RNA metabolismGO:0016070150%8.32%0.16(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ATPase activityGO:0016887150%2.52%0.05(n.s)
nucleoside-triphosphatase activityGO:0017111150%3.42%0.07(n.s)
pyrophosphatase activityGO:0016462150%3.67%0.07(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818150%3.69%0.07(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817150%3.69%0.07(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cell wall (sensu Fungi)GO:0009277150%1.72%0.03(n.s)
external encapsulating structureGO:0030312150%1.72%0.03(n.s)
cell wallGO:0005618150%1.72%0.03(n.s)
plasma membraneGO:0005886150%3.67%0.07(n.s)
nucleoplasmGO:0005654150%4.86%0.09(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_3 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cellular component unknownGO:0008372150%15.74%0.29(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
intracellularGO:0005622150%77.03%0.95(n.s)
cellGO:0005623150%83.5%0.97(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_108 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
histidyl-tRNA aminoacylationGO:0006427125%0.02%**
peptidyl-arginine modificationGO:0018195125%0.03%1.24E-3(n.s)
biopolymer modificationGO:0043412375%9.25%2.93E-3(n.s)
RNA modificationGO:0009451250%2.42%3.37E-3(n.s)
fatty acid biosynthesisGO:0006633125%0.19%7.42E-3(n.s)
organic acid biosynthesisGO:0016053125%0.26%0.01(n.s)
carboxylic acid biosynthesisGO:0046394125%0.26%0.01(n.s)
peptidyl-amino acid modificationGO:0018193125%0.26%0.01(n.s)
organic acid metabolismGO:0006082250%4.6%0.01(n.s)
carboxylic acid metabolismGO:0019752250%4.6%0.01(n.s)
tRNA aminoacylationGO:0043039125%0.46%0.02(n.s)
amino acid activationGO:0043038125%0.46%0.02(n.s)
tRNA aminoacylation for protein translationGO:0006418125%0.46%0.02(n.s)
fatty acid metabolismGO:0006631125%0.67%0.03(n.s)
mRNA-nucleus exportGO:0006406125%0.93%0.04(n.s)
mRNA transportGO:0051028125%0.93%0.04(n.s)
RNA metabolismGO:0016070250%8.32%0.04(n.s)
tRNA modificationGO:0006400125%1.02%0.04(n.s)
RNA transportGO:0050658125%1.08%0.04(n.s)
nucleic acid transportGO:0050657125%1.08%0.04(n.s)
establishment of RNA localizationGO:0051236125%1.08%0.04(n.s)
RNA-nucleus exportGO:0006405125%1.08%0.04(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid transportGO:0015931125%1.21%0.05(n.s)
RNA localizationGO:0006403125%1.25%0.05(n.s)
nuclear exportGO:0051168125%1.29%0.05(n.s)
biopolymer metabolismGO:0043283375%25.06%0.05(n.s)
rRNA modificationGO:0000154125%1.38%0.05(n.s)
primary metabolismGO:00442384100%48.71%0.06(n.s)
nuclear transportGO:0051169125%1.53%0.06(n.s)
tRNA metabolismGO:0006399125%1.6%0.06(n.s)
nucleocytoplasmic transportGO:0006913125%1.63%0.06(n.s)
cellular metabolismGO:00442374100%52.12%0.07(n.s)
lipid biosynthesisGO:0008610125%1.92%0.07(n.s)
metabolismGO:00081524100%52.93%0.08(n.s)
amino acid metabolismGO:0006520125%2.82%0.11(n.s)
amino acid and derivative metabolismGO:0006519125%3.05%0.12(n.s)
cellular lipid metabolismGO:0044255125%3.16%0.12(n.s)
lipid metabolismGO:0006629125%3.38%0.13(n.s)
amine metabolismGO:0009308125%3.38%0.13(n.s)
cellular biosynthesisGO:0044249250%17.05%0.14(n.s)
nitrogen compound metabolismGO:0006807125%3.66%0.14(n.s)
rRNA metabolismGO:0016072125%3.92%0.15(n.s)
biosynthesisGO:0009058250%18.28%0.15(n.s)
cellular protein metabolismGO:0044267250%21.7%0.21(n.s)
protein metabolismGO:0019538250%22.06%0.21(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139250%23.17%0.23(n.s)
translationGO:0043037125%6.47%0.23(n.s)
protein modificationGO:0006464125%6.68%0.24(n.s)
cellular macromolecule metabolismGO:0044260250%24.52%0.25(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
intracellular transportGO:0046907125%7.53%0.27(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
macromolecule metabolismGO:0043170250%26.04%0.28(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
protein biosynthesisGO:0006412125%12.16%0.4(n.s)
macromolecule biosynthesisGO:0009059125%13.04%0.43(n.s)
transportGO:0006810125%14.27%0.46(n.s)
establishment of localizationGO:0051234125%14.39%0.46(n.s)
localizationGO:0051179125%14.82%0.47(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
S-adenosylmethionine-dependent methyltransferase activityGO:0008757250%0.77%3.49E-4(0.56)
acyl carrier activityGO:0000036125%0.02%**
rRNA (guanine-N1-)-methyltransferase activityGO:0008989125%0.02%**
histidine-tRNA ligase activityGO:0004821125%0.02%**
methyltransferase activityGO:0008168250%1.1%7.05E-4(n.s)
transferase activity, transferring one-carbon groupsGO:0016741250%1.13%7.46E-4(n.s)
rRNA (guanine) methyltransferase activityGO:0016435125%0.03%1.24E-3(n.s)
arginine N-methyltransferase activityGO:0016273125%0.05%1.86E-3(n.s)
protein-arginine N-methyltransferase activityGO:0016274125%0.05%1.86E-3(n.s)
rRNA methyltransferase activityGO:0008649125%0.06%2.48E-3(n.s)
N-methyltransferase activityGO:0008170125%0.2%8.03E-3(n.s)
RNA methyltransferase activityGO:0008173125%0.31%0.01(n.s)
ligase activity, forming carbon-oxygen bondsGO:0016875125%0.56%0.02(n.s)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876125%0.56%0.02(n.s)
tRNA ligase activityGO:0004812125%0.56%0.02(n.s)
RNA ligase activityGO:0008452125%0.57%0.02(n.s)
ligase activity, forming phosphoric ester bondsGO:0016886125%0.62%0.02(n.s)
transferase activityGO:0016740250%10.13%0.05(n.s)
carrier activityGO:0005386125%1.64%0.06(n.s)
ligase activityGO:0016874125%1.89%0.07(n.s)
catalytic activityGO:0003824375%29.21%0.08(n.s)
transporter activityGO:0005215125%6.64%0.24(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739375%15.78%0.01(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cytoplasmGO:0005737375%55.64%0.4(n.s)
cellGO:00056234100%83.5%0.49(n.s)
nucleusGO:0005634125%31.01%0.77(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_109 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
propionate metabolismGO:0019541266.67%0.08%1.44E-6(2.33E-3)
threonine catabolismGO:0006567133.33%0.05%1.39E-3(n.s)
threonine metabolismGO:0006566133.33%0.12%3.71E-3(n.s)
aspartate family amino acid catabolismGO:0009068133.33%0.15%4.64E-3(n.s)
organic acid metabolismGO:0006082266.67%4.6%6.14E-3(n.s)
carboxylic acid metabolismGO:0019752266.67%4.6%6.14E-3(n.s)
amino acid catabolismGO:0009063133.33%0.43%0.01(n.s)
amine catabolismGO:0009310133.33%0.48%0.01(n.s)
nitrogen compound catabolismGO:0044270133.33%0.48%0.01(n.s)
aspartate family amino acid metabolismGO:0009066133.33%0.7%0.02(n.s)
amino acid metabolismGO:0006520133.33%2.82%0.08(n.s)
amino acid and derivative metabolismGO:0006519133.33%3.05%0.09(n.s)
amine metabolismGO:0009308133.33%3.38%0.1(n.s)
nitrogen compound metabolismGO:0006807133.33%3.66%0.11(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
methylisocitrate lyase activityGO:0046421133.33%0.02%**
oxo-acid-lyase activityGO:0016833133.33%0.06%1.86E-3(n.s)
carbon-carbon lyase activityGO:0016830133.33%0.43%0.01(n.s)
lyase activityGO:0016829133.33%1.27%0.04(n.s)
molecular function unknownGO:0005554266.67%35.75%0.29(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
mitochondrial outer membraneGO:0005741133.33%0.53%0.02(n.s)
outer membraneGO:0019867133.33%0.53%0.02(n.s)
mitochondrial matrixGO:0005759133.33%2.52%0.07(n.s)
mitochondrial membraneGO:0005740133.33%3.16%0.09(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
organelle membraneGO:0031090133.33%8.58%0.24(n.s)
membraneGO:0016020133.33%15.38%0.39(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_102 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
coenzyme A transportGO:0015880150%0.02%**
coenzyme transportGO:0051182150%0.02%**
cofactor transportGO:0051181150%0.06%1.24E-3(n.s)
leucine biosynthesisGO:0009098150%0.08%1.55E-3(n.s)
leucine metabolismGO:0006551150%0.11%2.17E-3(n.s)
branched chain family amino acid biosynthesisGO:0009082150%0.2%4.02E-3(n.s)
branched chain family amino acid metabolismGO:0009081150%0.25%4.95E-3(n.s)
amino acid biosynthesisGO:0008652150%1.53%0.03(n.s)
nitrogen compound biosynthesisGO:0044271150%1.67%0.03(n.s)
amine biosynthesisGO:0009309150%1.67%0.03(n.s)
amino acid metabolismGO:0006520150%2.82%0.06(n.s)
amino acid and derivative metabolismGO:0006519150%3.05%0.06(n.s)
amine metabolismGO:0009308150%3.38%0.07(n.s)
nitrogen compound metabolismGO:0006807150%3.66%0.07(n.s)
organic acid metabolismGO:0006082150%4.6%0.09(n.s)
carboxylic acid metabolismGO:0019752150%4.6%0.09(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
coenzyme transporter activityGO:0051185150%0.02%**
coenzyme A transporter activityGO:0015228150%0.02%**
2-isopropylmalate synthase activityGO:0003852150%0.03%6.2E-4(n.s)
cofactor transporter activityGO:0051184150%0.12%2.48E-3(n.s)
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transferGO:0046912150%0.15%3.1E-3(n.s)
transferase activity, transferring acyl groupsGO:0016746150%1.43%0.03(n.s)
transporter activityGO:0005215150%6.64%0.13(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_100 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_101 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000043100%25.64%0.02(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
GTPase activityGO:0003924133.33%0.91%0.03(n.s)
nucleoside-triphosphatase activityGO:0017111133.33%3.42%0.1(n.s)
pyrophosphatase activityGO:0016462133.33%3.67%0.11(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818133.33%3.69%0.11(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817133.33%3.69%0.11(n.s)
molecular function unknownGO:0005554266.67%35.75%0.29(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_106 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
aerobic respirationGO:00090602100%1.27%1.59E-4(0.26)
cellular respirationGO:00453332100%1.35%1.8E-4(0.29)
energy derivation by oxidation of organic compoundsGO:00159802100%3.04%9.17E-4(n.s)
generation of precursor metabolites and energyGO:00060912100%3.5%1.22E-3(n.s)
negative regulation of translationGO:0016478150%0.06%1.24E-3(n.s)
regulation of translationGO:0006445150%0.45%8.96E-3(n.s)
regulation of protein biosynthesisGO:0006417150%0.46%9.27E-3(n.s)
regulation of protein metabolismGO:0051246150%0.67%0.01(n.s)
regulation of cellular biosynthesisGO:0031326150%0.71%0.01(n.s)
regulation of biosynthesisGO:0009889150%0.71%0.01(n.s)
regulation of cellular metabolismGO:0031323150%5.98%0.12(n.s)
regulation of metabolismGO:0019222150%6.37%0.12(n.s)
translationGO:0043037150%6.47%0.13(n.s)
regulation of cellular physiological processGO:0051244150%8.49%0.16(n.s)
regulation of cellular processGO:0050794150%8.52%0.16(n.s)
regulation of physiological processGO:0050791150%8.77%0.17(n.s)
regulation of biological processGO:0050789150%8.97%0.17(n.s)
protein biosynthesisGO:0006412150%12.16%0.23(n.s)
macromolecule biosynthesisGO:0009059150%13.04%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
unfolded protein bindingGO:0051082150%0.9%0.02(n.s)
protein bindingGO:0005515150%7.39%0.14(n.s)
bindingGO:0005488150%17.35%0.32(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:00057432100%2.43%5.88E-4(0.95)
inner membraneGO:00198662100%2.43%5.88E-4(0.95)
mitochondrial membraneGO:00057402100%3.16%9.94E-4(n.s)
integral to membraneGO:00160212100%3.55%1.25E-3(n.s)
intrinsic to membraneGO:00312242100%3.61%1.3E-3(n.s)
organelle membraneGO:00310902100%8.58%7.35E-3(n.s)
extrinsic to membraneGO:0019898150%0.48%9.58E-3(n.s)
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial matrixGO:0005759150%2.52%0.05(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_107 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein stabilizationGO:0050821133.33%0.02%**
protein complex assemblyGO:0006461266.67%2.26%1.5E-3(n.s)
cytochrome c oxidase complex assemblyGO:0008535133.33%0.14%4.18E-3(n.s)
inner mitochondrial membrane organization and biogenesisGO:0007007133.33%0.2%6.03E-3(n.s)
mitochondrial membrane organization and biogenesisGO:0007006133.33%0.29%8.8E-3(n.s)
membrane organization and biogenesisGO:0016044133.33%0.48%0.01(n.s)
mitochondrion organization and biogenesisGO:0007005133.33%1.47%0.04(n.s)
cellular protein metabolismGO:0044267266.67%21.7%0.12(n.s)
protein metabolismGO:0019538266.67%22.06%0.12(n.s)
cellular macromolecule metabolismGO:0044260266.67%24.52%0.15(n.s)
macromolecule metabolismGO:0043170266.67%26.04%0.17(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
organelle organization and biogenesisGO:0006996133.33%15.69%0.4(n.s)
cell organization and biogenesisGO:0016043133.33%17.98%0.45(n.s)
primary metabolismGO:0044238266.67%48.71%0.48(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein transporter activityGO:0008565266.67%0.77%1.75E-4(0.28)
protein translocase activityGO:0015450133.33%0.02%**
transporter activityGO:0005215266.67%6.64%0.01(n.s)
P-P-bond-hydrolysis-driven transporter activityGO:0015405133.33%0.45%0.01(n.s)
primary active transporter activityGO:0015399133.33%0.77%0.02(n.s)
carrier activityGO:0005386133.33%1.64%0.05(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:00057433100%2.43%1.41E-5(0.02)
inner membraneGO:00198663100%2.43%1.41E-5(0.02)
mitochondrial membraneGO:00057403100%3.16%3.11E-5(0.05)
organelle membraneGO:00310903100%8.58%6.29E-4(n.s)
membraneGO:00160203100%15.38%3.63E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
integral to membraneGO:0016021133.33%3.55%0.1(n.s)
intrinsic to membraneGO:0031224133.33%3.61%0.1(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_104 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
carboxylic acid transportGO:00469422100%0.77%5.88E-5(0.1)
organic acid transportGO:00158492100%0.79%6.12E-5(0.1)
lactate transportGO:0015727150%0.02%**
succinate transportGO:0015744150%0.02%**
fumarate transportGO:0015741150%0.02%**
dicarboxylic acid transportGO:0006835150%0.05%9.29E-4(n.s)
monocarboxylic acid transportGO:0015718150%0.12%2.48E-3(n.s)
transportGO:00068102100%14.27%0.02(n.s)
establishment of localizationGO:00512342100%14.39%0.02(n.s)
localizationGO:00511792100%14.82%0.02(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
carboxylic acid transporter activityGO:00469432100%0.74%5.41E-5(0.09)
organic acid transporter activityGO:00053422100%0.79%6.12E-5(0.1)
succinate:fumarate antiporter activityGO:0005469150%0.02%**
fumarate transporter activityGO:0015138150%0.02%**
lactate transporter activityGO:0015129150%0.02%**
succinate transporter activityGO:0015141150%0.02%**
dicarboxylic acid transporter activityGO:0005310150%0.05%9.29E-4(n.s)
antiporter activityGO:0015297150%0.14%2.79E-3(n.s)
monocarboxylic acid transporter activityGO:0008028150%0.2%4.02E-3(n.s)
transporter activityGO:00052152100%6.64%4.41E-3(n.s)
porter activityGO:0015291150%0.59%0.01(n.s)
electrochemical potential-driven transporter activityGO:0015290150%0.59%0.01(n.s)
carrier activityGO:0005386150%1.64%0.03(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
plasma membraneGO:0005886150%3.67%0.07(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_39 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
histone ubiquitinationGO:0016574133.33%0.05%1.39E-3(n.s)
glycerol catabolismGO:0019563133.33%0.05%1.39E-3(n.s)
polyol catabolismGO:0046174133.33%0.05%1.39E-3(n.s)
alcohol metabolismGO:0006066266.67%2.43%1.73E-3(n.s)
glycerol transportGO:0015793133.33%0.06%1.86E-3(n.s)
polyol transportGO:0015791133.33%0.09%2.79E-3(n.s)
galactose metabolismGO:0006012133.33%0.12%3.71E-3(n.s)
polyol metabolismGO:0019751133.33%0.12%3.71E-3(n.s)
glycerol metabolismGO:0006071133.33%0.12%3.71E-3(n.s)
histone methylationGO:0016571133.33%0.26%7.88E-3(n.s)
protein amino acid alkylationGO:0008213133.33%0.31%9.27E-3(n.s)
protein amino acid methylationGO:0006479133.33%0.31%9.27E-3(n.s)
protein monoubiquitinationGO:0006513133.33%0.34%0.01(n.s)
biopolymer methylationGO:0043414133.33%0.54%0.02(n.s)
alcohol catabolismGO:0046164133.33%0.57%0.02(n.s)
chromatin silencing at telomereGO:0006348133.33%0.67%0.02(n.s)
telomeric heterochromatin formationGO:0031509133.33%0.67%0.02(n.s)
protein ubiquitinationGO:0016567133.33%0.79%0.02(n.s)
covalent chromatin modificationGO:0016569133.33%0.91%0.03(n.s)
histone modificationGO:0016570133.33%0.91%0.03(n.s)
ubiquitin cycleGO:0006512133.33%1.07%0.03(n.s)
negative regulation of gene expression, epigeneticGO:0045814133.33%1.19%0.04(n.s)
chromatin silencingGO:0006342133.33%1.19%0.04(n.s)
gene silencingGO:0016458133.33%1.19%0.04(n.s)
heterochromatin formationGO:0031507133.33%1.19%0.04(n.s)
regulation of gene expression, epigeneticGO:0040029133.33%1.27%0.04(n.s)
chromatin assemblyGO:0031497133.33%1.27%0.04(n.s)
hexose metabolismGO:0019318133.33%1.32%0.04(n.s)
monosaccharide metabolismGO:0005996133.33%1.43%0.04(n.s)
chromatin assembly or disassemblyGO:0006333133.33%1.52%0.04(n.s)
negative regulation of transcription, DNA-dependentGO:0045892133.33%1.89%0.06(n.s)
negative regulation of transcriptionGO:0016481133.33%1.95%0.06(n.s)
chromatin remodelingGO:0006338133.33%2.01%0.06(n.s)
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045934133.33%2.11%0.06(n.s)
negative regulation of cellular metabolismGO:0031324133.33%2.29%0.07(n.s)
negative regulation of metabolismGO:0009892133.33%2.4%0.07(n.s)
negative regulation of cellular physiological processGO:0051243133.33%2.59%0.08(n.s)
negative regulation of cellular processGO:0048523133.33%2.59%0.08(n.s)
negative regulation of physiological processGO:0043118133.33%2.62%0.08(n.s)
negative regulation of biological processGO:0048519133.33%2.71%0.08(n.s)
chromatin modificationGO:0016568133.33%2.77%0.08(n.s)
cellular carbohydrate metabolismGO:0044262133.33%3.08%0.09(n.s)
DNA packagingGO:0006323133.33%3.14%0.09(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325133.33%3.14%0.09(n.s)
carbohydrate metabolismGO:0005975133.33%3.38%0.1(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001133.33%3.72%0.11(n.s)
chromosome organization and biogenesisGO:0051276133.33%3.9%0.11(n.s)
regulation of transcription, DNA-dependentGO:0006355133.33%4.68%0.13(n.s)
regulation of transcriptionGO:0045449133.33%4.96%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219133.33%5.24%0.15(n.s)
cellular macromolecule metabolismGO:0044260266.67%24.52%0.15(n.s)
developmentGO:0007275133.33%5.73%0.16(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
macromolecule metabolismGO:0043170266.67%26.04%0.17(n.s)
regulation of cellular metabolismGO:0031323133.33%5.98%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
regulation of metabolismGO:0019222133.33%6.37%0.18(n.s)
protein modificationGO:0006464133.33%6.68%0.19(n.s)
transcription, DNA-dependentGO:0006351133.33%6.78%0.19(n.s)
transcriptionGO:0006350133.33%7.43%0.21(n.s)
regulation of cellular physiological processGO:0051244133.33%8.49%0.23(n.s)
regulation of cellular processGO:0050794133.33%8.52%0.23(n.s)
DNA metabolismGO:0006259133.33%8.58%0.24(n.s)
regulation of physiological processGO:0050791133.33%8.77%0.24(n.s)
regulation of biological processGO:0050789133.33%8.97%0.25(n.s)
biopolymer modificationGO:0043412133.33%9.25%0.25(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
organelle organization and biogenesisGO:0006996133.33%15.69%0.4(n.s)
cell organization and biogenesisGO:0016043133.33%17.98%0.45(n.s)
primary metabolismGO:0044238266.67%48.71%0.48(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139133.33%23.17%0.55(n.s)
biopolymer metabolismGO:0043283133.33%25.06%0.58(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
O-acyltransferase activityGO:0008374133.33%0.25%7.42E-3(n.s)
ubiquitin-protein ligase activityGO:0004842133.33%0.57%0.02(n.s)
acid-amino acid ligase activityGO:0016881133.33%0.74%0.02(n.s)
ligase activity, forming carbon-nitrogen bondsGO:0016879133.33%1.07%0.03(n.s)
acyltransferase activityGO:0008415133.33%1.19%0.04(n.s)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747133.33%1.19%0.04(n.s)
transferase activity, transferring acyl groupsGO:0016746133.33%1.43%0.04(n.s)
ligase activityGO:0016874133.33%1.89%0.06(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
transferase activityGO:0016740133.33%10.13%0.27(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
plasma membraneGO:0005886133.33%3.67%0.11(n.s)
endoplasmic reticulumGO:0005783133.33%5.84%0.17(n.s)
membraneGO:0016020133.33%15.38%0.39(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cytoplasmGO:0005737266.67%55.64%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
nucleusGO:0005634133.33%31.01%0.67(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_38 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
FAD transportGO:0015883125%0.02%**
cofactor transportGO:0051181125%0.06%2.48E-3(n.s)
aerobic respirationGO:0009060125%1.27%0.05(n.s)
cellular respirationGO:0045333125%1.35%0.05(n.s)
energy derivation by oxidation of organic compoundsGO:0015980125%3.04%0.12(n.s)
generation of precursor metabolites and energyGO:0006091125%3.5%0.13(n.s)
biological process unknownGO:0000004250%25.64%0.27(n.s)
transportGO:0006810125%14.27%0.46(n.s)
establishment of localizationGO:0051234125%14.39%0.46(n.s)
localizationGO:0051179125%14.82%0.47(n.s)
cellular physiological processGO:0050875250%71.65%0.93(n.s)
cellular processGO:0009987250%72.29%0.93(n.s)
physiological processGO:0007582250%73.68%0.94(n.s)
cellular metabolismGO:0044237125%52.12%0.95(n.s)
metabolismGO:0008152125%52.93%0.95(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
FAD transporter activityGO:0015230125%0.02%**
chaperone regulator activityGO:0030188125%0.12%4.95E-3(n.s)
cofactor transporter activityGO:0051184125%0.12%4.95E-3(n.s)
transporter activityGO:0005215125%6.64%0.24(n.s)
molecular function unknownGO:0005554250%35.75%0.45(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057394100%15.78%6.18E-4(1)
cytoplasmGO:00057374100%55.64%0.1(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cellGO:00056234100%83.5%0.49(n.s)
nucleusGO:0005634125%31.01%0.77(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_33 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
negative regulation of transcription from RNA polymerase II promoter by pheromonesGO:0046020250%0.03%2.88E-7(4.65E-4)
negative regulation of transcription by pheromonesGO:0045996250%0.03%2.88E-7(4.65E-4)
regulation of transcription from RNA polymerase II promoter by pheromonesGO:0046019250%0.08%2.88E-6(4.65E-3)
regulation of transcription by pheromonesGO:0009373250%0.08%2.88E-6(4.65E-3)
negative regulation of transcription from RNA polymerase II promoterGO:0000122250%0.64%2.34E-4(0.38)
chromatin silencing at telomereGO:0006348250%0.67%2.58E-4(0.42)
telomeric heterochromatin formationGO:0031509250%0.67%2.58E-4(0.42)
response to pheromoneGO:0019236250%1.13%7.46E-4(n.s)
negative regulation of gene expression, epigeneticGO:0045814250%1.19%8.3E-4(n.s)
chromatin silencingGO:0006342250%1.19%8.3E-4(n.s)
gene silencingGO:0016458250%1.19%8.3E-4(n.s)
heterochromatin formationGO:0031507250%1.19%8.3E-4(n.s)
regulation of gene expression, epigeneticGO:0040029250%1.27%9.41E-4(n.s)
chromatin assemblyGO:0031497250%1.27%9.41E-4(n.s)
transcription, DNA-dependentGO:0006351375%6.78%1.18E-3(n.s)
chromatin assembly or disassemblyGO:0006333250%1.52%1.34E-3(n.s)
transcriptionGO:0006350375%7.43%1.54E-3(n.s)
nucleosome spacingGO:0016584125%0.05%1.86E-3(n.s)
negative regulation of transcription, DNA-dependentGO:0045892250%1.89%2.07E-3(n.s)
negative regulation of transcriptionGO:0016481250%1.95%2.21E-3(n.s)
response to stimulusGO:0050896375%8.41%2.22E-3(n.s)
chromatin remodelingGO:0006338250%2.01%2.35E-3(n.s)
DNA metabolismGO:0006259375%8.58%2.35E-3(n.s)
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045934250%2.11%2.57E-3(n.s)
response to chemical substanceGO:0042221250%2.18%2.76E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061394100%23.17%2.87E-3(n.s)
negative regulation of cellular metabolismGO:0031324250%2.29%3.04E-3(n.s)
negative regulation of metabolismGO:0009892250%2.4%3.33E-3(n.s)
negative regulation of cellular physiological processGO:0051243250%2.59%3.86E-3(n.s)
negative regulation of cellular processGO:0048523250%2.59%3.86E-3(n.s)
negative regulation of physiological processGO:0043118250%2.62%3.95E-3(n.s)
negative regulation of biological processGO:0048519250%2.71%4.23E-3(n.s)
chromatin modificationGO:0016568250%2.77%4.42E-3(n.s)
regulation of transcription from RNA polymerase II promoterGO:0006357250%2.8%4.52E-3(n.s)
DNA packagingGO:0006323250%3.14%5.66E-3(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325250%3.14%5.66E-3(n.s)
transcription initiation from RNA polymerase III promoterGO:0006384125%0.17%6.8E-3(n.s)
response to abiotic stimulusGO:0009628250%3.52%7.05E-3(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001250%3.72%7.86E-3(n.s)
response to external stimulusGO:0009605250%3.87%8.51E-3(n.s)
chromosome organization and biogenesisGO:0051276250%3.9%8.64E-3(n.s)
transcription from RNA polymerase II promoterGO:0006366250%4.29%0.01(n.s)
double-strand break repair via nonhomologous end-joiningGO:0006303125%0.29%0.01(n.s)
regulation of transcription, DNA-dependentGO:0006355250%4.68%0.01(n.s)
regulation of transcriptionGO:0045449250%4.96%0.01(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219250%5.24%0.02(n.s)
non-recombinational repairGO:0000726125%0.43%0.02(n.s)
developmentGO:0007275250%5.73%0.02(n.s)
regulation of cellular metabolismGO:0031323250%5.98%0.02(n.s)
regulation of metabolismGO:0019222250%6.37%0.02(n.s)
transcription from RNA polymerase III promoterGO:0006383125%0.59%0.02(n.s)
double-strand break repairGO:0006302125%0.64%0.03(n.s)
transcription initiationGO:0006352125%0.85%0.03(n.s)
regulation of cellular physiological processGO:0051244250%8.49%0.04(n.s)
regulation of cellular processGO:0050794250%8.52%0.04(n.s)
regulation of physiological processGO:0050791250%8.77%0.04(n.s)
regulation of biological processGO:0050789250%8.97%0.04(n.s)
biopolymer metabolismGO:0043283375%25.06%0.05(n.s)
primary metabolismGO:00442384100%48.71%0.06(n.s)
cellular metabolismGO:00442374100%52.12%0.07(n.s)
metabolismGO:00081524100%52.93%0.08(n.s)
DNA repairGO:0006281125%2.32%0.09(n.s)
response to DNA damage stimulusGO:0006974125%2.73%0.1(n.s)
response to endogenous stimulusGO:0009719125%2.82%0.11(n.s)
organelle organization and biogenesisGO:0006996250%15.69%0.12(n.s)
cell organization and biogenesisGO:0016043250%17.98%0.15(n.s)
response to stressGO:0006950125%6.09%0.22(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA polymerase III transcription factor activityGO:0003709125%0.15%6.18E-3(n.s)
DNA helicase activityGO:0003678125%0.43%0.02(n.s)
helicase activityGO:0004386125%1.3%0.05(n.s)
ATPase activityGO:0016887125%2.52%0.1(n.s)
nucleoside-triphosphatase activityGO:0017111125%3.42%0.13(n.s)
pyrophosphatase activityGO:0016462125%3.67%0.14(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817125%3.69%0.14(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818125%3.69%0.14(n.s)
transcription regulator activityGO:0030528125%5%0.19(n.s)
catalytic activityGO:0003824250%29.21%0.33(n.s)
hydrolase activityGO:0016787125%11.45%0.39(n.s)
molecular function unknownGO:0005554125%35.75%0.83(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
chromatin accessibility complexGO:0008623250%0.06%1.73E-6(2.79E-3)
nucleoplasmGO:0005654375%4.86%4.4E-4(0.71)
chromatin remodeling complexGO:0016585250%1.08%6.86E-4(n.s)
transcription factor TFIIIC complexGO:0000127125%0.09%3.71E-3(n.s)
nucleusGO:00056344100%31.01%9.23E-3(n.s)
protein complexGO:0043234375%21.07%0.03(n.s)
transcription factor complexGO:0005667125%1.87%0.07(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cellGO:00056234100%83.5%0.49(n.s)
mitochondrionGO:0005739125%15.78%0.5(n.s)
cytoplasmGO:0005737125%55.64%0.96(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_32 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membrane protein importGO:0045039133.33%0.14%4.18E-3(n.s)
inner mitochondrial membrane organization and biogenesisGO:0007007133.33%0.2%6.03E-3(n.s)
mitochondrial membrane organization and biogenesisGO:0007006133.33%0.29%8.8E-3(n.s)
misfolded or incompletely synthesized protein catabolismGO:0006515133.33%0.33%9.73E-3(n.s)
membrane organization and biogenesisGO:0016044133.33%0.48%0.01(n.s)
protein-mitochondrial targetingGO:0006626133.33%0.73%0.02(n.s)
protein importGO:0017038133.33%1.39%0.04(n.s)
mitochondrion organization and biogenesisGO:0007005133.33%1.47%0.04(n.s)
cellular protein catabolismGO:0044257133.33%2.42%0.07(n.s)
proteolysis and peptidolysisGO:0006508133.33%2.42%0.07(n.s)
protein catabolismGO:0030163133.33%2.74%0.08(n.s)
biopolymer catabolismGO:0043285133.33%2.93%0.09(n.s)
protein targetingGO:0006605133.33%3.42%0.1(n.s)
intracellular protein transportGO:0006886133.33%3.7%0.11(n.s)
protein transportGO:0015031133.33%3.79%0.11(n.s)
establishment of protein localizationGO:0045184133.33%3.95%0.11(n.s)
protein localizationGO:0008104133.33%4.37%0.13(n.s)
cellular macromolecule catabolismGO:0044265133.33%4.51%0.13(n.s)
macromolecule catabolismGO:0009057133.33%4.83%0.14(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
intracellular transportGO:0046907133.33%7.53%0.21(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
organelle organization and biogenesisGO:0006996133.33%15.69%0.4(n.s)
cell organization and biogenesisGO:0016043133.33%17.98%0.45(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biopolymer metabolismGO:0043283133.33%25.06%0.58(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
metalloendopeptidase activityGO:0004222133.33%0.31%9.27E-3(n.s)
metallopeptidase activityGO:0008237133.33%0.43%0.01(n.s)
protein transporter activityGO:0008565133.33%0.77%0.02(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:0008757133.33%0.77%0.02(n.s)
endopeptidase activityGO:0004175133.33%0.99%0.03(n.s)
methyltransferase activityGO:0008168133.33%1.1%0.03(n.s)
transferase activity, transferring one-carbon groupsGO:0016741133.33%1.13%0.03(n.s)
peptidase activityGO:0008233133.33%2.48%0.07(n.s)
transporter activityGO:0005215133.33%6.64%0.19(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
transferase activityGO:0016740133.33%10.13%0.27(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial membraneGO:00057403100%3.16%3.11E-5(0.05)
organelle membraneGO:00310903100%8.58%6.29E-4(n.s)
mitochondrial inner membraneGO:0005743266.67%2.43%1.73E-3(n.s)
inner membraneGO:0019866266.67%2.43%1.73E-3(n.s)
membraneGO:00160203100%15.38%3.63E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_36 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
Ras protein signal transductionGO:00072652100%0.25%5.76E-6(9.31E-3)
small GTPase mediated signal transductionGO:00072642100%0.85%7.13E-5(0.12)
intracellular signaling cascadeGO:00072422100%1.66%2.72E-4(0.44)
signal transductionGO:00071652100%2.59%6.65E-4(n.s)
cell communicationGO:00071542100%3.08%9.45E-4(n.s)
G-protein signaling, coupled to cAMP nucleotide second messengerGO:0007188150%0.06%1.24E-3(n.s)
G-protein signaling, coupled to cyclic nucleotide second messengerGO:0007187150%0.06%1.24E-3(n.s)
age-dependent response to oxidative stressGO:0001306150%0.11%2.17E-3(n.s)
age-dependent general metabolic decline during chronological cell agingGO:0001323150%0.11%2.17E-3(n.s)
age-dependent response to oxidative stress during chronological cell agingGO:0001324150%0.11%2.17E-3(n.s)
cAMP-mediated signalingGO:0019933150%0.12%2.48E-3(n.s)
age-dependent general metabolic declineGO:0007571150%0.12%2.48E-3(n.s)
cyclic-nucleotide-mediated signalingGO:0019935150%0.12%2.48E-3(n.s)
chronological cell agingGO:0001300150%0.15%3.1E-3(n.s)
G-protein coupled receptor protein signaling pathwayGO:0007186150%0.42%8.35E-3(n.s)
second-messenger-mediated signalingGO:0019932150%0.43%8.66E-3(n.s)
cell surface receptor linked signal transductionGO:0007166150%0.62%0.01(n.s)
cell agingGO:0007569150%0.64%0.01(n.s)
agingGO:0007568150%0.65%0.01(n.s)
cell deathGO:0008219150%0.71%0.01(n.s)
deathGO:0016265150%0.73%0.01(n.s)
response to oxidative stressGO:0006979150%0.79%0.02(n.s)
oxygen and reactive oxygen species metabolismGO:0006800150%0.82%0.02(n.s)
response to biotic stimulusGO:0009607150%1.08%0.02(n.s)
M phase of meiotic cell cycleGO:0051327150%2%0.04(n.s)
meiotic cell cycleGO:0051321150%2%0.04(n.s)
meiosisGO:0007126150%2%0.04(n.s)
regulation of progression through cell cycleGO:0000074150%2.14%0.04(n.s)
M phaseGO:0000279150%3.98%0.08(n.s)
developmentGO:0007275150%5.73%0.11(n.s)
response to stressGO:0006950150%6.09%0.12(n.s)
cell cycleGO:0007049150%6.12%0.12(n.s)
response to stimulusGO:0050896150%8.41%0.16(n.s)
regulation of cellular physiological processGO:0051244150%8.49%0.16(n.s)
regulation of cellular processGO:0050794150%8.52%0.16(n.s)
regulation of physiological processGO:0050791150%8.77%0.17(n.s)
regulation of biological processGO:0050789150%8.97%0.17(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
phosphorus-oxygen lyase activityGO:0016849150%0.02%**
adenylate cyclase activityGO:0004016150%0.02%**
cyclase activityGO:0009975150%0.03%6.2E-4(n.s)
Ras GTPase activator activityGO:0005099150%0.05%9.29E-4(n.s)
GTPase activator activityGO:0005096150%0.48%9.58E-3(n.s)
small GTPase regulator activityGO:0005083150%0.88%0.02(n.s)
enzyme activator activityGO:0008047150%0.91%0.02(n.s)
GTPase regulator activityGO:0030695150%1.04%0.02(n.s)
lyase activityGO:0016829150%1.27%0.03(n.s)
enzyme regulator activityGO:0030234150%2.54%0.05(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
plasma membraneGO:0005886150%3.67%0.07(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_34 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
terpene biosynthesisGO:0046246125%0.03%1.24E-3(n.s)
terpenoid metabolismGO:0006721125%0.03%1.24E-3(n.s)
terpene metabolismGO:0042214125%0.03%1.24E-3(n.s)
terpenoid biosynthesisGO:0016114125%0.03%1.24E-3(n.s)
regulation of exocytosisGO:0017157125%0.03%1.24E-3(n.s)
polyisoprenoid metabolismGO:0016096125%0.03%1.24E-3(n.s)
polyisoprenoid biosynthesisGO:0009241125%0.03%1.24E-3(n.s)
isoprenoid biosynthesisGO:0008299125%0.09%3.71E-3(n.s)
isoprenoid metabolismGO:0006720125%0.09%3.71E-3(n.s)
phosphoinositide dephosphorylationGO:0046856125%0.11%4.33E-3(n.s)
phospholipid dephosphorylationGO:0046839125%0.11%4.33E-3(n.s)
regulation of transportGO:0051049125%0.11%4.33E-3(n.s)
cellular lipid metabolismGO:0044255250%3.16%5.72E-3(n.s)
lipid metabolismGO:0006629250%3.38%6.51E-3(n.s)
lipid modificationGO:0030258125%0.19%7.42E-3(n.s)
inositol lipid-mediated signalingGO:0048017125%0.2%8.03E-3(n.s)
adaptation to pheromone during conjugation with cellular fusionGO:0000754125%0.2%8.03E-3(n.s)
phosphoinositide-mediated signalingGO:0048015125%0.2%8.03E-3(n.s)
fermentationGO:0006113125%0.25%9.88E-3(n.s)
secondary metabolismGO:0019748125%0.28%0.01(n.s)
second-messenger-mediated signalingGO:0019932125%0.43%0.02(n.s)
dephosphorylationGO:0016311125%0.54%0.02(n.s)
exocytosisGO:0006887125%0.56%0.02(n.s)
response to pheromoneGO:0019236125%1.13%0.04(n.s)
cell ion homeostasisGO:0006873125%1.49%0.06(n.s)
ion homeostasisGO:0050801125%1.55%0.06(n.s)
sexual reproductionGO:0019953125%1.63%0.06(n.s)
conjugationGO:0000746125%1.63%0.06(n.s)
conjugation with cellular fusionGO:0000747125%1.63%0.06(n.s)
cell homeostasisGO:0019725125%1.64%0.06(n.s)
intracellular signaling cascadeGO:0007242125%1.66%0.06(n.s)
homeostasisGO:0042592125%1.73%0.07(n.s)
lipid biosynthesisGO:0008610125%1.92%0.07(n.s)
cell wall organization and biogenesisGO:0007047125%2.17%0.08(n.s)
external encapsulating structure organization and biogenesisGO:0045229125%2.17%0.08(n.s)
response to chemical substanceGO:0042221125%2.18%0.08(n.s)
signal transductionGO:0007165125%2.59%0.1(n.s)
phosphate metabolismGO:0006796125%2.91%0.11(n.s)
phosphorus metabolismGO:0006793125%2.91%0.11(n.s)
reproductive cellular physiological processGO:0048610125%2.93%0.11(n.s)
reproductive physiological processGO:0050876125%2.93%0.11(n.s)
energy derivation by oxidation of organic compoundsGO:0015980125%3.04%0.12(n.s)
cell communicationGO:0007154125%3.08%0.12(n.s)
secretory pathwayGO:0045045125%3.13%0.12(n.s)
secretionGO:0046903125%3.24%0.12(n.s)
generation of precursor metabolites and energyGO:0006091125%3.5%0.13(n.s)
response to abiotic stimulusGO:0009628125%3.52%0.13(n.s)
response to external stimulusGO:0009605125%3.87%0.15(n.s)
reproductionGO:0000003125%3.92%0.15(n.s)
vesicle-mediated transportGO:0016192125%4.34%0.16(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
response to stimulusGO:0050896125%8.41%0.3(n.s)
regulation of cellular physiological processGO:0051244125%8.49%0.3(n.s)
regulation of cellular processGO:0050794125%8.52%0.3(n.s)
regulation of physiological processGO:0050791125%8.77%0.31(n.s)
regulation of biological processGO:0050789125%8.97%0.31(n.s)
biopolymer modificationGO:0043412125%9.25%0.32(n.s)
cellular metabolismGO:0044237375%52.12%0.34(n.s)
metabolismGO:0008152375%52.93%0.36(n.s)
transportGO:0006810125%14.27%0.46(n.s)
establishment of localizationGO:0051234125%14.39%0.46(n.s)
localizationGO:0051179125%14.82%0.47(n.s)
cellular biosynthesisGO:0044249125%17.05%0.53(n.s)
cell organization and biogenesisGO:0016043125%17.98%0.55(n.s)
biosynthesisGO:0009058125%18.28%0.55(n.s)
primary metabolismGO:0044238250%48.71%0.67(n.s)
biopolymer metabolismGO:0043283125%25.06%0.68(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
farnesyltranstransferase activityGO:0004311125%0.05%1.86E-3(n.s)
calcium ion bindingGO:0005509125%0.06%2.48E-3(n.s)
inositol or phosphatidylinositol phosphatase activityGO:0004437125%0.14%5.57E-3(n.s)
cation bindingGO:0043169125%0.19%7.42E-3(n.s)
prenyltransferase activityGO:0004659125%0.2%8.03E-3(n.s)
metal ion bindingGO:0046872125%0.25%9.88E-3(n.s)
ion bindingGO:0043167125%0.25%9.88E-3(n.s)
transferase activity, transferring alkyl or aryl (other than methyl) groupsGO:0016765125%0.53%0.02(n.s)
phosphoric monoester hydrolase activityGO:0016791125%1.33%0.05(n.s)
phosphoric ester hydrolase activityGO:0042578125%1.44%0.06(n.s)
hydrolase activity, acting on ester bondsGO:0016788125%4.12%0.15(n.s)
catalytic activityGO:0003824250%29.21%0.33(n.s)
transferase activityGO:0016740125%10.13%0.35(n.s)
hydrolase activityGO:0016787125%11.45%0.39(n.s)
bindingGO:0005488125%17.35%0.53(n.s)
molecular function unknownGO:0005554125%35.75%0.83(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
calcineurin complexGO:0005955125%0.05%1.86E-3(n.s)
integral to Golgi membraneGO:0030173125%0.14%5.57E-3(n.s)
intrinsic to Golgi membraneGO:0031228125%0.14%5.57E-3(n.s)
protein serine/threonine phosphatase complexGO:0008287125%0.25%9.88E-3(n.s)
integral to endoplasmic reticulum membraneGO:0030176125%0.34%0.01(n.s)
intrinsic to endoplasmic reticulum membraneGO:0031227125%0.34%0.01(n.s)
mitochondrionGO:0005739375%15.78%0.01(n.s)
Golgi membraneGO:0000139125%0.39%0.02(n.s)
integral to organelle membraneGO:0031301125%0.54%0.02(n.s)
intrinsic to organelle membraneGO:0031300125%0.57%0.02(n.s)
unlocalized protein complexGO:0005941125%0.57%0.02(n.s)
endoplasmic reticulum membraneGO:0005789125%1.78%0.07(n.s)
nuclear envelope-endoplasmic reticulum networkGO:0042175125%1.95%0.08(n.s)
Golgi apparatusGO:0005794125%2.01%0.08(n.s)
cytoplasmGO:00057374100%55.64%0.1(n.s)
integral to membraneGO:0016021125%3.55%0.13(n.s)
intrinsic to membraneGO:0031224125%3.61%0.14(n.s)
endomembrane systemGO:0012505125%3.7%0.14(n.s)
endoplasmic reticulumGO:0005783125%5.84%0.21(n.s)
organelle membraneGO:0031090125%8.58%0.3(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
intracellular membrane-bound organelleGO:0043231375%55.65%0.4(n.s)
membrane-bound organelleGO:0043227375%55.65%0.4(n.s)
organelleGO:0043226375%60.56%0.48(n.s)
intracellular organelleGO:0043229375%60.56%0.48(n.s)
cellGO:00056234100%83.5%0.49(n.s)
membraneGO:0016020125%15.38%0.49(n.s)
protein complexGO:0043234125%21.07%0.61(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_60 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mRNA cleavageGO:0006379266.67%0.23%1.51E-5(0.02)
mRNA polyadenylylationGO:0006378266.67%0.28%2.2E-5(0.04)
mRNA 3'-end processingGO:0031124266.67%0.31%2.73E-5(0.04)
RNA 3'-end processingGO:0031123266.67%0.33%3.02E-5(0.05)
mRNA processingGO:0006397266.67%2.03%1.21E-3(n.s)
mRNA metabolismGO:0016071266.67%2.85%2.38E-3(n.s)
RNA processingGO:0006396266.67%5.33%8.19E-3(n.s)
RNA metabolismGO:0016070266.67%8.32%0.02(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139266.67%23.17%0.14(n.s)
biopolymer metabolismGO:0043283266.67%25.06%0.16(n.s)
primary metabolismGO:0044238266.67%48.71%0.48(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein heterodimerization activityGO:0046982133.33%0.03%9.29E-4(n.s)
protein dimerization activityGO:0046983133.33%0.03%9.29E-4(n.s)
bindingGO:0005488266.67%17.35%0.08(n.s)
RNA bindingGO:0003723133.33%5.96%0.17(n.s)
protein bindingGO:0005515133.33%7.39%0.21(n.s)
nucleic acid bindingGO:0003676133.33%9.87%0.27(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mRNA cleavage factor complexGO:0005849266.67%0.31%2.73E-5(0.04)
nucleoplasmGO:0005654266.67%4.86%6.85E-3(n.s)
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
protein complexGO:0043234266.67%21.07%0.11(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
nucleusGO:0005634266.67%31.01%0.23(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_63 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytochrome c oxidase complex assemblyGO:0008535133.33%0.14%4.18E-3(n.s)
mitochondrial transportGO:0006839133.33%0.17%5.1E-3(n.s)
protein processingGO:0016485133.33%0.51%0.02(n.s)
aerobic respirationGO:0009060133.33%1.27%0.04(n.s)
cellular respirationGO:0045333133.33%1.35%0.04(n.s)
protein complex assemblyGO:0006461133.33%2.26%0.07(n.s)
energy derivation by oxidation of organic compoundsGO:0015980133.33%3.04%0.09(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
protein modificationGO:0006464133.33%6.68%0.19(n.s)
intracellular transportGO:0046907133.33%7.53%0.21(n.s)
biopolymer modificationGO:0043412133.33%9.25%0.25(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biopolymer metabolismGO:0043283133.33%25.06%0.58(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
intracellular transporter activityGO:0005478133.33%0.46%0.01(n.s)
organic acid transporter activityGO:0005342133.33%0.79%0.02(n.s)
unfolded protein bindingGO:0051082133.33%0.9%0.03(n.s)
transporter activityGO:0005215133.33%6.64%0.19(n.s)
protein bindingGO:0005515133.33%7.39%0.21(n.s)
bindingGO:0005488133.33%17.35%0.44(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:0005743266.67%2.43%1.73E-3(n.s)
inner membraneGO:0019866266.67%2.43%1.73E-3(n.s)
mitochondrial membraneGO:0005740266.67%3.16%2.92E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
organelle membraneGO:0031090266.67%8.58%0.02(n.s)
membraneGO:0016020266.67%15.38%0.06(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_65 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA metabolismGO:0016070266.67%8.32%0.02(n.s)
translational initiationGO:0006413133.33%0.74%0.02(n.s)
tRNA modificationGO:0006400133.33%1.02%0.03(n.s)
tRNA metabolismGO:0006399133.33%1.6%0.05(n.s)
RNA modificationGO:0009451133.33%2.42%0.07(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139266.67%23.17%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
RNA processingGO:0006396133.33%5.33%0.15(n.s)
biopolymer metabolismGO:0043283266.67%25.06%0.16(n.s)
translationGO:0043037133.33%6.47%0.18(n.s)
biopolymer modificationGO:0043412133.33%9.25%0.25(n.s)
protein biosynthesisGO:0006412133.33%12.16%0.32(n.s)
macromolecule biosynthesisGO:0009059133.33%13.04%0.34(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular biosynthesisGO:0044249133.33%17.05%0.43(n.s)
biosynthesisGO:0009058133.33%18.28%0.45(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
pseudouridylate synthase activityGO:0004730266.67%0.09%2.16E-6(3.49E-3)
hydro-lyase activityGO:0016836266.67%0.43%5.43E-5(0.09)
carbon-oxygen lyase activityGO:0016835266.67%0.56%9.04E-5(0.15)
lyase activityGO:0016829266.67%1.27%4.74E-4(0.77)
translation initiation factor activityGO:0003743133.33%0.46%0.01(n.s)
translation factor activity, nucleic acid bindingGO:0008135133.33%0.73%0.02(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
translation regulator activityGO:0045182133.33%0.9%0.03(n.s)
GTPase activityGO:0003924133.33%0.91%0.03(n.s)
nucleoside-triphosphatase activityGO:0017111133.33%3.42%0.1(n.s)
pyrophosphatase activityGO:0016462133.33%3.67%0.11(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817133.33%3.69%0.11(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818133.33%3.69%0.11(n.s)
RNA bindingGO:0003723133.33%5.96%0.17(n.s)
nucleic acid bindingGO:0003676133.33%9.87%0.27(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
bindingGO:0005488133.33%17.35%0.44(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
nucleusGO:0005634266.67%31.01%0.23(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_67 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
translational elongationGO:00064143100%4.83%1.12E-4(0.18)
translationGO:00430373100%6.47%2.7E-4(0.44)
protein biosynthesisGO:00064123100%12.16%1.79E-3(n.s)
macromolecule biosynthesisGO:00090593100%13.04%2.21E-3(n.s)
cellular biosynthesisGO:00442493100%17.05%4.95E-3(n.s)
biosynthesisGO:00090583100%18.28%6.09E-3(n.s)
cellular protein metabolismGO:00442673100%21.7%0.01(n.s)
protein metabolismGO:00195383100%22.06%0.01(n.s)
cellular macromolecule metabolismGO:00442603100%24.52%0.01(n.s)
macromolecule metabolismGO:00431703100%26.04%0.02(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
translation elongation factor activityGO:00037463100%0.19%4.91E-9(7.93E-6)
translation factor activity, nucleic acid bindingGO:00081353100%0.73%3.62E-7(5.85E-4)
translation regulator activityGO:00451823100%0.9%6.88E-7(1.11E-3)
nucleic acid bindingGO:00036763100%9.87%9.56E-4(n.s)
bindingGO:00054883100%17.35%5.21E-3(n.s)
GTPase activityGO:0003924133.33%0.91%0.03(n.s)
nucleoside-triphosphatase activityGO:0017111133.33%3.42%0.1(n.s)
pyrophosphatase activityGO:0016462133.33%3.67%0.11(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817133.33%3.69%0.11(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818133.33%3.69%0.11(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
mitochondrial matrixGO:0005759133.33%2.52%0.07(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_68 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
proteolysis and peptidolysisGO:0006508150%2.42%0.05(n.s)
cellular protein catabolismGO:0044257150%2.42%0.05(n.s)
protein catabolismGO:0030163150%2.74%0.05(n.s)
biopolymer catabolismGO:0043285150%2.93%0.06(n.s)
cellular macromolecule catabolismGO:0044265150%4.51%0.09(n.s)
macromolecule catabolismGO:0009057150%4.83%0.09(n.s)
cellular catabolismGO:0044248150%5.84%0.11(n.s)
catabolismGO:0009056150%6.16%0.12(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
metalloendopeptidase activityGO:0004222150%0.31%6.19E-3(n.s)
metallopeptidase activityGO:0008237150%0.43%8.66E-3(n.s)
endopeptidase activityGO:0004175150%0.99%0.02(n.s)
peptidase activityGO:0008233150%2.48%0.05(n.s)
transporter activityGO:0005215150%6.64%0.13(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_2 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_162 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tRNA splicingGO:00063882100%0.22%4.37E-6(7.06E-3)
RNA splicing, via endonucleolytic cleavage and ligationGO:00003942100%0.22%4.37E-6(7.06E-3)
tRNA processingGO:00080332100%0.53%2.69E-5(0.04)
tRNA metabolismGO:00063992100%1.6%2.52E-4(0.41)
RNA splicingGO:00083802100%1.95%3.78E-4(0.61)
RNA processingGO:00063962100%5.33%2.83E-3(n.s)
RNA metabolismGO:00160702100%8.32%6.91E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061392100%23.17%0.05(n.s)
biopolymer metabolismGO:00432832100%25.06%0.06(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tRNA-intron endonuclease activityGO:00002132100%0.06%2.88E-7(4.65E-4)
endoribonuclease activity, producing 3'-phosphomonoestersGO:00168922100%0.06%2.88E-7(4.65E-4)
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoestersGO:00168942100%0.08%4.8E-7(7.76E-4)
tRNA-specific ribonuclease activityGO:00045492100%0.25%5.76E-6(9.31E-3)
endoribonuclease activityGO:00045212100%0.42%1.68E-5(0.03)
endonuclease activityGO:00045192100%0.88%7.66E-5(0.12)
ribonuclease activityGO:00045402100%1.55%2.38E-4(0.38)
nuclease activityGO:00045182100%2.15%4.6E-4(0.74)
hydrolase activity, acting on ester bondsGO:00167882100%4.12%1.69E-3(n.s)
hydrolase activityGO:00167872100%11.45%0.01(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tRNA-intron endonuclease complexGO:00002142100%0.06%2.88E-7(4.65E-4)
nuclear inner membraneGO:00056372100%0.09%7.2E-7(1.16E-3)
mitochondrial outer membraneGO:00057412100%0.53%2.69E-5(0.04)
outer membraneGO:00198672100%0.53%2.69E-5(0.04)
nuclear membraneGO:00056352100%1.53%2.33E-4(0.38)
mitochondrial membraneGO:00057402100%3.16%9.94E-4(n.s)
endomembrane systemGO:00125052100%3.7%1.36E-3(n.s)
organelle membraneGO:00310902100%8.58%7.35E-3(n.s)
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
protein complexGO:00432342100%21.07%0.04(n.s)
nucleusGO:00056342100%31.01%0.1(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_91 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein amino acid O-linked glycosylationGO:0006493150%0.25%4.95E-3(n.s)
GPI anchor biosynthesisGO:0006506150%0.36%7.11E-3(n.s)
GPI anchor metabolismGO:0006505150%0.37%7.42E-3(n.s)
phosphoinositide biosynthesisGO:0046489150%0.37%7.42E-3(n.s)
phosphoinositide metabolismGO:0030384150%0.48%9.58E-3(n.s)
glycerophospholipid biosynthesisGO:0046474150%0.53%0.01(n.s)
lipoprotein metabolismGO:0042157150%0.56%0.01(n.s)
lipoprotein biosynthesisGO:0042158150%0.56%0.01(n.s)
protein lipidationGO:0006497150%0.56%0.01(n.s)
protein amino acid N-linked glycosylationGO:0006487150%0.67%0.01(n.s)
glycerophospholipid metabolismGO:0006650150%0.68%0.01(n.s)
phospholipid biosynthesisGO:0008654150%0.81%0.02(n.s)
biopolymer glycosylationGO:0043413150%1.02%0.02(n.s)
protein amino acid glycosylationGO:0006486150%1.02%0.02(n.s)
glycoprotein biosynthesisGO:0009101150%1.1%0.02(n.s)
membrane lipid biosynthesisGO:0046467150%1.1%0.02(n.s)
glycoprotein metabolismGO:0009100150%1.12%0.02(n.s)
phospholipid metabolismGO:0006644150%1.19%0.02(n.s)
membrane lipid metabolismGO:0006643150%1.61%0.03(n.s)
lipid biosynthesisGO:0008610150%1.92%0.04(n.s)
cellular lipid metabolismGO:0044255150%3.16%0.06(n.s)
lipid metabolismGO:0006629150%3.38%0.07(n.s)
protein modificationGO:0006464150%6.68%0.13(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
protein biosynthesisGO:0006412150%12.16%0.23(n.s)
macromolecule biosynthesisGO:0009059150%13.04%0.24(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
dolichyl-phosphate beta-D-mannosyltransferase activityGO:0004582150%0.02%**
mannosyltransferase activityGO:0000030150%0.62%0.01(n.s)
transferase activity, transferring hexosyl groupsGO:0016758150%1.12%0.02(n.s)
transferase activity, transferring glycosyl groupsGO:0016757150%1.41%0.03(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
endoplasmic reticulumGO:00057832100%5.84%3.4E-3(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
nuclear envelope-endoplasmic reticulum networkGO:0042175150%1.95%0.04(n.s)
endomembrane systemGO:0012505150%3.7%0.07(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_90 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial intermembrane space protein importGO:0045041150%0.09%1.86E-3(n.s)
signal peptide processingGO:0006465150%0.11%2.17E-3(n.s)
peptide metabolismGO:0006518150%0.12%2.48E-3(n.s)
protein processingGO:0016485150%0.51%0.01(n.s)
protein-mitochondrial targetingGO:0006626150%0.73%0.01(n.s)
protein importGO:0017038150%1.39%0.03(n.s)
mitochondrion organization and biogenesisGO:0007005150%1.47%0.03(n.s)
protein targetingGO:0006605150%3.42%0.07(n.s)
intracellular protein transportGO:0006886150%3.7%0.07(n.s)
protein transportGO:0015031150%3.79%0.07(n.s)
establishment of protein localizationGO:0045184150%3.95%0.08(n.s)
protein localizationGO:0008104150%4.37%0.09(n.s)
protein modificationGO:0006464150%6.68%0.13(n.s)
intracellular transportGO:0046907150%7.53%0.14(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
peptidase activityGO:0008233150%2.48%0.05(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_93 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrion organization and biogenesisGO:0007005266.67%1.47%6.37E-4(n.s)
ion transportGO:0006811266.67%1.64%7.93E-4(n.s)
cytochrome c-heme linkageGO:0018063133.33%0.05%1.39E-3(n.s)
protein-heme linkageGO:0017003133.33%0.05%1.39E-3(n.s)
protein-tetrapyrrole linkageGO:0017006133.33%0.05%1.39E-3(n.s)
cytochrome complex assemblyGO:0017004133.33%0.08%2.32E-3(n.s)
mitochondrial intermembrane space protein importGO:0045041133.33%0.09%2.79E-3(n.s)
transportGO:00068103100%14.27%2.9E-3(n.s)
establishment of localizationGO:00512343100%14.39%2.97E-3(n.s)
localizationGO:00511793100%14.82%3.25E-3(n.s)
mitochondrial membrane organization and biogenesisGO:0007006133.33%0.29%8.8E-3(n.s)
membrane organization and biogenesisGO:0016044133.33%0.48%0.01(n.s)
protein-mitochondrial targetingGO:0006626133.33%0.73%0.02(n.s)
aerobic respirationGO:0009060133.33%1.27%0.04(n.s)
cellular respirationGO:0045333133.33%1.35%0.04(n.s)
protein importGO:0017038133.33%1.39%0.04(n.s)
organelle organization and biogenesisGO:0006996266.67%15.69%0.07(n.s)
protein complex assemblyGO:0006461133.33%2.26%0.07(n.s)
cell organization and biogenesisGO:0016043266.67%17.98%0.09(n.s)
energy derivation by oxidation of organic compoundsGO:0015980133.33%3.04%0.09(n.s)
protein targetingGO:0006605133.33%3.42%0.1(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
intracellular protein transportGO:0006886133.33%3.7%0.11(n.s)
protein transportGO:0015031133.33%3.79%0.11(n.s)
establishment of protein localizationGO:0045184133.33%3.95%0.11(n.s)
protein localizationGO:0008104133.33%4.37%0.13(n.s)
protein modificationGO:0006464133.33%6.68%0.19(n.s)
intracellular transportGO:0046907133.33%7.53%0.21(n.s)
biopolymer modificationGO:0043412133.33%9.25%0.25(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biopolymer metabolismGO:0043283133.33%25.06%0.58(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
voltage-gated ion-selective channel activityGO:0008308266.67%0.03%1.44E-7(2.33E-4)
anion channel activityGO:0005253266.67%0.05%4.32E-7(6.98E-4)
ion channel activityGO:0005216266.67%0.09%2.16E-6(3.49E-3)
channel or pore class transporter activityGO:0015267266.67%0.15%6.47E-6(0.01)
alpha-type channel activityGO:0015268266.67%0.15%6.47E-6(0.01)
anion transporter activityGO:0008509266.67%0.28%2.2E-5(0.04)
ion transporter activityGO:0015075266.67%2.21%1.44E-3(n.s)
transporter activityGO:0005215266.67%6.64%0.01(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial outer membraneGO:0005741266.67%0.53%8.05E-5(0.13)
outer membraneGO:0019867266.67%0.53%8.05E-5(0.13)
mitochondrial membraneGO:0005740266.67%3.16%2.92E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
organelle membraneGO:0031090266.67%8.58%0.02(n.s)
membraneGO:0016020266.67%15.38%0.06(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_92 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA ligationGO:0006266150%0.02%**
DNA repairGO:00062812100%2.32%5.36E-4(0.87)
response to DNA damage stimulusGO:00069742100%2.73%7.39E-4(n.s)
response to endogenous stimulusGO:00097192100%2.82%7.9E-4(n.s)
base-excision repairGO:0006284150%0.15%3.1E-3(n.s)
response to stressGO:00069502100%6.09%3.7E-3(n.s)
lagging strand elongationGO:0006273150%0.31%6.19E-3(n.s)
response to stimulusGO:00508962100%8.41%7.06E-3(n.s)
DNA metabolismGO:00062592100%8.58%7.35E-3(n.s)
DNA strand elongationGO:0006271150%0.46%9.27E-3(n.s)
nucleotide-excision repairGO:0006289150%0.48%9.58E-3(n.s)
DNA-dependent DNA replicationGO:0006261150%1.24%0.02(n.s)
DNA replicationGO:0006260150%1.6%0.03(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061392100%23.17%0.05(n.s)
DNA recombinationGO:0006310150%2.91%0.06(n.s)
biopolymer metabolismGO:00432832100%25.06%0.06(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
uracil DNA N-glycosylase activityGO:0004844150%0.02%**
DNA ligase activityGO:0003909150%0.03%6.2E-4(n.s)
DNA ligase (ATP) activityGO:0003910150%0.03%6.2E-4(n.s)
DNA N-glycosylase activityGO:0019104150%0.09%1.86E-3(n.s)
hydrolase activity, hydrolyzing N-glycosyl compoundsGO:0016799150%0.11%2.17E-3(n.s)
ligase activity, forming phosphoric ester bondsGO:0016886150%0.62%0.01(n.s)
hydrolase activity, acting on glycosyl bondsGO:0016798150%0.93%0.02(n.s)
ligase activityGO:0016874150%1.89%0.04(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
replication forkGO:0005657150%0.6%0.01(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
chromosomeGO:0005694150%3.16%0.06(n.s)
nucleusGO:00056342100%31.01%0.1(n.s)
intracellular non-membrane-bound organelleGO:0043232150%14.3%0.27(n.s)
non-membrane-bound organelleGO:0043228150%14.3%0.27(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_94 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
secretory pathwayGO:00450453100%3.13%3.02E-5(0.05)
secretionGO:00469033100%3.24%3.35E-5(0.05)
exocytosisGO:0006887266.67%0.56%9.04E-5(0.15)
transportGO:00068103100%14.27%2.9E-3(n.s)
establishment of localizationGO:00512343100%14.39%2.97E-3(n.s)
localizationGO:00511793100%14.82%3.25E-3(n.s)
vesicle-mediated transportGO:0016192266.67%4.34%5.46E-3(n.s)
Golgi to plasma membrane transportGO:0006893133.33%0.31%9.27E-3(n.s)
vesicle fusionGO:0006906133.33%0.46%0.01(n.s)
bipolar bud site selectionGO:0007121133.33%0.5%0.01(n.s)
post-Golgi transportGO:0006892133.33%0.79%0.02(n.s)
small GTPase mediated signal transductionGO:0007264133.33%0.85%0.03(n.s)
membrane fusionGO:0006944133.33%0.88%0.03(n.s)
bud site selectionGO:0000282133.33%1.01%0.03(n.s)
cytokinesis, site selectionGO:0007105133.33%1.01%0.03(n.s)
cell buddingGO:0007114133.33%1.19%0.04(n.s)
asexual reproductionGO:0019954133.33%1.19%0.04(n.s)
cytokinesisGO:0000910133.33%1.5%0.04(n.s)
establishment of cell polarity (sensu Fungi)GO:0030468133.33%1.6%0.05(n.s)
establishment of cell polarityGO:0030010133.33%1.6%0.05(n.s)
establishment and/or maintenance of cell polarity (sensu Fungi)GO:0030467133.33%1.66%0.05(n.s)
establishment and/or maintenance of cell polarityGO:0007163133.33%1.66%0.05(n.s)
intracellular signaling cascadeGO:0007242133.33%1.66%0.05(n.s)
cell divisionGO:0051301133.33%1.91%0.06(n.s)
Golgi vesicle transportGO:0048193133.33%2.18%0.06(n.s)
cellular morphogenesisGO:0000902133.33%2.23%0.07(n.s)
morphogenesisGO:0009653133.33%2.23%0.07(n.s)
signal transductionGO:0007165133.33%2.59%0.08(n.s)
cell communicationGO:0007154133.33%3.08%0.09(n.s)
reproductionGO:0000003133.33%3.92%0.11(n.s)
cytoskeleton organization and biogenesisGO:0007010133.33%4.48%0.13(n.s)
developmentGO:0007275133.33%5.73%0.16(n.s)
intracellular transportGO:0046907133.33%7.53%0.21(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
organelle organization and biogenesisGO:0006996133.33%15.69%0.4(n.s)
cell organization and biogenesisGO:0016043133.33%17.98%0.45(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
guanyl-nucleotide exchange factor activityGO:0005085266.67%0.4%4.67E-5(0.08)
small GTPase regulator activityGO:0005083266.67%0.88%2.28E-4(0.37)
GTPase regulator activityGO:0030695266.67%1.04%3.16E-4(0.51)
zinc ion bindingGO:0008270133.33%0.03%9.29E-4(n.s)
enzyme regulator activityGO:0030234266.67%2.54%1.89E-3(n.s)
transition metal ion bindingGO:0046914133.33%0.12%3.71E-3(n.s)
cation bindingGO:0043169133.33%0.19%5.57E-3(n.s)
metal ion bindingGO:0046872133.33%0.25%7.42E-3(n.s)
ion bindingGO:0043167133.33%0.25%7.42E-3(n.s)
GTPase activityGO:0003924133.33%0.91%0.03(n.s)
nucleoside-triphosphatase activityGO:0017111133.33%3.42%0.1(n.s)
pyrophosphatase activityGO:0016462133.33%3.67%0.11(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817133.33%3.69%0.11(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818133.33%3.69%0.11(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
bindingGO:0005488133.33%17.35%0.44(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytoplasmic vesicleGO:0031410266.67%1.16%3.97E-4(0.64)
cytoplasmic membrane-bound vesicleGO:0016023266.67%1.16%3.97E-4(0.64)
transport vesicleGO:0030133133.33%0.19%5.57E-3(n.s)
actin capGO:0030478133.33%0.23%6.96E-3(n.s)
incipient bud siteGO:0000131133.33%0.51%0.02(n.s)
soluble fractionGO:0005625133.33%0.56%0.02(n.s)
cortical cytoskeletonGO:0030863133.33%0.84%0.02(n.s)
cortical actin cytoskeletonGO:0030864133.33%0.84%0.02(n.s)
membrane fractionGO:0005624133.33%1.22%0.04(n.s)
actin cytoskeletonGO:0015629133.33%1.38%0.04(n.s)
cell cortexGO:0005938133.33%1.52%0.04(n.s)
cell fractionGO:0000267133.33%1.72%0.05(n.s)
cytoskeletonGO:0005856133.33%2.93%0.09(n.s)
cytosolGO:0005829133.33%10.08%0.27(n.s)
intracellular non-membrane-bound organelleGO:0043232133.33%14.3%0.37(n.s)
non-membrane-bound organelleGO:0043228133.33%14.3%0.37(n.s)
mitochondrionGO:0005739133.33%15.78%0.4(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cytoplasmGO:0005737266.67%55.64%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
intracellularGO:0005622266.67%77.03%0.87(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_97 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA metabolismGO:00160703100%8.32%5.73E-4(0.93)
Group I intron splicingGO:0000372133.33%0.11%3.25E-3(n.s)
RNA splicing, via transesterification reactions with guanosine as nucleophileGO:0000376133.33%0.11%3.25E-3(n.s)
RNA processingGO:0006396266.67%5.33%8.19E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061393100%23.17%0.01(n.s)
biopolymer metabolismGO:00432833100%25.06%0.02(n.s)
mRNA catabolismGO:0006402133.33%0.85%0.03(n.s)
RNA catabolismGO:0006401133.33%0.99%0.03(n.s)
aerobic respirationGO:0009060133.33%1.27%0.04(n.s)
cellular respirationGO:0045333133.33%1.35%0.04(n.s)
RNA splicing, via transesterification reactionsGO:0000375133.33%1.63%0.05(n.s)
RNA splicingGO:0008380133.33%1.95%0.06(n.s)
mRNA metabolismGO:0016071133.33%2.85%0.08(n.s)
energy derivation by oxidation of organic compoundsGO:0015980133.33%3.04%0.09(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular macromolecule catabolismGO:0044265133.33%4.51%0.13(n.s)
macromolecule catabolismGO:0009057133.33%4.83%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA bindingGO:0003723266.67%5.96%0.01(n.s)
mRNA bindingGO:0003729133.33%0.5%0.01(n.s)
RNA splicing factor activity, transesterification mechanismGO:0031202133.33%0.65%0.02(n.s)
nucleic acid bindingGO:0003676266.67%9.87%0.03(n.s)
bindingGO:0005488266.67%17.35%0.08(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
mitochondrial membraneGO:0005740133.33%3.16%0.09(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
organelle membraneGO:0031090133.33%8.58%0.24(n.s)
membraneGO:0016020133.33%15.38%0.39(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_96 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
oligopeptide transportGO:0006857133.33%0.03%9.29E-4(n.s)
peptide transportGO:0015833133.33%0.06%1.86E-3(n.s)
iron ion homeostasisGO:0006879133.33%0.45%0.01(n.s)
transition metal ion homeostasisGO:0046916133.33%0.73%0.02(n.s)
di-, tri-valent inorganic cation homeostasisGO:0030005133.33%0.81%0.02(n.s)
metal ion homeostasisGO:0006875133.33%0.91%0.03(n.s)
aerobic respirationGO:0009060133.33%1.27%0.04(n.s)
cation homeostasisGO:0030003133.33%1.35%0.04(n.s)
cellular respirationGO:0045333133.33%1.35%0.04(n.s)
cell ion homeostasisGO:0006873133.33%1.49%0.04(n.s)
ion homeostasisGO:0050801133.33%1.55%0.05(n.s)
cell homeostasisGO:0019725133.33%1.64%0.05(n.s)
homeostasisGO:0042592133.33%1.73%0.05(n.s)
energy derivation by oxidation of organic compoundsGO:0015980133.33%3.04%0.09(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesGO:00168203100%0.87%6.18E-7(9.99E-4)
ATPase activity, coupled to transmembrane movement of substancesGO:00426263100%0.87%6.18E-7(9.99E-4)
ATPase activity, coupledGO:00426233100%1.58%3.83E-6(6.19E-3)
ATPase activityGO:00168873100%2.52%1.58E-5(0.03)
nucleoside-triphosphatase activityGO:00171113100%3.42%3.96E-5(0.06)
pyrophosphatase activityGO:00164623100%3.67%4.89E-5(0.08)
hydrolase activity, acting on acid anhydridesGO:00168173100%3.69%4.95E-5(0.08)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:00168183100%3.69%4.95E-5(0.08)
transporter activityGO:00052153100%6.64%2.92E-4(0.47)
peptide-transporting ATPase activityGO:0015440133.33%0.02%**
hydrolase activityGO:00167873100%11.45%1.49E-3(n.s)
peptide transporter activityGO:0015197133.33%0.08%2.32E-3(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:00057433100%2.43%1.41E-5(0.02)
inner membraneGO:00198663100%2.43%1.41E-5(0.02)
mitochondrial membraneGO:00057403100%3.16%3.11E-5(0.05)
organelle membraneGO:00310903100%8.58%6.29E-4(n.s)
membraneGO:00160203100%15.38%3.63E-3(n.s)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_11 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
amino acid derivative catabolismGO:0042219150%0.06%1.24E-3(n.s)
amino acid derivative metabolismGO:0006575150%0.42%8.35E-3(n.s)
sporulation (sensu Fungi)GO:0030437150%1.38%0.03(n.s)
reproductive sporulationGO:0048622150%1.38%0.03(n.s)
sporulationGO:0030435150%1.56%0.03(n.s)
cell differentiationGO:0030154150%1.6%0.03(n.s)
reproductive physiological processGO:0050876150%2.93%0.06(n.s)
reproductive cellular physiological processGO:0048610150%2.93%0.06(n.s)
amino acid and derivative metabolismGO:0006519150%3.05%0.06(n.s)
reproductionGO:0000003150%3.92%0.08(n.s)
developmentGO:0007275150%5.73%0.11(n.s)
cellular catabolismGO:0044248150%5.84%0.11(n.s)
catabolismGO:0009056150%6.16%0.12(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
threo-3-hydroxyaspartate ammonia-lyase activityGO:0030848150%0.02%**
serine racemase activityGO:0030378150%0.02%**
racemase and epimerase activity, acting on amino acids and derivativesGO:0016855150%0.03%6.2E-4(n.s)
ammonia-lyase activityGO:0016841150%0.06%1.24E-3(n.s)
racemase and epimerase activityGO:0016854150%0.06%1.24E-3(n.s)
carbon-nitrogen lyase activityGO:0016840150%0.09%1.86E-3(n.s)
isomerase activityGO:0016853150%0.81%0.02(n.s)
lyase activityGO:0016829150%1.27%0.03(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cellular component unknownGO:0008372150%15.74%0.29(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
intracellularGO:0005622150%77.03%0.95(n.s)
cellGO:0005623150%83.5%0.97(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_13 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial genome maintenanceGO:0000002375%0.42%2.6E-7(4.21E-4)
mitochondrion organization and biogenesisGO:0007005375%1.47%1.22E-5(0.02)
isoleucine biosynthesisGO:0009097125%0.02%**
guanine nucleotide transportGO:0001408125%0.02%**
isoleucine metabolismGO:0006549125%0.05%1.86E-3(n.s)
purine nucleotide transportGO:0015865125%0.05%1.86E-3(n.s)
nucleotide transportGO:0006862125%0.05%1.86E-3(n.s)
branched chain family amino acid biosynthesisGO:0009082125%0.2%8.03E-3(n.s)
branched chain family amino acid metabolismGO:0009081125%0.25%9.88E-3(n.s)
organelle organization and biogenesisGO:0006996375%15.69%0.01(n.s)
mitochondrion inheritanceGO:0000001125%0.39%0.02(n.s)
mitochondrion distributionGO:0048311125%0.39%0.02(n.s)
iron ion homeostasisGO:0006879125%0.45%0.02(n.s)
cell organization and biogenesisGO:0016043375%17.98%0.02(n.s)
organelle inheritanceGO:0048308125%0.57%0.02(n.s)
transition metal ion homeostasisGO:0046916125%0.73%0.03(n.s)
di-, tri-valent inorganic cation homeostasisGO:0030005125%0.81%0.03(n.s)
metal ion homeostasisGO:0006875125%0.91%0.04(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid transportGO:0015931125%1.21%0.05(n.s)
cation homeostasisGO:0030003125%1.35%0.05(n.s)
cell ion homeostasisGO:0006873125%1.49%0.06(n.s)
amino acid biosynthesisGO:0008652125%1.53%0.06(n.s)
ion homeostasisGO:0050801125%1.55%0.06(n.s)
cell homeostasisGO:0019725125%1.64%0.06(n.s)
nitrogen compound biosynthesisGO:0044271125%1.67%0.07(n.s)
amine biosynthesisGO:0009309125%1.67%0.07(n.s)
homeostasisGO:0042592125%1.73%0.07(n.s)
amino acid metabolismGO:0006520125%2.82%0.11(n.s)
amino acid and derivative metabolismGO:0006519125%3.05%0.12(n.s)
amine metabolismGO:0009308125%3.38%0.13(n.s)
nitrogen compound metabolismGO:0006807125%3.66%0.14(n.s)
organic acid metabolismGO:0006082125%4.6%0.17(n.s)
carboxylic acid metabolismGO:0019752125%4.6%0.17(n.s)
transportGO:0006810125%14.27%0.46(n.s)
establishment of localizationGO:0051234125%14.39%0.46(n.s)
localizationGO:0051179125%14.82%0.47(n.s)
cellular biosynthesisGO:0044249125%17.05%0.53(n.s)
biosynthesisGO:0009058125%18.28%0.55(n.s)
cellular physiological processGO:0050875375%71.65%0.68(n.s)
cellular processGO:0009987375%72.29%0.69(n.s)
biological process unknownGO:0000004125%25.64%0.69(n.s)
physiological processGO:0007582375%73.68%0.72(n.s)
primary metabolismGO:0044238125%48.71%0.93(n.s)
cellular metabolismGO:0044237125%52.12%0.95(n.s)
metabolismGO:0008152125%52.93%0.95(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
guanine nucleotide transporter activityGO:0001409125%0.02%**
purine nucleotide transporter activityGO:0015216125%0.03%1.24E-3(n.s)
nucleotide transporter activityGO:0015215125%0.03%1.24E-3(n.s)
DNA bending activityGO:0008301125%0.11%4.33E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid transporter activityGO:0015932125%0.14%5.57E-3(n.s)
DNA bindingGO:0003677125%3.18%0.12(n.s)
transporter activityGO:0005215125%6.64%0.24(n.s)
nucleic acid bindingGO:0003676125%9.87%0.34(n.s)
molecular function unknownGO:0005554250%35.75%0.45(n.s)
bindingGO:0005488125%17.35%0.53(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial chromosomeGO:0000262125%0.03%1.24E-3(n.s)
mitochondrial matrixGO:0005759250%2.52%3.68E-3(n.s)
mitochondrionGO:0005739375%15.78%0.01(n.s)
nucleoidGO:0009295125%0.36%0.01(n.s)
mitochondrial nucleoidGO:0042645125%0.36%0.01(n.s)
mitochondrial inner membraneGO:0005743125%2.43%0.09(n.s)
inner membraneGO:0019866125%2.43%0.09(n.s)
cytoplasmGO:00057374100%55.64%0.1(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
chromosomeGO:0005694125%3.16%0.12(n.s)
mitochondrial membraneGO:0005740125%3.16%0.12(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
organelle membraneGO:0031090125%8.58%0.3(n.s)
cytosolGO:0005829125%10.08%0.35(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
intracellular non-membrane-bound organelleGO:0043232125%14.3%0.46(n.s)
non-membrane-bound organelleGO:0043228125%14.3%0.46(n.s)
cellGO:00056234100%83.5%0.49(n.s)
membraneGO:0016020125%15.38%0.49(n.s)
nucleusGO:0005634125%31.01%0.77(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_14 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
inner mitochondrial membrane organization and biogenesisGO:0007007133.33%0.2%6.03E-3(n.s)
mitochondrial membrane organization and biogenesisGO:0007006133.33%0.29%8.8E-3(n.s)
ATP synthesis coupled electron transportGO:0042773133.33%0.39%0.01(n.s)
ATP synthesis coupled electron transport (sensu Eukaryota)GO:0042775133.33%0.39%0.01(n.s)
membrane organization and biogenesisGO:0016044133.33%0.48%0.01(n.s)
electron transportGO:0006118133.33%0.48%0.01(n.s)
oxidative phosphorylationGO:0006119133.33%0.71%0.02(n.s)
phospholipid biosynthesisGO:0008654133.33%0.81%0.02(n.s)
membrane lipid biosynthesisGO:0046467133.33%1.1%0.03(n.s)
phospholipid metabolismGO:0006644133.33%1.19%0.04(n.s)
mitochondrion organization and biogenesisGO:0007005133.33%1.47%0.04(n.s)
membrane lipid metabolismGO:0006643133.33%1.61%0.05(n.s)
lipid biosynthesisGO:0008610133.33%1.92%0.06(n.s)
phosphorylationGO:0016310133.33%2.21%0.06(n.s)
phosphate metabolismGO:0006796133.33%2.91%0.08(n.s)
phosphorus metabolismGO:0006793133.33%2.91%0.08(n.s)
cellular lipid metabolismGO:0044255133.33%3.16%0.09(n.s)
lipid metabolismGO:0006629133.33%3.38%0.1(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
biological process unknownGO:0000004266.67%25.64%0.16(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
organelle organization and biogenesisGO:0006996133.33%15.69%0.4(n.s)
cell organization and biogenesisGO:0016043133.33%17.98%0.45(n.s)
biosynthesisGO:0009058133.33%18.28%0.45(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
cellular physiological processGO:0050875133.33%71.65%0.98(n.s)
cellular processGO:0009987133.33%72.29%0.98(n.s)
physiological processGO:0007582133.33%73.68%0.98(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
acyltransferase activityGO:0008415133.33%1.19%0.04(n.s)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747133.33%1.19%0.04(n.s)
transferase activity, transferring acyl groupsGO:0016746133.33%1.43%0.04(n.s)
transferase activityGO:0016740133.33%10.13%0.27(n.s)
molecular function unknownGO:0005554266.67%35.75%0.29(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
cellular component unknownGO:0008372133.33%15.74%0.4(n.s)
cytoplasmGO:0005737266.67%55.64%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
intracellularGO:0005622266.67%77.03%0.87(n.s)
cellGO:0005623266.67%83.5%0.93(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_19 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
glycyl-tRNA aminoacylationGO:0006426125%0.03%1.24E-3(n.s)
amino acid metabolismGO:0006520250%2.82%4.57E-3(n.s)
amino acid and derivative metabolismGO:0006519250%3.05%5.34E-3(n.s)
lysine biosynthesisGO:0009085125%0.14%5.57E-3(n.s)
lysine metabolismGO:0006553125%0.14%5.57E-3(n.s)
amine metabolismGO:0009308250%3.38%6.51E-3(n.s)
karyogamyGO:0000741125%0.19%7.42E-3(n.s)
nitrogen compound metabolismGO:0006807250%3.66%7.6E-3(n.s)
pigment biosynthesisGO:0046148125%0.22%8.65E-3(n.s)
porphyrin biosynthesisGO:0006779125%0.22%8.65E-3(n.s)
heme biosynthesisGO:0006783125%0.22%8.65E-3(n.s)
heme metabolismGO:0042168125%0.23%9.26E-3(n.s)
porphyrin metabolismGO:0006778125%0.23%9.26E-3(n.s)
pigment metabolismGO:0042440125%0.23%9.26E-3(n.s)
organelle fusionGO:0048284125%0.26%0.01(n.s)
transcription terminationGO:0006353125%0.26%0.01(n.s)
secondary metabolismGO:0019748125%0.28%0.01(n.s)
aspartate family amino acid biosynthesisGO:0009067125%0.28%0.01(n.s)
organic acid metabolismGO:0006082250%4.6%0.01(n.s)
carboxylic acid metabolismGO:0019752250%4.6%0.01(n.s)
cellular biosynthesisGO:0044249375%17.05%0.02(n.s)
tRNA aminoacylationGO:0043039125%0.46%0.02(n.s)
amino acid activationGO:0043038125%0.46%0.02(n.s)
tRNA aminoacylation for protein translationGO:0006418125%0.46%0.02(n.s)
biosynthesisGO:0009058375%18.28%0.02(n.s)
aspartate family amino acid metabolismGO:0009066125%0.7%0.03(n.s)
nuclear organization and biogenesisGO:0006997125%1.01%0.04(n.s)
tRNA modificationGO:0006400125%1.02%0.04(n.s)
cofactor biosynthesisGO:0051188125%1.08%0.04(n.s)
heterocycle metabolismGO:0046483125%1.1%0.04(n.s)
amino acid biosynthesisGO:0008652125%1.53%0.06(n.s)
tRNA metabolismGO:0006399125%1.6%0.06(n.s)
amine biosynthesisGO:0009309125%1.67%0.07(n.s)
nitrogen compound biosynthesisGO:0044271125%1.67%0.07(n.s)
cofactor metabolismGO:0051186125%2.26%0.09(n.s)
RNA modificationGO:0009451125%2.42%0.09(n.s)
translationGO:0043037125%6.47%0.23(n.s)
transcription, DNA-dependentGO:0006351125%6.78%0.25(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
transcriptionGO:0006350125%7.43%0.27(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
RNA metabolismGO:0016070125%8.32%0.29(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
biopolymer modificationGO:0043412125%9.25%0.32(n.s)
cellular metabolismGO:0044237375%52.12%0.34(n.s)
metabolismGO:0008152375%52.93%0.36(n.s)
protein biosynthesisGO:0006412125%12.16%0.4(n.s)
macromolecule biosynthesisGO:0009059125%13.04%0.43(n.s)
organelle organization and biogenesisGO:0006996125%15.69%0.49(n.s)
cell organization and biogenesisGO:0016043125%17.98%0.55(n.s)
cellular protein metabolismGO:0044267125%21.7%0.62(n.s)
protein metabolismGO:0019538125%22.06%0.63(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139125%23.17%0.65(n.s)
primary metabolismGO:0044238250%48.71%0.67(n.s)
cellular macromolecule metabolismGO:0044260125%24.52%0.68(n.s)
biopolymer metabolismGO:0043283125%25.06%0.68(n.s)
macromolecule metabolismGO:0043170125%26.04%0.7(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
N-succinyltransferase activityGO:0016749125%0.02%**
5-aminolevulinate synthase activityGO:0003870125%0.02%**
homoisocitrate dehydrogenase activityGO:0047046125%0.02%**
succinyltransferase activityGO:0016748125%0.03%1.24E-3(n.s)
glycine-tRNA ligase activityGO:0004820125%0.03%1.24E-3(n.s)
ligase activity, forming carbon-oxygen bondsGO:0016875125%0.56%0.02(n.s)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876125%0.56%0.02(n.s)
tRNA ligase activityGO:0004812125%0.56%0.02(n.s)
RNA ligase activityGO:0008452125%0.57%0.02(n.s)
N-acyltransferase activityGO:0016410125%0.59%0.02(n.s)
ligase activity, forming phosphoric ester bondsGO:0016886125%0.62%0.02(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:0016616125%1.07%0.04(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614125%1.18%0.05(n.s)
acyltransferase activityGO:0008415125%1.19%0.05(n.s)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747125%1.19%0.05(n.s)
transferase activity, transferring acyl groupsGO:0016746125%1.43%0.06(n.s)
ligase activityGO:0016874125%1.89%0.07(n.s)
catalytic activityGO:0003824375%29.21%0.08(n.s)
oxidoreductase activityGO:0016491125%3.73%0.14(n.s)
transferase activityGO:0016740125%10.13%0.35(n.s)
molecular function unknownGO:0005554125%35.75%0.83(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739375%15.78%0.01(n.s)
cytoplasmGO:00057374100%55.64%0.1(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
mitochondrial matrixGO:0005759125%2.52%0.1(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
cellGO:00056234100%83.5%0.49(n.s)
nucleusGO:0005634125%31.01%0.77(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_18 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
carbon utilization by utilization of organic compoundsGO:0015978125%0.02%**
carbon utilizationGO:0015976125%0.03%1.24E-3(n.s)
energy derivation by oxidation of organic compoundsGO:0015980250%3.04%5.28E-3(n.s)
cytochrome c oxidase complex assemblyGO:0008535125%0.14%5.57E-3(n.s)
generation of precursor metabolites and energyGO:0006091250%3.5%6.99E-3(n.s)
gluconeogenesisGO:0006094125%0.4%0.02(n.s)
monosaccharide biosynthesisGO:0046364125%0.43%0.02(n.s)
hexose biosynthesisGO:0019319125%0.43%0.02(n.s)
alcohol biosynthesisGO:0046165125%0.46%0.02(n.s)
pyruvate metabolismGO:0006090125%0.57%0.02(n.s)
carbohydrate biosynthesisGO:0016051125%0.91%0.04(n.s)
glucose metabolismGO:0006006125%1.01%0.04(n.s)
main pathways of carbohydrate metabolismGO:0006092125%1.08%0.04(n.s)
aerobic respirationGO:0009060125%1.27%0.05(n.s)
hexose metabolismGO:0019318125%1.32%0.05(n.s)
cellular respirationGO:0045333125%1.35%0.05(n.s)
sporulation (sensu Fungi)GO:0030437125%1.38%0.05(n.s)
reproductive sporulationGO:0048622125%1.38%0.05(n.s)
monosaccharide metabolismGO:0005996125%1.43%0.06(n.s)
sporulationGO:0030435125%1.56%0.06(n.s)
cell differentiationGO:0030154125%1.6%0.06(n.s)
external encapsulating structure organization and biogenesisGO:0045229125%2.17%0.08(n.s)
cell wall organization and biogenesisGO:0007047125%2.17%0.08(n.s)
protein complex assemblyGO:0006461125%2.26%0.09(n.s)
alcohol metabolismGO:0006066125%2.43%0.09(n.s)
reproductive physiological processGO:0050876125%2.93%0.11(n.s)
reproductive cellular physiological processGO:0048610125%2.93%0.11(n.s)
cellular carbohydrate metabolismGO:0044262125%3.08%0.12(n.s)
carbohydrate metabolismGO:0005975125%3.38%0.13(n.s)
reproductionGO:0000003125%3.92%0.15(n.s)
organic acid metabolismGO:0006082125%4.6%0.17(n.s)
carboxylic acid metabolismGO:0019752125%4.6%0.17(n.s)
developmentGO:0007275125%5.73%0.21(n.s)
cellular macromolecule metabolismGO:0044260250%24.52%0.25(n.s)
cellular physiological processGO:00508754100%71.65%0.26(n.s)
cellular processGO:00099874100%72.29%0.27(n.s)
macromolecule metabolismGO:0043170250%26.04%0.28(n.s)
physiological processGO:00075824100%73.68%0.29(n.s)
macromolecule biosynthesisGO:0009059125%13.04%0.43(n.s)
cellular biosynthesisGO:0044249125%17.05%0.53(n.s)
cell organization and biogenesisGO:0016043125%17.98%0.55(n.s)
biosynthesisGO:0009058125%18.28%0.55(n.s)
cellular protein metabolismGO:0044267125%21.7%0.62(n.s)
protein metabolismGO:0019538125%22.06%0.63(n.s)
primary metabolismGO:0044238250%48.71%0.67(n.s)
cellular metabolismGO:0044237250%52.12%0.72(n.s)
metabolismGO:0008152250%52.93%0.73(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
unfolded protein bindingGO:0051082125%0.9%0.04(n.s)
molecular function unknownGO:0005554375%35.75%0.13(n.s)
protein bindingGO:0005515125%7.39%0.26(n.s)
bindingGO:0005488125%17.35%0.53(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial intermembrane spaceGO:0005758125%0.39%0.02(n.s)
mitochondrial inner membraneGO:0005743125%2.43%0.09(n.s)
inner membraneGO:0019866125%2.43%0.09(n.s)
cellular component unknownGO:0008372250%15.74%0.12(n.s)
mitochondrionGO:0005739250%15.78%0.12(n.s)
mitochondrial membraneGO:0005740125%3.16%0.12(n.s)
organelle membraneGO:0031090125%8.58%0.3(n.s)
membraneGO:0016020125%15.38%0.49(n.s)
cytoplasmGO:0005737250%55.64%0.77(n.s)
intracellular membrane-bound organelleGO:0043231250%55.65%0.77(n.s)
membrane-bound organelleGO:0043227250%55.65%0.77(n.s)
organelleGO:0043226250%60.56%0.83(n.s)
intracellular organelleGO:0043229250%60.56%0.83(n.s)
intracellularGO:0005622250%77.03%0.96(n.s)
cellGO:0005623250%83.5%0.98(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_117 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytochrome c oxidase complex assemblyGO:00085352100%0.14%1.73E-6(2.79E-3)
protein complex assemblyGO:00064612100%2.26%5.08E-4(0.82)
cellular protein metabolismGO:00442672100%21.7%0.05(n.s)
protein metabolismGO:00195382100%22.06%0.05(n.s)
cellular macromolecule metabolismGO:00442602100%24.52%0.06(n.s)
macromolecule metabolismGO:00431702100%26.04%0.07(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membraneGO:00057432100%2.43%5.88E-4(0.95)
inner membraneGO:00198662100%2.43%5.88E-4(0.95)
mitochondrial membraneGO:00057402100%3.16%9.94E-4(n.s)
organelle membraneGO:00310902100%8.58%7.35E-3(n.s)
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_116 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial genome maintenanceGO:0000002150%0.42%8.35E-3(n.s)
mitochondrion organization and biogenesisGO:0007005150%1.47%0.03(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
helicase activityGO:00043862100%1.3%1.67E-4(0.27)
ATP-dependent DNA helicase activityGO:0004003150%0.15%3.1E-3(n.s)
DNA-dependent ATPase activityGO:0008094150%0.26%5.26E-3(n.s)
DNA helicase activityGO:0003678150%0.43%8.66E-3(n.s)
ATP-dependent helicase activityGO:0008026150%0.57%0.01(n.s)
ATPase activity, coupledGO:0042623150%1.58%0.03(n.s)
ATPase activityGO:0016887150%2.52%0.05(n.s)
nucleoside-triphosphatase activityGO:0017111150%3.42%0.07(n.s)
pyrophosphatase activityGO:0016462150%3.67%0.07(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817150%3.69%0.07(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818150%3.69%0.07(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial matrixGO:0005759150%2.52%0.05(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_151 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
rRNA processingGO:00063643100%2.71%1.96E-5(0.03)
ribosome biogenesisGO:00070463100%3.3%3.54E-5(0.06)
ribosome biogenesis and assemblyGO:00422543100%3.9%5.88E-5(0.1)
cytoplasm organization and biogenesisGO:00070283100%3.9%5.88E-5(0.1)
rRNA metabolismGO:00160723100%3.92%5.95E-5(0.1)
processing of 20S pre-rRNAGO:0030490266.67%0.71%1.48E-4(0.24)
RNA processingGO:00063963100%5.33%1.5E-4(0.24)
RNA metabolismGO:00160703100%8.32%5.73E-4(0.93)
ribosomal small subunit biogenesisGO:0042274133.33%0.06%1.86E-3(n.s)
organelle organization and biogenesisGO:00069963100%15.69%3.85E-3(n.s)
cell organization and biogenesisGO:00160433100%17.98%5.8E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061393100%23.17%0.01(n.s)
biopolymer metabolismGO:00432833100%25.06%0.02(n.s)
35S primary transcript processingGO:0006365133.33%1.04%0.03(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
snoRNA bindingGO:00305153100%0.45%8.15E-8(1.32E-4)
RNA bindingGO:00037233100%5.96%2.11E-4(0.34)
nucleic acid bindingGO:00036763100%9.87%9.56E-4(n.s)
bindingGO:00054883100%17.35%5.21E-3(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nucleolar preribosome, small subunit precursorGO:0030688266.67%0.03%1.44E-7(2.33E-4)
Noc4p-Nop14p complexGO:0030692266.67%0.03%1.44E-7(2.33E-4)
small nucleolar ribonucleoprotein complexGO:00057323100%0.88%6.53E-7(1.05E-3)
Noc complexGO:0030689266.67%0.08%1.44E-6(2.33E-3)
90S preribosomeGO:0030686266.67%0.08%1.44E-6(2.33E-3)
nucleolar preribosomeGO:0030685266.67%0.12%4.03E-6(6.51E-3)
preribosomeGO:0030684266.67%0.14%5.18E-6(8.37E-3)
nucleolusGO:00057303100%4.58%9.54E-5(0.15)
ribonucleoprotein complexGO:00305293100%7.19%3.69E-4(0.6)
nuclear microtubuleGO:0005880133.33%0.09%2.79E-3(n.s)
intracellular non-membrane-bound organelleGO:00432323100%14.3%2.91E-3(n.s)
non-membrane-bound organelleGO:00432283100%14.3%2.91E-3(n.s)
protein complexGO:00432343100%21.07%9.33E-3(n.s)
microtubuleGO:0005874133.33%0.56%0.02(n.s)
nucleusGO:00056343100%31.01%0.03(n.s)
microtubule cytoskeletonGO:0015630133.33%1.47%0.04(n.s)
cytoskeletonGO:0005856133.33%2.93%0.09(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
mitochondrionGO:0005739133.33%15.78%0.4(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_150 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein foldingGO:00064572100%1.04%1.06E-4(0.17)
proteasome assemblyGO:0043248150%0.08%1.55E-3(n.s)
protein complex assemblyGO:0006461150%2.26%0.04(n.s)
cellular protein metabolismGO:00442672100%21.7%0.05(n.s)
protein metabolismGO:00195382100%22.06%0.05(n.s)
cellular macromolecule metabolismGO:00442602100%24.52%0.06(n.s)
macromolecule metabolismGO:00431702100%26.04%0.07(n.s)
response to stressGO:0006950150%6.09%0.12(n.s)
response to stimulusGO:0050896150%8.41%0.16(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
unfolded protein bindingGO:00510822100%0.9%7.93E-5(0.13)
cis-trans isomerase activityGO:0016859150%0.2%4.02E-3(n.s)
peptidyl-prolyl cis-trans isomerase activityGO:0003755150%0.2%4.02E-3(n.s)
protein bindingGO:00055152100%7.39%5.45E-3(n.s)
isomerase activityGO:0016853150%0.81%0.02(n.s)
bindingGO:00054882100%17.35%0.03(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_153 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lactate metabolismGO:0006089133.33%0.03%9.29E-4(n.s)
bipolar bud site selectionGO:0007121133.33%0.5%0.01(n.s)
response to osmotic stressGO:0006970133.33%0.91%0.03(n.s)
actin filament organizationGO:0007015133.33%0.98%0.03(n.s)
bud site selectionGO:0000282133.33%1.01%0.03(n.s)
cytokinesis, site selectionGO:0007105133.33%1.01%0.03(n.s)
endocytosisGO:0006897133.33%1.07%0.03(n.s)
cell buddingGO:0007114133.33%1.19%0.04(n.s)
asexual reproductionGO:0019954133.33%1.19%0.04(n.s)
cytokinesisGO:0000910133.33%1.5%0.04(n.s)
actin cytoskeleton organization and biogenesisGO:0030036133.33%1.55%0.05(n.s)
establishment of cell polarity (sensu Fungi)GO:0030468133.33%1.6%0.05(n.s)
establishment of cell polarityGO:0030010133.33%1.6%0.05(n.s)
actin filament-based processGO:0030029133.33%1.61%0.05(n.s)
establishment and/or maintenance of cell polarity (sensu Fungi)GO:0030467133.33%1.66%0.05(n.s)
establishment and/or maintenance of cell polarityGO:0007163133.33%1.66%0.05(n.s)
cell divisionGO:0051301133.33%1.91%0.06(n.s)
cellular morphogenesisGO:0000902133.33%2.23%0.07(n.s)
morphogenesisGO:0009653133.33%2.23%0.07(n.s)
response to abiotic stimulusGO:0009628133.33%3.52%0.1(n.s)
response to external stimulusGO:0009605133.33%3.87%0.11(n.s)
reproductionGO:0000003133.33%3.92%0.11(n.s)
vesicle-mediated transportGO:0016192133.33%4.34%0.12(n.s)
cytoskeleton organization and biogenesisGO:0007010133.33%4.48%0.13(n.s)
organic acid metabolismGO:0006082133.33%4.6%0.13(n.s)
carboxylic acid metabolismGO:0019752133.33%4.6%0.13(n.s)
developmentGO:0007275133.33%5.73%0.16(n.s)
biological process unknownGO:0000004266.67%25.64%0.16(n.s)
response to stressGO:0006950133.33%6.09%0.17(n.s)
response to stimulusGO:0050896133.33%8.41%0.23(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
organelle organization and biogenesisGO:0006996133.33%15.69%0.4(n.s)
cell organization and biogenesisGO:0016043133.33%17.98%0.45(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
cellular metabolismGO:0044237133.33%52.12%0.89(n.s)
metabolismGO:0008152133.33%52.93%0.9(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
actin bindingGO:0003779266.67%0.25%1.73E-5(0.03)
cytoskeletal protein bindingGO:0008092266.67%0.74%1.62E-4(0.26)
NADPH dehydrogenase activityGO:0003959133.33%0.03%9.29E-4(n.s)
D-lactate dehydrogenase (cytochrome) activityGO:0004458133.33%0.05%1.39E-3(n.s)
oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptorGO:0016898133.33%0.06%1.86E-3(n.s)
lactate dehydrogenase activityGO:0004457133.33%0.06%1.86E-3(n.s)
actin filament bindingGO:0051015133.33%0.12%3.71E-3(n.s)
oxidoreductase activityGO:0016491266.67%3.73%4.06E-3(n.s)
oxidoreductase activity, acting on NADH or NADPHGO:0016651133.33%0.14%4.18E-3(n.s)
protein binding, bridgingGO:0030674133.33%0.2%6.03E-3(n.s)
electron transporter activityGO:0005489133.33%0.34%0.01(n.s)
protein bindingGO:0005515266.67%7.39%0.02(n.s)
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614133.33%1.18%0.03(n.s)
bindingGO:0005488266.67%17.35%0.08(n.s)
transporter activityGO:0005215133.33%6.64%0.19(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
actin cableGO:0030482133.33%0.08%2.32E-3(n.s)
actin cortical patchGO:0030479133.33%0.62%0.02(n.s)
cortical cytoskeletonGO:0030863133.33%0.84%0.02(n.s)
cortical actin cytoskeletonGO:0030864133.33%0.84%0.02(n.s)
actin cytoskeletonGO:0015629133.33%1.38%0.04(n.s)
cell cortexGO:0005938133.33%1.52%0.04(n.s)
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
mitochondrial matrixGO:0005759133.33%2.52%0.07(n.s)
cytoskeletonGO:0005856133.33%2.93%0.09(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellular non-membrane-bound organelleGO:0043232133.33%14.3%0.37(n.s)
non-membrane-bound organelleGO:0043228133.33%14.3%0.37(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
nucleusGO:0005634133.33%31.01%0.67(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_152 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial protein processingGO:00066272100%0.09%7.2E-7(1.16E-3)
protein processingGO:00164852100%0.51%2.53E-5(0.04)
protein-mitochondrial targetingGO:00066262100%0.73%5.19E-5(0.08)
protein targetingGO:00066052100%3.42%1.17E-3(n.s)
intracellular protein transportGO:00068862100%3.7%1.36E-3(n.s)
protein transportGO:00150312100%3.79%1.43E-3(n.s)
establishment of protein localizationGO:00451842100%3.95%1.55E-3(n.s)
protein localizationGO:00081042100%4.37%1.9E-3(n.s)
protein modificationGO:00064642100%6.68%4.45E-3(n.s)
intracellular transportGO:00469072100%7.53%5.66E-3(n.s)
biopolymer modificationGO:00434122100%9.25%8.54E-3(n.s)
transportGO:00068102100%14.27%0.02(n.s)
establishment of localizationGO:00512342100%14.39%0.02(n.s)
localizationGO:00511792100%14.82%0.02(n.s)
cellular protein metabolismGO:00442672100%21.7%0.05(n.s)
protein metabolismGO:00195382100%22.06%0.05(n.s)
cellular macromolecule metabolismGO:00442602100%24.52%0.06(n.s)
biopolymer metabolismGO:00432832100%25.06%0.06(n.s)
macromolecule metabolismGO:00431702100%26.04%0.07(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membrane peptidase activityGO:00042442100%0.03%4.8E-8(7.76E-5)
endopeptidase activityGO:00041752100%0.99%9.68E-5(0.16)
peptidase activityGO:00082332100%2.48%6.1E-4(0.99)
hydrolase activityGO:00167872100%11.45%0.01(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial inner membrane peptidase complexGO:00427202100%0.05%1.44E-7(2.33E-4)
mitochondrial inner membraneGO:00057432100%2.43%5.88E-4(0.95)
inner membraneGO:00198662100%2.43%5.88E-4(0.95)
mitochondrial membraneGO:00057402100%3.16%9.94E-4(n.s)
organelle membraneGO:00310902100%8.58%7.35E-3(n.s)
membraneGO:00160202100%15.38%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
protein complexGO:00432342100%21.07%0.04(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_154 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
regulation of transcription, DNA-dependentGO:0006355150%4.68%0.09(n.s)
regulation of transcriptionGO:0045449150%4.96%0.1(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219150%5.24%0.1(n.s)
regulation of cellular metabolismGO:0031323150%5.98%0.12(n.s)
regulation of metabolismGO:0019222150%6.37%0.12(n.s)
transcription, DNA-dependentGO:0006351150%6.78%0.13(n.s)
transcriptionGO:0006350150%7.43%0.14(n.s)
regulation of cellular physiological processGO:0051244150%8.49%0.16(n.s)
regulation of cellular processGO:0050794150%8.52%0.16(n.s)
regulation of physiological processGO:0050791150%8.77%0.17(n.s)
regulation of biological processGO:0050789150%8.97%0.17(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein bindingGO:0005515150%7.39%0.14(n.s)
bindingGO:0005488150%17.35%0.32(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
CCR4-NOT complexGO:0030014150%0.19%3.71E-3(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
transcription factor complexGO:0005667150%1.87%0.04(n.s)
nucleoplasmGO:0005654150%4.86%0.09(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
protein complexGO:0043234150%21.07%0.38(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_157 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
transcription from mitochondrial promoterGO:00063902100%0.05%1.44E-7(2.33E-4)
transcription, DNA-dependentGO:00063512100%6.78%4.59E-3(n.s)
transcriptionGO:00063502100%7.43%5.52E-3(n.s)
mitochondrial genome maintenanceGO:0000002150%0.42%8.35E-3(n.s)
mitochondrion organization and biogenesisGO:0007005150%1.47%0.03(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061392100%23.17%0.05(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA-directed RNA polymerase activityGO:0003899150%0.51%0.01(n.s)
transferase activityGO:00167402100%10.13%0.01(n.s)
transcription cofactor activityGO:0003712150%0.56%0.01(n.s)
transcription factor bindingGO:0008134150%0.6%0.01(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:0008757150%0.77%0.02(n.s)
methyltransferase activityGO:0008168150%1.1%0.02(n.s)
transferase activity, transferring one-carbon groupsGO:0016741150%1.13%0.02(n.s)
nucleotidyltransferase activityGO:0016779150%1.91%0.04(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
transcription regulator activityGO:0030528150%5%0.1(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772150%5.19%0.1(n.s)
protein bindingGO:0005515150%7.39%0.14(n.s)
bindingGO:0005488150%17.35%0.32(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial matrixGO:00057592100%2.52%6.34E-4(n.s)
nucleoidGO:0009295150%0.36%7.11E-3(n.s)
mitochondrial nucleoidGO:0042645150%0.36%7.11E-3(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_159 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA 3'-end processingGO:00311232100%0.33%1.01E-5(0.02)
mRNA processingGO:00063972100%2.03%4.09E-4(0.66)
snoRNA 3'-end processingGO:0031126150%0.03%6.2E-4(n.s)
mRNA metabolismGO:00160712100%2.85%8.08E-4(n.s)
snoRNA processingGO:0043144150%0.05%9.29E-4(n.s)
transcription termination from Pol II promoter, RNA polymerase(A)-independentGO:0030847150%0.12%2.48E-3(n.s)
RNA processingGO:00063962100%5.33%2.83E-3(n.s)
transcription termination from Pol II promoter, RNA polymerase(A) coupledGO:0030846150%0.15%3.1E-3(n.s)
snoRNA metabolismGO:0016074150%0.19%3.71E-3(n.s)
transcription termination from RNA polymerase II promoterGO:0006369150%0.23%4.64E-3(n.s)
transcription terminationGO:0006353150%0.26%5.26E-3(n.s)
mRNA polyadenylylationGO:0006378150%0.28%5.57E-3(n.s)
mRNA 3'-end processingGO:0031124150%0.31%6.19E-3(n.s)
RNA metabolismGO:00160702100%8.32%6.91E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061392100%23.17%0.05(n.s)
biopolymer metabolismGO:00432832100%25.06%0.06(n.s)
transcription from RNA polymerase II promoterGO:0006366150%4.29%0.08(n.s)
transcription, DNA-dependentGO:0006351150%6.78%0.13(n.s)
transcriptionGO:0006350150%7.43%0.14(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
RNA bindingGO:0003723150%5.96%0.12(n.s)
nucleic acid bindingGO:0003676150%9.87%0.19(n.s)
bindingGO:0005488150%17.35%0.32(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mRNA cleavage and polyadenylation specificity factor complexGO:0005847150%0.23%4.64E-3(n.s)
mRNA cleavage factor complexGO:0005849150%0.31%6.19E-3(n.s)
bud neckGO:0005935150%1.64%0.03(n.s)
budGO:0005933150%2.12%0.04(n.s)
site of polarized growthGO:0030427150%2.21%0.04(n.s)
nucleoplasmGO:0005654150%4.86%0.09(n.s)
protein complexGO:0043234150%21.07%0.38(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
cellGO:00056232100%83.5%0.7(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
intracellularGO:0005622150%77.03%0.95(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_158 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cation transportGO:00068123100%1.36%2.45E-6(3.96E-3)
ion transportGO:00068113100%1.64%4.3E-6(6.95E-3)
proton transportGO:0015992266.67%0.37%3.96E-5(0.06)
hydrogen transportGO:0006818266.67%0.37%3.96E-5(0.06)
regulation of pHGO:0006885266.67%0.4%4.67E-5(0.08)
monovalent inorganic cation transportGO:0015672266.67%0.45%5.83E-5(0.09)
ion homeostasisGO:0050801266.67%1.55%7.05E-4(n.s)
homeostasisGO:0042592266.67%1.73%8.85E-4(n.s)
transportGO:00068103100%14.27%2.9E-3(n.s)
establishment of localizationGO:00512343100%14.39%2.97E-3(n.s)
localizationGO:00511793100%14.82%3.25E-3(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrogen-exporting ATPase activity, phosphorylative mechanismGO:0008553266.67%0.03%1.44E-7(2.33E-4)
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanismGO:0015662266.67%0.23%1.51E-5(0.02)
P-P-bond-hydrolysis-driven transporter activityGO:0015405266.67%0.45%5.83E-5(0.09)
ATPase activity, coupled to transmembrane movement of ionsGO:0042625266.67%0.46%6.24E-5(0.1)
primary active transporter activityGO:0015399266.67%0.77%1.75E-4(0.28)
hydrogen ion transporter activityGO:0015078266.67%0.84%2.05E-4(0.33)
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesGO:0016820266.67%0.87%2.2E-4(0.36)
ATPase activity, coupled to transmembrane movement of substancesGO:0042626266.67%0.87%2.2E-4(0.36)
monovalent inorganic cation transporter activityGO:0015077266.67%0.88%2.28E-4(0.37)
ATPase activity, coupledGO:0042623266.67%1.58%7.34E-4(n.s)
carrier activityGO:0005386266.67%1.64%7.93E-4(n.s)
cation transporter activityGO:0008324266.67%1.89%1.05E-3(n.s)
ion transporter activityGO:0015075266.67%2.21%1.44E-3(n.s)
ATPase activityGO:0016887266.67%2.52%1.87E-3(n.s)
nucleoside-triphosphatase activityGO:0017111266.67%3.42%3.42E-3(n.s)
pyrophosphatase activityGO:0016462266.67%3.67%3.93E-3(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817266.67%3.69%3.96E-3(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818266.67%3.69%3.96E-3(n.s)
transporter activityGO:0005215266.67%6.64%0.01(n.s)
hydrolase activityGO:0016787266.67%11.45%0.04(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lipid raftGO:0045121133.33%0.08%2.32E-3(n.s)
membraneGO:00160203100%15.38%3.63E-3(n.s)
plasma membraneGO:0005886266.67%3.67%3.93E-3(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_47 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_44 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
ribosomal large subunit assembly and maintenanceGO:0000027250%0.6%2.12E-4(0.34)
ribosomal subunit assemblyGO:0042257250%0.81%3.78E-4(0.61)
ribosome assemblyGO:0042255250%0.99%5.73E-4(0.93)
protein complex assemblyGO:0006461250%2.26%2.96E-3(n.s)
cytoplasm organization and biogenesisGO:0007028250%3.9%8.64E-3(n.s)
ribosome biogenesis and assemblyGO:0042254250%3.9%8.64E-3(n.s)
translational initiationGO:0006413125%0.74%0.03(n.s)
cellular protein metabolismGO:0044267375%21.7%0.03(n.s)
protein metabolismGO:0019538375%22.06%0.04(n.s)
35S primary transcript processingGO:0006365125%1.04%0.04(n.s)
cellular macromolecule metabolismGO:0044260375%24.52%0.05(n.s)
macromolecule metabolismGO:0043170375%26.04%0.06(n.s)
rRNA processingGO:0006364125%2.71%0.1(n.s)
organelle organization and biogenesisGO:0006996250%15.69%0.12(n.s)
ribosome biogenesisGO:0007046125%3.3%0.13(n.s)
rRNA metabolismGO:0016072125%3.92%0.15(n.s)
cell organization and biogenesisGO:0016043250%17.98%0.15(n.s)
RNA processingGO:0006396125%5.33%0.2(n.s)
translationGO:0043037125%6.47%0.23(n.s)
primary metabolismGO:0044238375%48.71%0.29(n.s)
RNA metabolismGO:0016070125%8.32%0.29(n.s)
cellular metabolismGO:0044237375%52.12%0.34(n.s)
metabolismGO:0008152375%52.93%0.36(n.s)
protein biosynthesisGO:0006412125%12.16%0.4(n.s)
macromolecule biosynthesisGO:0009059125%13.04%0.43(n.s)
cellular biosynthesisGO:0044249125%17.05%0.53(n.s)
biosynthesisGO:0009058125%18.28%0.55(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139125%23.17%0.65(n.s)
cellular physiological processGO:0050875375%71.65%0.68(n.s)
biopolymer metabolismGO:0043283125%25.06%0.68(n.s)
cellular processGO:0009987375%72.29%0.69(n.s)
biological process unknownGO:0000004125%25.64%0.69(n.s)
physiological processGO:0007582375%73.68%0.72(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nucleoside-triphosphatase activityGO:0017111250%3.42%6.69E-3(n.s)
pyrophosphatase activityGO:0016462250%3.67%7.67E-3(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817250%3.69%7.73E-3(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818250%3.69%7.73E-3(n.s)
RNA-dependent ATPase activityGO:0008186125%0.42%0.02(n.s)
ATP-dependent RNA helicase activityGO:0004004125%0.42%0.02(n.s)
translation initiation factor activityGO:0003743125%0.46%0.02(n.s)
ATP-dependent helicase activityGO:0008026125%0.57%0.02(n.s)
RNA helicase activityGO:0003724125%0.64%0.03(n.s)
translation factor activity, nucleic acid bindingGO:0008135125%0.73%0.03(n.s)
translation regulator activityGO:0045182125%0.9%0.04(n.s)
GTPase activityGO:0003924125%0.91%0.04(n.s)
helicase activityGO:0004386125%1.3%0.05(n.s)
ATPase activity, coupledGO:0042623125%1.58%0.06(n.s)
hydrolase activityGO:0016787250%11.45%0.07(n.s)
ATPase activityGO:0016887125%2.52%0.1(n.s)
catalytic activityGO:0003824250%29.21%0.33(n.s)
nucleic acid bindingGO:0003676125%9.87%0.34(n.s)
molecular function unknownGO:0005554250%35.75%0.45(n.s)
bindingGO:0005488125%17.35%0.53(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
Noc1p-Noc2p complexGO:0030690125%0.03%1.24E-3(n.s)
Noc complexGO:0030689125%0.08%3.1E-3(n.s)
90S preribosomeGO:0030686125%0.08%3.1E-3(n.s)
nucleolar preribosome, large subunit precursorGO:0030687125%0.08%3.1E-3(n.s)
nucleolar preribosomeGO:0030685125%0.12%4.95E-3(n.s)
preribosomeGO:0030684125%0.14%5.57E-3(n.s)
intracellular non-membrane-bound organelleGO:0043232375%14.3%0.01(n.s)
non-membrane-bound organelleGO:0043228375%14.3%0.01(n.s)
nucleolusGO:0005730250%4.58%0.01(n.s)
ribonucleoprotein complexGO:0030529250%7.19%0.03(n.s)
cytosolic small ribosomal subunit (sensu Eukaryota)GO:0005843125%0.98%0.04(n.s)
eukaryotic 48S initiation complexGO:0016283125%0.98%0.04(n.s)
eukaryotic 43S preinitiation complexGO:0016282125%1.13%0.04(n.s)
small ribosomal subunitGO:0015935125%1.52%0.06(n.s)
intracellular membrane-bound organelleGO:00432314100%55.65%0.1(n.s)
membrane-bound organelleGO:00432274100%55.65%0.1(n.s)
cytosolic ribosome (sensu Eukaryota)GO:0005830125%2.65%0.1(n.s)
mitochondrionGO:0005739250%15.78%0.12(n.s)
organelleGO:00432264100%60.56%0.13(n.s)
intracellular organelleGO:00432294100%60.56%0.13(n.s)
ribosomeGO:0005840125%4.4%0.16(n.s)
protein complexGO:0043234250%21.07%0.2(n.s)
cytosolGO:0005829125%10.08%0.35(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
nucleusGO:0005634250%31.01%0.37(n.s)
cytoplasmGO:0005737375%55.64%0.4(n.s)
cellGO:00056234100%83.5%0.49(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_42 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nuclear mRNA splicing, via spliceosomeGO:00003983100%1.5%3.29E-6(5.32E-3)
RNA splicing, via transesterification reactions with bulged adenosine as nucleophileGO:00003773100%1.52%3.39E-6(5.48E-3)
RNA splicing, via transesterification reactionsGO:00003753100%1.63%4.18E-6(6.76E-3)
RNA splicingGO:00083803100%1.95%7.26E-6(0.01)
mRNA processingGO:00063973100%2.03%8.17E-6(0.01)
mRNA metabolismGO:00160713100%2.85%2.28E-5(0.04)
RNA processingGO:00063963100%5.33%1.5E-4(0.24)
RNA metabolismGO:00160703100%8.32%5.73E-4(0.93)
mRNA splice site selectionGO:0006376133.33%0.05%1.39E-3(n.s)
mRNA catabolism, nonsense-mediated decayGO:0000184133.33%0.14%4.18E-3(n.s)
spliceosome assemblyGO:0000245133.33%0.23%6.96E-3(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061393100%23.17%0.01(n.s)
biopolymer metabolismGO:00432833100%25.06%0.02(n.s)
mRNA catabolismGO:0006402133.33%0.85%0.03(n.s)
RNA catabolismGO:0006401133.33%0.99%0.03(n.s)
protein complex assemblyGO:0006461133.33%2.26%0.07(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular macromolecule catabolismGO:0044265133.33%4.51%0.13(n.s)
macromolecule catabolismGO:0009057133.33%4.83%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
macromolecule metabolismGO:0043170266.67%26.04%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mRNA bindingGO:0003729266.67%0.5%7.12E-5(0.12)
RNA bindingGO:00037233100%5.96%2.11E-4(0.34)
nucleic acid bindingGO:00036763100%9.87%9.56E-4(n.s)
bindingGO:00054883100%17.35%5.21E-3(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
commitment complexGO:0000243266.67%0.22%1.31E-5(0.02)
spliceosome complexGO:0005681266.67%1.15%3.86E-4(0.62)
snRNA cap binding complexGO:0005846133.33%0.03%9.29E-4(n.s)
snRNP U1GO:0005685133.33%0.17%5.1E-3(n.s)
ribonucleoprotein complexGO:0030529266.67%7.19%0.01(n.s)
major (U2-dependent) spliceosomeGO:0005684133.33%0.57%0.02(n.s)
small nuclear ribonucleoprotein complexGO:0030532133.33%0.99%0.03(n.s)
nucleusGO:00056343100%31.01%0.03(n.s)
protein complexGO:0043234266.67%21.07%0.11(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
mitochondrionGO:0005739133.33%15.78%0.4(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cytoplasmGO:0005737266.67%55.64%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_43 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
fatty acid biosynthesisGO:0006633133.33%0.19%5.57E-3(n.s)
carboxylic acid biosynthesisGO:0046394133.33%0.26%7.88E-3(n.s)
organic acid biosynthesisGO:0016053133.33%0.26%7.88E-3(n.s)
fatty acid metabolismGO:0006631133.33%0.67%0.02(n.s)
protein foldingGO:0006457133.33%1.04%0.03(n.s)
aerobic respirationGO:0009060133.33%1.27%0.04(n.s)
cellular respirationGO:0045333133.33%1.35%0.04(n.s)
lipid biosynthesisGO:0008610133.33%1.92%0.06(n.s)
energy derivation by oxidation of organic compoundsGO:0015980133.33%3.04%0.09(n.s)
cellular lipid metabolismGO:0044255133.33%3.16%0.09(n.s)
lipid metabolismGO:0006629133.33%3.38%0.1(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
organic acid metabolismGO:0006082133.33%4.6%0.13(n.s)
carboxylic acid metabolismGO:0019752133.33%4.6%0.13(n.s)
cellular biosynthesisGO:0044249133.33%17.05%0.43(n.s)
biosynthesisGO:0009058133.33%18.28%0.45(n.s)
primary metabolismGO:0044238266.67%48.71%0.48(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
enoyl-[acyl-carrier protein] reductase activityGO:0016631133.33%0.03%9.29E-4(n.s)
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptorGO:0016628133.33%0.14%4.18E-3(n.s)
cis-trans isomerase activityGO:0016859133.33%0.2%6.03E-3(n.s)
peptidyl-prolyl cis-trans isomerase activityGO:0003755133.33%0.2%6.03E-3(n.s)
oxidoreductase activity, acting on the CH-CH group of donorsGO:0016627133.33%0.29%8.8E-3(n.s)
isomerase activityGO:0016853133.33%0.81%0.02(n.s)
oxidoreductase activityGO:0016491133.33%3.73%0.11(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_40 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsGO:0016810150%0.93%0.02(n.s)
hydrolase activityGO:0016787150%11.45%0.22(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_5 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial transportGO:0006839150%0.17%3.41E-3(n.s)
intracellular transportGO:0046907150%7.53%0.14(n.s)
transportGO:0006810150%14.27%0.26(n.s)
establishment of localizationGO:0051234150%14.39%0.27(n.s)
localizationGO:0051179150%14.82%0.27(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
intracellular transporter activityGO:0005478150%0.46%9.27E-3(n.s)
organic acid transporter activityGO:0005342150%0.79%0.02(n.s)
transporter activityGO:0005215150%6.64%0.13(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
mitochondrial inner membraneGO:0005743150%2.43%0.05(n.s)
inner membraneGO:0019866150%2.43%0.05(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_146 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
methionyl-tRNA aminoacylationGO:00064313100%0.05%2.23E-11(3.6E-8)
tRNA aminoacylationGO:00430393100%0.46%9.06E-8(1.46E-4)
amino acid activationGO:00430383100%0.46%9.06E-8(1.46E-4)
tRNA aminoacylation for protein translationGO:00064183100%0.46%9.06E-8(1.46E-4)
tRNA modificationGO:00064003100%1.02%1.02E-6(1.65E-3)
tRNA metabolismGO:00063993100%1.6%3.95E-6(6.38E-3)
RNA modificationGO:00094513100%2.42%1.38E-5(0.02)
amino acid metabolismGO:00065203100%2.82%2.2E-5(0.04)
amino acid and derivative metabolismGO:00065193100%3.05%2.8E-5(0.05)
amine metabolismGO:00093083100%3.38%3.8E-5(0.06)
nitrogen compound metabolismGO:00068073100%3.66%4.83E-5(0.08)
organic acid metabolismGO:00060823100%4.6%9.64E-5(0.16)
carboxylic acid metabolismGO:00197523100%4.6%9.64E-5(0.16)
translationGO:00430373100%6.47%2.7E-4(0.44)
RNA metabolismGO:00160703100%8.32%5.73E-4(0.93)
biopolymer modificationGO:00434123100%9.25%7.87E-4(n.s)
protein biosynthesisGO:00064123100%12.16%1.79E-3(n.s)
macromolecule biosynthesisGO:00090593100%13.04%2.21E-3(n.s)
cellular biosynthesisGO:00442493100%17.05%4.95E-3(n.s)
biosynthesisGO:00090583100%18.28%6.09E-3(n.s)
cellular protein metabolismGO:00442673100%21.7%0.01(n.s)
protein metabolismGO:00195383100%22.06%0.01(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061393100%23.17%0.01(n.s)
cellular macromolecule metabolismGO:00442603100%24.52%0.01(n.s)
biopolymer metabolismGO:00432833100%25.06%0.02(n.s)
macromolecule metabolismGO:00431703100%26.04%0.02(n.s)
translational initiationGO:0006413133.33%0.74%0.02(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
methionine-tRNA ligase activityGO:0004825266.67%0.03%1.44E-7(2.33E-4)
ligase activity, forming carbon-oxygen bondsGO:0016875266.67%0.56%9.04E-5(0.15)
tRNA ligase activityGO:0004812266.67%0.56%9.04E-5(0.15)
ligase activity, forming aminoacyl-tRNA and related compoundsGO:0016876266.67%0.56%9.04E-5(0.15)
RNA ligase activityGO:0008452266.67%0.57%9.55E-5(0.15)
ligase activity, forming phosphoric ester bondsGO:0016886266.67%0.62%1.12E-4(0.18)
methionyl-tRNA formyltransferase activityGO:0004479133.33%0.02%**
ligase activityGO:0016874266.67%1.89%1.05E-3(n.s)
hydroxymethyl-, formyl- and related transferase activityGO:0016742133.33%0.08%2.32E-3(n.s)
glycine hydroxymethyltransferase activityGO:0004372133.33%0.11%3.25E-3(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
methyltransferase activityGO:0008168133.33%1.1%0.03(n.s)
transferase activity, transferring one-carbon groupsGO:0016741133.33%1.13%0.03(n.s)
transferase activityGO:0016740133.33%10.13%0.27(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
methionyl glutamyl tRNA synthetase complexGO:0017102133.33%0.05%1.39E-3(n.s)
unlocalized protein complexGO:0005941133.33%0.57%0.02(n.s)
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
protein complexGO:0043234133.33%21.07%0.51(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_144 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytochrome c-heme linkageGO:0018063150%0.05%9.29E-4(n.s)
protein-tetrapyrrole linkageGO:0017006150%0.05%9.29E-4(n.s)
protein-heme linkageGO:0017003150%0.05%9.29E-4(n.s)
cytochrome complex assemblyGO:0017004150%0.08%1.55E-3(n.s)
chromatin silencing at ribosomal DNAGO:0000183150%0.22%4.33E-3(n.s)
nicotinamide metabolismGO:0006769150%0.46%9.27E-3(n.s)
pyridine nucleotide metabolismGO:0019362150%0.51%0.01(n.s)
oxidoreduction coenzyme metabolismGO:0006733150%0.67%0.01(n.s)
vitamin metabolismGO:0006766150%1.13%0.02(n.s)
water-soluble vitamin metabolismGO:0006767150%1.13%0.02(n.s)
negative regulation of gene expression, epigeneticGO:0045814150%1.19%0.02(n.s)
chromatin silencingGO:0006342150%1.19%0.02(n.s)
gene silencingGO:0016458150%1.19%0.02(n.s)
heterochromatin formationGO:0031507150%1.19%0.02(n.s)
regulation of gene expression, epigeneticGO:0040029150%1.27%0.03(n.s)
chromatin assemblyGO:0031497150%1.27%0.03(n.s)
nucleotide metabolismGO:0009117150%1.38%0.03(n.s)
chromatin assembly or disassemblyGO:0006333150%1.52%0.03(n.s)
coenzyme metabolismGO:0006732150%1.81%0.04(n.s)
negative regulation of transcription, DNA-dependentGO:0045892150%1.89%0.04(n.s)
negative regulation of transcriptionGO:0016481150%1.95%0.04(n.s)
chromatin remodelingGO:0006338150%2.01%0.04(n.s)
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0045934150%2.11%0.04(n.s)
cofactor metabolismGO:0051186150%2.26%0.04(n.s)
protein complex assemblyGO:0006461150%2.26%0.04(n.s)
negative regulation of cellular metabolismGO:0031324150%2.29%0.05(n.s)
negative regulation of metabolismGO:0009892150%2.4%0.05(n.s)
negative regulation of cellular physiological processGO:0051243150%2.59%0.05(n.s)
negative regulation of cellular processGO:0048523150%2.59%0.05(n.s)
negative regulation of physiological processGO:0043118150%2.62%0.05(n.s)
negative regulation of biological processGO:0048519150%2.71%0.05(n.s)
chromatin modificationGO:0016568150%2.77%0.05(n.s)
DNA packagingGO:0006323150%3.14%0.06(n.s)
establishment and/or maintenance of chromatin architectureGO:0006325150%3.14%0.06(n.s)
biopolymer metabolismGO:00432832100%25.06%0.06(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001150%3.72%0.07(n.s)
chromosome organization and biogenesisGO:0051276150%3.9%0.08(n.s)
regulation of transcription, DNA-dependentGO:0006355150%4.68%0.09(n.s)
regulation of transcriptionGO:0045449150%4.96%0.1(n.s)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0019219150%5.24%0.1(n.s)
developmentGO:0007275150%5.73%0.11(n.s)
regulation of cellular metabolismGO:0031323150%5.98%0.12(n.s)
regulation of metabolismGO:0019222150%6.37%0.12(n.s)
protein modificationGO:0006464150%6.68%0.13(n.s)
transcription, DNA-dependentGO:0006351150%6.78%0.13(n.s)
transcriptionGO:0006350150%7.43%0.14(n.s)
regulation of cellular physiological processGO:0051244150%8.49%0.16(n.s)
regulation of cellular processGO:0050794150%8.52%0.16(n.s)
DNA metabolismGO:0006259150%8.58%0.16(n.s)
regulation of physiological processGO:0050791150%8.77%0.17(n.s)
regulation of biological processGO:0050789150%8.97%0.17(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
primary metabolismGO:00442382100%48.71%0.24(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nicotinamide N-methyltransferase activityGO:0008112150%0.02%**
holocytochrome-c synthase activityGO:0004408150%0.03%6.2E-4(n.s)
carbon-sulfur lyase activityGO:0016846150%0.14%2.79E-3(n.s)
N-methyltransferase activityGO:0008170150%0.2%4.02E-3(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:0008757150%0.77%0.02(n.s)
methyltransferase activityGO:0008168150%1.1%0.02(n.s)
transferase activity, transferring one-carbon groupsGO:0016741150%1.13%0.02(n.s)
lyase activityGO:0016829150%1.27%0.03(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial intermembrane spaceGO:0005758150%0.39%7.73E-3(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_145 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
one-carbon compound metabolismGO:0006730150%0.19%3.71E-3(n.s)
biological process unknownGO:0000004150%25.64%0.45(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
cellular physiological processGO:0050875150%71.65%0.92(n.s)
cellular processGO:0009987150%72.29%0.92(n.s)
physiological processGO:0007582150%73.68%0.93(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
tetrahydrofolylpolyglutamate synthase activityGO:00043262100%0.03%4.8E-8(7.76E-5)
acid-amino acid ligase activityGO:00168812100%0.74%5.41E-5(0.09)
ligase activity, forming carbon-nitrogen bondsGO:00168792100%1.07%1.13E-4(0.18)
ligase activityGO:00168742100%1.89%3.54E-4(0.57)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_142 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
double-strand break repair via break-induced replicationGO:0000727150%0.09%1.86E-3(n.s)
double-strand break repair via single-strand annealingGO:0045002150%0.17%3.41E-3(n.s)
telomerase-independent telomere maintenanceGO:0000722150%0.2%4.02E-3(n.s)
double-strand break repair via homologous recombinationGO:0000724150%0.28%5.57E-3(n.s)
recombinational repairGO:0000725150%0.29%5.88E-3(n.s)
mitotic recombinationGO:0006312150%0.39%7.73E-3(n.s)
non-recombinational repairGO:0000726150%0.43%8.66E-3(n.s)
double-strand break repairGO:0006302150%0.64%0.01(n.s)
telomere maintenanceGO:0000723150%0.65%0.01(n.s)
DNA repairGO:0006281150%2.32%0.05(n.s)
response to DNA damage stimulusGO:0006974150%2.73%0.05(n.s)
response to endogenous stimulusGO:0009719150%2.82%0.06(n.s)
DNA recombinationGO:0006310150%2.91%0.06(n.s)
chromosome organization and biogenesis (sensu Eukaryota)GO:0007001150%3.72%0.07(n.s)
chromosome organization and biogenesisGO:0051276150%3.9%0.08(n.s)
response to stressGO:0006950150%6.09%0.12(n.s)
cell cycleGO:0007049150%6.12%0.12(n.s)
response to stimulusGO:0050896150%8.41%0.16(n.s)
DNA metabolismGO:0006259150%8.58%0.16(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139150%23.17%0.41(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
cellular metabolismGO:0044237150%52.12%0.77(n.s)
metabolismGO:0008152150%52.93%0.78(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA strand annealing activityGO:0000739150%0.03%6.2E-4(n.s)
double-stranded DNA bindingGO:0003690150%0.14%2.79E-3(n.s)
single-stranded DNA bindingGO:0003697150%0.19%3.71E-3(n.s)
DNA bindingGO:0003677150%3.18%0.06(n.s)
protein bindingGO:0005515150%7.39%0.14(n.s)
nucleic acid bindingGO:0003676150%9.87%0.19(n.s)
bindingGO:0005488150%17.35%0.32(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739150%15.78%0.29(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
nucleusGO:0005634150%31.01%0.52(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_143 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
integral to membraneGO:0016021150%3.55%0.07(n.s)
intrinsic to membraneGO:0031224150%3.61%0.07(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cellular component unknownGO:0008372150%15.74%0.29(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
intracellularGO:0005622150%77.03%0.95(n.s)
cellGO:0005623150%83.5%0.97(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_140 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
drug transportGO:0015893125%0.2%8.03E-3(n.s)
response to drugGO:0042493125%0.48%0.02(n.s)
processing of 20S pre-rRNAGO:0030490125%0.71%0.03(n.s)
post-Golgi transportGO:0006892125%0.79%0.03(n.s)
Golgi vesicle transportGO:0048193125%2.18%0.08(n.s)
response to chemical substanceGO:0042221125%2.18%0.08(n.s)
transportGO:0006810250%14.27%0.1(n.s)
establishment of localizationGO:0051234250%14.39%0.1(n.s)
rRNA processingGO:0006364125%2.71%0.1(n.s)
localizationGO:0051179250%14.82%0.11(n.s)
secretory pathwayGO:0045045125%3.13%0.12(n.s)
secretionGO:0046903125%3.24%0.12(n.s)
ribosome biogenesisGO:0007046125%3.3%0.13(n.s)
response to abiotic stimulusGO:0009628125%3.52%0.13(n.s)
intracellular protein transportGO:0006886125%3.7%0.14(n.s)
protein transportGO:0015031125%3.79%0.14(n.s)
response to external stimulusGO:0009605125%3.87%0.15(n.s)
cytoplasm organization and biogenesisGO:0007028125%3.9%0.15(n.s)
ribosome biogenesis and assemblyGO:0042254125%3.9%0.15(n.s)
rRNA metabolismGO:0016072125%3.92%0.15(n.s)
establishment of protein localizationGO:0045184125%3.95%0.15(n.s)
vesicle-mediated transportGO:0016192125%4.34%0.16(n.s)
protein localizationGO:0008104125%4.37%0.16(n.s)
RNA processingGO:0006396125%5.33%0.2(n.s)
intracellular transportGO:0046907125%7.53%0.27(n.s)
biological process unknownGO:0000004250%25.64%0.27(n.s)
RNA metabolismGO:0016070125%8.32%0.29(n.s)
response to stimulusGO:0050896125%8.41%0.3(n.s)
organelle organization and biogenesisGO:0006996125%15.69%0.49(n.s)
cell organization and biogenesisGO:0016043125%17.98%0.55(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:0006139125%23.17%0.65(n.s)
biopolymer metabolismGO:0043283125%25.06%0.68(n.s)
cellular physiological processGO:0050875250%71.65%0.93(n.s)
primary metabolismGO:0044238125%48.71%0.93(n.s)
cellular processGO:0009987250%72.29%0.93(n.s)
physiological processGO:0007582250%73.68%0.94(n.s)
cellular metabolismGO:0044237125%52.12%0.95(n.s)
metabolismGO:0008152125%52.93%0.95(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesGO:0016820250%0.87%4.39E-4(0.71)
ATPase activity, coupled to transmembrane movement of substancesGO:0042626250%0.87%4.39E-4(0.71)
ATPase activity, coupledGO:0042623250%1.58%1.45E-3(n.s)
xenobiotic-transporting ATPase activityGO:0008559125%0.08%3.1E-3(n.s)
xenobiotic transporter activityGO:0042910125%0.08%3.1E-3(n.s)
ATPase activityGO:0016887250%2.52%3.68E-3(n.s)
phospholipid-translocating ATPase activityGO:0004012125%0.09%3.71E-3(n.s)
aminophospholipid transporter activityGO:0015247125%0.09%3.71E-3(n.s)
nucleoside-triphosphatase activityGO:0017111250%3.42%6.69E-3(n.s)
phospholipid transporter activityGO:0005548125%0.17%6.8E-3(n.s)
multidrug transporter activityGO:0015239125%0.19%7.42E-3(n.s)
pyrophosphatase activityGO:0016462250%3.67%7.67E-3(n.s)
hydrolase activity, acting on acid anhydridesGO:0016817250%3.69%7.73E-3(n.s)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:0016818250%3.69%7.73E-3(n.s)
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanismGO:0015662125%0.23%9.26E-3(n.s)
drug transporter activityGO:0015238125%0.23%9.26E-3(n.s)
lipid transporter activityGO:0005319125%0.23%9.26E-3(n.s)
lipid bindingGO:0008289125%0.36%0.01(n.s)
P-P-bond-hydrolysis-driven transporter activityGO:0015405125%0.45%0.02(n.s)
ATPase activity, coupled to transmembrane movement of ionsGO:0042625125%0.46%0.02(n.s)
transporter activityGO:0005215250%6.64%0.02(n.s)
primary active transporter activityGO:0015399125%0.77%0.03(n.s)
carrier activityGO:0005386125%1.64%0.06(n.s)
hydrolase activityGO:0016787250%11.45%0.07(n.s)
cation transporter activityGO:0008324125%1.89%0.07(n.s)
ion transporter activityGO:0015075125%2.21%0.09(n.s)
catalytic activityGO:0003824250%29.21%0.33(n.s)
bindingGO:0005488125%17.35%0.53(n.s)
molecular function unknownGO:0005554125%35.75%0.83(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
trans-Golgi network transport vesicleGO:0030140125%0.12%4.95E-3(n.s)
transport vesicleGO:0030133125%0.19%7.42E-3(n.s)
plasma membraneGO:0005886250%3.67%7.67E-3(n.s)
clathrin-coated vesicleGO:0030136125%0.25%9.88E-3(n.s)
Golgi vesicleGO:0005798125%0.26%0.01(n.s)
Golgi membraneGO:0000139125%0.39%0.02(n.s)
coated vesicleGO:0030135125%0.79%0.03(n.s)
cytoplasmic vesicleGO:0031410125%1.16%0.05(n.s)
cytoplasmic membrane-bound vesicleGO:0016023125%1.16%0.05(n.s)
Golgi apparatusGO:0005794125%2.01%0.08(n.s)
budGO:0005933125%2.12%0.08(n.s)
cytoplasmGO:00057374100%55.64%0.1(n.s)
membraneGO:0016020250%15.38%0.11(n.s)
mitochondrionGO:0005739250%15.78%0.12(n.s)
endomembrane systemGO:0012505125%3.7%0.14(n.s)
organelle membraneGO:0031090125%8.58%0.3(n.s)
intracellularGO:00056224100%77.03%0.35(n.s)
intracellular membrane-bound organelleGO:0043231375%55.65%0.4(n.s)
membrane-bound organelleGO:0043227375%55.65%0.4(n.s)
organelleGO:0043226375%60.56%0.48(n.s)
intracellular organelleGO:0043229375%60.56%0.48(n.s)
cellGO:00056234100%83.5%0.49(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_141 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055542100%35.75%0.13(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cellular component unknownGO:0008372150%15.74%0.29(n.s)
mitochondrionGO:0005739150%15.78%0.29(n.s)
cytoplasmGO:0005737150%55.64%0.8(n.s)
intracellular membrane-bound organelleGO:0043231150%55.65%0.8(n.s)
membrane-bound organelleGO:0043227150%55.65%0.8(n.s)
organelleGO:0043226150%60.56%0.84(n.s)
intracellular organelleGO:0043229150%60.56%0.84(n.s)
intracellularGO:0005622150%77.03%0.95(n.s)
cellGO:0005623150%83.5%0.97(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_148 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
electron transportGO:00061182100%0.48%2.23E-5(0.04)
generation of precursor metabolites and energyGO:00060912100%3.5%1.22E-3(n.s)
ergosterol metabolismGO:0008204150%0.39%7.73E-3(n.s)
ergosterol biosynthesisGO:0006696150%0.39%7.73E-3(n.s)
sterol biosynthesisGO:0016126150%0.45%8.96E-3(n.s)
steroid biosynthesisGO:0006694150%0.56%0.01(n.s)
sterol metabolismGO:0016125150%0.57%0.01(n.s)
steroid metabolismGO:0008202150%0.7%0.01(n.s)
response to oxidative stressGO:0006979150%0.79%0.02(n.s)
oxygen and reactive oxygen species metabolismGO:0006800150%0.82%0.02(n.s)
transportGO:00068102100%14.27%0.02(n.s)
establishment of localizationGO:00512342100%14.39%0.02(n.s)
response to biotic stimulusGO:0009607150%1.08%0.02(n.s)
localizationGO:00511792100%14.82%0.02(n.s)
lipid biosynthesisGO:0008610150%1.92%0.04(n.s)
alcohol metabolismGO:0006066150%2.43%0.05(n.s)
cellular lipid metabolismGO:0044255150%3.16%0.06(n.s)
lipid metabolismGO:0006629150%3.38%0.07(n.s)
response to stressGO:0006950150%6.09%0.12(n.s)
response to stimulusGO:0050896150%8.41%0.16(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytochrome-b5 reductase activityGO:00041282100%0.03%4.8E-8(7.76E-5)
oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptorGO:00166522100%0.03%4.8E-8(7.76E-5)
oxidoreductase activity, acting on NADH or NADPHGO:00166512100%0.14%1.73E-6(2.79E-3)
electron transporter activityGO:00054892100%0.34%1.11E-5(0.02)
oxidoreductase activityGO:00164912100%3.73%1.39E-3(n.s)
transporter activityGO:00052152100%6.64%4.41E-3(n.s)
catalytic activityGO:00038242100%29.21%0.09(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
microsomeGO:0005792150%0.25%4.95E-3(n.s)
vesicular fractionGO:0042598150%0.25%4.95E-3(n.s)
mitochondrial intermembrane spaceGO:0005758150%0.39%7.73E-3(n.s)
mitochondrial outer membraneGO:0005741150%0.53%0.01(n.s)
outer membraneGO:0019867150%0.53%0.01(n.s)
membrane fractionGO:0005624150%1.22%0.02(n.s)
mitochondrionGO:00057392100%15.78%0.02(n.s)
cell fractionGO:0000267150%1.72%0.03(n.s)
mitochondrial membraneGO:0005740150%3.16%0.06(n.s)
organelle membraneGO:0031090150%8.58%0.16(n.s)
membraneGO:0016020150%15.38%0.28(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_77 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000043100%25.64%0.02(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
molecular function unknownGO:00055543100%35.75%0.05(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_76 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
protein kinase activityGO:0004672150%1.97%0.04(n.s)
phosphotransferase activity, alcohol group as acceptorGO:0016773150%2.62%0.05(n.s)
kinase activityGO:0016301150%3.05%0.06(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772150%5.19%0.1(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_75 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lipid metabolismGO:00066293100%3.38%3.8E-5(0.06)
protein myristoylationGO:0018377133.33%0.08%2.32E-3(n.s)
N-terminal protein myristoylationGO:0006499133.33%0.08%2.32E-3(n.s)
protein amino acid myristoylationGO:0018319133.33%0.08%2.32E-3(n.s)
lipid transportGO:0006869133.33%0.31%9.27E-3(n.s)
ergosterol metabolismGO:0008204133.33%0.39%0.01(n.s)
ergosterol biosynthesisGO:0006696133.33%0.39%0.01(n.s)
sterol biosynthesisGO:0016126133.33%0.45%0.01(n.s)
lipoprotein metabolismGO:0042157133.33%0.56%0.02(n.s)
lipoprotein biosynthesisGO:0042158133.33%0.56%0.02(n.s)
steroid biosynthesisGO:0006694133.33%0.56%0.02(n.s)
protein lipidationGO:0006497133.33%0.56%0.02(n.s)
sterol metabolismGO:0016125133.33%0.57%0.02(n.s)
steroid metabolismGO:0008202133.33%0.7%0.02(n.s)
lipid biosynthesisGO:0008610133.33%1.92%0.06(n.s)
alcohol metabolismGO:0006066133.33%2.43%0.07(n.s)
biosynthesisGO:0009058266.67%18.28%0.09(n.s)
cellular lipid metabolismGO:0044255133.33%3.16%0.09(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
protein modificationGO:0006464133.33%6.68%0.19(n.s)
biopolymer modificationGO:0043412133.33%9.25%0.25(n.s)
protein biosynthesisGO:0006412133.33%12.16%0.32(n.s)
macromolecule biosynthesisGO:0009059133.33%13.04%0.34(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular biosynthesisGO:0044249133.33%17.05%0.43(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biopolymer metabolismGO:0043283133.33%25.06%0.58(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
sterol 24-C-methyltransferase activityGO:0003838133.33%0.02%**
C-methyltransferase activityGO:0008169133.33%0.05%1.39E-3(n.s)
long-chain-fatty-acid-CoA ligase activityGO:0004467133.33%0.08%2.32E-3(n.s)
fatty-acid ligase activityGO:0015645133.33%0.08%2.32E-3(n.s)
serine hydrolase activityGO:0017171133.33%0.09%2.79E-3(n.s)
ligase activity, forming carbon-sulfur bondsGO:0016877133.33%0.14%4.18E-3(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:0008757133.33%0.77%0.02(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
methyltransferase activityGO:0008168133.33%1.1%0.03(n.s)
transferase activity, transferring one-carbon groupsGO:0016741133.33%1.13%0.03(n.s)
ligase activityGO:0016874133.33%1.89%0.06(n.s)
transferase activityGO:0016740133.33%10.13%0.27(n.s)
hydrolase activityGO:0016787133.33%11.45%0.31(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
lipid particleGO:00058113100%0.51%1.22E-7(1.97E-4)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
endoplasmic reticulumGO:0005783133.33%5.84%0.17(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_74 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
N-terminal peptidyl-methionine acetylationGO:0017196150%0.05%9.29E-4(n.s)
peptidyl-methionine modificationGO:0018206150%0.05%9.29E-4(n.s)
N-terminal protein amino acid modificationGO:0031365150%0.09%1.86E-3(n.s)
N-terminal protein amino acid acetylationGO:0006474150%0.09%1.86E-3(n.s)
peptide or protein amino-terminal blockingGO:0018409150%0.09%1.86E-3(n.s)
peptidyl-amino acid modificationGO:0018193150%0.26%5.26E-3(n.s)
thiamin biosynthesisGO:0009228150%0.29%5.88E-3(n.s)
thiamin and derivative biosynthesisGO:0042724150%0.31%6.19E-3(n.s)
thiamin metabolismGO:0006772150%0.31%6.19E-3(n.s)
thiamin and derivative metabolismGO:0042723150%0.34%6.8E-3(n.s)
mitochondrial genome maintenanceGO:0000002150%0.42%8.35E-3(n.s)
protein amino acid acetylationGO:0006473150%0.59%0.01(n.s)
vitamin biosynthesisGO:0009110150%0.59%0.01(n.s)
water-soluble vitamin biosynthesisGO:0042364150%0.59%0.01(n.s)
water-soluble vitamin metabolismGO:0006767150%1.13%0.02(n.s)
vitamin metabolismGO:0006766150%1.13%0.02(n.s)
mitochondrion organization and biogenesisGO:0007005150%1.47%0.03(n.s)
protein modificationGO:0006464150%6.68%0.13(n.s)
biopolymer modificationGO:0043412150%9.25%0.18(n.s)
cellular metabolismGO:00442372100%52.12%0.27(n.s)
metabolismGO:00081522100%52.93%0.28(n.s)
organelle organization and biogenesisGO:0006996150%15.69%0.29(n.s)
cellular biosynthesisGO:0044249150%17.05%0.31(n.s)
cell organization and biogenesisGO:0016043150%17.98%0.33(n.s)
biosynthesisGO:0009058150%18.28%0.33(n.s)
cellular protein metabolismGO:0044267150%21.7%0.39(n.s)
protein metabolismGO:0019538150%22.06%0.39(n.s)
cellular macromolecule metabolismGO:0044260150%24.52%0.43(n.s)
biopolymer metabolismGO:0043283150%25.06%0.44(n.s)
macromolecule metabolismGO:0043170150%26.04%0.45(n.s)
cellular physiological processGO:00508752100%71.65%0.51(n.s)
cellular processGO:00099872100%72.29%0.52(n.s)
physiological processGO:00075822100%73.68%0.54(n.s)
primary metabolismGO:0044238150%48.71%0.74(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
peptide alpha-N-acetyltransferase activityGO:0004596150%0.11%2.17E-3(n.s)
N-acetyltransferase activityGO:0008080150%0.53%0.01(n.s)
N-acyltransferase activityGO:0016410150%0.59%0.01(n.s)
acetyltransferase activityGO:0016407150%0.71%0.01(n.s)
acyltransferase activityGO:0008415150%1.19%0.02(n.s)
transferase activity, transferring groups other than amino-acyl groupsGO:0016747150%1.19%0.02(n.s)
transferase activity, transferring acyl groupsGO:0016746150%1.43%0.03(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytosolGO:0005829150%10.08%0.19(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_73 (n = 2)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
biological process unknownGO:00000042100%25.64%0.07(n.s)
biological_processGO:00081502100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
kinase activityGO:0016301150%3.05%0.06(n.s)
transferase activity, transferring phosphorus-containing groupsGO:0016772150%5.19%0.1(n.s)
transferase activityGO:0016740150%10.13%0.19(n.s)
catalytic activityGO:0003824150%29.21%0.5(n.s)
molecular function unknownGO:0005554150%35.75%0.59(n.s)
molecular_functionGO:00036742100%99.44%0.99(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:00057392100%15.78%0.02(n.s)
cytoplasmGO:00057372100%55.64%0.31(n.s)
intracellular membrane-bound organelleGO:00432312100%55.65%0.31(n.s)
membrane-bound organelleGO:00432272100%55.65%0.31(n.s)
organelleGO:00432262100%60.56%0.37(n.s)
intracellular organelleGO:00432292100%60.56%0.37(n.s)
intracellularGO:00056222100%77.03%0.59(n.s)
cellGO:00056232100%83.5%0.7(n.s)
cellular_componentGO:00055752100%99.61%0.99(n.s)

 

 

cluster_72 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
DNA metabolismGO:00062593100%8.58%6.29E-4(n.s)
DNA repairGO:0006281266.67%2.32%1.58E-3(n.s)
response to DNA damage stimulusGO:0006974266.67%2.73%2.18E-3(n.s)
response to endogenous stimulusGO:0009719266.67%2.82%2.33E-3(n.s)
DNA catabolismGO:0006308133.33%0.17%5.1E-3(n.s)
maintenance of fidelity during DNA-dependent DNA replicationGO:0045005133.33%0.31%9.27E-3(n.s)
mismatch repairGO:0006298133.33%0.31%9.27E-3(n.s)
response to stressGO:0006950266.67%6.09%0.01(n.s)
nucleobase, nucleoside, nucleotide and nucleic acid metabolismGO:00061393100%23.17%0.01(n.s)
biopolymer metabolismGO:00432833100%25.06%0.02(n.s)
response to stimulusGO:0050896266.67%8.41%0.02(n.s)
RNA catabolismGO:0006401133.33%0.99%0.03(n.s)
DNA-dependent DNA replicationGO:0006261133.33%1.24%0.04(n.s)
DNA replicationGO:0006260133.33%1.6%0.05(n.s)
DNA recombinationGO:0006310133.33%2.91%0.08(n.s)
primary metabolismGO:00442383100%48.71%0.12(n.s)
cellular macromolecule catabolismGO:0044265133.33%4.51%0.13(n.s)
macromolecule catabolismGO:0009057133.33%4.83%0.14(n.s)
cellular metabolismGO:00442373100%52.12%0.14(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
cellular catabolismGO:0044248133.33%5.84%0.17(n.s)
catabolismGO:0009056133.33%6.16%0.17(n.s)
RNA metabolismGO:0016070133.33%8.32%0.23(n.s)
cellular physiological processGO:00508753100%71.65%0.37(n.s)
cellular processGO:00099873100%72.29%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
nuclease activityGO:00045183100%2.15%9.77E-6(0.02)
endodeoxyribonuclease activityGO:0004520266.67%0.28%2.2E-5(0.04)
deoxyribonuclease activityGO:0004536266.67%0.31%2.73E-5(0.04)
hydrolase activity, acting on ester bondsGO:00167883100%4.12%6.92E-5(0.11)
exonuclease activityGO:0004527266.67%0.51%7.58E-5(0.12)
endonuclease activityGO:0004519266.67%0.88%2.28E-4(0.37)
exodeoxyribonuclease activityGO:0004529133.33%0.03%9.29E-4(n.s)
hydrolase activityGO:00167873100%11.45%1.49E-3(n.s)
5'-3' exonuclease activityGO:0008409133.33%0.06%1.86E-3(n.s)
5'-flap endonuclease activityGO:0017108133.33%0.08%2.32E-3(n.s)
endodeoxyribonuclease activity, producing 5'-phosphomonoestersGO:0016888133.33%0.08%2.32E-3(n.s)
flap endonuclease activityGO:0048256133.33%0.08%2.32E-3(n.s)
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersGO:0016893133.33%0.37%0.01(n.s)
catalytic activityGO:00038243100%29.21%0.02(n.s)
ribonuclease activityGO:0004540133.33%1.55%0.05(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
mitochondrial inner membraneGO:0005743133.33%2.43%0.07(n.s)
inner membraneGO:0019866133.33%2.43%0.07(n.s)
mitochondrial membraneGO:0005740133.33%3.16%0.09(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
organelle membraneGO:0031090133.33%8.58%0.24(n.s)
membraneGO:0016020133.33%15.38%0.39(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cytoplasmGO:0005737266.67%55.64%0.58(n.s)
nucleusGO:0005634133.33%31.01%0.67(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_71 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
electron transportGO:0006118133.33%0.48%0.01(n.s)
response to oxidative stressGO:0006979133.33%0.79%0.02(n.s)
oxygen and reactive oxygen species metabolismGO:0006800133.33%0.82%0.02(n.s)
response to biotic stimulusGO:0009607133.33%1.08%0.03(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
metabolismGO:00081523100%52.93%0.15(n.s)
response to stressGO:0006950133.33%6.09%0.17(n.s)
response to stimulusGO:0050896133.33%8.41%0.23(n.s)
transportGO:0006810133.33%14.27%0.37(n.s)
establishment of localizationGO:0051234133.33%14.39%0.37(n.s)
localizationGO:0051179133.33%14.82%0.38(n.s)
physiological processGO:00075823100%73.68%0.4(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
cytochrome-c peroxidase activityGO:0004130133.33%0.02%**
fumarate reductase (NADH) activityGO:0016156133.33%0.03%9.29E-4(n.s)
electron carrier activityGO:0009055133.33%0.08%2.32E-3(n.s)
oxidoreductase activityGO:0016491266.67%3.73%4.06E-3(n.s)
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptorGO:0016628133.33%0.14%4.18E-3(n.s)
peroxidase activityGO:0004601133.33%0.26%7.88E-3(n.s)
oxidoreductase activity, acting on peroxide as acceptorGO:0016684133.33%0.26%7.88E-3(n.s)
oxidoreductase activity, acting on the CH-CH group of donorsGO:0016627133.33%0.29%8.8E-3(n.s)
antioxidant activityGO:0016209133.33%0.31%9.27E-3(n.s)
electron transporter activityGO:0005489133.33%0.34%0.01(n.s)
carrier activityGO:0005386133.33%1.64%0.05(n.s)
transporter activityGO:0005215133.33%6.64%0.19(n.s)
catalytic activityGO:0003824266.67%29.21%0.21(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrial intermembrane spaceGO:0005758266.67%0.39%4.31E-5(0.07)
mitochondrionGO:00057393100%15.78%3.92E-3(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellular membrane-bound organelleGO:00432313100%55.65%0.17(n.s)
membrane-bound organelleGO:00432273100%55.65%0.17(n.s)
organelleGO:00432263100%60.56%0.22(n.s)
intracellular organelleGO:00432293100%60.56%0.22(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 

cluster_70 (n = 4)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
phosphate transportGO:0006817125%0.15%6.18E-3(n.s)
inorganic anion transportGO:0015698125%0.25%9.88E-3(n.s)
transportGO:0006810375%14.27%0.01(n.s)
anion transportGO:0006820125%0.26%0.01(n.s)
establishment of localizationGO:0051234375%14.39%0.01(n.s)
localizationGO:0051179375%14.82%0.01(n.s)
ER-associated protein catabolismGO:0030433125%0.29%0.01(n.s)
misfolded or incompletely synthesized protein catabolismGO:0006515125%0.33%0.01(n.s)
amino acid transportGO:0006865125%0.57%0.02(n.s)
proteasomal ubiquitin-dependent protein catabolismGO:0043161125%0.7%0.03(n.s)
protein-mitochondrial targetingGO:0006626125%0.73%0.03(n.s)
amine transportGO:0015837125%0.74%0.03(n.s)
carboxylic acid transportGO:0046942125%0.77%0.03(n.s)
organic acid transportGO:0015849125%0.79%0.03(n.s)
ion transportGO:0006811125%1.64%0.06(n.s)
ubiquitin-dependent protein catabolismGO:0006511125%1.86%0.07(n.s)
modification-dependent protein catabolismGO:0019941125%1.86%0.07(n.s)
cellular protein catabolismGO:0044257125%2.42%0.09(n.s)
proteolysis and peptidolysisGO:0006508125%2.42%0.09(n.s)
protein catabolismGO:0030163125%2.74%0.11(n.s)
biopolymer catabolismGO:0043285125%2.93%0.11(n.s)
protein targetingGO:0006605125%3.42%0.13(n.s)
intracellular protein transportGO:0006886125%3.7%0.14(n.s)
protein transportGO:0015031125%3.79%0.14(n.s)
establishment of protein localizationGO:0045184125%3.95%0.15(n.s)
protein localizationGO:0008104125%4.37%0.16(n.s)
cellular macromolecule catabolismGO:0044265125%4.51%0.17(n.s)
macromolecule catabolismGO:0009057125%4.83%0.18(n.s)
cellular catabolismGO:0044248125%5.84%0.21(n.s)
catabolismGO:0009056125%6.16%0.22(n.s)
intracellular transportGO:0046907125%7.53%0.27(n.s)
cellular protein metabolismGO:0044267125%21.7%0.62(n.s)
protein metabolismGO:0019538125%22.06%0.63(n.s)
cellular macromolecule metabolismGO:0044260125%24.52%0.68(n.s)
cellular physiological processGO:0050875375%71.65%0.68(n.s)
biopolymer metabolismGO:0043283125%25.06%0.68(n.s)
cellular processGO:0009987375%72.29%0.69(n.s)
biological process unknownGO:0000004125%25.64%0.69(n.s)
macromolecule metabolismGO:0043170125%26.04%0.7(n.s)
physiological processGO:0007582375%73.68%0.72(n.s)
primary metabolismGO:0044238125%48.71%0.93(n.s)
cellular metabolismGO:0044237125%52.12%0.95(n.s)
metabolismGO:0008152125%52.93%0.95(n.s)
biological_processGO:00081504100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
Hsp70/Hsc70 protein regulator activityGO:0030192125%0.02%**
ATPase stimulator activityGO:0001671125%0.05%1.86E-3(n.s)
inorganic phosphate transporter activityGO:0005315125%0.06%2.48E-3(n.s)
phosphate transporter activityGO:0015114125%0.12%4.95E-3(n.s)
chaperone regulator activityGO:0030188125%0.12%4.95E-3(n.s)
inorganic anion transporter activityGO:0015103125%0.2%8.03E-3(n.s)
anion transporter activityGO:0008509125%0.28%0.01(n.s)
amino acid transporter activityGO:0015171125%0.5%0.02(n.s)
porter activityGO:0015291125%0.59%0.02(n.s)
electrochemical potential-driven transporter activityGO:0015290125%0.59%0.02(n.s)
transporter activityGO:0005215250%6.64%0.02(n.s)
amine transporter activityGO:0005275125%0.64%0.03(n.s)
carboxylic acid transporter activityGO:0046943125%0.74%0.03(n.s)
organic acid transporter activityGO:0005342125%0.79%0.03(n.s)
enzyme activator activityGO:0008047125%0.91%0.04(n.s)
carrier activityGO:0005386125%1.64%0.06(n.s)
ion transporter activityGO:0015075125%2.21%0.09(n.s)
enzyme regulator activityGO:0030234125%2.54%0.1(n.s)
molecular function unknownGO:0005554125%35.75%0.83(n.s)
molecular_functionGO:00036744100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
membraneGO:0016020250%15.38%0.11(n.s)
mitochondrionGO:0005739250%15.78%0.12(n.s)
mitochondrial membraneGO:0005740125%3.16%0.12(n.s)
plasma membraneGO:0005886125%3.67%0.14(n.s)
organelle membraneGO:0031090125%8.58%0.3(n.s)
cytosolGO:0005829125%10.08%0.35(n.s)
cytoplasmGO:0005737375%55.64%0.4(n.s)
cellGO:00056234100%83.5%0.49(n.s)
intracellular membrane-bound organelleGO:0043231250%55.65%0.77(n.s)
membrane-bound organelleGO:0043227250%55.65%0.77(n.s)
intracellularGO:0005622375%77.03%0.77(n.s)
organelleGO:0043226250%60.56%0.83(n.s)
intracellular organelleGO:0043229250%60.56%0.83(n.s)
cellular_componentGO:00055754100%99.61%0.98(n.s)

 

 

cluster_78 (n = 3)   Biological Process  Molecular Function  Cellular Component  Details  

Biological Process

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
translational terminationGO:0006415133.33%0.14%4.18E-3(n.s)
aerobic respirationGO:0009060133.33%1.27%0.04(n.s)
cellular respirationGO:0045333133.33%1.35%0.04(n.s)
energy derivation by oxidation of organic compoundsGO:0015980133.33%3.04%0.09(n.s)
generation of precursor metabolites and energyGO:0006091133.33%3.5%0.1(n.s)
translationGO:0043037133.33%6.47%0.18(n.s)
protein biosynthesisGO:0006412133.33%12.16%0.32(n.s)
macromolecule biosynthesisGO:0009059133.33%13.04%0.34(n.s)
cellular biosynthesisGO:0044249133.33%17.05%0.43(n.s)
biosynthesisGO:0009058133.33%18.28%0.45(n.s)
cellular protein metabolismGO:0044267133.33%21.7%0.52(n.s)
protein metabolismGO:0019538133.33%22.06%0.53(n.s)
cellular metabolismGO:0044237266.67%52.12%0.53(n.s)
metabolismGO:0008152266.67%52.93%0.54(n.s)
cellular macromolecule metabolismGO:0044260133.33%24.52%0.57(n.s)
biological process unknownGO:0000004133.33%25.64%0.59(n.s)
macromolecule metabolismGO:0043170133.33%26.04%0.6(n.s)
cellular physiological processGO:0050875266.67%71.65%0.8(n.s)
cellular processGO:0009987266.67%72.29%0.81(n.s)
physiological processGO:0007582266.67%73.68%0.83(n.s)
primary metabolismGO:0044238133.33%48.71%0.87(n.s)
biological_processGO:00081503100%99.98%1(n.s)

 


Molecular Function

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
translation release factor activityGO:0003747133.33%0.05%1.39E-3(n.s)
translation termination factor activityGO:0008079133.33%0.06%1.86E-3(n.s)
translation factor activity, nucleic acid bindingGO:0008135133.33%0.73%0.02(n.s)
S-adenosylmethionine-dependent methyltransferase activityGO:0008757133.33%0.77%0.02(n.s)
translation regulator activityGO:0045182133.33%0.9%0.03(n.s)
methyltransferase activityGO:0008168133.33%1.1%0.03(n.s)
transferase activity, transferring one-carbon groupsGO:0016741133.33%1.13%0.03(n.s)
nucleic acid bindingGO:0003676133.33%9.87%0.27(n.s)
transferase activityGO:0016740133.33%10.13%0.27(n.s)
bindingGO:0005488133.33%17.35%0.44(n.s)
catalytic activityGO:0003824133.33%29.21%0.65(n.s)
molecular function unknownGO:0005554133.33%35.75%0.73(n.s)
molecular_functionGO:00036743100%99.44%0.98(n.s)

 


Cellular Component

NameIDCountPercent (Study Genes)Percent (Population Genes)E value
mitochondrionGO:0005739266.67%15.78%0.07(n.s)
cytoplasmGO:00057373100%55.64%0.17(n.s)
intracellularGO:00056223100%77.03%0.46(n.s)
cellGO:00056233100%83.5%0.58(n.s)
intracellular membrane-bound organelleGO:0043231266.67%55.65%0.58(n.s)
membrane-bound organelleGO:0043227266.67%55.65%0.58(n.s)
organelleGO:0043226266.67%60.56%0.66(n.s)
intracellular organelleGO:0043229266.67%60.56%0.66(n.s)
cellular_componentGO:00055753100%99.61%0.99(n.s)

 

 


The Ontologizer v. 0.2 displays statistical rank scores for overrepresentation of particular GO terms in the dataset as determined by the hypergeometric distribution based on Castillo-Davis et al. (2003).

The E values shown are displayed both without correction for multiple testing and (in parentheses)corrected for multiple testing by a Bonferroni correction. This conservative correction multiplies the nominal p value by the number of tests performed, i.e. by the number of GO terms for which more than one gene (product) in the population is annotated:

Note that we do not correct for terms for which there is no annotation in the population (overrepresentation is obviously impossible) or for which only one gene in the population is annotated (statistical testing doesn't really make sense in this case). The number of annotated genes in the study group is not taken into account for multiple-testing corrections.

The Gene Ontology Consortium provides a dynamic controlled vocabulary of biological functions. Associations between genes or gene products and GO terms are available from the Gene Ontology website. Functional annotations are divided into three categories:

The terms in GO form a directed acyclic graph (DAG), such that specific terms are children of more general terms.Collaborating databases generate gene association files consisting of links between GO terms and genesor gene products. These annotations are made at the most specific level possible but genes are understood to share annotations from all ancestor terms of the specifically annotated term. The Ontologizer shows "Total Annotations" includes explicit annotations as well as inferred annotations. The explicit (direct) annotations are not shown in this page but can be seen in the XML output of the Ontologizer.

Each GO term represented by a GO_id of the form GO:nnnnnnn, where nnnnnnn is a unique zero-padded integer of seven digits, and a descriptive name. The Gene Ontology documentation offers more details.

The following files were used to generate these pages:

These pages were generated by the Ontologizer.