MODULES in extracellular Proteins

The following Postscript images show the spread of the most abundant protein modules. For fast viewing, these are also available as GIF. This collection is maintained by Peer Bork. Please send comments/suggestions to Peer.Bork@embl.org. About 2500 accesses have been registered so far. Note, that this is a test version! If you make use of the information, please quote: Bork, P. & Bairoch, A. (1995) TIBS 20(3), poster C02 "Extracellular protein modules: A proposed nomenclature"

1D Cartoons of modular extracellular proteins

Nomenclature and caption as used in the SWISS-PROT and PROSITE databases

Blood coagulation and fibrinolysis
Complement system and regulators
Selected EGF modules
Spread of CUB modules
Modules in collagens
Modules in matrix proteins
Modules in receptor protein kinases/phosphatases and other recptors
The spread of the ZP domain and the Ly6UP family
CKNOT: Dimerization modules similar to TGF-beta
Selected other modules
Modules flanking enzymes
Fn3 modules acquired by prokaryotes
The SEA module associated with O-glycosylation
PKD module, also found in prokaryotes

3D information about extracellular protein modules

3D Molscript images
1D-3D representations for Quart.Rev.Bioph.

1D Cartoons of mostly intracellular regulatory modular proteins

No rules: Spread of the ankyrin repeats
The WW domain, a signalling site in dystrophin?
PI, a phosphotyrosine-binding domain?

Last modified November 19, 1996